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| Entry: PS00177 |
General information about the entry
| Entry name [info] | TOPOISOMERASE_II |
| Accession [info] | PS00177 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE; 13-FEB-2019 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00160 |
Name and characterization of the entry
| Description [info] | DNA topoisomerase II signature. |
| Pattern [info] |
[LIVMA]-{R}-E-G-[DN]-S-A-{F}-[STAG].
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Numerical results [info]
| Total number of hits | 182 in 182 different sequences |
| Number of true positive hits | 169 in 169 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 13 in 13 different sequences |
| Number of false negative sequences | 3 |
| Number of 'partial' sequences | 2 |
| Precision (true positives / (true positives + false positives)) | 92.86 % |
| Recall (true positives / (true positives + false negatives)) | 98.26 % |
Comments [info]
| Taxonomic range [info] | Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
169 sequences
CIN4_CAEEL (G5ECQ8 ), GYRB1_ACILW (Q44088 ), GYRB2_ACILW (Q44272 ), GYRBM_ARATH (Q94BZ7 ), GYRBP_ARATH (Q9SS38 ), GYRBR_STRNV (P50074 ), GYRBS_STRNV (P50075 ), GYRB_ACIBA (Q43907 ), GYRB_ACIBZ (Q44273 ), GYRB_ACICA (Q43947 ), GYRB_ACIG6 (Q44271 ), GYRB_ACIGI (Q44274 ), GYRB_ACIHA (Q44065 ), GYRB_ACIJO (Q44081 ), GYRB_ACIJU (Q44080 ), GYRB_ACIPI (Q44270 ), GYRB_ACIS8 (Q44275 ), GYRB_ACIS9 (Q44276 ), GYRB_ACIVR (Q44277 ), GYRB_BACAN (Q9X3Y6 ), GYRB_BACCE (Q9X3Y3 ), GYRB_BACHD (O50627 ), GYRB_BACMY (Q9X3Y5 ), GYRB_BACSU (P05652 ), GYRB_BORBU (P33769 ), GYRB_BORHE (Q9ZFK1 ), GYRB_BUCAI (P57126 ), GYRB_BUCAP (P29435 ), GYRB_BUCBP (Q89B37 ), GYRB_CAMJE (O87667 ), GYRB_CAUVC (P0CAX1 ), GYRB_CAUVN (B8GXQ0 ), GYRB_CHIJA (Q9FAX2 ), GYRB_CHLMU (Q9PKK3 ), GYRB_CHLPN (Q9Z8R3 ), GYRB_CHLTR (O84193 ), GYRB_CLOAB (P94604 ), GYRB_CYTAU (Q9LCK0 ), GYRB_CYTHU (Q9LCK1 ), GYRB_ECO57 (P0AES7 ), GYRB_ECOLI (P0AES6 ), GYRB_EISEL (Q9FAX1 ), GYRB_ENTFA (Q839Z1 ), GYRB_HAEIN (P43701 ), GYRB_HALL2 (P21558 ), GYRB_HALVD (D4GZ01 ), GYRB_HELPJ (Q9ZLX3 ), GYRB_HELPY (P55992 ), GYRB_MICLC (C5C7X8 ), GYRB_MYCAT (Q9ZAQ6 ), GYRB_MYCBP (A0A0G2Q9D6), GYRB_MYCGA (P47720 ), GYRB_MYCGE (P47249 ), GYRB_MYCHP (P43053 ), GYRB_MYCLE (Q59533 ), GYRB_MYCPA (Q9L7L3 ), GYRB_MYCPN (P22447 ), GYRB_MYCS2 (A0QNE0 ), GYRB_MYCSM (P0C559 ), GYRB_MYCTA (A5TY73 ), GYRB_MYCTO (P9WG44 ), GYRB_MYCTU (P9WG45 ), GYRB_MYXXA (O33367 ), GYRB_NEIGO (P22118 ), GYRB_NICBE (Q5YLB4 ), GYRB_ORYSJ (Q5NBJ3 ), GYRB_PSEAE (Q9I7C2 ), GYRB_PSEPU (P13364 ), GYRB_RICBR (Q1RHT8 ), GYRB_RICCN (Q92H87 ), GYRB_RICFE (Q4UKX5 ), GYRB_RICPR (Q9ZCX2 ), GYRB_RICTY (Q68WF6 ), GYRB_SALTI (P0A2I4 ), GYRB_SALTY (P0A2I3 ), GYRB_SHIFL (P0AES8 ), GYRB_SPICI (P34031 ), GYRB_STAA3 (Q2FKQ1 ), GYRB_STAAC (Q5HJZ1 ), GYRB_STAAM (P66936 ), GYRB_STAAN (P66937 ), GYRB_STAAR (Q6GKU0 ), GYRB_STAAS (Q6GD85 ), GYRB_STAAU (P0A0K8 ), GYRB_STAAW (P0A0K7 ), GYRB_STAEQ (Q5HK03 ), GYRB_STAES (Q8CQK4 ), GYRB_STRCO (P35886 ), GYRB_STRP1 (Q9A0L0 ), GYRB_STRP3 (P0DG04 ), GYRB_STRP6 (Q5XD05 ), GYRB_STRP8 (Q8P1M4 ), GYRB_STRPN (P0A4L9 ), GYRB_STRPQ (P0DG05 ), GYRB_STRR6 (P0A4M0 ), GYRB_SYNY3 (P77966 ), GYRB_THEMA (P77993 ), GYRB_THET8 (Q5SHZ4 ), GYRB_TREDE (O87545 ), GYRB_TREPA (O08399 ), GYRB_VIBCH (Q9KVX3 ), GYRB_VIBPA (O51859 ), PARE_BACSU (Q59192 ), PARE_BARBK (P94281 ), PARE_BORBU (Q59189 ), PARE_CAUVC (O54479 ), PARE_ECOLI (P20083 ), PARE_ENTFA (H7C794 ), PARE_FRATH (A0A0J9WZF0), PARE_HAEIN (P43703 ), PARE_MYCCT (P50028 ), PARE_MYCGA (Q59526 ), PARE_MYCGE (P47445 ), PARE_MYCPN (P78016 ), PARE_PSEAE (Q9HUJ8 ), PARE_RICBR (Q1RK03 ), PARE_RICCN (Q92IW1 ), PARE_RICFE (Q4UKT4 ), PARE_RICPR (Q9ZDU7 ), PARE_RICTY (Q68XE1 ), PARE_SALTI (P0A2I6 ), PARE_SALTY (P0A2I5 ), PARE_STAA8 (Q2FYS5 ), PARE_STAAC (Q5HG65 ), PARE_STAAM (P66938 ), PARE_STAAN (P66939 ), PARE_STAAR (Q6GH51 ), PARE_STAAS (Q6G9K5 ), PARE_STAAU (P0C1S7 ), PARE_STAAW (P0A0K9 ), PARE_STAEQ (Q5HPI6 ), PARE_STAES (Q8CSN9 ), PARE_STRPN (Q59961 ), TOP2A_CHICK (O42130 ), TOP2A_CRIGR (P41515 ), TOP2A_HUMAN (P11388 ), TOP2A_MOUSE (Q01320 ), TOP2A_PIG (O46374 ), TOP2A_RAT (P41516 ), TOP2B_CHICK (O42131 ), TOP2B_CRILO (Q64399 ), TOP2B_HUMAN (Q02880 ), TOP2B_MOUSE (Q64511 ), TOP2M_CAEEL (P34534 ), TOP2M_DICDI (P90520 ), TOP2_ARATH (P30182 ), TOP2_ASFB7 (Q00942 ), TOP2_ASFK5 (P0C9C2 ), TOP2_ASFM2 (P34203 ), TOP2_ASFP4 (P0C9C0 ), TOP2_ASFWA (P0C9C1 ), TOP2_BOMMO (O16140 ), TOP2_CAEEL (Q23670 ), TOP2_CANGA (O93794 ), TOP2_CRIFA (P27570 ), TOP2_DICDI (Q55BP5 ), TOP2_DROME (P15348 ), TOP2_LEICH (O61078 ), TOP2_MIMIV (Q5UQE6 ), TOP2_PEA (O24308 ), TOP2_PENCH (Q9Y8G8 ), TOP2_PLAFK (P41001 ), TOP2_SCHPO (P08096 ), TOP2_TRYBB (P12531 ), TOP2_TRYCR (P30190 ), TOP2_YEAST (P06786 ), TOP4B_AQUAE (O67137 ), TOPL_BPT4 (P09176 ), TOPON_MYCS2 (A0QPN2 )» more
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| UniProtKB/Swiss-Prot False negative sequences |
3 sequences
GYRB_ARCFU (O29720 ), TOP2_CANAX (P87078 ), TOP2_PICGU (Q01879 ) |
| UniProtKB/Swiss-Prot 'Partial' sequences |
2 sequences
GYRB_PROMI (P22840 ), GYRB_RHOCA (P31860 ) |
| UniProtKB/Swiss-Prot False positive sequences |
13 sequences
ASTD_PARXL (Q141D3 ), CIPK6_ORYSJ (Q6Z9F4 ), DDL_CUPNH (Q0K6M6 ), DOM_DROME (Q9NDJ2 ), MIC60_DEBHA (Q6BXM9 ), NACA_DANRE (Q8JIU7 ), RPOA_METCA (Q605D7 ), SECA_HALHL (A1WYM9 ), SEPT9_MOUSE (Q80UG5 ), SEPT9_RAT (Q9QZR6 ), XTH9_ARATH (Q8LDW9 ), Y1130_XYLFA (Q9PE98 ), Y419_XYLFT (Q87E99 )» more |
| PDB [Detailed view] |
68 PDB
1BGW; 1BJT; 2RGR; 2XCO; 2XCQ; 2XCR; 2XCS; 2XCT; 3FOE; 3FOF; 3K9F; 3KSA; 3KSB; 3L4J; 3L4K; 3LTN; 3NUH; 3QX3; 3RAD; 3RAE; 3RAF; 4BUL; 4FM9; 4G0U; 4G0V; 4G0W; 4GFH; 4I3H; 4J3N; 4JUO; 4KOE; 4KPE; 4KPF; 4PLB; 4Z2C; 4Z2D; 4Z2E; 4Z3O; 4Z4Q; 4Z53; 5BS3; 5BS8; 5BTA; 5BTC; 5BTD; 5BTF; 5BTG; 5BTI; 5BTL; 5BTN; 5CDM; 5CDN; 5CDO; 5CDP; 5CDQ; 5CDR; 5GWI; 5GWJ; 5GWK; 5IWI; 5IWM; 5NPK; 5NPP; 5ZEN; 5ZQF; 5ZRF; 6FQS; 6FQV » more |
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