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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE entry PS00181


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PURL: https://purl.expasy.org/prosite/signature/PS00181

Direct ScanProsite submission
General information about the entry

Entry name [info] GLNA_ATP
Accession [info] PS00181
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00162

Name and characterization of the entry

Description [info] Glutamine synthetase putative ATP-binding region signature.
Pattern [info] 
K-P-[LIVMFYA]-x(3,5)-[NPAT]-[GA]-[GSTAN]-[GA]-x-H-x(3)-S.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 172 in 172 different sequences
Number of true positive hits 172 in 172 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 13
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 92.97 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 172 sequences 

3HAPM_CUPPJ (Q46ZL2), GLN11_ARATH (Q56WN1), GLN11_ORYSJ (P14656), 

GLN12_ARATH (Q8LCE1), GLN12_ORYSJ (P14654), GLN13_ARATH (Q9LVI8), 
GLN13_ORYSJ (Q4W8D0), GLN14_ARATH (Q9FMD9), GLN15_ARATH (Q8GXW5), 
GLN1A_BACCE (P19064), GLN1A_BACSU (P12425), GLN1A_CLOSA (P10656), 
GLN1A_LACDE (P45627), GLN1A_LACLA (Q9CDL9), GLN1A_MYCBO (P64246), 
GLN1A_MYCS2 (A0R083), GLN1A_MYCTO (P9WN36), GLN1A_MYCTU (P9WN37), 
GLN1A_STAAC (Q5HGC3), GLN1A_STAAM (P60890), GLN1A_STAAN (P99095), 
GLN1A_STAAR (Q6GHC6), GLN1A_STAAS (Q6G9Q4), GLN1A_STAAU (P0A040), 
GLN1A_STAAW (P0A039), GLN1A_STAEQ (Q5HPN2), GLN1A_STAES (Q8CSR8), 
GLN1A_THEMA (P36205), GLN1B_ACIFR (P07804), GLN1B_AZOBR (P10583), 
GLN1B_AZOC5 (P94126), GLN1B_AZOVI (P22248), GLN1B_BRADU (P05457), 
GLN1B_CERSP (P43518), GLN1B_ECO57 (P0A9C7), GLN1B_ECOL6 (P0A9C6), 
GLN1B_ECOLI (P0A9C5), GLN1B_FRAAL (P46033), GLN1B_HAEIN (P43794), 
GLN1B_HELPJ (Q9ZLW5), GLN1B_HELPY (P94845), GLN1B_METCA (P15124), 
GLN1B_MICDP (P33035), GLN1B_MYCBO (P0A591), GLN1B_MYCS2 (A0R079), 
GLN1B_MYCTO (P9WN38), GLN1B_MYCTU (P9WN39), GLN1B_NEIGO (P25821), 
GLN1B_NOSS1 (P00964), GLN1B_PASMU (Q9CLP2), GLN1B_PICP2 (P28605), 
GLN1B_PROHU (P28786), GLN1B_PSEAE (Q9HU65), GLN1B_PSETA (Q3V5W6), 
GLN1B_RHILV (P09826), GLN1B_RHIME (Q59747), GLN1B_RHOCA (P13499), 
GLN1B_SALTI (P0A1P7), GLN1B_SALTY (P0A1P6), GLN1B_SHIFL (P0A9C8), 
GLN1B_STRCO (P15106), GLN1B_STRFL (P77958), GLN1B_STRVR (Q05542), 
GLN1B_SYNY3 (P77961), GLN1B_TRITH (P51120), GLN1B_VIBAL (P19904), 
GLN1B_VIBCH (Q9KNJ2), GLNA1_ALNGL (O04867), GLNA1_CHLRE (Q42688), 
GLNA1_DAUCA (O22504), GLNA1_DROME (P20477), GLNA1_LOTJA (Q42899), 
GLNA1_MAIZE (P38559), GLNA1_MEDSA (P04078), GLNA1_METMA (Q8PY99), 
GLNA1_PEA   (P08282), GLNA1_PHAVU (P04770), GLNA1_SOYBN (P24099), 
GLNA1_VITVI (P51118), GLNA2_ARATH (Q43127), GLNA2_BRADU (P04772), 
GLNA2_CHLRE (Q42689), GLNA2_DAUCA (O22506), GLNA2_DROME (P20478), 
GLNA2_FRAAL (P20805), GLNA2_HORVU (P13564), GLNA2_MAIZE (P38560), 
GLNA2_MEDSA (Q9XQ94), GLNA2_ORYSJ (P14655), GLNA2_PEA   (P08281), 
GLNA2_PHAVU (P04771), GLNA2_RHILP (Q02154), GLNA2_RHIML (P45626), 
GLNA2_SOYBN (O82560), GLNA2_STRCO (Q9RDS6), GLNA2_STRHY (P22878), 
GLNA2_STRVR (P19432), GLNA2_VITVI (P51119), GLNA3_BACFR (P15623), 
GLNA3_BUTFI (Q05650), GLNA3_DICDI (Q54WR9), GLNA3_HALMT (I3R176), 
GLNA3_HORVU (Q06378), GLNA3_LUPAN (P14636), GLNA3_MAIZE (P38561), 
GLNA3_MEDSA (Q43785), GLNA3_PEA   (P07694), GLNA3_PHAVU (P00965), 
GLNA3_RHILP (P31592), GLNA3_RHIME (O87393), GLNA4_MAIZE (P38562), 
GLNA4_PEA   (Q43066), GLNA4_PHAVU (P15102), GLNA5_MAIZE (P38563), 
GLNAC_BRANA (Q42624), GLNAC_MAIZE (P25462), GLNA_ACOCA  (Q9QY94), 
GLNA_AGABI  (O00088), GLNA_AMAMU  (Q8X169), GLNA_ARCFU  (O29313), 
GLNA_BOVIN  (P15103), GLNA_CANGA  (Q6FMT6), GLNA_CANLF  (Q8HZM5), 
GLNA_CHICK  (P16580), GLNA_COLGL  (Q12613), GLNA_CRIGR  (P04773), 
GLNA_CRYNB  (P0CN85), GLNA_CRYNJ  (P0CN84), GLNA_DEBHA  (Q6B4U7), 
GLNA_DUNSA  (P11600), GLNA_EMENI  (Q96V52), GLNA_EREGS  (Q75BT9), 
GLNA_FUSSH  (Q9UUN6), GLNA_HALSA  (Q9HNI2), GLNA_HALVD  (P43386), 
GLNA_HEBCY  (Q96UV5), GLNA_HUMAN  (P15104), GLNA_KLULA  (Q874T6), 
GLNA_LACSA  (P23712), GLNA_LUPLU  (P52782), GLNA_MACFA  (Q4R7U3), 
GLNA_METJA  (Q60182), GLNA_METMP  (O59648), GLNA_METTH  (O27612), 
GLNA_METVO  (P21154), GLNA_MIMIV  (Q5UR44), GLNA_MOUSE  (P15105), 
GLNA_NEUCR  (Q86ZF9), GLNA_NICPL  (P12424), GLNA_PANAR  (Q04831), 
GLNA_PIG(P46410), GLNA_PINSY  (P52783), GLNA_PYRAB  (Q9UY99), 
GLNA_PYRFU  (Q05907), GLNA_PYRHO  (O58097), GLNA_PYRWO  (P36687), 
GLNA_RAT(P09606), GLNA_SACS2  (P23794), GLNA_SCHPO  (Q09179), 
GLNA_SQUAC  (P41320), GLNA_SUIBO  (Q8J1R3), GLNA_SULAC  (Q9HH09), 
GLNA_THEKO  (O08467), GLNA_THET8  (Q5SIP0), GLNA_TUBBO  (Q86ZU6), 
GLNA_VIGAC  (P32289), GLNA_XENLA  (P51121), GLNA_YARLI  (Q6C3E0), 
GLNA_YEAST  (P32288), GMAS_METMY  (A9ZPH9), GMAS_METUF  (F5RH07), 
PUUA_ECOLI  (P78061)
» more

UniProtKB/Swiss-Prot
False negative sequences		 13 sequences 

GLN1B_AQUAE (O66514), GLNA1_DICDI (Q86B00), GLNA2_DICDI (P0C7B6), 

GLNA2_HALMT (I3R584), GLNA3_STRCO (Q9KZC7), GLNA4_STRCO (O88070), 
GLNA_CAEEL  (P34497), GLNA_FUSFU  (Q9C2U9), LGSN_CANLF  (Q1ZZS1), 
LGSN_HUMAN  (Q5TDP6), LGSN_MOUSE  (Q8CIX8), LGSN_RABIT  (Q0GA40), 
LGSN_RAT(Q7TT51)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

GLN1B_PHOLP (P20479), GLNA2_EMIHU (P81643), GLNA2_PINPS (P81107), 

GLNA_VITSX  (P85087)
» more

PDB
[Detailed view]		 50 PDB

pdb_00001f1h; pdb_00001f52; pdb_00001fpy; pdb_00001hto; pdb_00001htq; pdb_00001lgr; pdb_00002bvc; pdb_00002d3a; pdb_00002d3b; pdb_00002d3c; pdb_00002gls; pdb_00002lgs; pdb_00002ojw; pdb_00002qc8; pdb_00002uu7; pdb_00002wgs; pdb_00002whi; pdb_00003fky; pdb_00003ng0; pdb_00003zxr; pdb_00003zxv; pdb_00004acf; pdb_00004lnf; pdb_00004lni; pdb_00004lnk; pdb_00004lnn; pdb_00004lno; pdb_00004s0r; pdb_00004xyc; pdb_00005ldf; pdb_00005zli; pdb_00005zlp; pdb_00007cpr; pdb_00007evt; pdb_00007u5n; pdb_00007w85; pdb_00008dnu; pdb_00008ecy; pdb_00008fbp; pdb_00008pvg; pdb_00008s59; pdb_00008tfb; pdb_00008tfc; pdb_00008tfk; pdb_00008tge; pdb_00008ufj; pdb_00008v1y; pdb_00008v22; pdb_00008xlj; pdb_00009c28
» more