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PROSITE entry PS00183


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General information about the entry

Entry name [info] UBC_1
Accession [info] PS00183
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00163
Associated ProRule [info] PRU10133

Name and characterization of the entry

Description [info] Ubiquitin-conjugating (UBC) active site signature.
Pattern [info]
[FYWLSP]-H-[PC]-[NHL]-[LIV]-x(3,4)-G-x-[LIVP]-C-[LIV]-x(1,2)-[LIVR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 241 in 241 different sequences
Number of true positive hits 241 in 241 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 81
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 74.84 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 10
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
241 sequences

PEX4_ARATH  (Q8LGF7), RCE1_ARATH  (Q9SDY5), SCE1_ARATH  (Q42551), 
U2D2B_MOUSE (Q6ZWY6), U2D2B_RAT   (P70711), UB12L_ARATH (Q9ZU75), 
UB2D1_BOVIN (Q2TA10), UB2D1_HUMAN (P51668), UB2D1_MOUSE (P61080), 
UB2D1_RAT   (D3ZDK2), UB2D2_BOVIN (Q1RMX2), UB2D2_HUMAN (P62837), 
UB2D2_MOUSE (P62838), UB2D2_PIG   (Q06AA9), UB2D2_RAT   (P62839), 
UB2D2_XENLA (P62840), UB2D3_HUMAN (P61077), UB2D3_MACFA (Q4R5N4), 
UB2D3_MOUSE (P61079), UB2D3_PONAB (Q5R4V7), UB2D3_RAT   (P61078), 
UB2D4_HUMAN (Q9Y2X8), UB2D4_XENLA (A5PKP9), UB2E1_HUMAN (P51965), 
UB2E1_MOUSE (P52482), UB2E2_HUMAN (Q96LR5), UB2E2_MOUSE (Q91W82), 
UB2E3_BOVIN (Q2T9X7), UB2E3_HUMAN (Q969T4), UB2E3_MOUSE (P52483), 
UB2FA_MOUSE (Q9CY34), UB2FB_MOUSE (Q3UWQ3), UB2G1_HUMAN (P62253), 
UB2G1_MACFA (Q4R5Y8), UB2G1_MOUSE (P62254), UB2G1_RAT   (P62255), 
UB2G2_BOVIN (Q17QG5), UB2G2_HUMAN (P60604), UB2G2_MOUSE (P60605), 
UB2G2_PONAB (Q5RF84), UB2L3_BOVIN (Q3MHP1), UB2L3_HUMAN (P68036), 
UB2L3_MOUSE (P68037), UB2L3_PONAB (Q5R5I4), UB2L5_HUMAN (A0A1B0GUS4), 
UB2L6_BOVIN (A5PJC4), UB2L6_HUMAN (O14933), UB2L6_MOUSE (Q9QZU9), 
UB2L6_RAT   (Q4V8J2), UB2R1_HUMAN (P49427), UB2R1_MOUSE (Q8CFI2), 
UB2R2_HUMAN (Q712K3), UB2R2_MOUSE (Q6ZWZ2), UB2R2_RABIT (Q29503), 
UB2SA_XENLA (A1L3K1), UB2SB_XENLA (Q8AVU2), UB2SC_XENLA (Q76EZ2), 
UBC10_ARATH (P35133), UBC10_DROME (Q7K738), UBC11_ARATH (P35134), 
UBC11_SCHPO (O00103), UBC11_YEAST (P52492), UBC12_ARATH (Q9C9Y7), 
UBC12_BOVIN (A3KN22), UBC12_CAEEL (Q9XVK5), UBC12_CANGA (Q6FVQ8), 
UBC12_DICDI (Q54TI6), UBC12_EREGS (Q75AF2), UBC12_HUMAN (P61081), 
UBC12_KLULA (Q6CSW8), UBC12_MOUSE (P61082), UBC12_SCHPO (O74549), 
UBC12_XENLA (Q6DCZ9), UBC12_XENTR (Q6P8D9), UBC12_YARLI (Q6C9W0), 
UBC12_YEAST (P52491), UBC13_ARATH (Q42541), UBC13_CAEEL (Q95XX0), 
UBC13_SCHPO (O13685), UBC13_YEAST (P52490), UBC14_ARATH (P42747), 
UBC15_ARATH (P42743), UBC15_SCHPO (Q9Y818), UBC16_ARATH (Q9FWT2), 
UBC17_ARATH (O23239), UBC18_ARATH (Q9FMM0), UBC19_ARATH (Q9LJZ5), 
UBC1_ARATH  (P25865), UBC1_CAEEL  (P52478), UBC1_COLGL  (O74196), 
UBC1_PYRO7  (Q9UVR2), UBC1_SCHPO  (O74810), UBC1_YEAST  (P21734), 
UBC20_ARATH (Q8L7T3), UBC21_CAEEL (P52484), UBC22_ARATH (Q9FF66), 
UBC27_ARATH (Q9FI61), UBC28_ARATH (Q94F47), UBC29_ARATH (Q9SLE4), 
UBC2M_DROME (Q9VSF3), UBC2_ARATH  (P42745), UBC2_ASPFU  (Q4WLA7), 
UBC2_CAEEL  (P35129), UBC2_CANAL  (O74201), UBC2_CANGA  (Q6FR76), 
UBC2_CRYNB  (P0CS17), UBC2_CRYNJ  (P0CS16), UBC2_DEBHA  (Q6BU36), 
UBC2_DICDI  (Q553F3), UBC2_EMENI  (Q96UP5), UBC2_EREGS  (Q75EB8), 
UBC2_FUSSL  (P78717), UBC2_KLULA  (Q6CUD9), UBC2_MEDSA  (P35130), 
UBC2_NEUCR  (P52493), UBC2_SCHPO  (P23566), UBC2_TRIHA  (Q58FS2), 
UBC2_USTMA  (Q4PFA5), UBC2_WHEAT  (P25866), UBC2_YARLI  (Q6C093), 
UBC2_YEAST  (P06104), UBC30_ARATH (Q9FKT3), UBC35_ARATH (Q94A97), 
UBC36_ARATH (Q9FZ48), UBC37_ARATH (Q941B6), UBC3_ARATH  (P42746), 
UBC3_YEAST  (P14682), UBC4_ARATH  (P42748), UBC4_CANAX  (P43102), 
UBC4_SCHPO  (P46595), UBC4_SOLLC  (P35135), UBC4_WHEAT  (P16577), 
UBC4_YEAST  (P15731), UBC5A_ORYSJ (Q8S920), UBC5B_ORYSJ (Q8S919), 
UBC5_ARATH  (P42749), UBC5_YEAST  (P15732), UBC6_ARATH  (P42750), 
UBC7_ARATH  (Q42540), UBC7_CAEEL  (P34477), UBC7_SCHPO  (O00102), 
UBC7_WHEAT  (P25868), UBC7_YEAST  (Q02159), UBC84_DROME (P52487), 
UBC8_ARATH  (P35131), UBC8_SCHPO  (Q9P7R4), UBC8_YEAST  (P28263), 
UBC9A_DANRE (Q9W6H5), UBC9B_DANRE (Q9DDJ0), UBC9_ARATH  (P35132), 
UBC9_CAEEL  (Q95017), UBC9_CHICK  (P63283), UBC9_DICDI  (Q9NGP4), 
UBC9_HUMAN  (P63279), UBC9_ICTTR  (Q2EF73), UBC9_MESAU  (O09181), 
UBC9_MOUSE  (P63280), UBC9_PAGMA  (Q6Y1Z4), UBC9_RAT(P63281), 
UBC9_SCHPO  (P40984), UBC9_XENLA  (P63282), UBC9_XENTR  (Q28CQ4), 
UBC9_YEAST  (P50623), UBCD1_DROME (P25867), UBCD2_DROME (P52485), 
UBCD4_DROME (P52486), UBCD6_DROME (P25153), UBCX_DICDI  (Q86IZ3), 
UBCX_PICAN  (O60015), UBCX_PICPA  (P49428), UBCX_YEAST  (P29340), 
UBC_ASFB7   (P27949), UBC_ASFK5   (P0C8G3), UBC_ASFM2   (P25869), 
UBC_ASFP4   (P0C8G4), UBC_ASFWA   (P0C8G5), UBE2A_HUMAN (P49459), 
UBE2A_MOUSE (Q9Z255), UBE2B_BOVIN (Q32P99), UBE2B_HUMAN (P63146), 
UBE2B_MOUSE (P63147), UBE2B_RABIT (P63148), UBE2B_RAT   (P63149), 
UBE2C_BOVIN (Q32PA5), UBE2C_DICDI (Q54XS6), UBE2C_DROME (Q9VTY6), 
UBE2C_HUMAN (O00762), UBE2C_MACFA (Q4R9D1), UBE2C_MOUSE (Q9D1C1), 
UBE2C_SPISO (Q95044), UBE2C_XENLA (P56616), UBE2F_BOVIN (Q1RMW1), 
UBE2F_CHICK (Q5ZKX6), UBE2F_DANRE (Q6NY82), UBE2F_HUMAN (Q969M7), 
UBE2F_RAT   (Q5U203), UBE2F_XENLA (Q6IRC7), UBE2F_XENTR (Q5M8Y2), 
UBE2H_BOVIN (Q32LN1), UBE2H_HUMAN (P62256), UBE2H_MOUSE (P62257), 
UBE2K_BOVIN (P61085), UBE2K_HUMAN (P61086), UBE2K_MOUSE (P61087), 
UBE2N_BOVIN (Q0P5K3), UBE2N_DICDI (Q86K32), UBE2N_DROME (P35128), 
UBE2N_HUMAN (P61088), UBE2N_MACFA (Q4R4I1), UBE2N_MOUSE (P61089), 
UBE2N_PONAB (Q5R7J6), UBE2N_RAT   (Q9EQX9), UBE2S_AQUCT (C1C3R6), 
UBE2S_BOVIN (Q1RML1), UBE2S_BRAFL (C3Z724), UBE2S_DANRE (Q4V908), 
UBE2S_DICDI (Q54I43), UBE2S_DROAN (B3MQV3), UBE2S_DROER (B3NWW9), 
UBE2S_DROGR (B4JKB7), UBE2S_DROME (Q9VX25), UBE2S_DROMO (B4L7V4), 
UBE2S_DROPE (B4H9W2), UBE2S_DROPS (B5DKM4), UBE2S_DROSE (B4IF39), 
UBE2S_DROSI (B4R6G1), UBE2S_DROVI (B4MA02), UBE2S_DROWI (B4N208), 
UBE2S_DROYA (B4Q2J2), UBE2S_HUMAN (Q16763), UBE2S_MOUSE (Q921J4), 
UBE2S_NEMVE (A7SE05), UBE2S_RAT   (B5DFI8), UBE2S_XENTR (Q28F89), 
UBE2T_BOVIN (Q32LD2), UBE2T_DANRE (Q08BH7), UBE2T_HUMAN (Q9NPD8), 
UBE2T_MOUSE (Q9CQ37), UBE2T_XENLA (Q7ZY08), UBE2U_HUMAN (Q5VVX9), 
UBE2U_MACFA (Q95LM1)
» more

UniProtKB/Swiss-Prot
False negative sequences
81 sequences

BIRC6_HUMAN (Q9NR09), BIRC6_MOUSE (O88738), COP10_ARATH (Q9LJD7), 
MMS2_SCHPO  (O74983), MMS2_YEAST  (P53152), U2D2L_HUMAN (Q8IWF7), 
U2QL1_DROME (Q9VM35), U2QL1_HUMAN (A1L167), U2QL1_MOUSE (A0PJN4), 
UB2J1_HUMAN (Q9Y385), UB2J1_MOUSE (Q9JJZ4), UB2J2_BOVIN (Q2TA03), 
UB2J2_DICDI (Q54LP7), UB2J2_HUMAN (Q8N2K1), UB2J2_MOUSE (Q6P073), 
UB2JL_DICDI (Q54AK6), UB2Q1_HUMAN (Q7Z7E8), UB2Q1_MOUSE (Q7TSS2), 
UB2Q2_BOVIN (Q32L27), UB2Q2_HUMAN (Q8WVN8), UB2Q2_MOUSE (Q8K2Z8), 
UB2Q2_RABIT (Q7YQJ9), UB2V1_BOVIN (Q3SZ52), UB2V1_CHICK (Q90879), 
UB2V1_HUMAN (Q13404), UB2V1_MOUSE (Q9CZY3), UB2V1_PONAB (Q5R4Z6), 
UB2V2_BOVIN (Q3SZ43), UB2V2_CHICK (Q5F3Z3), UB2V2_DANRE (Q6PEH5), 
UB2V2_HUMAN (Q15819), UB2V2_MOUSE (Q9D2M8), UB2V2_PONAB (Q5R6C9), 
UB2V2_RAT   (Q7M767), UB2V2_XENLA (Q7ZYP0), UB2WA_DANRE (Q4VBH4), 
UBC14_SCHPO (Q9UTN8), UBC16_SCHPO (Q9P6I1), UBC17_CAEEL (Q11076), 
UBC18_CAEEL (Q21633), UBC1_MIMIV  (Q5UQC9), UBC23_ARATH (Q9ZVX1), 
UBC24_ARATH (Q8VY10), UBC25_ARATH (Q9LUQ5), UBC25_CAEEL (Q93571), 
UBC26_ARATH (Q8GY87), UBC31_ARATH (Q9C8X7), UBC32_ARATH (Q9LSP7), 
UBC33_ARATH (Q9FK29), UBC34_ARATH (Q9SHI7), UBC38_ARATH (Q9C918), 
UBC39_ARATH (F4HPP7), UBC3_MIMIV  (Q5UQ88), UBC4_MIMIV  (Q5UQ40), 
UBC6_CANGA  (Q6FQK7), UBC6_DEBHA  (Q6BYG4), UBC6_EREGS  (Q74Z34), 
UBC6_KLULA  (Q6CMG6), UBC6_SCHPO  (O42646), UBC6_YEAST  (P33296), 
UBCB_DICDI  (Q94490), UBE2O_HUMAN (Q9C0C9), UBE2O_MOUSE (Q6ZPJ3), 
UBE2V_DICDI (Q54D06), UBE2W_BOVIN (A6H795), UBE2W_CAEEL (Q9XWF6), 
UBE2W_HUMAN (Q96B02), UBE2W_MOUSE (Q8VDW4), UBE2W_RAT   (B5DEI4), 
UBE2Z_DANRE (Q6DG60), UBE2Z_HUMAN (Q9H832), UBE2Z_MOUSE (Q3UE37), 
UBE2Z_RAT   (Q3B7D1), UBE2Z_XENLA (Q6PCF7), UBE2Z_XENTR (Q66KB0), 
UE2NL_HUMAN (Q5JXB2), UEV1A_ARATH (Q93YP0), UEV1B_ARATH (Q9CAB6), 
UEV1C_ARATH (Q9SJ44), UEV1D_ARATH (Q9SVD7), Y1A1_ENCCU  (Q8SSK3)
» more

PDB
[Detailed view]
256 PDB

1A3S; 1AYZ; 1C4Z; 1FBV; 1FXT; 1FZY; 1J7D; 1JAS; 1JAT; 1JBB; 1KPS; 1PZV; 1Q34; 1QCQ; 1TTE; 1U9A; 1U9B; 1UR6; 1W4U; 1WZV; 1WZW; 1X23; 1Y6L; 1Y8X; 1YH2; 1YLA; 1YRV; 1Z2U; 1Z3D; 1Z5S; 1ZDN; 2AAK; 2AWF; 2BEP; 2BF8; 2C2V; 2C4P; 2CLW; 2CYX; 2E2C; 2EDI; 2EKE; 2ESK; 2ESO; 2ESP; 2ESQ; 2FUH; 2GJD; 2GRN; 2GRP; 2GRQ; 2GRR; 2KJH; 2KLY; 2LXP; 2O25; 2OB4; 2PE6; 2PX9; 2UCZ; 2VRR; 2XWU; 2Y4W; 2Y9M; 2Y9P; 2YB6; 2YBF; 2YHO; 2Z5D; 3A4S; 3BZH; 3E46; 3EB6; 3F92; 3FN1; 3FSH; 3H8K; 3HCT; 3HCU; 3K9O; 3K9P; 3L1Y; 3L1Z; 3O2U; 3OJ4; 3ONG; 3PTF; 3RCZ; 3RPG; 3RZ3; 3SQV; 3SY2; 3TGD; 3UIN; 3UIO; 3UIP; 3VON; 3W31; 4A49; 4A4B; 4A4C; 4CCG; 4DHI; 4DHJ; 4DHZ; 4II2; 4IP3; 4JQU; 4LAD; 4MDK; 4NR3; 4NRG; 4NRI; 4ONL; 4ONM; 4ONN; 4ORH; 4Q5E; 4Q5H; 4QPL; 4R8P; 4S3O; 4TKP; 4W5V; 4X57; 4Y1L; 4YII; 5A31; 5AIE; 5BNB; 5D1K; 5D1L; 5D1M; 5D2M; 5EGG; 5F6D; 5F6E; 5F6U; 5F6V; 5F6W; 5F6X; 5F6Y; 5FQ2; 5HPT; 5IFR; 5JNE; 5KHR; 5KNL; 5L9T; 5L9U; 5LBN; 5NGZ; 5NKZ; 5NL8; 5OJJ; 5OJW; 5YWR; 6CYO; 6CYR; 6D4P; 6D68; 6D6I; 6FGA; 6GUM; 6GV3; 6IF1; 6JKY; 6KFP; 6KG6; 6KL4; 6LP2; 6M2C; 6NYA; 6NYD; 6OP8; 6P5B; 6Q83; 6QH3; 6QHK; 6R75; 6S96; 6S98; 6SYF; 6T7F; 6TTU; 6ULH; 6UMP; 6UMS; 6W7Z; 6W9A; 6XOD; 6XXU; 6ZHS; 6ZHT; 6ZHU; 7AHF; 7B5L; 7B5N; 7BOL; 7BXG; 7K5J; 7KZR; 7KZS; 7KZT; 7KZV; 7LEW; 7LYB; 7M2K; 7MEX; 7MEY; 7MYH; 7OIK; 7P47; 7UV8; 7UVC; 7V8F; 7W75; 7W76; 8B3I; 8GRM; 8GRQ; 8IEG; 8IEJ; 8IYA; 8JVE; 8JVL; 8ODR; 8OIF; 8PQL; 8Q7R; 8R5H; 8SE9; 8SEA; 8SEB; 8SMW; 8SMX; 8SMY; 8SMZ; 8SN0; 8SN1; 8SN2; 8SN3; 8SN4; 8SN5; 8SN6; 8SN7; 8SN8; 8SN9; 8SNA; 8SV8; 8TAR; 8TAU; 8U14; 8UPF; 8UQ8; 8UQ9
» more