PROSITE entry PS00183
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PURL: https://purl.expasy.org/prosite/signature/PS00183
Direct ScanProsite submission
General information about the entry
| Entry name [info] | UBC_1 |
| Accession [info] | PS00183 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00163 |
| Associated ProRule [info] | PRU10133 |
Name and characterization of the entry
| Description [info] | Ubiquitin-conjugating (UBC) active site signature. |
| Pattern [info] |
[FYWLSP]-H-[PC]-[NHL]-[LIV]-x(3,4)-G-x-[LIVP]-C-[LIV]-x(1,2)-[LIVR]. |
Numerical results [info]
| Total number of hits | 242 in 242 different sequences |
| Number of true positive hits | 242 in 242 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 81 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 74.92 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 10 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
242 sequences
PEX4_ARATH (Q8LGF7), PEX4_KOMPG (C4R826), PEX4_PICPA (P49428), RCE1_ARATH (Q9SDY5), SCE1_ARATH (Q42551), U2D2B_MOUSE (Q6ZWY6), U2D2B_RAT (P70711), UB12L_ARATH (Q9ZU75), UB2D1_BOVIN (Q2TA10), UB2D1_HUMAN (P51668), UB2D1_MOUSE (P61080), UB2D1_RAT (D3ZDK2), UB2D2_BOVIN (Q1RMX2), UB2D2_HUMAN (P62837), UB2D2_MOUSE (P62838), UB2D2_PIG (Q06AA9), UB2D2_RAT (P62839), UB2D2_XENLA (P62840), UB2D3_HUMAN (P61077), UB2D3_MACFA (Q4R5N4), UB2D3_MOUSE (P61079), UB2D3_PONAB (Q5R4V7), UB2D3_RAT (P61078), UB2D4_HUMAN (Q9Y2X8), UB2D4_XENLA (A5PKP9), UB2E1_HUMAN (P51965), UB2E1_MOUSE (P52482), UB2E2_HUMAN (Q96LR5), UB2E2_MOUSE (Q91W82), UB2E3_BOVIN (Q2T9X7), UB2E3_HUMAN (Q969T4), UB2E3_MOUSE (P52483), UB2FA_MOUSE (Q9CY34), UB2FB_MOUSE (Q3UWQ3), UB2G1_HUMAN (P62253), UB2G1_MACFA (Q4R5Y8), UB2G1_MOUSE (P62254), UB2G1_RAT (P62255), UB2G2_BOVIN (Q17QG5), UB2G2_HUMAN (P60604), UB2G2_MOUSE (P60605), UB2G2_PONAB (Q5RF84), UB2L3_BOVIN (Q3MHP1), UB2L3_HUMAN (P68036), UB2L3_MOUSE (P68037), UB2L3_PONAB (Q5R5I4), UB2L5_HUMAN (A0A1B0GUS4), UB2L6_BOVIN (A5PJC4), UB2L6_HUMAN (O14933), UB2L6_MOUSE (Q9QZU9), UB2L6_RAT (Q4V8J2), UB2R1_HUMAN (P49427), UB2R1_MOUSE (Q8CFI2), UB2R2_HUMAN (Q712K3), UB2R2_MOUSE (Q6ZWZ2), UB2R2_RABIT (Q29503), UB2SA_XENLA (A1L3K1), UB2SB_XENLA (Q8AVU2), UB2SC_XENLA (Q76EZ2), UBC10_ARATH (P35133), UBC10_DROME (Q7K738), UBC11_ARATH (P35134), UBC11_SCHPO (O00103), UBC11_YEAST (P52492), UBC12_ARATH (Q9C9Y7), UBC12_BOVIN (A3KN22), UBC12_CAEEL (Q9XVK5), UBC12_CANGA (Q6FVQ8), UBC12_DICDI (Q54TI6), UBC12_EREGS (Q75AF2), UBC12_HUMAN (P61081), UBC12_KLULA (Q6CSW8), UBC12_MOUSE (P61082), UBC12_SCHPO (O74549), UBC12_XENLA (Q6DCZ9), UBC12_XENTR (Q6P8D9), UBC12_YARLI (Q6C9W0), UBC12_YEAST (P52491), UBC13_ARATH (Q42541), UBC13_CAEEL (Q95XX0), UBC13_SCHPO (O13685), UBC13_YEAST (P52490), UBC14_ARATH (P42747), UBC15_ARATH (P42743), UBC15_SCHPO (Q9Y818), UBC16_ARATH (Q9FWT2), UBC17_ARATH (O23239), UBC18_ARATH (Q9FMM0), UBC19_ARATH (Q9LJZ5), UBC1_ARATH (P25865), UBC1_CAEEL (P52478), UBC1_COLGL (O74196), UBC1_PYRO7 (Q9UVR2), UBC1_SCHPO (O74810), UBC1_YEAST (P21734), UBC20_ARATH (Q8L7T3), UBC21_CAEEL (P52484), UBC22_ARATH (Q9FF66), UBC27_ARATH (Q9FI61), UBC28_ARATH (Q94F47), UBC29_ARATH (Q9SLE4), UBC2M_DROME (Q9VSF3), UBC2_ARATH (P42745), UBC2_ASPFU (Q4WLA7), UBC2_CAEEL (P35129), UBC2_CANAL (O74201), UBC2_CANGA (Q6FR76), UBC2_CRYNB (P0CS17), UBC2_CRYNJ (P0CS16), UBC2_DEBHA (Q6BU36), UBC2_DICDI (Q553F3), UBC2_EMENI (Q96UP5), UBC2_EREGS (Q75EB8), UBC2_FUSSL (P78717), UBC2_KLULA (Q6CUD9), UBC2_MEDSA (P35130), UBC2_MYCMD (Q4PFA5), UBC2_NEUCR (P52493), UBC2_SCHPO (P23566), UBC2_TRIHA (Q58FS2), UBC2_WHEAT (P25866), UBC2_YARLI (Q6C093), UBC2_YEAST (P06104), UBC30_ARATH (Q9FKT3), UBC35_ARATH (Q94A97), UBC36_ARATH (Q9FZ48), UBC37_ARATH (Q941B6), UBC3_ARATH (P42746), UBC3_YEAST (P14682), UBC4_ARATH (P42748), UBC4_CANAX (P43102), UBC4_SCHPO (P46595), UBC4_SOLLC (P35135), UBC4_WHEAT (P16577), UBC4_YEAST (P15731), UBC5A_ORYSJ (Q8S920), UBC5B_ORYSJ (Q8S919), UBC5_ARATH (P42749), UBC5_YEAST (P15732), UBC6_ARATH (P42750), UBC7_ARATH (Q42540), UBC7_CAEEL (P34477), UBC7_SCHPO (O00102), UBC7_WHEAT (P25868), UBC7_YEAST (Q02159), UBC84_DROME (P52487), UBC8_ARATH (P35131), UBC8_SCHPO (Q9P7R4), UBC8_YEAST (P28263), UBC9A_DANRE (Q9W6H5), UBC9B_DANRE (Q9DDJ0), UBC9_ARATH (P35132), UBC9_CAEEL (Q95017), UBC9_CHICK (P63283), UBC9_DICDI (Q9NGP4), UBC9_HUMAN (P63279), UBC9_ICTTR (Q2EF73), UBC9_MESAU (O09181), UBC9_MOUSE (P63280), UBC9_PAGMA (Q6Y1Z4), UBC9_RAT(P63281), UBC9_SCHPO (P40984), UBC9_XENLA (P63282), UBC9_XENTR (Q28CQ4), UBC9_YEAST (P50623), UBCD1_DROME (P25867), UBCD2_DROME (P52485), UBCD4_DROME (P52486), UBCD6_DROME (P25153), UBCX_DICDI (Q86IZ3), UBCX_PICAN (O60015), UBCX_YEAST (P29340), UBC_ASFB7 (P27949), UBC_ASFK5 (P0C8G3), UBC_ASFM2 (P25869), UBC_ASFP4 (P0C8G4), UBC_ASFWA (P0C8G5), UBE2A_HUMAN (P49459), UBE2A_MOUSE (Q9Z255), UBE2B_BOVIN (Q32P99), UBE2B_HUMAN (P63146), UBE2B_MOUSE (P63147), UBE2B_RABIT (P63148), UBE2B_RAT (P63149), UBE2C_BOVIN (Q32PA5), UBE2C_DICDI (Q54XS6), UBE2C_DROME (Q9VTY6), UBE2C_HUMAN (O00762), UBE2C_MACFA (Q4R9D1), UBE2C_MOUSE (Q9D1C1), UBE2C_SPISO (Q95044), UBE2C_XENLA (P56616), UBE2F_BOVIN (Q1RMW1), UBE2F_CHICK (Q5ZKX6), UBE2F_DANRE (Q6NY82), UBE2F_HUMAN (Q969M7), UBE2F_RAT (Q5U203), UBE2F_XENLA (Q6IRC7), UBE2F_XENTR (Q5M8Y2), UBE2H_BOVIN (Q32LN1), UBE2H_HUMAN (P62256), UBE2H_MOUSE (P62257), UBE2K_BOVIN (P61085), UBE2K_HUMAN (P61086), UBE2K_MOUSE (P61087), UBE2N_BOVIN (Q0P5K3), UBE2N_DICDI (Q86K32), UBE2N_DROME (P35128), UBE2N_HUMAN (P61088), UBE2N_MACFA (Q4R4I1), UBE2N_MOUSE (P61089), UBE2N_PONAB (Q5R7J6), UBE2N_RAT (Q9EQX9), UBE2S_AQUCT (C1C3R6), UBE2S_BOVIN (Q1RML1), UBE2S_BRAFL (C3Z724), UBE2S_DANRE (Q4V908), UBE2S_DICDI (Q54I43), UBE2S_DROAN (B3MQV3), UBE2S_DROER (B3NWW9), UBE2S_DROGR (B4JKB7), UBE2S_DROME (Q9VX25), UBE2S_DROMO (B4L7V4), UBE2S_DROPE (B4H9W2), UBE2S_DROPS (B5DKM4), UBE2S_DROSE (B4IF39), UBE2S_DROSI (B4R6G1), UBE2S_DROVI (B4MA02), UBE2S_DROWI (B4N208), UBE2S_DROYA (B4Q2J2), UBE2S_HUMAN (Q16763), UBE2S_MOUSE (Q921J4), UBE2S_NEMVE (A7SE05), UBE2S_RAT (B5DFI8), UBE2S_XENTR (Q28F89), UBE2T_BOVIN (Q32LD2), UBE2T_DANRE (Q08BH7), UBE2T_HUMAN (Q9NPD8), UBE2T_MOUSE (Q9CQ37), UBE2T_XENLA (Q7ZY08), UBE2U_HUMAN (Q5VVX9), UBE2U_MACFA (Q95LM1)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
81 sequences
BIRC6_HUMAN (Q9NR09), BIRC6_MOUSE (O88738), COP10_ARATH (Q9LJD7), MMS2_SCHPO (O74983), MMS2_YEAST (P53152), U2D2L_HUMAN (Q8IWF7), U2QL1_DROME (Q9VM35), U2QL1_HUMAN (A1L167), U2QL1_MOUSE (A0PJN4), UB2J1_HUMAN (Q9Y385), UB2J1_MOUSE (Q9JJZ4), UB2J2_BOVIN (Q2TA03), UB2J2_DICDI (Q54LP7), UB2J2_HUMAN (Q8N2K1), UB2J2_MOUSE (Q6P073), UB2JL_DICDI (Q54AK6), UB2Q1_HUMAN (Q7Z7E8), UB2Q1_MOUSE (Q7TSS2), UB2Q2_BOVIN (Q32L27), UB2Q2_HUMAN (Q8WVN8), UB2Q2_MOUSE (Q8K2Z8), UB2Q2_RABIT (Q7YQJ9), UB2V1_BOVIN (Q3SZ52), UB2V1_CHICK (Q90879), UB2V1_HUMAN (Q13404), UB2V1_MOUSE (Q9CZY3), UB2V1_PONAB (Q5R4Z6), UB2V2_BOVIN (Q3SZ43), UB2V2_CHICK (Q5F3Z3), UB2V2_DANRE (Q6PEH5), UB2V2_HUMAN (Q15819), UB2V2_MOUSE (Q9D2M8), UB2V2_PONAB (Q5R6C9), UB2V2_RAT (Q7M767), UB2V2_XENLA (Q7ZYP0), UB2WA_DANRE (Q4VBH4), UBC14_SCHPO (Q9UTN8), UBC16_SCHPO (Q9P6I1), UBC17_CAEEL (Q11076), UBC18_CAEEL (Q21633), UBC1_MIMIV (Q5UQC9), UBC23_ARATH (Q9ZVX1), UBC24_ARATH (Q8VY10), UBC25_ARATH (Q9LUQ5), UBC25_CAEEL (Q93571), UBC26_ARATH (Q8GY87), UBC31_ARATH (Q9C8X7), UBC32_ARATH (Q9LSP7), UBC33_ARATH (Q9FK29), UBC34_ARATH (Q9SHI7), UBC38_ARATH (Q9C918), UBC39_ARATH (F4HPP7), UBC3_MIMIV (Q5UQ88), UBC4_MIMIV (Q5UQ40), UBC6_CANGA (Q6FQK7), UBC6_DEBHA (Q6BYG4), UBC6_EREGS (Q74Z34), UBC6_KLULA (Q6CMG6), UBC6_SCHPO (O42646), UBC6_YEAST (P33296), UBCB_DICDI (Q94490), UBE2O_HUMAN (Q9C0C9), UBE2O_MOUSE (Q6ZPJ3), UBE2V_DICDI (Q54D06), UBE2W_BOVIN (A6H795), UBE2W_CAEEL (Q9XWF6), UBE2W_HUMAN (Q96B02), UBE2W_MOUSE (Q8VDW4), UBE2W_RAT (B5DEI4), UBE2Z_DANRE (Q6DG60), UBE2Z_HUMAN (Q9H832), UBE2Z_MOUSE (Q3UE37), UBE2Z_RAT (Q3B7D1), UBE2Z_XENLA (Q6PCF7), UBE2Z_XENTR (Q66KB0), UE2NL_HUMAN (Q5JXB2), UEV1A_ARATH (Q93YP0), UEV1B_ARATH (Q9CAB6), UEV1C_ARATH (Q9SJ44), UEV1D_ARATH (Q9SVD7), Y1A1_ENCCU (Q8SSK3)» more |
| PDB [Detailed view] |
299 PDB
1A3S; 1AYZ; 1C4Z; 1FBV; 1FXT; 1FZY; 1J7D; 1JAS; 1JAT; 1JBB; 1KPS; 1PZV; 1Q34; 1QCQ; 1TTE; 1U9A; 1U9B; 1UR6; 1W4U; 1WZV; 1WZW; 1X23; 1Y6L; 1Y8X; 1YH2; 1YLA; 1YRV; 1Z2U; 1Z3D; 1Z5S; 1ZDN; 2AAK; 2AWF; 2BEP; 2BF8; 2C2V; 2C4P; 2CLW; 2CYX; 2E2C; 2EDI; 2EKE; 2ESK; 2ESO; 2ESP; 2ESQ; 2FUH; 2GJD; 2GRN; 2GRP; 2GRQ; 2GRR; 2KJH; 2KLY; 2LXP; 2O25; 2OB4; 2PE6; 2PX9; 2UCZ; 2VRR; 2XWU; 2Y4W; 2Y9M; 2Y9P; 2YB6; 2YBF; 2YHO; 2Z5D; 3A4S; 3BZH; 3E46; 3EB6; 3F92; 3FN1; 3FSH; 3H8K; 3HCT; 3HCU; 3K9O; 3K9P; 3L1Y; 3L1Z; 3O2U; 3OJ4; 3ONG; 3PTF; 3RCZ; 3RPG; 3RZ3; 3SQV; 3SY2; 3TGD; 3UIN; 3UIO; 3UIP; 3VON; 3W31; 4A49; 4A4B; 4A4C; 4CCG; 4DHI; 4DHJ; 4DHZ; 4II2; 4IP3; 4JQU; 4LAD; 4MDK; 4NR3; 4NRG; 4NRI; 4ONL; 4ONM; 4ONN; 4ORH; 4Q5E; 4Q5H; 4QPL; 4R8P; 4S3O; 4TKP; 4W5V; 4X57; 4Y1L; 4YII; 5A31; 5AIE; 5BNB; 5D1K; 5D1L; 5D1M; 5D2M; 5EGG; 5F6D; 5F6E; 5F6U; 5F6V; 5F6W; 5F6X; 5F6Y; 5FQ2; 5HPT; 5IFR; 5JNE; 5KHR; 5KNL; 5L9T; 5L9U; 5LBN; 5NGZ; 5NKZ; 5NL8; 5OJJ; 5OJW; 5YWR; 6CYO; 6CYR; 6D4P; 6D68; 6D6I; 6FGA; 6GUM; 6GV3; 6IF1; 6JKY; 6KFP; 6KG6; 6KL4; 6LP2; 6M2C; 6NYA; 6NYD; 6OP8; 6P5B; 6Q83; 6QH3; 6QHK; 6R75; 6S96; 6S98; 6SYF; 6T7F; 6TTU; 6ULH; 6UMP; 6UMS; 6W7Z; 6W9A; 6XOD; 6XXU; 6ZHS; 6ZHT; 6ZHU; 7AHF; 7B5L; 7B5N; 7BOL; 7BXG; 7K5J; 7KZR; 7KZS; 7KZT; 7KZV; 7LEW; 7LYB; 7M2K; 7MEX; 7MEY; 7MYH; 7OIK; 7P47; 7UV8; 7UVC; 7V8F; 7W75; 7W76; 8B3I; 8GRM; 8GRQ; 8IEG; 8IEJ; 8IYA; 8J1R; 8JUC; 8JVD; 8JVE; 8JVL; 8ODR; 8OIF; 8PQL; 8Q7R; 8R5H; 8RX0; 8SE9; 8SEA; 8SEB; 8SMW; 8SMX; 8SMY; 8SMZ; 8SN0; 8SN1; 8SN2; 8SN3; 8SN4; 8SN5; 8SN6; 8SN7; 8SN8; 8SN9; 8SNA; 8SV8; 8TAR; 8TAU; 8U14; 8UPF; 8UQ8; 8UQ9; 8V0D; 8VK8; 8VK9; 8X7I; 8X7J; 8X7K; 9B55; 9B56; 9B57; 9B58; 9B59; 9B5A; 9B5B; 9B5C; 9B5D; 9B5E; 9B5F; 9B5G; 9B5H; 9B5I; 9B5J; 9B5K; 9B5L; 9B5M; 9B5N; 9B5O; 9B5P; 9B5Q; 9B5R; 9B5S; 9B5T; 9B5U; 9B5V; 9B5W; 9B5X; 9B62; 9BIV; 9IPU; 9JTC » more |