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PROSITE entry PS00185


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PURL: https://purl.expasy.org/prosite/signature/PS00185

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General information about the entry

Entry name [info] IPNS_1
Accession [info] PS00185
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00165

Name and characterization of the entry

Description [info] Isopenicillin N synthase signature 1.
Pattern [info] 
[RK]-x-[STA]-x(2)-S-x-C-Y-[SL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 22 in 22 different sequences
Number of true positive hits 13 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 59.09 %
Recall (true positives / (true positives + false negatives)) 86.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 13 sequences 

EXPA_HAPCH  (P11935), IPNA_EMENI  (P05326), IPNA_HAPCH  (P05189), 

IPNA_PENCH  (P08703), IPNA_PENRW  (B6HLU0), IPNS_AMYLA  (P27744), 
IPNS_FLASS  (P16020), IPNS_LYSLA  (Q48739), IPNS_STRCL  (P10621), 
IPNS_STRCT  (Q53932), IPNS_STRGR  (Q54243), IPNS_STRJU  (P18286), 
IPNS_STRMI  (P12438)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

CEFE_AMYLA  (Q03047), CEFE_STRCL  (P18548)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			9 sequences
			


			
ALG3_DROVI  (Q24332), HYAS1_HUMAN (Q92839), HYAS1_MOUSE (Q61647), 

			
LUC8_FUSSX  (A0A6J4B484), PMIP_MALGO  (A8QB25), RIR1_CHLMU  (Q9PL93), 
RIR1_CHLPN  (Q9Z6S5), RIR1_CHLTR  (O84834), ZHP2_CAEEL  (Q9U3L0)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			84 PDB
			


			pdb_00001bk0; pdb_00001blz; pdb_00001hb1; pdb_00001hb2; pdb_00001hb3; pdb_00001hb4; pdb_00001ips; pdb_00001obn; pdb_00001oc1; pdb_00001odm; pdb_00001odn; pdb_00001qiq; 
			
				pdb_00001qje; pdb_00001qjf; pdb_00001uzw; pdb_00001w03; pdb_00001w04; pdb_00001w05; pdb_00001w06; pdb_00001w3v; pdb_00001w3x; pdb_00002bjs; pdb_00002bu9; pdb_00002ivi; 
				pdb_00002ivj; pdb_00002jb4; pdb_00002vau; pdb_00002vbb; pdb_00002vbd; pdb_00002vbp; pdb_00002vcm; pdb_00002ve1; pdb_00002wo7; pdb_00002y60; pdb_00002y6f; pdb_00003zku; 
				pdb_00003zky; pdb_00003zoi; pdb_00004bb3; pdb_00006y0o; pdb_00006y0p; pdb_00006zae; pdb_00006zaf; pdb_00006zag; pdb_00006zah; pdb_00006zai; pdb_00006zaj; pdb_00006zak; 
				pdb_00006zal; pdb_00006zam; pdb_00006zan; pdb_00006zao; pdb_00006zap; pdb_00006zaq; pdb_00006zw8; pdb_00007p3l; pdb_00007poy; pdb_00007psw; pdb_00007zoe; pdb_00008a4g; 
				pdb_00008ali; pdb_00008alj; pdb_00008bb9; pdb_00008bba; pdb_00008bbb; pdb_00008bbc; pdb_00008bbd; pdb_00008bsv; pdb_00008bsw; pdb_00008bsx; pdb_00008bsy; pdb_00008p46; 
				pdb_00008p47; pdb_00008p48; pdb_00008p7o; pdb_00008p7p; pdb_00008ptv; pdb_00008py5; pdb_00008py6; pdb_00008py7; pdb_00008py8; pdb_00008py9; pdb_00008pya; pdb_00008rdb
			
			

			» more