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PROSITE entry PS00186


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00186
Entry name [info] IPNS_2
Accession [info] PS00186
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-1990 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00165

Name and characterization of the entry

Description [info] Isopenicillin N synthase signature 2.
Pattern [info] 
[LIVM](2)-x-C-G-[STA]-x(2)-[STAG]-x(2)-T-x-[DNG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 17 in 17 different sequences
Number of true positive hits 13 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 4 in 4 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 76.47 %
Recall (true positives / (true positives + false negatives)) 86.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 13 sequences 

CEFE_STRCL  (P18548), EXPA_HAPCH  (P11935), IPNA_EMENI  (P05326), 

IPNA_HAPCH  (P05189), IPNA_PENCH  (P08703), IPNA_PENRW  (B6HLU0), 
IPNS_FLASS  (P16020), IPNS_LYSLA  (Q48739), IPNS_STRCL  (P10621), 
IPNS_STRCT  (Q53932), IPNS_STRGR  (Q54243), IPNS_STRJU  (P18286), 
IPNS_STRMI  (P12438)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

CEFE_AMYLA  (Q03047), IPNS_AMYLA  (P27744)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			4 sequences
			


			
PGRP1_BOSIN (B5T255), PGRP1_BOVIN (Q8SPP7), Y3471_BRADU (Q89PK9), 

			
Y4391_ARATH (Q9T020)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			101 PDB
			


			1BK0; 1BLZ; 1DCS; 1E5H; 1E5I; 1HB1; 1HB2; 1HB3; 1HB4; 1HJF; 1HJG; 1IPS; 
			
				1OBN; 1OC1; 1ODM; 1ODN; 1QIQ; 1QJE; 1QJF; 1RXF; 1RXG; 1UNB; 1UO9; 1UOB; 
				1UOF; 1UOG; 1UZW; 1W03; 1W04; 1W05; 1W06; 1W28; 1W2A; 1W2N; 1W2O; 1W3V; 
				1W3X; 2BJS; 2BU9; 2IVI; 2IVJ; 2JB4; 2JB8; 2VAU; 2VBB; 2VBD; 2VBP; 2VCM; 
				2VE1; 2WO7; 2Y60; 2Y6F; 3ZKU; 3ZKY; 3ZOI; 4BB3; 6Y0O; 6Y0P; 6ZAE; 6ZAF; 
				6ZAG; 6ZAH; 6ZAI; 6ZAJ; 6ZAK; 6ZAL; 6ZAM; 6ZAN; 6ZAO; 6ZAP; 6ZAQ; 6ZW8; 
				7P3L; 7POY; 7PSW; 7ZOE; 8A4G; 8ALI; 8ALJ; 8BB9; 8BBA; 8BBB; 8BBC; 8BBD; 
				8BSV; 8BSW; 8BSX; 8BSY; 8P46; 8P47; 8P48; 8P7O; 8P7P; 8PTV; 8PY5; 8PY6; 
				8PY7; 8PY8; 8PY9; 8PYA; 8RDB
			
			

			» more