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PROSITE entry PS00188


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PURL: https://purl.expasy.org/prosite/signature/PS00188

Direct ScanProsite submission
General information about the entry

Entry name [info] BIOTIN
Accession [info] PS00188
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00167

Name and characterization of the entry

Description [info] Biotin-requiring enzymes attachment site.
Pattern [info] 
[GDN]-[DEQTR]-x-[LIVMFY]-x(2)-[LIVM]-x-[AIV]-M-K-[LVMAT]-x(3)-[LIVM]-x-
[SAV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 81 in 81 different sequences
Number of true positive hits 81 in 81 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 13
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.17 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] biotin at position 10
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 81 sequences 

2OCL_HYDTT  (D3DJ41), ACACA_BOVIN (Q9TTS3), ACACA_HUMAN (Q13085), 

ACACA_MOUSE (Q5SWU9), ACACA_RAT   (P11497), ACACA_SHEEP (Q28559), 
ACAC_CHICK  (P11029), ACAC_DICDI  (Q54J08), ACAC_SCHPO  (P78820), 
ACAC_YEAST  (Q00955), ACC1_ARATH  (Q38970), ACC2_ARATH  (F4I1L3), 
ACCA1_MYCBO (P0A509), ACCA1_MYCTO (P9WPQ2), ACCA1_MYCTU (P9WPQ3), 
ACCA3_MYCLE (P46392), ACCA3_MYCTU (P96890), BCCP1_ARATH (Q42533), 
BCCP2_ARATH (Q9LLC1), BCCP_BACSU  (P49786), BCCP_CHLMU  (Q9PKR5), 
BCCP_CHLPN  (Q9Z901), BCCP_CHLTR  (O84125), BCCP_CYACA  (O19918), 
BCCP_ECO57  (P0ABE0), BCCP_ECOL6  (P0ABD9), BCCP_ECOLI  (P0ABD8), 
BCCP_HAEIN  (P43874), BCCP_NOSS1  (Q06881), BCCP_PORPU  (P51283), 
BCCP_PROFR  (P02904), BCCP_PSEAE  (P37799), BCCP_PYRYE  (Q1XDK5), 
BCCP_SHIFL  (P0ABE1), BCCP_SOLLC  (P05115), BCCP_SOYBN  (Q42783), 
BCCP_STRMU  (P29337), BCCP_STRP6  (Q5XAE6), DCOA_KLEPN  (P13187), 
DCOA_SALTI  (Q8XGX8), DCOA_SALTY  (Q03030), DMXL1_CRYX8 (A0A4P8DJE6), 
DUR1_LACKL  (A5H0J2), DUR1_YEAST  (P32528), GCDC_ACIFV  (Q9ZAA7), 
HFA1_YEAS1  (B3LM95), HFA1_YEAS2  (C7GRE4), HFA1_YEAS7  (A6ZMR9), 
HFA1_YEAS8  (C8ZF72), HFA1_YEAST  (P32874), LAMA_EMENI  (P38095), 
MCCA_ARATH  (Q42523), MCCA_DICDI  (Q54KE6), MCCA_HUMAN  (Q96RQ3), 
MCCA_MOUSE  (Q99MR8), MCCA_ORYSJ  (Q2QMG2), MCCA_RAT(Q5I0C3), 
MCCA_SOYBN  (Q42777), MMDC_PROMO  (O54030), MMDC_VEIPA  (Q57111), 
PCCA_CAEBR  (Q612F5), PCCA_CAEEL  (Q19842), PCCA_HALMT  (I3R7G3), 
PCCA_HUMAN  (P05165), PCCA_MOUSE  (Q91ZA3), PCCA_PIG(P0DTA4), 
PCCA_RAT(P14882), PCCA_RUEPO  (Q5LUF3), PYC1_YEAST  (P11154), 
PYC2_YEAST  (P32327), PYCB_METJA  (Q58628), PYC_ASPNG   (Q9HES8), 
PYC_ASPTE   (O93918), PYC_ASPTN   (Q0CLK1), PYC_BOVIN   (Q29RK2), 
PYC_HUMAN   (P11498), PYC_MOUSE   (Q05920), PYC_PICAN   (Q8X1T3), 
PYC_PICPA   (P78992), PYC_RAT (P52873), PYC_SCHPO   (Q9UUE1)
» more

UniProtKB/Swiss-Prot
False negative sequences		 13 sequences 

ACACB_HUMAN (O00763), ACC1_ORYSJ  (Q8S6N5), ACC2_ORYSJ  (B9FK36), 

BLAP_BACSU  (C0H419), BTB7_MYCBO  (P0A511), BTB7_MYCLE  (Q9CCH9), 
BTB7_MYCS2  (Q9XCD6), BTB7_MYCTO  (P9WPQ0), BTB7_MYCTU  (P9WPQ1), 
MADF_MALRU  (O06930), PYC1_CAEEL  (O17732), PYCB_METTH  (O27179), 
PYC_BACSU   (Q9KWU4)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PCCA_MYXXA  (P81185)


				
	

	

		PDB
[Detailed view]		
		
			51 PDB
			


			pdb_00001a6x; pdb_00001bdo; pdb_00001dcz; pdb_00001dd2; pdb_00001o78; pdb_00002bdo; pdb_00002ejm; pdb_00002jku; pdb_00003bdo; pdb_00003bg3; pdb_00003bg9; pdb_00003n6r; 
			
				pdb_00004hr7; pdb_00005csa; pdb_00005csk; pdb_00005csl; pdb_00005mlk; pdb_00006g2d; pdb_00006g2h; pdb_00006g2i; pdb_00006roj; pdb_00007wta; pdb_00007wtb; pdb_00007wtc; 
				pdb_00007wtd; pdb_00007wte; pdb_00007ybu; pdb_00008hwl; pdb_00008j4z; pdb_00008j78; pdb_00008j7d; pdb_00008j7o; pdb_00008j99; pdb_00008jak; pdb_00008jaw; pdb_00008jxl; 
				pdb_00008jxm; pdb_00008jxn; pdb_00008k2v; pdb_00008uz2; pdb_00008xkz; pdb_00008xl0; pdb_00008xl1; pdb_00008xl2; pdb_00008xl3; pdb_00008xl4; pdb_00008xl5; pdb_00008xl6; 
				pdb_00008xl7; pdb_00008xl8; pdb_00008xl9
			
			

			» more