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PROSITE entry PS00203


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PURL: https://purl.expasy.org/prosite/signature/PS00203

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General information about the entry

Entry name [info] METALLOTHIONEIN_VRT
Accession [info] PS00203
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00180

Name and characterization of the entry

Description [info] Vertebrate metallothioneins signature.
Pattern [info] 
C-x-C-[GSTAP]-x(2)-C-x-C-x(2)-C-x-C-x(2)-C-x-K.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 118 in 118 different sequences
Number of true positive hits 118 in 118 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 7
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 94.40 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] metal at position 1
Site [info] metal at position 3
Site [info] metal at position 6
Site [info] metal at position 8
Site [info] metal at position 10
Site [info] metal at position 12
Site [info] metal at position 14
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 118 sequences 

MT1A_BOVIN  (P67983), MT1A_HORSE  (P02800), MT1A_HUMAN  (P04731), 

MT1A_PIG(P49068), MT1A_RABIT  (P11957), MT1A_SHEEP  (P67982), 
MT1B_HORSE  (P02801), MT1B_HUMAN  (P07438), MT1B_SHEEP  (P09577), 
MT1C_PIG(P79376), MT1C_SHEEP  (P09578), MT1D_PIG(P79377), 
MT1E_HUMAN  (P04732), MT1E_PIG(P79431), MT1F_HUMAN  (P04733), 
MT1F_PIG(P79378), MT1G_HUMAN  (P13640), MT1H_BOVIN  (P55942), 
MT1H_HUMAN  (P80294), MT1L_HUMAN  (Q93083), MT1M_HUMAN  (Q8N339), 
MT1X_HUMAN  (P80297), MT1_BOVIN   (P58280), MT1_CANLF   (O19000), 
MT1_CHLAE   (P02797), MT1_COLLI   (P15786), MT1_CRIGR   (P02804), 
MT1_CYPCA   (O13269), MT1_DANRE   (P52722), MT1_MOUSE   (P02802), 
MT1_RAT (P02803), MT2A_RABIT  (P18055), MT2B_PIG(P79380), 
MT2B_RABIT  (P80289), MT2C_RABIT  (P80290), MT2D_RABIT  (P80291), 
MT2E_RABIT  (P80292), MT2H_BOVIN  (P55943), MT2_BOVIN   (P68301), 
MT2_CANLF   (Q9XST5), MT2_CHLAE   (P68304), MT2_COLLI   (P15787), 
MT2_CRIGR   (P67981), MT2_CRILO   (P68041), MT2_CYPCA   (Q9I9I0), 
MT2_DANRE   (Q7ZSY6), MT2_HUMAN   (P02795), MT2_MACFA   (P68303), 
MT2_MESAU   (P17808), MT2_MOUSE   (P02798), MT2_PIG (P79379), 
MT2_PONAB   (Q5NVS0), MT2_RAT (P04355), MT2_SHEEP   (P68302), 
MT2_STECO   (P14425), MT3_HORSE   (P37360), MT3_HUMAN   (P25713), 
MT3_MACFA   (Q2PFZ0), MT3_MOUSE   (P28184), MT3_PIG (P55944), 
MT3_RAT (P37361), MT4_CANLF   (Q9TUI5), MT4_MOUSE   (P47945), 
MTA_CARCW   (Q8AWG2), MTA_CHAAC   (O93593), MTA_CHIHA   (P68506), 
MTA_CHIRA   (P62338), MTA_CYPS1   (Q92044), MTA_GYMAC   (P68507), 
MTA_NOTNE   (P62339), MTA_ONCMY   (P68503), MTA_PAGBO   (P68508), 
MTA_PARCR   (O93450), MTA_SALAL   (P68505), MTA_SALSA   (P68504), 
MTA_SPAAU   (P52727), MTA_THECR   (P52721), MTA_TREBE   (O93609), 
MTB_CARCW   (Q8AWG1), MTB_CHAAC   (P52724), MTB_CHIHA   (P62711), 
MTB_CHIRA   (P62679), MTB_DICLA   (Q9PTG9), MTB_GYMAC   (P62713), 
MTB_MORSA   (P62712), MTB_NOTNE   (P62680), MTB_ONCMY   (P68501), 
MTB_PAGBO   (P62681), MTB_PARCR   (P62682), MTB_SALAL   (P68502), 
MTB_SALSA   (P52720), MTB_TREBE   (P62678), MT_AMBME(O42152), 
MT_ANAPL(P68494), MT_BALMY(O18842), MT_BARBB(P25128), 
MT_CAIMO(P68495), MT_CARAU(P52723), MT_CHEAU(O13257), 
MT_CHICK(P68497), MT_ESOLU(P25127), MT_GADMO(P51902), 
MT_GOBCO(Q800D3), MT_ICTPU(O93571), MT_LITMO(Q8UVY1), 
MT_MELGA(P68498), MT_OREAU(Q7ZZP9), MT_OREMO(P52726), 
MT_ORYLA(Q6S4N8), MT_PAGMA(Q9IB50), MT_PERFL(P52725), 
MT_PLEAT(Q6XUW5), MT_PLEPL(P07216), MT_PODSI(Q708T3), 
MT_PSEAM(P55945), MT_RUTRU(P80593), MT_XENLA(Q05890), 
MT_ZOAVI(P52728)
» more

UniProtKB/Swiss-Prot
False negative sequences		 7 sequences 

M1BL1_HUMAN (P0DM35), MT3_BOSMU   (Q2MJS5), MT3_BOVIN   (P37359), 

MT3_RABIT   (Q2PS21), MT3_SHEEP   (Q8MKE4), MT4_HUMAN   (P47944), 
MT_SCYTO(Q6J1T3)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 3 sequences 

MTA_COLVI   (P27086), MTB_COLVI   (P27087), MT_PHACO(P68499)


				
	

	

		PDB
[Detailed view]		
		
			1 PDB
			


			pdb_00004mt2