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PROSITE entry PS00214


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00214
Entry name [info] FABP
Accession [info] PS00214
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00188

Name and characterization of the entry

Description [info] Cytosolic fatty-acid binding proteins signature.
Pattern [info] 
[GSAIVK]-{FE}-[FYW]-x-[LIVMF]-x(2)-{K}-x-[NHG]-[FY]-[DE]-x-[LIVMFY]-
[LIVM]-{N}-{G}-[LIVMAKR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 141 in 141 different sequences
Number of true positive hits 112 in 112 different sequences
Number of 'unknown' hits 1
Number of false positive hits 28 in 28 different sequences
Number of false negative sequences 14
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 80.00 %
Recall (true positives / (true positives + false negatives)) 88.89 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 112 sequences 

FA10A_DANRE (Q9I8L5), FAB1A_DANRE (Q1AMT3), FABH_ASCSU  (P55776), 

FABP1_AMBME (P81399), FABP1_CAEEL (Q20223), FABP1_DORPE (C4N147), 
FABP1_ECHGR (Q02970), FABP1_MANSE (P31416), FABP2_AMBME (P81400), 
FABP2_CAEEL (Q20224), FABP2_ECHGR (Q9BMK3), FABP2_MANSE (P31417), 
FABP3_CAEEL (Q20222), FABP4_BOVIN (P48035), FABP4_CAEEL (Q23092), 
FABP4_CEREL (A6YLM6), FABP4_HUMAN (P15090), FABP4_ICTTR (Q99P60), 
FABP4_MOUSE (P04117), FABP4_PIG   (O97788), FABP4_PYGPA (A0A0K0MJN3), 
FABP4_RAT   (P70623), FABP5_BOVIN (P55052), FABP5_CAEEL (O01814), 
FABP5_HUMAN (Q01469), FABP5_MOUSE (Q05816), FABP5_PYGPA (A0A0K0MJ13), 
FABP5_RAT   (P55053), FABP6_CAEEL (O01812), FABP6_HUMAN (P51161), 
FABP6_MOUSE (P51162), FABP6_PIG   (P10289), FABP6_RABIT (P50119), 
FABP6_RAT   (P80020), FABP7_BOVIN (Q09139), FABP7_CAEEL (O02323), 
FABP7_CHICK (Q05423), FABP7_HUMAN (O15540), FABP7_MOUSE (P51880), 
FABP7_RAT   (P55051), FABP8_CAEEL (O02324), FABP9_CAEEL (Q965W1), 
FABP9_HUMAN (Q0Z7S8), FABP9_MOUSE (O08716), FABP9_RAT   (P55054), 
FABPH_BOSMU (Q4TZH2), FABPH_BOVIN (P10790), FABPH_HUMAN (P05413), 
FABPH_ICTTR (Q99P61), FABPH_MOUSE (P11404), FABPH_MYOLU (Q865F7), 
FABPH_ONCMY (O13008), FABPH_PIG   (O02772), FABPH_RAT   (P07483), 
FABPI_BOVIN (Q56JX9), FABPI_HUMAN (P12104), FABPI_MOUSE (P55050), 
FABPI_PIG   (Q45KW7), FABPI_RAT   (P02693), FABPI_XENLA (Q91775), 
FABPL_ANOPU (Q90239), FABPL_AQUCT (P0C241), FABPL_BOVIN (P80425), 
FABPL_CHICK (P80226), FABPL_GINCI (P80049), FABPL_HUMAN (P07148), 
FABPL_LEPPA (P82289), FABPL_MOUSE (P12710), FABPL_PIG   (P49924), 
FABPL_RAT   (P02692), FABPL_RHASA (P80856), FABPL_RHIAE (P83409), 
FABPM_LOCMI (P41509), FABPM_SCHGR (P41496), FABP_ACASI  (O76821), 
FABP_ANOGA  (Q17017), FABP_BLOTA  (Q17284), FABP_CLOSI  (Q8MUC1), 
FABP_LEPDS  (Q9U5P1), FABP_SCHJA  (O45035), FABP_SCHMA  (P29498), 
FABP_TYRPU  (Q66RP5), MYP2_BOVIN  (P02690), MYP2_HORSE  (P0C6G6), 
MYP2_HUMAN  (P02689), MYP2_MOUSE  (P24526), MYP2_PIG(P86412), 
MYP2_RABIT  (P02691), RABP1_BOVIN (P62964), RABP1_CHICK (P40220), 
RABP1_HIPCM (Q6T499), RABP1_HUMAN (P29762), RABP1_MOUSE (P62965), 
RABP1_PELSI (Q5R2J5), RABP1_RAT   (P62966), RABP1_TAKRU (O42386), 
RABP2_BOVIN (Q5PXY7), RABP2_CHICK (P30370), RABP2_HUMAN (P29373), 
RABP2_MOUSE (P22935), RABP2_RAT   (P51673), RABP2_XENLA (P50568), 
RET1_BOVIN  (P02694), RET1_HUMAN  (P09455), RET1_MOUSE  (Q00915), 
RET1_RAT(P02696), RET2_HUMAN  (P50120), RET2_MOUSE  (Q08652), 
RET2_PIG(P50121), RET2_RAT(P06768), RET7_HUMAN  (Q96R05), 
RET7_MOUSE  (Q9EPC5)
» more

UniProtKB/Swiss-Prot
False negative sequences		 14 sequences 

FABP1_FASGI (Q9UAS2), FABP1_FASHE (Q7M4G0), FABP2_FASHE (Q7M4G1), 

FABP3_FASHE (Q9U1G6), FABPL_CHAVI (P82145), FABPL_SCHBI (P81653), 
FBP12_HUMAN (A6NFH5), FBP12_MOUSE (Q9DAK4), FBP12_RAT   (B7SUM8), 
IOTA_GONVI  (P82025), RET5_BOVIN  (P82708), RET5_HUMAN  (P82980), 
RET5_PONAB  (Q5RBM7), UNAG_ANGJA  (P0DM59)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

FABPI_RHASA (P81175), FABPL_LETCA (P82188)


				
	

	

		UniProtKB/Swiss-Prot
'Unknown' sequences		
		
			1 sequence
			


			
VPS13_CHATD (G0S3B8)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			28 sequences
			


			
DPOL_METJA  (Q58295), FB278_ARATH (Q9FFS9), GLPG_PECAS  (Q6CZL3), 

			
LPTD_FRAT1  (Q14IY9), LPTD_FRATH  (Q2A216), LPTD_FRATN  (A0Q5D8), 
LPTD_FRATO  (Q0BKP5), LPTD_FRATT  (Q5NHI7), MFNA_PYRFU  (Q8U1P6), 
MFNA_PYRHO  (O58679), MRAZ_RICPR  (Q9ZCY1), MRAZ_RICTY  (Q68WG6), 
MUT7_CAEEL  (P34607), ORR12_ORYSJ (Q2HWG1), ORR13_ORYSJ (Q2HWG0), 
PYRG_NITHX  (Q1QMJ4), PYRG_RHOP2  (Q2IWB8), PYRG_RICBR  (Q1RHU4), 
PYRG_RICCN  (Q92I97), PYRG_RICFE  (Q4ULX9), PYRG_RICPR  (Q9ZDF1), 
PYRG_RICTY  (Q68WZ6), RRAGC_HUMAN (Q9HB90), RRAGC_MOUSE (Q99K70), 
SYFB_MESFL  (Q6F166), SYR_METHJ   (Q2FS66), TSN36_DANRE (Q6NWG0), 
ZWILC_CAEEL (Q95XP9)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			684 PDB
			


			1A18; 1A2D; 1AB0; 1ACD; 1ADL; 1AEL; 1ALB; 1B4M; 1B56; 1BLR; 1BM5; 1BWY; 
			
				1CBI; 1CBQ; 1CBR; 1CBS; 1CRB; 1DC9; 1EAL; 1EII; 1EIO; 1FDQ; 1FE3; 1FTP; 
				1G5W; 1G74; 1G7N; 1HMR; 1HMS; 1HMT; 1ICM; 1ICN; 1IFB; 1IFC; 1JBH; 1JJJ; 
				1JJX; 1KGL; 1KZW; 1KZX; 1LFO; 1LIB; 1LIC; 1LID; 1LIE; 1LIF; 1LPJ; 1MDC; 
				1MVG; 1MX7; 1MX8; 1O1U; 1O1V; 1O8V; 1OPA; 1OPB; 1P6P; 1PMP; 1T8V; 1TOU; 
				1TOW; 1TVQ; 1TW4; 1URE; 1VYF; 1VYG; 1XCA; 1YIV; 1ZRY; 2ANS; 2CBR; 2CBS; 
				2F73; 2FLJ; 2FR3; 2FS6; 2FS7; 2FT9; 2FTB; 2G78; 2G79; 2G7B; 2HMB; 2HNX; 
				2IFB; 2JN3; 2JU3; 2JU7; 2JU8; 2K62; 2L67; 2L68; 2LFO; 2LKK; 2MJI; 2MM3; 
				2MO5; 2NNQ; 2POA; 2PY1; 2Q9S; 2QM9; 2QO4; 2QO5; 2QO6; 2RCQ; 2RCT; 2WUT; 
				3AKM; 3AKN; 3B2H; 3B2I; 3B2J; 3B2K; 3B2L; 3CBS; 3CR6; 3CWK; 3D95; 3D96; 
				3D97; 3F8A; 3F9D; 3FA6; 3FA7; 3FA8; 3FA9; 3FEK; 3FEL; 3FEN; 3FEP; 3FR2; 
				3FR4; 3FR5; 3HK1; 3I17; 3IFB; 3JS1; 3JSQ; 3NR3; 3P6C; 3P6D; 3P6E; 3P6F; 
				3P6G; 3P6H; 3PP6; 3PPT; 3Q6L; 3RSW; 3RZY; 3STK; 3STM; 3STN; 3VG2; 3VG3; 
				3VG4; 3VG5; 3VG6; 3VG7; 3WBG; 3WVM; 3WXQ; 4A1H; 4A1Y; 4A60; 4A8Z; 4AZM; 
				4AZN; 4AZO; 4AZP; 4AZQ; 4AZR; 4BVM; 4D6A; 4D6B; 4EXZ; 4I9R; 4I9S; 4LKP; 
				4LKT; 4M6S; 4M7M; 4NNS; 4NNT; 4QGV; 4QGW; 4QGX; 4QYN; 4QYP; 4QZT; 4QZU; 
				4RUU; 4TJZ; 4TKB; 4TKH; 4TKJ; 4WBK; 4YBP; 4YBU; 4YCE; 4YCH; 4YDA; 4YDB; 
				4YFP; 4YFQ; 4YFR; 4YGG; 4YGH; 4YGZ; 4YH0; 4YKM; 4YKO; 4ZCB; 4ZGU; 4ZH6; 
				4ZH9; 4ZJ0; 4ZR2; 5BVQ; 5BVS; 5BVT; 5C0N; 5CE4; 5D45; 5D47; 5D48; 5D4A; 
				5D8J; 5DG4; 5DPQ; 5EDB; 5EDC; 5F58; 5FAZ; 5FEN; 5H8T; 5H9A; 5HA1; 5HBS; 
				5HZ5; 5HZ6; 5HZ8; 5HZ9; 5HZQ; 5L8I; 5L8N; 5L8O; 5LJB; 5LJC; 5LJD; 5LJE; 
				5LJG; 5LJH; 5LJK; 5N4M; 5N4P; 5N4Q; 5OGB; 5U6G; 5UR9; 5URA; 5Y0F; 5Y0G; 
				5Y0X; 5Y12; 5Y13; 6AQ1; 6AT8; 6AYL; 6BTH; 6BTI; 6C1Z; 6C7Z; 6DO6; 6DO7; 
				6DRG; 6E50; 6E51; 6E5E; 6E5L; 6E5Q; 6E5R; 6E5S; 6E5T; 6E6K; 6E6L; 6E6M; 
				6E7M; 6EW2; 6EW4; 6EW5; 6HKR; 6I8X; 6I9F; 6L7K; 6L9O; 6LJS; 6LJT; 6LJU; 
				6LJV; 6LJW; 6LJX; 6MCU; 6MCV; 6MKV; 6MLB; 6MOP; 6MOQ; 6MOR; 6MOV; 6MOW; 
				6MOX; 6MP4; 6MPK; 6MQI; 6MQJ; 6MQW; 6MQX; 6MQY; 6MQZ; 6MR0; 6NNX; 6NNY; 
				6NOE; 6ON5; 6ON7; 6ON8; 6S2M; 6S2S; 6STS; 6VID; 6VIS; 6VIT; 6WNF; 6WNJ; 
				6WP0; 6WP1; 6WP2; 6XU5; 6XU9; 6XUA; 6XUW; 6XVQ; 6XVR; 6XVS; 6XVY; 6XW9; 
				6Z2U; 6Z2Z; 6ZSW; 6ZSX; 7A9Y; 7A9Z; 7AA0; 7AA1; 7DZE; 7DZF; 7DZG; 7DZH; 
				7DZI; 7DZJ; 7DZK; 7DZL; 7E25; 7EGO; 7EUV; 7EUW; 7FBF; 7FBM; 7FBN; 7FC4; 
				7FCG; 7FCX; 7FD7; 7FDT; 7FDU; 7FDX; 7FEK; 7FEU; 7FEZ; 7FF6; 7FFK; 7FFX; 
				7FG1; 7FG5; 7FVU; 7FVV; 7FVW; 7FVX; 7FVY; 7FVZ; 7FW0; 7FW1; 7FW2; 7FW3; 
				7FW4; 7FW5; 7FW6; 7FW7; 7FW8; 7FW9; 7FWA; 7FWB; 7FWC; 7FWD; 7FWE; 7FWF; 
				7FWG; 7FWH; 7FWI; 7FWJ; 7FWK; 7FWL; 7FWM; 7FWN; 7FWO; 7FWP; 7FWQ; 7FWR; 
				7FWS; 7FWT; 7FWU; 7FWV; 7FWW; 7FWX; 7FWY; 7FWZ; 7FX0; 7FX1; 7FX2; 7FX3; 
				7FX4; 7FX5; 7FX6; 7FX7; 7FX8; 7FX9; 7FXA; 7FXB; 7FXC; 7FXD; 7FXE; 7FXF; 
				7FXG; 7FXH; 7FXI; 7FXJ; 7FXK; 7FXL; 7FXM; 7FXN; 7FXO; 7FXP; 7FXQ; 7FXR; 
				7FXS; 7FXT; 7FXU; 7FXV; 7FXW; 7FXX; 7FXY; 7FXZ; 7FY0; 7FY1; 7FY2; 7FY3; 
				7FY4; 7FY5; 7FY6; 7FY7; 7FY8; 7FY9; 7FYA; 7FYB; 7FYC; 7FYD; 7FYE; 7FYF; 
				7FYG; 7FYH; 7FYI; 7FYJ; 7FYK; 7FYL; 7FYM; 7FYO; 7FYP; 7FYQ; 7FYR; 7FYS; 
				7FYT; 7FYU; 7FYV; 7FYW; 7FYX; 7FYY; 7FYZ; 7FZ0; 7FZ1; 7FZ2; 7FZ3; 7FZ4; 
				7FZ5; 7FZ6; 7FZ7; 7FZ8; 7FZ9; 7FZA; 7FZB; 7FZC; 7FZD; 7FZE; 7FZF; 7FZG; 
				7FZH; 7FZI; 7FZJ; 7FZK; 7FZL; 7FZM; 7FZN; 7FZO; 7FZP; 7FZQ; 7FZR; 7FZS; 
				7FZT; 7FZU; 7FZV; 7FZW; 7FZX; 7FZY; 7FZZ; 7G00; 7G01; 7G02; 7G03; 7G04; 
				7G05; 7G06; 7G07; 7G08; 7G09; 7G0A; 7G0B; 7G0C; 7G0E; 7G0F; 7G0G; 7G0H; 
				7G0I; 7G0J; 7G0K; 7G0L; 7G0M; 7G0N; 7G0O; 7G0P; 7G0Q; 7G0R; 7G0S; 7G0T; 
				7G0U; 7G0V; 7G0W; 7G0X; 7G0Y; 7G0Z; 7G10; 7G11; 7G12; 7G13; 7G14; 7G15; 
				7G16; 7G17; 7G18; 7G19; 7G1A; 7G1B; 7G1C; 7G1D; 7G1E; 7G1F; 7G1G; 7G1H; 
				7G1I; 7G1J; 7G1K; 7G1L; 7G1M; 7G1N; 7G1O; 7G1P; 7G1Q; 7G1R; 7G1S; 7G1T; 
				7G1U; 7G1V; 7G1W; 7G1X; 7G1Y; 7G1Z; 7G20; 7G21; 7JVG; 7JVY; 7JWD; 7JWR; 
				7JX2; 7JZ5; 7K3I; 7MFX; 7MFZ; 7NRW; 7NSR; 7NTP; 7O0J; 7O0K; 7O60; 7OXW; 
				7OXX; 7RY5; 7U8T; 7UCN; 7UCS; 7UCT; 7UCV; 7UCZ; 7UD1; 7UD3; 7V2G; 7V5U; 
				7VB1; 7WC3; 7WCI; 7WD6; 7WDJ; 7WE5; 7WF0; 7WJ1; 7WKB; 7WKG; 7WOM; 7WPG; 
				7WPU; 7WPW; 7WQ7; 7X48; 7X4J; 7X50; 7XBC; 7XHM; 7XHU; 7YF1; 8D6H; 8D6L; 
				8D6N; 8DB2; 8DN1; 8GD2; 8GDM; 8GEM; 8GEU; 8GEV; 8GEW; 8GEY; 8IVF; 8IVL; 
				8S1K; 8VZX; 8VZY; 8W02; 8WDX; 8WE3; 8WKH; 9ETC; 9ETD; 9ETE; 9ETF; 9ETG
			
			

			» more