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PROSITE entry PS00221


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General information about the entry

Entry name [info] MIP
Accession [info] PS00221
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00193

Name and characterization of the entry

Description [info] MIP family signature.
Pattern [info] 
[HNQA]-{D}-N-P-[STA]-[LIVMF]-[ST]-[LIVMF]-[GSTAFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 285 in 285 different sequences
Number of true positive hits 264 in 264 different sequences
Number of 'unknown' hits 0
Number of false positive hits 21 in 21 different sequences
Number of false negative sequences 44
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 92.63 %
Recall (true positives / (true positives + false negatives)) 85.71 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 264 sequences 

AQP10_HUMAN (Q96PS8    ), AQP10_MILTA (G5CTG7    ), AQP1_BOVIN  (P47865    ), 

AQP1_CANLF  (Q9N2J4    ), AQP1_HUMAN  (P29972    ), AQP1_MOUSE  (Q02013    ), 
AQP1_PIG    (Q6PQZ1    ), AQP1_PONAB  (Q5R819    ), AQP1_RAT    (P29975    ), 
AQP1_RHIO9  (I1CR68    ), AQP1_SHEEP  (P56401    ), AQP2_AMBHO  (O77697    ), 
AQP2_BOVIN  (P79099    ), AQP2_CANLF  (P79144    ), AQP2_DASNO  (P79164    ), 
AQP2_DUGDU  (O77714    ), AQP2_ELEMA  (P79168    ), AQP2_ERIEU  (O77722    ), 
AQP2_GIBZE  (I1RHJ1    ), AQP2_HORSE  (P79165    ), AQP2_HUMAN  (P41181    ), 
AQP2_LACBS  (B0D4K0    ), AQP2_MACPR  (P79803    ), AQP2_MOUSE  (P56402    ), 
AQP2_ORYAF  (P79200    ), AQP2_PROHA  (P79229    ), AQP2_RABIT  (P79213    ), 
AQP2_RAT    (P34080    ), AQP2_RHIIR  (I3W9F7    ), AQP2_RHIO9  (I1CS06    ), 
AQP2_SHEEP  (O62735    ), AQP2_TALEU  (O77740    ), AQP3_BOVIN  (Q08DE6    ), 
AQP3_HUMAN  (Q92482    ), AQP3_MOUSE  (Q8R2N1    ), AQP3_PIG    (A9Y006    ), 
AQP3_RAT    (P47862    ), AQP4_BOVIN  (O77750    ), AQP4_DIPME  (Q923J4    ), 
AQP4_GIBZE  (I1RIY3    ), AQP4_HUMAN  (P55087    ), AQP4_MOUSE  (P55088    ), 
AQP4_NOTAL  (Q5I4F9    ), AQP4_RAT    (P47863    ), AQP5_HUMAN  (P55064    ), 
AQP5_LACBI  (I1Z8E7    ), AQP5_LACBS  (B0D4E4    ), AQP5_MILTA  (G5CTG2    ), 
AQP5_MOUSE  (Q9WTY4    ), AQP5_PIG    (A8W649    ), AQP5_RAT    (P47864    ), 
AQP5_SHEEP  (Q866S3    ), AQP6_HUMAN  (Q13520    ), AQP6_LACBI  (I1Z8E8    ), 
AQP6_LACBS  (B0DLE4    ), AQP6_MOUSE  (Q8C4A0    ), AQP6_RAT    (Q9WTY0    ), 
AQP71_LACBI (I1Z8E9    ), AQP72_LACBI (I1Z8F0    ), AQP7_LACBS  (B0D4J9    ), 
AQP7_MILTA  (G5CTG4    ), AQP8_BOTFB  (A0A384JP03), AQP8_HUMAN  (O94778    ), 
AQP8_MOUSE  (P56404    ), AQP8_NOTAL  (Q5I4F8    ), AQP8_RAT    (P56405    ), 
AQP9_BOTFB  (A0A384JSZ0), AQP9_HUMAN  (O43315    ), AQP9_MOUSE  (Q9JJJ3    ), 
AQP9_RAT    (P56627    ), AQPA_DICDI  (Q9U8P7    ), AQPA_PELLE  (P50501    ), 
AQPB_DICDI  (Q54WT8    ), AQPC_DICDI  (Q54V53    ), AQPM_ARCFU  (O28846    ), 
AQPM_METTH  (O26206    ), AQPM_METTM  (Q9C4Z5    ), AQPZ1_AGRFC (Q8UI24    ), 
AQPZ1_RHIME (Q92NM3    ), AQPZ2_AGRFC (Q8UJW4    ), AQPZ2_RHIME (Q92ZW9    ), 
AQPZ_BORBR  (Q7WKG2    ), AQPZ_BORPA  (Q7W917    ), AQPZ_BRADU  (Q89EG9    ), 
AQPZ_BRUA2  (Q2YR68    ), AQPZ_BRUAB  (P0C112    ), AQPZ_BRUME  (Q9L772    ), 
AQPZ_BRUSU  (Q8FY85    ), AQPZ_CHRVO  (Q7NU39    ), AQPZ_ECO57  (Q8X6K6    ), 
AQPZ_ECOL6  (P60845    ), AQPZ_ECOLI  (P60844    ), AQPZ_FLAJO  (Q7WVD3    ), 
AQPZ_GLOVI  (Q7NNP3    ), AQPZ_PHOLL  (Q7N5C1    ), AQPZ_PSEAE  (Q9HWZ3    ), 
AQPZ_PSEPK  (Q88F17    ), AQPZ_RHOPA  (P60925    ), AQPZ_SHEON  (Q8EHC1    ), 
AQPZ_SHIFL  (O68874    ), AQPZ_SYNY3  (P73809    ), AQPZ_VIBPA  (Q87MQ5    ), 
AQPZ_VIBVU  (Q8DB17    ), AQPZ_VIBVY  (Q7MIV9    ), AQP_AEDAE   (Q9NHW7    ), 
AQP_ANOGA   (Q7PWV1    ), AQP_DROME   (Q9V5Z7    ), AQP_ENCCU   (Q8SRK2    ), 
AQP_ENCHE   (Q1M1A0    ), AQP_ENCIN   (Q1M2P4    ), AQP_ENTBH   (B7XIC4    ), 
AQP_HAEIX   (Q25074    ), AQP_NOSCE   (C4VBN2    ), AQY1_YEAS7  (A6ZX66    ), 
AQY1_YEAS8  (C8ZJM1    ), AQY1_YEAST  (P0CD91    ), AQY1_YEASX  (P0CD92    ), 
AQY2_YEASX  (P0CD89    ), AQY3_YEAST  (P43549    ), BIB_DROME   (P23645    ), 
FPS1_YEAST  (P23900    ), GLA_LACLA   (Q9CE02    ), GLA_LACLC   (P22094    ), 
GLPF2_LACPL (F9USY3    ), GLPF3_LACPL (F9UTW9    ), GLPF5_LACPL (F9UUB3    ), 
GLPF_BACSU  (P18156    ), GLPF_BUCAI  (P57392    ), GLPF_BUCAP  (Q8K9M9    ), 
GLPF_ECO57  (P0AER2    ), GLPF_ECOL6  (P0AER1    ), GLPF_ECOLI  (P0AER0    ), 
GLPF_HAEIN  (P44826    ), GLPF_MYCGA  (P52280    ), GLPF_MYCGE  (P47279    ), 
GLPF_MYCPN  (P75071    ), GLPF_PSEAE  (Q51389    ), GLPF_SHIFL  (P31140    ), 
GLPF_STRCO  (P19255    ), GLPF_STRR6  (P0A3Q8    ), GLPF_THEMA  (Q9X1E3    ), 
HOG1_KLULA  (Q6CJA8    ), MIP_BOVIN   (P06624    ), MIP_CANLF   (A2IBY8    ), 
MIP_CAVPO   (Q6RZ07    ), MIP_CHICK   (P28238    ), MIP_HUMAN   (P30301    ), 
MIP_LITPI   (Q06019    ), MIP_MOUSE   (P51180    ), MIP_RABIT   (A4L9J0    ), 
MIP_RAT     (P09011    ), MIP_SHEEP   (Q6J8I9    ), NIP11_ARATH (Q8VZW1    ), 
NIP11_MAIZE (Q9ATN4    ), NIP11_ORYSJ (Q40746    ), NIP12_ARATH (Q8LFP7    ), 
NIP12_ORYSJ (Q0JPT5    ), NIP13_ORYSJ (Q0DK16    ), NIP14_ORYSJ (Q5Z9E2    ), 
NIP1_NICAL  (P49173    ), NIP21_ARATH (Q8W037    ), NIP21_MAIZE (Q19KC1    ), 
NIP21_ORYSJ (Q6Z2T3    ), NIP22_MAIZE (Q9ATN2    ), NIP22_ORYSJ (Q67WJ8    ), 
NIP23_MAIZE (Q9AT74    ), NIP31_ARATH (Q9C6T0    ), NIP31_MAIZE (Q9ATN1    ), 
NIP31_ORYSJ (Q0IWF3    ), NIP32_ORYSJ (Q7EYH7    ), NIP33_ORYSJ (Q84S07    ), 
NIP41_ARATH (Q9FIZ9    ), NIP41_ORYSJ (Q9ASI1    ), NIP42_ARATH (Q8W036    ), 
NIP51_ARATH (Q9SV84    ), NIP61_ARATH (Q9SAI4    ), NIP71_ARATH (Q8LAI1    ), 
NO26_SOYBN  (P08995    ), PDUF_CITFR  (B1VB61    ), PDUF_SALTY  (P37451    ), 
PIP11_ARATH (P61837    ), PIP11_MAIZE (Q41870    ), PIP11_MUSAC (S5ZH89    ), 
PIP11_ORYSJ (Q6EU94    ), PIP11_VICFA (P61838    ), PIP12_ARATH (Q06611    ), 
PIP12_MAIZE (Q9XF59    ), PIP12_MUSAC (P0DO53    ), PIP12_MUSAM (A0A804KTT0), 
PIP12_ORYSJ (Q7XSQ9    ), PIP13_ARATH (Q08733    ), PIP13_MAIZE (Q9AQU5    ), 
PIP13_ORYSJ (Q9SXF8    ), PIP14_ARATH (Q39196    ), PIP15_ARATH (Q8LAA6    ), 
PIP15_MAIZE (Q9AR14    ), PIP16_MAIZE (Q9ATN0    ), PIP1_ATRCA  (P42767    ), 
PIP1_SOLLC  (Q08451    ), PIP21_ARATH (P43286    ), PIP21_MAIZE (Q84RL7    ), 
PIP21_ORYSJ (Q8H5N9    ), PIP22_ARATH (P43287    ), PIP22_MAIZE (Q9ATM8    ), 
PIP22_ORYSJ (Q6K215    ), PIP23_ARATH (P30302    ), PIP23_MAIZE (Q9ATM7    ), 
PIP23_ORYSJ (Q7XUA6    ), PIP24_ARATH (Q9FF53    ), PIP24_MAIZE (Q9ATM6    ), 
PIP24_ORYSJ (Q8GRT8    ), PIP25_ARATH (Q9SV31    ), PIP25_MAIZE (Q9XF58    ), 
PIP25_ORYSJ (Q8GRI8    ), PIP26_ARATH (Q9ZV07    ), PIP26_MAIZE (Q9ATM5    ), 
PIP26_ORYSJ (Q7XLR1    ), PIP27_ARATH (P93004    ), PIP27_MAIZE (Q9ATM4    ), 
PIP27_MUSAC (A0A6M3QG69), PIP27_ORYSJ (Q651D5    ), PIP28_ARATH (Q9ZVX8    ), 
PIP28_ORYSJ (Q7Y1E6    ), PIP2_PEA    (P25794    ), TIP11_ARATH (P25818    ), 
TIP11_MAIZE (O64964    ), TIP11_ORYSJ (P50156    ), TIP12_ARATH (Q41963    ), 
TIP12_MAIZE (Q9ATM0    ), TIP12_MUSAC (P0DO54    ), TIP12_ORYSJ (Q94CS9    ), 
TIP13_ARATH (O82598    ), TIP1_MEDTR  (Q9FY14    ), TIP1_TOBAC  (P21653    ), 
TIP21_ARATH (Q41951    ), TIP21_MAIZE (Q9ATL9    ), TIP21_ORYSJ (Q7XA61    ), 
TIP22_ARATH (Q41975    ), TIP22_MAIZE (Q9ATL8    ), TIP22_ORYSJ (Q5Z6F0    ), 
TIP23_ARATH (Q9FGL2    ), TIP23_MAIZE (Q84RL6    ), TIP2_TOBAC  (P24422    ), 
TIP31_ARATH (P26587    ), TIP31_MAIZE (Q9ATL7    ), TIP31_ORYSJ (Q9FWV6    ), 
TIP32_ARATH (O22588    ), TIP32_MAIZE (Q9AT75    ), TIP32_ORYSJ (Q7XKI5    ), 
TIP41_ARATH (O82316    ), TIP41_MAIZE (Q9ATL6    ), TIP41_ORYSJ (Q75GA5    ), 
TIP42_MAIZE (Q9ATL5    ), TIP42_ORYSJ (Q9LWR0    ), TIP43_MAIZE (Q9ATL4    ), 
TIP43_ORYSJ (Q9LWR2    ), TIP44_MAIZE (Q9ATL3    ), TIP51_ARATH (Q9STX9    ), 
TIP51_MAIZE (Q9ATL2    ), TIP51_ORYSJ (Q7XU31    ), TIPA_PHAVU  (P23958    ), 
TIP_ANTMA   (P33560    ), Y9877_DICDI (Q54QI2    ), YI7H_SCHPO  (Q9P7T9    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 44 sequences 

AQ12A_HUMAN (Q8IXF9    ), AQ12B_HUMAN (A6NM10    ), AQP10_CAEEL (Q09369    ), 

AQP11_HUMAN (Q8NBQ7    ), AQP11_MOUSE (Q8BHH1    ), AQP11_RAT   (Q8CHM1    ), 
AQP12_MOUSE (Q8CHJ2    ), AQP1_BOTFB  (A0A384JL97), AQP1_GIBZE  (V6QVS3    ), 
AQP1_LACBI  (I1Z8E5    ), AQP1_LACBS  (B0DMR6    ), AQP1_RHIIR  (I3W9F6    ), 
AQP2_BOTFB  (A0A384J441), AQP3_GIBZE  (V6R6F0    ), AQP3_LACBI  (I1Z8E6    ), 
AQP3_LACBS  (B0DPL3    ), AQP4_BOTFB  (A0A384JPP3), AQP4_LACBS  (B0DAC6    ), 
AQP5_BOTFB  (A0A384J983), AQP5_GIBZE  (V6RVB4    ), AQP6_BOTFB  (A0A384JGJ4), 
AQP73_HUMAN (A6NL99    ), AQP7_BOTFB  (A0A384J409), AQP7_HUMAN  (O14520    ), 
AQP7_MACFA  (Q4R691    ), AQP7_MOUSE  (O54794    ), AQP7_RAT    (P56403    ), 
AQPS_RHIME  (Q92R43    ), AQP_CICVR   (Q23808    ), AQY2_YEAST  (P0CD90    ), 
GLPF4_LACPL (F9UMX3    ), GLPF6_LACPL (F9UUD2    ), GLPF_STRPN  (P0A3Q7    ), 
LARD_LACPL  (F9UST3    ), SIP11_ARATH (Q9M8W5    ), SIP11_MAIZE (Q9ATM3    ), 
SIP11_ORYSJ (Q5VR89    ), SIP12_ARATH (Q9FK43    ), SIP12_MAIZE (Q9ATM2    ), 
SIP21_ARATH (Q9M1K3    ), SIP21_MAIZE (Q9ATM1    ), TIP1_MEDSA  (P42067    ), 
Y1017_HAEIN (O86231    ), YLL53_YEAST (P0CD98    )
» more

UniProtKB/Swiss-Prot
False positive sequences		 21 sequences 

AMPP2_TRIVH (D4D6B8    ), DPP4_ASPFN  (B8N970    ), DPP4_ASPOR  (Q2UH35    ), 

DPPD_BACSU  (P26905    ), DTX_DROME   (Q23985    ), EAF1_YARLI  (Q6C7K8    ), 
GRS12_ARATH (Q8LBS4    ), IDD4_ARATH  (Q8GYC1    ), IDD6_ARATH  (Q8RWX7    ), 
LST2_MOUSE  (Q6ZPK7    ), MENE_HAEIN  (P44565    ), MODD_RHOCA  (Q08384    ), 
MYCP1_HUMAN (P12525    ), POLG_POWVL  (Q04538    ), RDF_BPPHC   (Q9T216    ), 
SC24B_HUMAN (O95487    ), SEC24_DICDI (Q54U61    ), SWAHB_HUMAN (A6NEL2    ), 
THI1_ORYSJ  (Q7XXS4    ), XB34_ORYSJ  (Q7XI08    ), YEA8_SCHPO  (O14073    )
» more

PDB
[Detailed view]		 49 PDB

1FQY; 1FX8; 1H6I; 1IH5; 1J4N; 1LDA; 1LDF; 1LDI; 1RC2; 1SOR; 1YMG; 2ABM; 2B6O; 2B6P; 2C32; 2D57; 2EVU; 2F2B; 2O9D; 2O9E; 2O9F; 2O9G; 2ZZ9; 3D9S; 3GD8; 3IYZ; 3J41; 3LLQ; 3M9I; 3NE2; 3NK5; 3NKA; 3NKC; 4CSK; 4NEF; 4OJ2; 5C5X; 5DYE; 5I32; 6F7H; 6POJ; 6QF5; 6QIM; 7CJS; 7NL4; 7STC; 7UZE; 8CT2; 8CTE
» more