PROSITE entry PS00222

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

Entry name [info]	IGFBP_N_1
Accession [info]	PS00222
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00194

Name and characterization of the entry

Description [info]	Insulin-like growth factor-binding protein (IGFBP) N-terminal domain signature.
Pattern [info]	[GP]-C-[GSET]-[CE]-[CA]-x(2)-C-[ALP]-x(6)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.

Total number of hits	60 in 60 different sequences
Number of true positive hits	60 in 60 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	18
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	76.92 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	60 sequences CCN1_CHICK (P19336), CCN1_HUMAN (O00622), CCN1_MOUSE (P18406), CCN1_PANTR (A5A6L1), CCN1_RAT(Q9ES72), CCN2_BOVIN (O18739), CCN2_HUMAN (P29279), CCN2_MOUSE (P29268), CCN2_PIG(O19113), CCN2_RAT(Q9R1E9), CCN3_CHICK (P28686), CCN3_COTJA (P42642), CCN3_HUMAN (P48745), CCN3_MOUSE (Q64299), CCN3_RAT(Q9QZQ5), CCN3_XENLA (P51609), CCN4_HUMAN (O95388), CCN4_MOUSE (O54775), CCN4_RAT(Q99PP0), CCN5_HUMAN (O76076), CCN5_MOUSE (Q9Z0G4), CCN5_RAT(Q9JHC6), CCN6_HUMAN (O95389), CCN6_MOUSE (D3Z5L9), IBP1_BOVIN (P24591), IBP1_HUMAN (P08833), IBP1_ICTTR (Q6Q484), IBP1_MOUSE (P47876), IBP1_RAT(P21743), IBP2A_DANRE (Q9PTH3), IBP2B_DANRE (B3F211), IBP2_BOVIN (P13384), IBP2_CHICK (P49705), IBP2_HUMAN (P18065), IBP2_MOUSE (P47877), IBP2_PIG(P24853), IBP2_RAT(P12843), IBP2_SHEEP (Q29400), IBP2_XENLA (Q5XHC5), IBP2_XENTR (A4IIA2), IBP3_BOVIN (P20959), IBP3_HUMAN (P17936), IBP3_MOUSE (P47878), IBP3_PIG(P16611), IBP3_RAT(P15473), IBP4_BOVIN (Q05716), IBP4_HUMAN (P22692), IBP4_MOUSE (P47879), IBP4_PIG(P24854), IBP4_RAT(P21744), IBP4_SHEEP (Q28893), IBP5_BOVIN (Q05717), IBP5_HUMAN (P24593), IBP5_MOUSE (Q07079), IBP5_PIG(Q28985), IBP5_RAT(P24594), IBP5_XENLA (Q90WV8), IBP6_MOUSE (P47880), PLSLP_LOTGI (B3A0Q9), PLS_HALLA (P82595) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	18 sequences HTR1B_DANRE (A9JRB3), HTRA1_BOVIN (F1N152), HTRA1_XENLA (A6YFB5), HTRA1_XENTR (A4IHA1), HTRA3_HUMAN (P83110), HTRA3_MOUSE (Q9D236), HTRA3_RAT (D3ZA76), HTRA4_BOVIN (E1BJW1), HTRA4_MOUSE (A2RT60), HTRA4_RAT (D3ZKF5), IBP6_BOVIN (Q05718), IBP6_HUMAN (P24592), IBP6_RAT(P35572), IGFBP_CUPSA (G4V4G1), SIBD1_CUPSA (G4V4F9), SIBD2_CUPSA (G4V4G0), VP302_LYCMC (P0CJ14), VP59_LYCMC (P0CJ12) » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence IBP2_ONCTS (P83628)
PDB [Detailed view]	6 PDB 1WQJ; 2DSP; 2DSQ; 2DSR; 7UFG; 7WRQ