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PROSITE entry PS00226


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General information about the entry

Entry name [info] IF_ROD_1
Accession [info] PS00226
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
08-NOV-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00198

Name and characterization of the entry

Description [info] Intermediate filament (IF) rod domain signature.
Pattern [info] 
[IV]-{K}-[TACI]-Y-[RKH]-{E}-[LM]-L-[DE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_05 which contains 570'420 sequence entries.


Total number of hits 312 in 312 different sequences
Number of true positive hits 291 in 291 different sequences
Number of 'unknown' hits 0
Number of false positive hits 21 in 21 different sequences
Number of false negative sequences 55
Number of 'partial' sequences 9
Precision (true positives / (true positives + false positives)) 93.27 %
Recall (true positives / (true positives + false negatives)) 84.10 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 291 sequences 

AINX_BOVIN  (Q08DH7), AINX_HUMAN  (Q16352), AINX_MOUSE  (P46660), 

AINX_RAT(P23565), AV71_ACAVI  (Q17107), DESM_BOVIN  (O62654), 
DESM_CANLF  (Q5XFN2), DESM_CHICK  (P02542), DESM_HUMAN  (P17661), 
DESM_MESAU  (P02541), DESM_MOUSE  (P31001), DESM_PIG(P02540), 
DESM_RAT(P48675), DESM_XENLA  (P23239), GFAP_BOVIN  (Q28115), 
GFAP_CARAU  (P48677), GFAP_DANRE  (Q58EE9), GFAP_HUMAN  (P14136), 
GFAP_MOUSE  (P03995), GFAP_PONAB  (Q5RA72), GFAP_RAT(P47819), 
IF3T_TETCF  (P23729), IFA1_CAEEL  (P90901), IFA4_CAEEL  (P90900), 
IFB1_CAEEL  (Q19289), IFEA_ASCSU  (P23730), IFEA_CORAP  (P22488), 
IFEA_HELPO  (P16274), IFEB_ASCSU  (P23731), IFEB_HELPO  (P16275), 
IFE_BRALA   (Q04948), ION3_CARAU  (P18520), K118A_POLSE (A1KQY9), 
K118A_XENLA (P08802), K118B_XENLA (Q7SY65), K1C0_XENLA  (P02537), 
K1C10_BOVIN (P06394), K1C10_CANLF (Q6EIZ0), K1C10_HUMAN (P13645), 
K1C10_MOUSE (P02535), K1C10_RAT   (Q6IFW6), K1C11_LAMFL (Q8AWA7), 
K1C11_PROAT (Q5K2P6), K1C12_HUMAN (Q99456), K1C12_MOUSE (Q64291), 
K1C12_RABIT (Q28706), K1C12_RAT   (Q6IFW5), K1C13_HUMAN (P13646), 
K1C13_MOUSE (P08730), K1C13_PROAT (Q5K2P4), K1C13_RAT   (Q6IFV4), 
K1C14_BOVIN (P05785), K1C14_CHICK (Q6PVZ1), K1C14_HUMAN (P02533), 
K1C14_MOUSE (Q61781), K1C14_RAT   (Q6IFV1), K1C15_HUMAN (P19012), 
K1C15_MOUSE (Q61414), K1C15_PROAT (Q5K2P2), K1C15_RAT   (Q6IFV3), 
K1C15_SHEEP (O77727), K1C16_HUMAN (P08779), K1C16_MOUSE (Q9Z2K1), 
K1C17_BOVIN (A1L595), K1C17_HUMAN (Q04695), K1C17_MOUSE (Q9QWL7), 
K1C17_PANTR (A5A6M0), K1C17_RAT   (Q6IFU8), K1C18_ACIBE (Q7SYF8), 
K1C18_CARAU (Q07427), K1C18_DANRE (Q7ZTS4), K1C18_HUMAN (P05783), 
K1C18_MOUSE (P05784), K1C18_ONCMY (O57607), K1C18_RAT   (Q5BJY9), 
K1C18_SCYST (O57611), K1C18_XENTR (Q6P864), K1C19_BOVIN (P08728), 
K1C19_CHICK (O93256), K1C19_HUMAN (P08727), K1C19_MOUSE (P19001), 
K1C19_PONAB (Q5R8S9), K1C19_POTTR (P51856), K1C19_RAT   (Q63279), 
K1C1_XENLA  (P08777), K1C20_BOVIN (A6QQQ9), K1C20_HUMAN (P35900), 
K1C20_MOUSE (Q9D312), K1C20_RAT   (P25030), K1C23_HUMAN (Q9C075), 
K1C23_MOUSE (Q99PS0), K1C24_HUMAN (Q2M2I5), K1C39_HUMAN (Q6A163), 
K1C39_MOUSE (Q6IFX4), K1C39_RAT   (Q6IFW3), K1C40_MOUSE (Q6IFX3), 
K1C40_RAT   (Q6IFW2), K1C42_MOUSE (Q6IFX2), K1C42_RAT   (Q6IFU7), 
K1C4_XENLA  (P05781), K1C5_XENLA  (P08778), K1C9_HUMAN  (P35527), 
K1C9_RAT(Q8CIS9), K1H1_HUMAN  (Q15323), K1H1_MOUSE  (Q61765), 
K1H1_PANTR  (A5A6M5), K1H2_HUMAN  (Q14532), K1H2_MOUSE  (Q62168), 
K1M1_SHEEP  (P02534), K1M2_SHEEP  (P25690), K22E_CANLF  (Q6EIZ1), 
K22E_HUMAN  (P35908), K22E_MOUSE  (Q3TTY5), K22E_RAT(Q6IG02), 
K22O_HUMAN  (Q01546), K22O_MOUSE  (Q3UV17), K2C1B_HUMAN (Q7Z794), 
K2C1B_MOUSE (Q6IFZ6), K2C1_CANLF  (Q6EIY9), K2C1_HUMAN  (P04264), 
K2C1_MOUSE  (P04104), K2C1_PANTR  (A5A6M6), K2C1_RAT(Q6IMF3), 
K2C1_XENLA  (P04266), K2C2_XENLA  (P04265), K2C3_BOVIN  (P04261), 
K2C3_HUMAN  (P12035), K2C3_RABIT  (Q29426), K2C4_BOVIN  (P04260), 
K2C4_HUMAN  (P19013), K2C4_MOUSE  (P07744), K2C4_RAT(Q6IG00), 
K2C5_BOVIN  (Q5XQN5), K2C5_HUMAN  (P13647), K2C5_MOUSE  (Q922U2), 
K2C5_PANTR  (A5A6M8), K2C5_RAT(Q6P6Q2), K2C6A_HUMAN (P02538), 
K2C6A_MOUSE (P50446), K2C6A_RAT   (Q4FZU2), K2C6B_HUMAN (P04259), 
K2C6B_MOUSE (Q9Z331), K2C6C_HUMAN (P48668), K2C71_BOVIN (Q148H5), 
K2C71_FELCA (E1AB55), K2C71_HUMAN (Q3SY84), K2C71_MOUSE (Q9R0H5), 
K2C72_BOVIN (Q148H8), K2C72_HUMAN (Q14CN4), K2C72_MOUSE (Q6IME9), 
K2C72_RAT   (Q6IG04), K2C73_BOVIN (A7YWK3), K2C73_HUMAN (Q86Y46), 
K2C73_MOUSE (Q6NXH9), K2C73_RAT   (Q6IG03), K2C74_HUMAN (Q7RTS7), 
K2C74_MOUSE (Q6IFZ9), K2C75_BOVIN (Q08D91), K2C75_HUMAN (O95678), 
K2C75_MOUSE (Q8BGZ7), K2C75_RAT   (Q6IG05), K2C78_BOVIN (A6QNX5), 
K2C78_HUMAN (Q8N1N4), K2C79_BOVIN (Q148H7), K2C79_HUMAN (Q5XKE5), 
K2C79_MOUSE (Q8VED5), K2C7_BOVIN  (Q29S21), K2C7_HUMAN  (P08729), 
K2C7_MOUSE  (Q9DCV7), K2C7_PANTR  (A5A6N0), K2C7_POTTR  (Q8HZR5), 
K2C7_RAT(Q6IG12), K2C7_XENLA  (P16878), K2C8_BOVIN  (P05786), 
K2C8_DANRE  (Q6NWF6), K2C8_HUMAN  (P05787), K2C8_MOUSE  (P11679), 
K2C8_PROAT  (Q5K2N3), K2C8_RAT(Q10758), K2C8_XENLA  (P08776), 
K2CA_BOVIN  (P04263), K2CB_BOVIN  (P04262), K2CO_CHICK  (O93532), 
K2M2_SHEEP  (P15241), K2M3_SHEEP  (P25691), KRT34_HUMAN (O76011), 
KRT34_MOUSE (Q9D646), KRT35_BOVIN (Q0P5J7), KRT35_HUMAN (Q92764), 
KRT35_MOUSE (Q497I4), KRT35_SHEEP (B0LKP1), KRT36_HUMAN (O76013), 
KRT36_MOUSE (B1AQ75), KRT37_HUMAN (O76014), KRT38_HUMAN (O76015), 
KRT81_BOVIN (Q148H4), KRT81_HUMAN (Q14533), KRT81_MOUSE (Q9ERE2), 
KRT82_HUMAN (Q9NSB4), KRT82_MOUSE (Q99M74), KRT83_BOVIN (A4FUZ0), 
KRT83_HUMAN (P78385), KRT84_HUMAN (Q9NSB2), KRT84_MOUSE (Q99M73), 
KRT85_HUMAN (P78386), KRT85_MOUSE (Q9Z2T6), KRT86_HUMAN (O43790), 
KRT86_MOUSE (P97861), KRT87_MOUSE (Q6IMF0), KT222_BOVIN (Q2KI75), 
KT222_HUMAN (Q8N1A0), KT222_MOUSE (Q8CCX5), KT33A_HUMAN (O76009), 
KT33A_MOUSE (Q8K0Y2), KT33A_PANTR (A5A6P3), KT33B_HUMAN (Q14525), 
KT33B_MOUSE (Q61897), LAML1_XENLA (P09010), LAML2_XENLA (P21910), 
LAML3_XENLA (P10999), LMNA_CHICK  (P13648), LMNA_HUMAN  (P02545), 
LMNA_MOUSE  (P48678), LMNA_PIG(Q3ZD69), LMNA_RAT(P48679), 
LMNA_XENLA  (P11048), LMNB1_CHICK (P14731), LMNB1_HUMAN (P20700), 
LMNB1_MOUSE (P14733), LMNB1_RAT   (P70615), LMNB2_CHICK (P14732), 
LMNB2_HUMAN (Q03252), LMNB2_MOUSE (P21619), NEST_DANRE  (P86839), 
NEST_HUMAN  (P48681), NEST_MESAU  (Q9Z1Q1), NEST_MOUSE  (Q6P5H2), 
NEST_RAT(P21263), NF60_DORPE  (Q01240), NF70_DORPE  (Q01241), 
NFH_HUMAN   (P12036), NFH_MOUSE   (P19246), NFH_RAT (P16884), 
NFL_BOVIN   (P02548), NFL_COTJA   (Q02916), NFL_HUMAN   (P07196), 
NFL_MOUSE   (P08551), NFL_PIG (P02547), NFL_PONAB   (Q5R408), 
NFL_RAT (P19527), NFL_XENLA   (P35616), NFL_XENTR   (B4F721), 
NFM_BOVIN   (O77788), NFM_CHICK   (P16053), NFM_HUMAN   (P07197), 
NFM_MOUSE   (P08553), NFM_PIG (P08552), NFM_RABIT   (P54938), 
NFM_RAT (P12839), OV71_ONCVO  (P31732), PERI_BOVIN  (A6QQJ3), 
PERI_HUMAN  (P41219), PERI_MOUSE  (P15331), PERI_RAT(P21807), 
PERI_XENLA  (P48676), PLST_CARAU  (P31393), RGP51_LYMST (Q6QUW1), 
SYNEM_HUMAN (O15061), SYNEM_MOUSE (Q70IV5), TANA_XENLA  (Q01550), 
TBFA_EPTST  (Q90501), TBFG_EPTST  (Q90502), VIM1_CARAU  (P48671), 
VIM1_XENLA  (P24789), VIM2_CARAU  (P48672), VIM4_XENLA  (P24790), 
VIMB_CARAU  (P48673), VIME_BOVIN  (P48616), VIME_CHICK  (P09654), 
VIME_CHLAE  (P84198), VIME_CRIGR  (P48670), VIME_CYPCA  (Q92155), 
VIME_HUMAN  (P08670), VIME_MACFA  (Q4R4X4), VIME_MESAU  (P02544), 
VIME_MOUSE  (P20152), VIME_ONCMY  (P48674), VIME_PANTR  (Q5R1W8), 
VIME_PIG(P02543), VIME_RAT(P31000), XNIF_XENLA  (P35617)
» more

UniProtKB/Swiss-Prot
False negative sequences		 55 sequences 

BFSP1_BOVIN (Q06002), BFSP1_CHICK (Q06637), BFSP1_HUMAN (Q12934), 

BFSP1_MOUSE (A2AMT1), BFSP1_RAT   (Q02435), BFSP2_BOVIN (Q28177), 
BFSP2_HUMAN (Q13515), BFSP2_MOUSE (Q6NVD9), IFA2_CAEEL  (O02365), 
IFA3_CAEEL  (Q21065), IFB2_CAEEL  (Q19286), IFC1_CAEEL  (O45168), 
IFC2_CAEBR  (Q5WN60), IFC2_CAEEL  (Q21067), IFD1_CAEEL  (Q86DC6), 
IFD2_CAEEL  (Q19782), IFP1_CAEEL  (Q09501), K1C13_ONCMY (Q8JFQ6), 
K1C1_CARAU  (Q90303), K1C24_MOUSE (A1L317), K1C24_RAT   (Q6IFX1), 
K1C25_BOVIN (Q0P5J4), K1C25_CAPHI (Q6R650), K1C25_HUMAN (Q7Z3Z0), 
K1C25_MOUSE (Q8VCW2), K1C25_PANTR (A5A6N2), K1C25_RAT   (Q6IFX0), 
K1C25_SHEEP (Q9BGM5), K1C26_BOVIN (A6H712), K1C26_HUMAN (Q7Z3Y9), 
K1C26_MOUSE (Q3TRJ4), K1C27_BOVIN (Q0P5J6), K1C27_CAPHI (Q6R649), 
K1C27_HUMAN (Q7Z3Y8), K1C27_MOUSE (Q9Z320), K1C27_RAT   (Q6IFW8), 
K1C28_BOVIN (Q148H6), K1C28_HUMAN (Q7Z3Y7), K1C28_MOUSE (A6BLY7), 
K1C40_BOVIN (A7YWM2), K1C40_HUMAN (Q6A162), K1C9_CANLF  (O18740), 
K1C9_MOUSE  (Q6RHW0), K2C1B_RAT   (Q6IG01), K2C74_BOVIN (A3KN27), 
K2C80_BOVIN (A0JND2), K2C80_HUMAN (Q6KB66), K2C80_MOUSE (Q0VBK2), 
K2C80_RAT   (Q6IMF1), KR87P_HUMAN (A6NCN2), LAM0_DROME  (P08928), 
LAMC_DROME  (Q03427), LMN1_CAEEL  (Q21443), SYNCI_HUMAN (Q9H7C4), 
SYNCI_MOUSE (Q9EPM5)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 9 sequences 

K1C19_MESAU (P86246), K1C20_PIG   (Q29218), K1C3_XENLA  (P05782), 

K2C8_MESAU  (P86247), K2C8_POTTR  (Q28810), K2M1_SHEEP  (P02539), 
KRT_CEREL   (P86498), NFH_PIG (P12037), VIME_SHEEP  (Q9MZA9)
» more

UniProtKB/Swiss-Prot
False positive sequences		 21 sequences 

ADDB_DESRM  (A4J4E2), AIM6_CANGA  (Q6FWH9), ATPG_DESVH  (Q72E03), 

BAH_STRHY   (Q01109), CEMA_TUPAK  (Q3ZJ15), FAB1D_ARATH (Q9XID0), 
GLYL3_HUMAN (Q5SZD4), LIX1_CHICK  (Q8UVV7), LIX1_HUMAN  (Q8N485), 
LIX1_MOUSE  (Q6P566), LPH_RABIT   (P09849), LPH_SHEEP   (W5PLZ6), 
MEND_NOCSJ  (A1SE17), NCED2_ORYSJ (Q5MBR6), OGRL1_XENTR (A2VCV0), 
PPR36_ARATH (Q0WKV3), RFBF_BACSU  (O06486), RS10_NOVAD  (Q2G8Y1), 
RS10_SACD2  (Q21M58), TTC27_CAEEL (P41842), TYSY_SYMTH  (Q67JQ1)
» more

PDB
[Detailed view]		 13 PDB

1GK4; 1GK6; 1X8Y; 2XV5; 3TNU; 3TYY; 3V4Q; 3V4W; 3V5B; 4ZRY; 6JFV; 6UUI; 6YJD
» more