PROSITE logo

PROSITE entry PS00236


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] NEUROTR_ION_CHANNEL
Accession [info] PS00236
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00209

Name and characterization of the entry

Description [info] Neurotransmitter-gated ion-channels signature.
Pattern [info] 
C-x-[LIVMFQ]-x-[LIVMF]-x(2)-[FY]-P-x-D-x(3)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 252 in 252 different sequences
Number of true positive hits 252 in 252 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.44 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 252 sequences 

5HT3A_CAVPO (O70212), 5HT3A_HUMAN (P46098), 5HT3A_MOUSE (P23979), 

5HT3A_RAT   (P35563), 5HT3C_HUMAN (Q8WXA8), 5HT3E_HUMAN (A5X5Y0), 
ACC1_CAEEL  (Q21005), ACC2_CAEEL  (Q18812), ACC3_CAEEL  (G5EDN0), 
ACH10_CHICK (Q9I8C7), ACH10_HUMAN (Q9GZZ6), ACH10_RAT   (Q9JLB5), 
ACH15_CAEEL (O16926), ACH1_CAEBR  (A8WQK3), ACH1_CAEEL  (P48180), 
ACH1_DROME  (P09478), ACH1_MANSE  (P91766), ACH1_SCHGR  (P23414), 
ACH23_CAEEL (G5EG88), ACH2_CAEEL  (P48181), ACH2_DROME  (P17644), 
ACH3_CAEEL  (P54244), ACH3_DROME  (P04755), ACH4_CAEEL  (O76554), 
ACH4_DROME  (P25162), ACH5_CAEEL  (Q23022), ACH6_CAEEL  (Q9N587), 
ACH7_CAEEL  (Q27218), ACH8_CAEBR  (Q60S81), ACH8_CAEEL  (Q9U298), 
ACH91_ONCMY (Q8JFN7), ACH92_ONCMY (Q68RJ7), ACHA2_CHICK (P09480), 
ACHA2_HUMAN (Q15822), ACHA2_MOUSE (Q91X60), ACHA2_PANTR (Q5IS52), 
ACHA2_RAT   (P12389), ACHA3_BOVIN (Q07263), ACHA3_CARAU (P18845), 
ACHA3_CHICK (P09481), ACHA3_HUMAN (P32297), ACHA3_MOUSE (Q8R4G9), 
ACHA3_RAT   (P04757), ACHA4_CHICK (P09482), ACHA4_HUMAN (P43681), 
ACHA4_MOUSE (O70174), ACHA4_MUSPF (Q19AE6), ACHA4_PANTR (Q5IS77), 
ACHA4_RAT   (P09483), ACHA5_BOVIN (Q8SPU7), ACHA5_CHICK (P26152), 
ACHA5_HUMAN (P30532), ACHA5_MOUSE (Q2MKA5), ACHA5_PANTR (Q5IS51), 
ACHA5_RAT   (P20420), ACHA6_CHICK (P49581), ACHA6_HUMAN (Q15825), 
ACHA6_MOUSE (Q9R0W9), ACHA6_PANTR (Q5IS76), ACHA6_RAT   (P43143), 
ACHA7_BOVIN (P54131), ACHA7_CHICK (P22770), ACHA7_HUMAN (P36544), 
ACHA7_MACMU (Q866A2), ACHA7_MOUSE (P49582), ACHA7_RAT   (Q05941), 
ACHA9_CHICK (Q9PTS8), ACHA9_HUMAN (Q9UGM1), ACHA9_RAT   (P43144), 
ACHAA_XENLA (P22456), ACHAB_XENLA (P05377), ACHA_BOVIN  (P02709), 
ACHA_CHICK  (P09479), ACHA_CRORS  (P54248), ACHA_DANRE  (Q98880), 
ACHA_ERICO  (P54249), ACHA_FELCA  (P54250), ACHA_HERIC  (P54251), 
ACHA_HUMAN  (P02708), ACHA_MOUSE  (P04756), ACHA_NAJNA  (P14143), 
ACHA_NATTE  (P14144), ACHA_RAT(P25108), ACHA_TETCF  (P02710), 
ACHA_TORMA  (P02711), ACHB2_CARAU (P19370), ACHB2_CHICK (P09484), 
ACHB2_HUMAN (P17787), ACHB2_MOUSE (Q9ERK7), ACHB2_RAT   (P12390), 
ACHB3_CHICK (P43679), ACHB3_HUMAN (Q05901), ACHB3_MOUSE (Q8BMN3), 
ACHB3_PANTR (Q5IS75), ACHB3_RAT   (P12391), ACHB4_BOVIN (Q8SPU6), 
ACHB4_CHICK (P26153), ACHB4_HUMAN (P30926), ACHB4_MOUSE (Q8R493), 
ACHB4_RAT   (P12392), ACHB_BOVIN  (P04758), ACHB_HUMAN  (P11230), 
ACHB_MOUSE  (P09690), ACHB_RAT(P25109), ACHB_TETCF  (P02712), 
ACHB_XENLA  (P49579), ACHD_BOVIN  (P04759), ACHD_CHICK  (P02717), 
ACHD_HUMAN  (Q07001), ACHD_MOUSE  (P02716), ACHD_RAT(P25110), 
ACHD_TETCF  (P02718), ACHD_XENLA  (P09628), ACHE_BOVIN  (P02715), 
ACHE_HUMAN  (Q04844), ACHE_MOUSE  (P20782), ACHE_RAT(P09660), 
ACHE_XENLA  (P49580), ACHG_BOVIN  (P13536), ACHG_CHICK  (P02713), 
ACHG_HUMAN  (P07510), ACHG_MOUSE  (P04760), ACHG_RAT(P18916), 
ACHG_TETCF  (P02714), ACHG_XENLA  (P05376), ACHN2_CARAU (P13908), 
ACHN3_CARAU (P18257), ACHX_ONCVO  (P54247), ACR2_CAEEL  (P48182), 
ACR3_CAEEL  (Q93149), ACR5_CAEEL  (P54246), ACR7_CAEEL  (P45963), 
ARKA_DICDI  (Q54HC6), CRFM7_HUMAN (Q494W8), CUP4_CAEBR  (A8XF54), 
CUP4_CAEEL  (P34271), GBR1_CAEEL  (G5ECJ0), GBRA1_BOVIN (P08219), 
GBRA1_CHICK (P19150), GBRA1_HUMAN (P14867), GBRA1_MACFA (Q4R534), 
GBRA1_MOUSE (P62812), GBRA1_PONAB (Q5R6B2), GBRA1_RAT   (P62813), 
GBRA2_BOVIN (P10063), GBRA2_HUMAN (P47869), GBRA2_MOUSE (P26048), 
GBRA2_PONAB (Q5RCC5), GBRA2_RAT   (P23576), GBRA3_BOVIN (P10064), 
GBRA3_HUMAN (P34903), GBRA3_MOUSE (P26049), GBRA3_RAT   (P20236), 
GBRA4_BOVIN (P20237), GBRA4_HUMAN (P48169), GBRA4_MOUSE (Q9D6F4), 
GBRA4_RAT   (P28471), GBRA5_BOVIN (Q08E50), GBRA5_HUMAN (P31644), 
GBRA5_MOUSE (Q8BHJ7), GBRA5_RAT   (P19969), GBRA6_CHICK (Q90845), 
GBRA6_HUMAN (Q16445), GBRA6_MOUSE (P16305), GBRA6_RAT   (P30191), 
GBRAL_DROME (Q24352), GBRB1_BOVIN (P08220), GBRB1_HUMAN (P18505), 
GBRB1_MOUSE (P50571), GBRB1_RAT   (P15431), GBRB2_BOVIN (P0C2W5), 
GBRB2_HUMAN (P47870), GBRB2_MACMU (D1LYT2), GBRB2_MOUSE (P63137), 
GBRB2_RAT   (P63138), GBRB3_CHICK (P19019), GBRB3_DROME (Q08832), 
GBRB3_HUMAN (P28472), GBRB3_MOUSE (P63080), GBRB3_RAT   (P63079), 
GBRB4_CHICK (P24045), GBRB_CAEEL  (O18276), GBRB_DROME  (P25123), 
GBRB_DROSI  (Q9BLY8), GBRB_LYMST  (P26714), GBRB_MUSDO  (Q75NA5), 
GBRD_HUMAN  (O14764), GBRD_MOUSE  (P22933), GBRD_RAT(P18506), 
GBRE_HUMAN  (P78334), GBRE_RAT(Q9ES14), GBRG1_HUMAN (Q8N1C3), 
GBRG1_MOUSE (Q9R0Y8), GBRG1_RAT   (P23574), GBRG2_BOVIN (P22300), 
GBRG2_CHICK (P21548), GBRG2_HUMAN (P18507), GBRG2_MOUSE (P22723), 
GBRG2_PONAB (Q5REA1), GBRG2_RAT   (P18508), GBRG3_HUMAN (Q99928), 
GBRG3_MOUSE (P27681), GBRG3_RAT   (P28473), GBRG4_CHICK (P34904), 
GBRP_BOVIN  (Q5EA06), GBRP_HUMAN  (O00591), GBRP_MOUSE  (Q8QZW7), 
GBRP_RAT(O09028), GBRR1_HUMAN (P24046), GBRR1_MOUSE (P56475), 
GBRR1_RAT   (P50572), GBRR2_BOVIN (Q0II76), GBRR2_HUMAN (P28476), 
GBRR2_MOUSE (P56476), GBRR2_RAT   (P47742), GBRR3_HUMAN (A8MPY1), 
GBRR3_RAT   (P50573), GBRT_HUMAN  (Q9UN88), GBRT_MOUSE  (Q9JLF1), 
GLRA1_BOVIN (P57695), GLRA1_DANRE (O93430), GLRA1_HUMAN (P23415), 
GLRA1_MOUSE (Q64018), GLRA1_RAT   (P07727), GLRA2_DANRE (F1R8P4), 
GLRA2_HUMAN (P23416), GLRA2_MOUSE (Q7TNC8), GLRA2_RAT   (P22771), 
GLRA3_HUMAN (O75311), GLRA3_MOUSE (Q91XP5), GLRA3_RAT   (P24524), 
GLRA4_MOUSE (Q61603), GLRB4_CAEEL (Q09453), GLRB_BOVIN  (Q9GJS9), 
GLRB_HUMAN  (P48167), GLRB_MOUSE  (P48168), GLRB_RAT(P20781), 
GLUCB_CAEEL (Q17328), GLUCB_HAECO (P91730), GLUCL_CAEEL (G5EBR3), 
GLUCL_DROME (Q94900), LGC46_CAEEL (Q95Y52), LGC4_CAEBR  (A8XNX8), 
LGC4_CAEEL  (P54245), LGC50_CAEEL (P41849), MOD1_CAEEL  (Q9GQ00), 
PBO5_CAEEL  (G5ECT0), PBO6_CAEEL  (Q19351), PHCL2_ANOGA (A0A1S4H2E2), 
PHCL2_DROME (Q9V9Y4), ZACN_CANLF  (Q866Y9), ZACN_HUMAN  (Q401N2)
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

5HT3B_HUMAN (O95264), 5HT3B_MOUSE (Q9JHJ5), 5HT3B_RAT   (Q9JJ16), 

5HT3D_HUMAN (Q70Z44)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 5 sequences 

ACHA_ELEEL  (P09688), ACHB_CHICK  (P16005), ACHB_ELEEL  (P09689), 

ACHD_ELEEL  (P09691), ACHG_ELEEL  (P09692)
» more

PDB
[Detailed view]		 215 PDB

2BG9; 2QC1; 3JAD; 3JAE; 3JAF; 3RHW; 3RI5; 3RIA; 3RIF; 4AQ5; 4AQ9; 4BOG; 4BOI; 4BON; 4BOO; 4BOR; 4BOT; 4COF; 4D01; 4PIR; 4TNV; 4TNW; 4UXU; 4UY2; 5BKF; 5BKG; 5CFB; 5FJV; 5HBT; 5HBV; 5KXI; 5O8F; 5OJM; 5TIN; 5TIO; 5VDH; 5VDI; 6A96; 6BE1; 6CNJ; 6CNK; 6D6T; 6D6U; 6DG7; 6DG8; 6DW0; 6DW1; 6HIN; 6HIO; 6HIQ; 6HUG; 6HUJ; 6HUK; 6HUO; 6HUP; 6HY7; 6I53; 6NP0; 6PLO; 6PLP; 6PLQ; 6PLR; 6PLS; 6PLT; 6PLU; 6PLV; 6PLW; 6PLX; 6PLY; 6PLZ; 6PM0; 6PM1; 6PM2; 6PM3; 6PM4; 6PM5; 6PM6; 6PV7; 6PV8; 6PXD; 6QFA; 6UBS; 6UBT; 6UD3; 6UR8; 6USF; 6UWZ; 6VM0; 6VM2; 6VM3; 6W1J; 6W1M; 6W1Y; 6X3S; 6X3T; 6X3U; 6X3V; 6X3W; 6X3X; 6X3Z; 6X40; 6Y1Z; 7EKI; 7EKP; 7EKT; 7KOO; 7KOQ; 7KOX; 7KUY; 7L31; 7M6M; 7M6N; 7M6O; 7M6P; 7M6Q; 7M6R; 7M6S; 7PBD; 7PBZ; 7PC0; 7QKO; 7QL5; 7QL6; 7QN5; 7QN6; 7QN7; 7QN8; 7QN9; 7QNA; 7QNB; 7QNC; 7QND; 7QNE; 7SMM; 7SMQ; 7SMR; 7SMS; 7SMT; 7T0W; 7T0Z; 7TU9; 7TVI; 7U2M; 7U2N; 7U2O; 7Z14; 8A5U; 8AXD; 8BEJ; 8BGI; 8BHA; 8BHB; 8BHG; 8BHI; 8BHK; 8BHM; 8BHO; 8BHQ; 8BHR; 8BHS; 8C9X; 8CAU; 8CE4; 8CI1; 8CI2; 8DD2; 8DD3; 8DN2; 8DN3; 8DN4; 8DN5; 8ESK; 8F2S; 8F6Y; 8F6Z; 8FE1; 8FOI; 8FRW; 8FRX; 8FRZ; 8FSB; 8FSP; 8FSZ; 8G4N; 8G4O; 8G4X; 8G5F; 8G5G; 8G5H; 8OP9; 8OQ6; 8OQ7; 8OQ8; 8OQA; 8PVB; 8SGO; 8SI9; 8SID; 8SSZ; 8ST0; 8ST1; 8ST2; 8ST3; 8ST4; 8UT1; 8UTB; 8UZJ; 8V80; 8V82; 8V86; 8V88; 8V89; 8V8A; 8V8C; 8V8D
» more