PROSITE logo

PROSITE entry PS00239


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS00239

Direct ScanProsite submission
General information about the entry

Entry name [info] RECEPTOR_TYR_KIN_II
Accession [info] PS00239
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00212

Name and characterization of the entry

Description [info] Receptor tyrosine kinase class II signature.
Pattern [info] 
[DN]-[LIV]-Y-x(3)-Y-Y-R.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 57 in 57 different sequences
Number of true positive hits 54 in 54 different sequences
Number of 'unknown' hits 1
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 96.43 %
Recall (true positives / (true positives + false negatives)) 96.43 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] phosphorylation at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 54 sequences 

7LESS_DROME (P13368), 7LESS_DROVI (P20806), ALK_CANLF   (P0DV84), 

ALK_DANRE   (F8W3R9), ALK_HUMAN   (Q9UM73), ALK_MOUSE   (P97793), 
DDR1_HUMAN  (Q08345), DDR1_MOUSE  (Q03146), DDR1_PANTR  (Q7YR43), 
DDR1_RAT(Q63474), DDR2_HUMAN  (Q16832), DDR2_MOUSE  (Q62371), 
HTK7_HYDVU  (Q25197), IGF1R_BOVIN (Q05688), IGF1R_HUMAN (P08069), 
IGF1R_MOUSE (Q60751), IGF1R_RAT   (P24062), IGF1R_XENLA (O73798), 
ILPR_BRALA  (O02466), INSRR_CAVPO (P14617), INSRR_HUMAN (P14616), 
INSRR_MOUSE (Q9WTL4), INSRR_RAT   (Q64716), INSR_AEDAE  (Q93105), 
INSR_HUMAN  (P06213), INSR_MOUSE  (P15208), INSR_RAT(P15127), 
INSR_XENLA  (Q9PVZ4), LTK_DANRE   (F1QVU0), LTK_HUMAN   (P29376), 
LTK_MOUSE   (P08923), MIPR_LYMST  (Q25410), NTRK1_CHICK (Q91009), 
NTRK1_HUMAN (P04629), NTRK1_MOUSE (Q3UFB7), NTRK1_RAT   (P35739), 
NTRK2_CHICK (Q91987), NTRK2_HUMAN (Q16620), NTRK2_MOUSE (P15209), 
NTRK2_RAT   (Q63604), NTRK3_CHICK (Q91044), NTRK3_HUMAN (Q16288), 
NTRK3_MACFA (Q5IFJ9), NTRK3_MOUSE (Q6VNS1), NTRK3_PANTR (Q5IS37), 
NTRK3_PIG   (P24786), NTRK3_RAT   (Q03351), NTRK3_SAIBB (Q5IS82), 
ROR1_DROME  (Q24488), ROS1_CHICK  (P08941), ROS1_HUMAN  (P08922), 
ROS_AVISU   (P00529), RTK2_GEOCY  (P42159), TRK1_LYMST  (O76997)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

PTK7_HUMAN  (Q13308), PTK7_MOUSE  (Q8BKG3)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			2 sequences
			


			
IGF1R_PIG   (Q29000), INSR_MACMU  (Q28516)


				
	

	

		UniProtKB/Swiss-Prot
'Unknown' sequences		
		
			1 sequence
			


			
INSR_DROME  (P09208)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
KSL1_SALMI  (C8XPS0), OST1A_ORYSJ (Q0DJC5)


				
	

	

		PDB
[Detailed view]		
		
			250 PDB
			


			pdb_00001gag; pdb_00001i44; pdb_00001ir3; pdb_00001irk; pdb_00001jqh; pdb_00001k3a; pdb_00001m7n; pdb_00001p14; pdb_00001p4o; pdb_00001rqq; pdb_00002auh; pdb_00002b4s; 
			
				pdb_00002oj9; pdb_00002xb7; pdb_00002xba; pdb_00002xp2; pdb_00002yfx; pdb_00002yhv; pdb_00002yjr; pdb_00002yjs; pdb_00002z8c; pdb_00002zm3; pdb_00003aox; pdb_00003bu3; 
				pdb_00003bu5; pdb_00003bu6; pdb_00003d94; pdb_00003ekk; pdb_00003ekn; pdb_00003eta; pdb_00003f5p; pdb_00003i81; pdb_00003l9p; pdb_00003lcs; pdb_00003lct; pdb_00003lvp; 
				pdb_00003lw0; pdb_00003nw5; pdb_00003nw6; pdb_00003nw7; pdb_00003o23; pdb_00003qqu; pdb_00003v5q; pdb_00003zbf; pdb_00003zos; pdb_00004anl; pdb_00004anq; pdb_00004ans; 
				pdb_00004aoj; pdb_00004asz; pdb_00004at3; pdb_00004at4; pdb_00004at5; pdb_00004bkj; pdb_00004ccb; pdb_00004ccu; pdb_00004cd0; pdb_00004ckr; pdb_00004cli; pdb_00004clj; 
				pdb_00004cmo; pdb_00004cmt; pdb_00004cmu; pdb_00004cnh; pdb_00004ctb; pdb_00004ctc; pdb_00004d2r; pdb_00004dce; pdb_00004f0i; pdb_00004fnw; pdb_00004fnx; pdb_00004fny; 
				pdb_00004fnz; pdb_00004fob; pdb_00004foc; pdb_00004fod; pdb_00004gt5; pdb_00004ibm; pdb_00004joa; pdb_00004mkc; pdb_00004pmm; pdb_00004pmp; pdb_00004pms; pdb_00004pmt; 
				pdb_00004tt7; pdb_00004uxl; pdb_00004xlv; pdb_00004ymj; pdb_00004yne; pdb_00004yps; pdb_00004z55; pdb_00005a9u; pdb_00005aa8; pdb_00005aa9; pdb_00005aaa; pdb_00005aab; 
				pdb_00005aac; pdb_00005bvk; pdb_00005bvn; pdb_00005bvo; pdb_00005bvw; pdb_00005e1s; pdb_00005fdp; pdb_00005fdx; pdb_00005fto; pdb_00005ftq; pdb_00005fxq; pdb_00005fxr; 
				pdb_00005h3q; pdb_00005hhw; pdb_00005hzn; pdb_00005i8a; pdb_00005imx; pdb_00005iug; pdb_00005iuh; pdb_00005iui; pdb_00005jfs; pdb_00005jfv; pdb_00005jfw; pdb_00005jfx; 
				pdb_00005kmi; pdb_00005kmj; pdb_00005kmk; pdb_00005kml; pdb_00005kmm; pdb_00005kmn; pdb_00005kmo; pdb_00005kvt; pdb_00005kz0; pdb_00005sau; pdb_00005sav; pdb_00005saw; 
				pdb_00005sax; pdb_00005say; pdb_00005saz; pdb_00005sb0; pdb_00005sb1; pdb_00005sb2; pdb_00005wr7; pdb_00006brj; pdb_00006bsd; pdb_00006cdt; pdb_00006d1y; pdb_00006d1z; 
				pdb_00006d20; pdb_00006d22; pdb_00006dkb; pdb_00006dkg; pdb_00006dki; pdb_00006dkw; pdb_00006e0r; pdb_00006ebw; pdb_00006edl; pdb_00006fer; pdb_00006few; pdb_00006fex; 
				pdb_00006fil; pdb_00006fin; pdb_00006fio; pdb_00006fiq; pdb_00006gwr; pdb_00006hp9; pdb_00006iqn; pdb_00006j5l; pdb_00006jk8; pdb_00006kzc; pdb_00006kzd; pdb_00006mx8; 
				pdb_00006npt; pdb_00006nsp; pdb_00006nss; pdb_00006pl1; pdb_00006pl2; pdb_00006pl3; pdb_00006pl4; pdb_00006pma; pdb_00006pmb; pdb_00006pmc; pdb_00006pme; pdb_00006pxv; 
				pdb_00006pxw; pdb_00006pyh; pdb_00006y23; pdb_00007bcm; pdb_00007be6; pdb_00007btt; pdb_00007bw7; pdb_00007bw8; pdb_00007bwa; pdb_00007feh; pdb_00007jy4; pdb_00007jyr; 
				pdb_00007jys; pdb_00007jyt; pdb_00007pg0; pdb_00007pg2; pdb_00007pg3; pdb_00007pg4; pdb_00007r7k; pdb_00007r7r; pdb_00007sl1; pdb_00007sl2; pdb_00007sl3; pdb_00007sl4; 
				pdb_00007sl6; pdb_00007sl7; pdb_00007sth; pdb_00007sti; pdb_00007stj; pdb_00007stk; pdb_00007tyj; pdb_00007tyk; pdb_00007tym; pdb_00007vkm; pdb_00007vkn; pdb_00007vko; 
				pdb_00007xaf; pdb_00007xbi; pdb_00007z5w; pdb_00007z5x; pdb_00008arj; pdb_00008dtl; pdb_00008dtm; pdb_00008dwn; pdb_00008eyr; pdb_00008eyx; pdb_00008eyy; pdb_00008ez0; 
				pdb_00008j5w; pdb_00008j5x; pdb_00008j61; pdb_00008j63; pdb_00008pyi; pdb_00008pyj; pdb_00008pyk; pdb_00008pyl; pdb_00008pym; pdb_00008pyn; pdb_00008u4b; pdb_00008u4c; 
				pdb_00008u4e; pdb_00008vjb; pdb_00008vjc; pdb_00008x06; pdb_00008x2m; pdb_00008xjs; pdb_00008xk1; pdb_00008xkm; pdb_00008xkr; pdb_00009gbe
			
			

			» more