PROSITE logo

PROSITE entry PS00239


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] RECEPTOR_TYR_KIN_II
Accession [info] PS00239
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00212

Name and characterization of the entry

Description [info] Receptor tyrosine kinase class II signature.
Pattern [info] 
[DN]-[LIV]-Y-x(3)-Y-Y-R.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 57 in 57 different sequences
Number of true positive hits 55 in 55 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 2
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 96.49 %
Recall (true positives / (true positives + false negatives)) 96.49 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] phosphorylation at position 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 55 sequences 

7LESS_DROME (P13368), 7LESS_DROVI (P20806), ALK_CANLF   (P0DV84), 

ALK_DANRE   (F8W3R9), ALK_HUMAN   (Q9UM73), ALK_MOUSE   (P97793), 
DDR1_HUMAN  (Q08345), DDR1_MOUSE  (Q03146), DDR1_PANTR  (Q7YR43), 
DDR1_RAT(Q63474), DDR2_HUMAN  (Q16832), DDR2_MOUSE  (Q62371), 
HTK7_HYDVU  (Q25197), IGF1R_BOVIN (Q05688), IGF1R_HUMAN (P08069), 
IGF1R_MOUSE (Q60751), IGF1R_RAT   (P24062), IGF1R_XENLA (O73798), 
ILPR_BRALA  (O02466), INSRR_CAVPO (P14617), INSRR_HUMAN (P14616), 
INSRR_MOUSE (Q9WTL4), INSRR_RAT   (Q64716), INSR_AEDAE  (Q93105), 
INSR_DROME  (P09208), INSR_HUMAN  (P06213), INSR_MOUSE  (P15208), 
INSR_RAT(P15127), INSR_XENLA  (Q9PVZ4), LTK_DANRE   (F1QVU0), 
LTK_HUMAN   (P29376), LTK_MOUSE   (P08923), MIPR_LYMST  (Q25410), 
NTRK1_CHICK (Q91009), NTRK1_HUMAN (P04629), NTRK1_MOUSE (Q3UFB7), 
NTRK1_RAT   (P35739), NTRK2_CHICK (Q91987), NTRK2_HUMAN (Q16620), 
NTRK2_MOUSE (P15209), NTRK2_RAT   (Q63604), NTRK3_CHICK (Q91044), 
NTRK3_HUMAN (Q16288), NTRK3_MACFA (Q5IFJ9), NTRK3_MOUSE (Q6VNS1), 
NTRK3_PANTR (Q5IS37), NTRK3_PIG   (P24786), NTRK3_RAT   (Q03351), 
NTRK3_SAIBB (Q5IS82), ROR1_DROME  (Q24488), ROS1_CHICK  (P08941), 
ROS1_HUMAN  (P08922), ROS_AVISU   (P00529), RTK2_GEOCY  (P42159), 
TRK1_LYMST  (O76997)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

PTK7_HUMAN  (Q13308), PTK7_MOUSE  (Q8BKG3)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			2 sequences
			


			
IGF1R_PIG   (Q29000), INSR_MACMU  (Q28516)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
KSL1_SALMI  (C8XPS0), OST1A_ORYSJ (Q0DJC5)


				
	

	

		PDB
[Detailed view]		
		
			243 PDB
			


			1GAG; 1I44; 1IR3; 1IRK; 1JQH; 1K3A; 1M7N; 1P14; 1P4O; 1RQQ; 2AUH; 2B4S; 
			
				2OJ9; 2XB7; 2XBA; 2XP2; 2YFX; 2YHV; 2YJR; 2YJS; 2Z8C; 2ZM3; 3AOX; 3BU3; 
				3BU5; 3BU6; 3D94; 3EKK; 3EKN; 3ETA; 3F5P; 3I81; 3L9P; 3LCS; 3LCT; 3LVP; 
				3LW0; 3NW5; 3NW6; 3NW7; 3O23; 3QQU; 3V5Q; 3ZBF; 3ZOS; 4ANL; 4ANQ; 4ANS; 
				4AOJ; 4ASZ; 4AT3; 4AT4; 4AT5; 4BKJ; 4CCB; 4CCU; 4CD0; 4CKR; 4CLI; 4CLJ; 
				4CMO; 4CMT; 4CMU; 4CNH; 4CTB; 4CTC; 4D2R; 4DCE; 4F0I; 4FNW; 4FNX; 4FNY; 
				4FNZ; 4FOB; 4FOC; 4FOD; 4GT5; 4IBM; 4JOA; 4MKC; 4PMM; 4PMP; 4PMS; 4PMT; 
				4TT7; 4UXL; 4XLV; 4YMJ; 4YNE; 4YPS; 4Z55; 5A9U; 5AA8; 5AA9; 5AAA; 5AAB; 
				5AAC; 5BVK; 5BVN; 5BVO; 5BVW; 5E1S; 5FDP; 5FDX; 5FTO; 5FTQ; 5FXQ; 5FXR; 
				5H3Q; 5HHW; 5HZN; 5I8A; 5IMX; 5IUG; 5IUH; 5IUI; 5JFS; 5JFV; 5JFW; 5JFX; 
				5KMI; 5KMJ; 5KMK; 5KML; 5KMM; 5KMN; 5KMO; 5KVT; 5KZ0; 5SAU; 5SAV; 5SAW; 
				5SAX; 5SAY; 5SAZ; 5SB0; 5SB1; 5SB2; 5WR7; 6BRJ; 6BSD; 6CDT; 6D1Y; 6D1Z; 
				6D20; 6D22; 6DKB; 6DKG; 6DKI; 6DKW; 6E0R; 6EBW; 6EDL; 6FER; 6FEW; 6FEX; 
				6FIL; 6FIN; 6FIO; 6FIQ; 6GWR; 6HP9; 6IQN; 6J5L; 6JK8; 6KZC; 6KZD; 6MX8; 
				6NPT; 6NSP; 6NSS; 6PL1; 6PL2; 6PL3; 6PL4; 6PMA; 6PMB; 6PMC; 6PME; 6PXV; 
				6PXW; 6PYH; 6Y23; 7BCM; 7BE6; 7BTT; 7BW7; 7BW8; 7BWA; 7FEH; 7JY4; 7JYR; 
				7JYS; 7JYT; 7PG0; 7PG2; 7PG3; 7PG4; 7R7K; 7R7R; 7SL1; 7SL2; 7SL3; 7SL4; 
				7SL6; 7SL7; 7STH; 7STI; 7STJ; 7STK; 7TYJ; 7TYK; 7TYM; 7VKM; 7VKN; 7VKO; 
				7XAF; 7XBI; 7Z5W; 7Z5X; 8ARJ; 8DTL; 8DTM; 8DWN; 8EYR; 8EYX; 8EYY; 8EZ0; 
				8J5W; 8J5X; 8J61; 8J63; 8PYI; 8PYJ; 8PYK; 8PYL; 8PYM; 8PYN; 8U4B; 8U4C; 
				8U4E; 8VJB; 8VJC
			
			

			» more