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PROSITE entry PS00242


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General information about the entry

Entry name [info] INTEGRIN_ALPHA
Accession [info] PS00242
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-JUN-1994 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00215

Name and characterization of the entry

Description [info] Integrins alpha chain signature.
Pattern [info] 
[FYWS]-[RK]-x-G-F-F-x-R.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 64 in 64 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 11 in 11 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 82.81 %
Recall (true positives / (true positives + false negatives)) 94.64 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 53 sequences 

INA1_CAEEL  (Q03600    ), ITA1_DROME  (Q24247    ), ITA1_HUMAN  (P56199    ), 

ITA1_MOUSE  (Q3V3R4    ), ITA1_RAT    (P18614    ), ITA2B_HUMAN (P08514    ), 
ITA2B_MOUSE (Q9QUM0    ), ITA2B_PAPCY (P53711    ), ITA2_BOVIN  (P53710    ), 
ITA2_DROME  (P12080    ), ITA2_HUMAN  (P17301    ), ITA2_MOUSE  (Q62469    ), 
ITA3_BOVIN  (F1MMS9    ), ITA3_CRIGR  (P17852    ), ITA3_DROME  (O44386    ), 
ITA3_HUMAN  (P26006    ), ITA3_MOUSE  (Q62470    ), ITA4_DROME  (Q9V7A4    ), 
ITA4_HUMAN  (P13612    ), ITA4_MOUSE  (Q00651    ), ITA4_XENLA  (Q91687    ), 
ITA5_HUMAN  (P08648    ), ITA5_MOUSE  (P11688    ), ITA5_XENLA  (Q06274    ), 
ITA6_CHICK  (P26007    ), ITA6_HUMAN  (P23229    ), ITA6_MOUSE  (Q61739    ), 
ITA7_HUMAN  (Q13683    ), ITA7_MOUSE  (Q61738    ), ITA7_RAT    (Q63258    ), 
ITA8_CHICK  (P26009    ), ITA8_HUMAN  (P53708    ), ITA8_MOUSE  (A2ARA8    ), 
ITA9_HUMAN  (Q13797    ), ITA9_MOUSE  (B8JK39    ), ITAD_HUMAN  (Q13349    ), 
ITAD_MOUSE  (Q3V0T4    ), ITAD_RAT    (Q9QYE7    ), ITAE_HUMAN  (P38570    ), 
ITAE_MOUSE  (Q60677    ), ITAL_BOVIN  (P61625    ), ITAL_HUMAN  (P20701    ), 
ITAL_MOUSE  (P24063    ), ITAM_HUMAN  (P11215    ), ITAM_MOUSE  (P05555    ), 
ITAV_BOVIN  (P80746    ), ITAV_CHICK  (P26008    ), ITAV_HUMAN  (P06756    ), 
ITAV_MOUSE  (P43406    ), ITAX_HUMAN  (P20702    ), ITAX_MOUSE  (Q9QXH4    ), 
PAT2_CAEBR  (A8X3A7    ), PAT2_CAEEL  (P34446    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

ITA10_HUMAN (O75578    ), ITA11_HUMAN (Q9UKX5    ), ITA11_MOUSE (P61622    )


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			3 sequences
			


			
ITA1_CHICK  (Q90615    ), ITA5_BOVIN  (Q27977    ), ITAM_CAVPO  (P11578    )


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			11 sequences
			


			
ALT5_ALTAL  (A0A3G9H9H1), GRK1_CAEBR  (Q622Z7    ), GRK1_CAEEL  (Q09537    ), 

			
NAAT1_DROAN (B3MRS1    ), NAAT1_DROER (B3NV41    ), NAAT1_DROME (Q9W4C5    ), 
NAAT1_DROSI (B4R4T6    ), NAAT1_DROYA (B4PZQ4    ), POM1_SCHPO  (Q09690    ), 
UCSM_ACRSP  (A0A411KUQ2), Y736_HAEIN  (P44849    )


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			16 PDB
			


			1KUP; 1KUZ; 2K1A; 2K9J; 2KNC; 2L8S; 2M3E; 2MTP; 2N9Y; 6UJA; 6UJB; 6UJC; 
			
				7KN0; 7LA4; 7NWL; 7NXD
			
			

			» more