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PROSITE entry PS00242


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00242
Entry name [info] INTEGRIN_ALPHA
Accession [info] PS00242
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-JUN-1994 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00215

Name and characterization of the entry

Description [info] Integrins alpha chain signature.
Pattern [info] 
[FYWS]-[RK]-x-G-F-F-x-R.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 65 in 65 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 0
Number of false positive hits 12 in 12 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 81.54 %
Recall (true positives / (true positives + false negatives)) 94.64 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 53 sequences 

INA1_CAEEL  (Q03600), ITA1_DROME  (Q24247), ITA1_HUMAN  (P56199), 

ITA1_MOUSE  (Q3V3R4), ITA1_RAT(P18614), ITA2B_HUMAN (P08514), 
ITA2B_MOUSE (Q9QUM0), ITA2B_PAPCY (P53711), ITA2_BOVIN  (P53710), 
ITA2_DROME  (P12080), ITA2_HUMAN  (P17301), ITA2_MOUSE  (Q62469), 
ITA3_BOVIN  (F1MMS9), ITA3_CRIGR  (P17852), ITA3_DROME  (O44386), 
ITA3_HUMAN  (P26006), ITA3_MOUSE  (Q62470), ITA4_DROME  (Q9V7A4), 
ITA4_HUMAN  (P13612), ITA4_MOUSE  (Q00651), ITA4_XENLA  (Q91687), 
ITA5_HUMAN  (P08648), ITA5_MOUSE  (P11688), ITA5_XENLA  (Q06274), 
ITA6_CHICK  (P26007), ITA6_HUMAN  (P23229), ITA6_MOUSE  (Q61739), 
ITA7_HUMAN  (Q13683), ITA7_MOUSE  (Q61738), ITA7_RAT(Q63258), 
ITA8_CHICK  (P26009), ITA8_HUMAN  (P53708), ITA8_MOUSE  (A2ARA8), 
ITA9_HUMAN  (Q13797), ITA9_MOUSE  (B8JK39), ITAD_HUMAN  (Q13349), 
ITAD_MOUSE  (Q3V0T4), ITAD_RAT(Q9QYE7), ITAE_HUMAN  (P38570), 
ITAE_MOUSE  (Q60677), ITAL_BOVIN  (P61625), ITAL_HUMAN  (P20701), 
ITAL_MOUSE  (P24063), ITAM_HUMAN  (P11215), ITAM_MOUSE  (P05555), 
ITAV_BOVIN  (P80746), ITAV_CHICK  (P26008), ITAV_HUMAN  (P06756), 
ITAV_MOUSE  (P43406), ITAX_HUMAN  (P20702), ITAX_MOUSE  (Q9QXH4), 
PAT2_CAEBR  (A8X3A7), PAT2_CAEEL  (P34446)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

ITA10_HUMAN (O75578), ITA11_HUMAN (Q9UKX5), ITA11_MOUSE (P61622)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			3 sequences
			


			
ITA1_CHICK  (Q90615), ITA5_BOVIN  (Q27977), ITAM_CAVPO  (P11578)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			12 sequences
			


			
ALT5_ALTAL  (A0A3G9H9H1), GRK1_CAEBR  (Q622Z7), GRK1_CAEEL  (Q09537), 

			
NAAT1_DROAN (B3MRS1), NAAT1_DROER (B3NV41), NAAT1_DROME (Q9W4C5), 
NAAT1_DROSI (B4R4T6), NAAT1_DROYA (B4PZQ4), POM1_SCHPO  (Q09690), 
PUT2H_BORBR (A0A0H3LKV3), UCSM_ACRSP  (A0A411KUQ2), Y736_HAEIN  (P44849)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			35 PDB
			


			1KUP; 1KUZ; 2K1A; 2K9J; 2KNC; 2L8S; 2M3E; 2MTP; 2N9Y; 6UJA; 6UJB; 6UJC; 
			
				7KN0; 7LA4; 7NWL; 7NXD; 7SC4; 7SFT; 8GCD; 8GCE; 8T2U; 8T2V; 8XEI; 8XEK; 
				8XEL; 8XEN; 8XER; 8XEZ; 8XF6; 8XFG; 8XFO; 8ZJF; 9AXL; 9DEQ; 9DER
			
			

			» more