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PROSITE entry PS00248


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PURL: https://purl.expasy.org/prosite/signature/PS00248

Direct ScanProsite submission
General information about the entry

Entry name [info] NGF_1
Accession [info] PS00248
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00221

Name and characterization of the entry

Description [info] Nerve growth factor family signature.
Pattern [info] 
[GSRE]-C-[KRL]-G-[LIVT]-[DE]-x(3)-[YW]-x-S-x-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 117 in 117 different sequences
Number of true positive hits 117 in 117 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 27
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.15 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 2
Site [info] disulfide at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 117 sequences 

BDNF_ACRDU  (Q1X706), BDNF_ACRJA  (Q1X702), BDNF_AILFU  (O97759), 

BDNF_AILME  (Q6LCI5), BDNF_ANISC  (Q1X700), BDNF_ASPME  (Q1HN40), 
BDNF_BOACO  (Q1X708), BDNF_BOVIN  (Q95106), BDNF_CALRI  (Q1X6Z7), 
BDNF_CANCA  (Q1X707), BDNF_CANLF  (Q7YRB4), BDNF_CAVPO  (O70183), 
BDNF_CHABO  (Q1X6Z6), BDNF_CHICK  (P25429), BDNF_CHISR  (Q1HN42), 
BDNF_CORCI  (Q1X711), BDNF_CYLRU  (Q1X701), BDNF_CYPCA  (Q90322), 
BDNF_EPICE  (Q1X710), BDNF_ERYCC  (Q1HN34), BDNF_ERYCN  (Q1X6Z8), 
BDNF_ERYJO  (Q1HN32), BDNF_ERYJY  (Q1HN36), BDNF_EUNNO  (Q1X709), 
BDNF_EXIPL  (Q1X704), BDNF_FELCA  (Q9TST3), BDNF_HELMA  (O18753), 
BDNF_HORSE  (Q0EAB7), BDNF_HUMAN  (P23560), BDNF_LICTR  (Q1HN31), 
BDNF_LIPVE  (Q49M28), BDNF_LOXBI  (Q1HN33), BDNF_MACLB  (P25431), 
BDNF_MACMU  (Q06225), BDNF_MORSI  (Q1X703), BDNF_MOUSE  (P21237), 
BDNF_PANTR  (Q5IS78), BDNF_PIG(P14082), BDNF_PROLO  (O18755), 
BDNF_PTYMJ  (Q8QG74), BDNF_RAJCL  (P25430), BDNF_RAMSP  (Q1X6Z5), 
BDNF_RAT(P23363), BDNF_SANME  (Q1X705), BDNF_SPECI  (Q4L0Y3), 
BDNF_TROHA  (Q1X6Z9), BDNF_URSAR  (O18752), BDNF_URSTH  (Q3SAT7), 
BDNF_XENLA  (P25432), BDNF_XENUN  (Q1HN38), BDNF_XIPMA  (Q02193), 
NGFV1_AZEFE (Q2XXL6), NGFV1_DEMVE (A6MFL5), NGFV1_HOPST (Q3HXY0), 
NGFV1_NAJSP (Q5YF90), NGFV1_NOTSC (Q3HXY7), NGFV1_OXYMI (Q3HXZ1), 
NGFV1_PSEAU (Q3HXY3), NGFV1_PSETE (Q3HXY9), NGFV1_TROCA (Q3HXX8), 
NGFV2_DEMVE (A6MFL6), NGFV2_HOPST (Q3HXX9), NGFV2_NAJSP (Q5YF89), 
NGFV2_OXYMI (Q3HXZ0), NGFV2_PSEAU (Q3HXY2), NGFV2_PSETE (Q3HXY8), 
NGFV2_TROCA (Q3HXX7), NGFV3_DEMVE (A6MFL7), NGFV3_NOTSC (Q3HXY5), 
NGFV3_PSEAU (Q3HXY1), NGFV3_TROCA (Q3HXX6), NGFV4_TROCA (Q3HXX5), 
NGFV5_TROCA (Q3HXX4), NGFV_AGKCO  (B8QCG6), NGFV_BOTJR  (Q90W38), 
NGFV_BUNMU  (P34128), NGFV_CRODU  (Q9DEZ9), NGFV_CRYNI  (Q1W7Q6), 
NGFV_DABRR  (P30894), NGFV_DRYCN  (F8RKW5), NGFV_MACLB  (P25428), 
NGFV_NAJAT  (P61898), NGFV_NAJKA  (P61899), NGFV_NAJNA  (P01140), 
NGFV_OXYSC  (Q3I5F4), NGFV_PSEPO  (Q3HXY4), NGF_BOVIN   (P13600), 
NGF_CAVPO   (P19093), NGF_CHICK   (P05200), NGF_DANRE   (Q6YBR5), 
NGF_GORGO   (Q9N2F0), NGF_HUMAN   (P01138), NGF_MASNA   (P20675), 
NGF_MOUSE   (P01139), NGF_PANTR   (Q9N2F1), NGF_PIG (Q29074), 
NGF_PONPY   (Q9N2E9), NGF_RAT (P25427), NGF_SAIBB   (Q5ISB0), 
NGF_XENLA   (P21617), NGF_XIPMA   (P34129), NTF3_BOVIN  (Q08DT3), 
NTF3_CHICK  (P25433), NTF3_FELCA  (Q9TST2), NTF3_HUMAN  (P20783), 
NTF3_MOUSE  (P20181), NTF3_PIG(Q06AV0), NTF3_RAJCL  (P25434), 
NTF3_RAT(P18280), NTF3_XENLA  (P25435), NTF4_HUMAN  (P34130), 
NTF4_MACLB  (P25436), NTF4_MOUSE  (Q80VU4), NTF4_RAT(P34131), 
NTF4_XENLA  (P24727), NTF7_CYPCA  (O93474), NTF7_DANRE  (O73797)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

NGFV2_NOTSC (Q3HXY6)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			27 sequences
			


			
NGFV_BOTCO  (P0DMG7), NGFV_ECHOC  (P0DMD1), NTF3_ACRDU  (Q1X6Y9), 

			
NTF3_ACRJA  (Q1X6Y5), NTF3_ANISC  (Q1X6Y3), NTF3_ASPME  (Q1KN21), 
NTF3_BOACO  (Q1X6Z1), NTF3_CALRI  (Q1X6Y0), NTF3_CANCA  (Q1X6Z0), 
NTF3_CEREL  (Q95150), NTF3_CHABO  (Q1X6X9), NTF3_CHISR  (Q1KN23), 
NTF3_CORCI  (Q1X6Z4), NTF3_CYLRU  (Q1X6Y4), NTF3_EPICE  (Q1X6Z3), 
NTF3_ERYCC  (Q1KN16), NTF3_ERYCN  (Q1X6Y1), NTF3_ERYJO  (Q1KN12), 
NTF3_EUNNO  (Q1X6Z2), NTF3_EXIPL  (Q1X6Y7), NTF3_LICTR  (Q1KN10), 
NTF3_LOXBI  (Q1KN14), NTF3_MORSI  (Q1X6Y6), NTF3_RAMSP  (Q1X6X8), 
NTF3_SANME  (Q1X6Y8), NTF3_TROHA  (Q1X6Y2), NTF3_XENUN  (Q1KN19)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			24 PDB
			


			1B8K; 1B8M; 1B98; 1BET; 1BND; 1BTG; 1HCF; 1NT3; 1SG1; 1SGF; 1WWW; 2IFG; 
			
				3BUK; 3IJ2; 4EAX; 4EC7; 4EDW; 4EDX; 4XPJ; 4ZBN; 5JZ7; 5LSD; 6FFY; 6YW8
			
			

			» more