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PROSITE entry PS00258


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PURL: https://purl.expasy.org/prosite/signature/PS00258

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General information about the entry

Entry name [info] CALCITONIN
Accession [info] PS00258
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-JUN-1992 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00231

Name and characterization of the entry

Description [info] Calcitonin / CGRP / IAPP family signature.
Pattern [info] 
C-[SAGDN]-[STN]-x(0,1)-[SA]-T-C-[VMA]-x(3)-[LYF]-x(3)-[LYF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 42 in 42 different sequences
Number of true positive hits 42 in 42 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 6
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 87.50 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 42 sequences 

CALC1_ONCKE (P01263), CALC2_ONCGO (P69165), CALC2_ONCKE (P69067), 

CALC2_ONCNE (P69068), CALC3_ONCKI (P01265), CALCA_CANLF (Q9MYV1), 
CALCA_CHICK (P10286), CALCA_HUMAN (P06881), CALCA_MOUSE (Q99JA0), 
CALCA_PIG   (P30880), CALCA_RAT   (P01256), CALCA_SHEEP (P30881), 
CALCB_HORSE (Q9N0T3), CALCB_HUMAN (P10092), CALCB_MOUSE (Q99MP3), 
CALCB_PELRI (P31888), CALCB_PHYBI (P81564), CALCB_RAT   (P10093), 
CALC_ANGJA  (P01262), CALC_BOVIN  (P01260), CALC_CANLF  (P41547), 
CALC_CHICK  (P07660), CALC_HORSE  (Q9N0V5), CALC_HUMAN  (P01258), 
CALC_MOUSE  (P70160), CALC_PIG(P01259), CALC_RAT(P01257), 
CALC_SHEEP  (P01261), CRSP1_BOVIN (Q75V95), CRSP1_CANLF (Q75V94), 
CRSP1_CAPHI (B3IWF7), CRSP1_PIG   (Q862B1), CRSP1_SHEEP (B3IWF9), 
IAPP_CANLF  (P17716), IAPP_CAVPO  (P12966), IAPP_CRIGR  (P19890), 
IAPP_FELCA  (P12967), IAPP_HUMAN  (P10997), IAPP_MESAU  (P23442), 
IAPP_MOUSE  (P12968), IAPP_OCTDE  (P22889), IAPP_RAT(P12969)
» more

UniProtKB/Swiss-Prot
False negative sequences		 6 sequences 

CALC_AQUCT  (P0C234), CRSP2_CANLF (Q75V93), CRSP2_CAPHI (B3IWF8), 

CRSP2_PIG   (Q766Y7), CRSP3_PIG   (Q766Y6), IAPP_BOVIN  (Q28207)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

IAPP_PIG(Q29119), IAPP_RABIT  (Q07334), IAPP_SAGOE  (Q28934), 

IAPP_SHEEP  (Q28605)
» more

PDB
[Detailed view]		 62 PDB

pdb_00001bku; pdb_00001byv; pdb_00001bzb; pdb_00002g48; pdb_00002glg; pdb_00002glh; pdb_00002jxz; pdb_00002kb8; pdb_00002kj7; pdb_00002l86; pdb_00003g7v; pdb_00003g7w; pdb_00003hgz; pdb_00005k5g; pdb_00005mgq; pdb_00006e3y; pdb_00006ucj; pdb_00006uck; pdb_00006vw2; pdb_00006y1a; pdb_00006zrf; pdb_00006zrq; pdb_00006zrr; pdb_00007bg0; pdb_00007knu; pdb_00007m61; pdb_00007m62; pdb_00007m64; pdb_00007m65; pdb_00007tyf; pdb_00007tyh; pdb_00007tyi; pdb_00007tyl; pdb_00007tyo; pdb_00007tyx; pdb_00007tzf; pdb_00007ykw; pdb_00007yl0; pdb_00007yl3; pdb_00007yl7; pdb_00008awt; pdb_00008az0; pdb_00008az1; pdb_00008az2; pdb_00008az3; pdb_00008az4; pdb_00008az5; pdb_00008az6; pdb_00008az7; pdb_00008f0j; pdb_00008f0k; pdb_00008f2a; pdb_00008f2b; pdb_00008r4i; pdb_00009auc; pdb_00009gz6; pdb_00009gzp; pdb_00009gzs; pdb_00009gzt; pdb_00009gzw; pdb_00009gzx; pdb_00009gzy
» more