PROSITE entry PS00258
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00258 |
| Entry name [info] | CALCITONIN |
| Accession [info] | PS00258 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-JUN-1992 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00231 |
Name and characterization of the entry
| Description [info] | Calcitonin / CGRP / IAPP family signature. |
| Pattern [info] |
C-[SAGDN]-[STN]-x(0,1)-[SA]-T-C-[VMA]-x(3)-[LYF]-x(3)-[LYF]. |
Numerical results [info]
| Total number of hits | 42 in 42 different sequences |
| Number of true positive hits | 42 in 42 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 6 |
| Number of 'partial' sequences | 4 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 87.50 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Site [info] | disulfide at position 1 |
| Site [info] | disulfide at position 7 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
42 sequences
CALC1_ONCKE (P01263), CALC2_ONCGO (P69165), CALC2_ONCKE (P69067), CALC2_ONCNE (P69068), CALC3_ONCKI (P01265), CALCA_CANLF (Q9MYV1), CALCA_CHICK (P10286), CALCA_HUMAN (P06881), CALCA_MOUSE (Q99JA0), CALCA_PIG (P30880), CALCA_RAT (P01256), CALCA_SHEEP (P30881), CALCB_HORSE (Q9N0T3), CALCB_HUMAN (P10092), CALCB_MOUSE (Q99MP3), CALCB_PELRI (P31888), CALCB_PHYBI (P81564), CALCB_RAT (P10093), CALC_ANGJA (P01262), CALC_BOVIN (P01260), CALC_CANLF (P41547), CALC_CHICK (P07660), CALC_HORSE (Q9N0V5), CALC_HUMAN (P01258), CALC_MOUSE (P70160), CALC_PIG(P01259), CALC_RAT(P01257), CALC_SHEEP (P01261), CRSP1_BOVIN (Q75V95), CRSP1_CANLF (Q75V94), CRSP1_CAPHI (B3IWF7), CRSP1_PIG (Q862B1), CRSP1_SHEEP (B3IWF9), IAPP_CANLF (P17716), IAPP_CAVPO (P12966), IAPP_CRIGR (P19890), IAPP_FELCA (P12967), IAPP_HUMAN (P10997), IAPP_MESAU (P23442), IAPP_MOUSE (P12968), IAPP_OCTDE (P22889), IAPP_RAT(P12969)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
6 sequences
CALC_AQUCT (P0C234), CRSP2_CANLF (Q75V93), CRSP2_CAPHI (B3IWF8), CRSP2_PIG (Q766Y7), CRSP3_PIG (Q766Y6), IAPP_BOVIN (Q28207)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
4 sequences
IAPP_PIG(Q29119), IAPP_RABIT (Q07334), IAPP_SAGOE (Q28934), IAPP_SHEEP (Q28605)» more |
| PDB [Detailed view] |
55 PDB
1BKU; 1BYV; 1BZB; 2G48; 2GLG; 2GLH; 2JXZ; 2KB8; 2KJ7; 2L86; 3G7V; 3G7W; 3HGZ; 5K5G; 5MGQ; 6E3Y; 6UCJ; 6UCK; 6VW2; 6Y1A; 6ZRF; 6ZRQ; 6ZRR; 7BG0; 7KNU; 7M61; 7M62; 7M64; 7M65; 7TYF; 7TYH; 7TYI; 7TYL; 7TYO; 7TYX; 7TZF; 7YKW; 7YL0; 7YL3; 7YL7; 8AWT; 8AZ0; 8AZ1; 8AZ2; 8AZ3; 8AZ4; 8AZ5; 8AZ6; 8AZ7; 8F0J; 8F0K; 8F2A; 8F2B; 8R4I; 9AUC » more |