PROSITE entry PS00268

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00268
Entry name [info]	CECROPIN
Accession [info]	PS00268
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00241

Name and characterization of the entry

Description [info]	Cecropin family signature.
Pattern [info]	W-x(0,2)-[KDN]-{Q}-{L}-K-[KRE]-[LI]-E-[RKN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	78 in 78 different sequences
Number of true positive hits	58 in 58 different sequences
Number of 'unknown' hits	0
Number of false positive hits	20 in 20 different sequences
Number of false negative sequences	15
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	74.36 %
Recall (true positives / (true positives + false negatives))	79.45 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	58 sequences CE3D_HYPCU (P50720), CE3E_HYPCU (P50721), CE3F_HYPCU (P50722), CE3G_HYPCU (P50723), CEC1_CERCA (Q06589), CEC1_DROVI (Q94557), CEC2_CERCA (Q06590), CEC2_DROVI (Q94990), CEC2_MANSE (P14662), CEC3_MANSE (P14663), CEC4_BOMMO (P14666), CEC4_MANSE (P14664), CEC5_MANSE (P14665), CECA1_DROMA (P81685), CECA1_DROME (C0HKQ7), CECA1_DROSE (P81688), CECA1_DROSI (O61272), CECA2_DROME (C0HKQ8), CECA2_DROYA (O61281), CECA_BOMMO (Q27239), CECA_HELVI (P83413), CECA_HYACE (P01507), CECA_SPOLT (Q9XZG9), CECA_TRINI (P50724), CECB_ANOGA (Q8MUF4), CECB_ANTPE (P01509), CECB_BOMMO (P04142), CECB_DROMA (P81686), CECB_DROME (P14956), CECB_DROSE (P67791), CECB_DROSI (P67792), CECB_HELVI (P83414), CECB_HYACE (P01508), CECB_SPOLT (Q9XZH0), CECC_DROER (P84222), CECC_DROMA (P84019), CECC_DROME (O16829), CECC_DROOR (P84223), CECC_DROSE (P84020), CECC_DROSI (P84021), CECC_DROTE (P84225), CECC_DROTK (P84224), CECC_DROYA (P84226), CECC_HELVI (P83415), CECD_ANTPE (P01511), CECD_HYACE (P01510), CECE_BOMMO (P48821), CECP1_ASCSU (P14661), CECP2_ASCSU (Q5H7N6), CECP3_ASCSU (Q5H7N5), CECP4_ASCSU (Q5H7N4), CEC_GALME (A0A6J1WQD0), CEC_GLOMM (P83403), CEC_OIKKI (P83420), SRX1A_SARPE (P08375), SRX1B_SARPE (P08376), SRX1C_SARPE (P08377), SRX1D_SARPE (P18312) » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	15 sequences CECA1_AEDAL (P81417), CECA2_AEDAL (Q963B0), CECA_AEDAE (P82592), CECA_ANOGA (P82290), CECA_CULPP (Q86PR6), CECB1_AEDAL (Q9Y0Y0), CECB1_CULPP (Q86PR5), CECB2_AEDAL (Q963A9), CECB2_CULPP (Q86PR4), CECC1_AEDAL (Q9Y0X9), CECC2_AEDAL (Q963A8), CECC_ANOGA (Q8MUF3), CECD_BOMMO (O76146), CECD_GALME (P85210), DFP4_LONON (Q5MGD8) » more
UniProtKB/Swiss-Prot False positive sequences	20 sequences AROK_METCA (Q60BY3), CE05_ECOLX (Q47500), CE10_ECOLX (Q47125), CS13A_LEPSD (P0DOC6), CYDA_BACSU (P94364), DTD_LACAC (Q5FKI6), FUSA_STRPN (A0A0H2URD6), HMCN1_HUMAN (Q96RW7), MUTA_STRVG (Q05064), PI5K5_ARATH (Q9SLG9), PILR3_ARATH (O65679), PROS_HETIT (W4JX79), PRP5_YARLI (Q6CCZ1), RAD50_THEVO (P58302), RL3_METJA (P54014), RRF_LACP7 (A9KMX5), SPO22_YEAST (P40511), TPCD_COCH5 (M2T7Z1), Y3293_ARATH (Q9M8T5), YL339_YEAST (O94085) » more
PDB [Detailed view]	3 PDB 2N92; 7DEH; 7VOZ