PROSITE entry PS00279
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General information about the entry
| Entry name [info] | MACPF_1 |
| Accession [info] | PS00279 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE; 03-MAY-2023 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00251 |
Name and characterization of the entry
| Description [info] | Membrane attack complex/perforin (MACPF) domain signature. |
| Pattern [info] |
Y-x(6)-[FY]-G-T-H-[FY]. |
Numerical results [info]
| Total number of hits | 30 in 30 different sequences |
| Number of true positive hits | 30 in 30 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 25 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 54.55 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
30 sequences
CO6_BOVIN (Q29RU4 ), CO6_HUMAN (P13671 ), CO6_PANTR (P61134 ), CO6_PONPY (P61135 ), CO6_RAT (Q811M5 ), CO7_BOVIN (Q29RQ1 ), CO7_HUMAN (P10643 ), CO7_PIG (Q9TUQ3 ), CO7_PONAB (Q5RAD0 ), CO8A_HUMAN (P07357 ), CO8A_MOUSE (Q8K182 ), CO8A_RABIT (P98136 ), CO8B_HUMAN (P07358 ), CO8B_MOUSE (Q8BH35 ), CO8B_ONCMY (Q90X85 ), CO8B_PAROL (Q9PVW7 ), CO8B_RAT (P55314 ), CO9_BOVIN (Q3MHN2 ), CO9_HORSE (P48770 ), CO9_HUMAN (P02748 ), CO9_MOUSE (P06683 ), CO9_ONCMY (P06682 ), CO9_RABIT (P48747 ), CO9_RAT (Q62930 ), CO9_TAKRU (P79755 ), PERF_HUMAN (P14222 ), PERF_MOUSE (P10820 ), PERF_RAT (P35763 ), PV21_POMCA (P0C8G6 ), PV21_POMMA (P0DQO9 )» more
|
| UniProtKB/Swiss-Prot False negative sequences |
25 sequences
BRNP1_BOVIN (Q5E9L2 ), BRNP1_CHICK (Q7ZZR3 ), BRNP1_HUMAN (O60477 ), BRNP1_MOUSE (Q920P3 ), BRNP1_RAT (Q925T8 ), BRNP2_HUMAN (Q9C0B6 ), BRNP2_MOUSE (Q6DFY8 ), BRNP2_PONAB (Q5RDR5 ), BRNP2_RAT (Q8K1M8 ), BRNP3_HUMAN (Q76B58 ), BRNP3_MOUSE (Q499E0 ), BRNP3_RAT (Q8K1M7 ), CAD1_ARATH (Q9C7N2 ), CO8B_RABIT (P98137 ), MACP1_ARATH (Q8L612 ), MACP2_ARATH (Q9STW5 ), MPEG1_BOVIN (Q2KJC3 ), MPEG1_HUMAN (Q2M385 ), MPEG1_MOUSE (A1L314 ), MPEG1_PONAB (Q5RBP9 ), MPEG1_RAT (Q9WV57 ), NSL1_ARATH (Q9SGN6 ), TX60A_ACTVL (Q76DT2 ), TX60A_PHYSE (P58911 ), TX60B_PHYSE (P58912 )» more |
| PDB [Detailed view] |
15 PDB
2QQH; 2RD7; 3NSJ; 3OJY; 3T5O; 4A5W; 4E0S; 5FMW; 6CXO; 6DLW; 6H03; 6H04; 7NYC; 7NYD; 7PAG » more |