PROSITE entry PS00280
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Direct ScanProsite submission
General information about the entry
Entry name [info] | BPTI_KUNITZ_1 |
Accession [info] | PS00280 |
Entry type [info] | PATTERN |
Date [info] |
01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC00252 |
Name and characterization of the entry
Description [info] | Pancreatic trypsin inhibitor (Kunitz) family signature. |
Pattern [info] |
F-x(2)-{I}-G-C-x(6)-[FY]-x(5)-C. |
Numerical results [info]
Total number of hits | 397 in 330 different sequences |
Number of true positive hits | 391 in 324 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 6 in 6 different sequences |
Number of false negative sequences | 68 |
Number of 'partial' sequences | 22 |
Precision (true positives / (true positives + false positives)) | 98.49 % |
Recall (true positives / (true positives + false negatives)) | 85.19 % |
Comments [info]
Taxonomic range [info] | Eukaryotes |
Maximum number of repetitions [info] | 11 |
Site [info] | disulfide at position 5 |
Site [info] | disulfide at position 9 |
Version [info] | 2 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
324 sequences
3API_HETMG (C0HK72), 3BPI_HETMG (C0HK73), 3CPI_HETMG (C0HK74), 3DPD_HETMG (A0A3G2FQK2), A4_CAVPO(Q60495), A4_HUMAN(P05067), A4_MACFA(P53601), A4_MACMU(P29216), A4_MOUSE(P12023), A4_PANTR(Q5IS80), A4_PIG (P79307), A4_RAT (P08592), A4_SAISC(Q95241), A4_TAKRU(O93279), AMBP_BOVIN (P00978), AMBP_HUMAN (P02760), AMBP_MERUN (Q62577), AMBP_MESAU (Q60559), AMBP_MOUSE (Q07456), AMBP_PIG(P04366), AMBP_PLEPL (P36992), AMBP_RAT(Q64240), ANIS1_ANISI (Q7Z1K3), APLP2_HUMAN (Q06481), APLP2_RAT (P15943), ATPI1_ACTTE (A0A6P8HC43), BMTI6_RHIMP (P83606), BMTIA_RHIMP (P83609), BPT1_BOVIN (P00974), BPT2_BOVIN (P04815), CO6A3_CHICK (P15989), CO6A3_HUMAN (P12111), CO7A1_HUMAN (Q02388), CO7A1_MOUSE (Q63870), COSA1_HUMAN (Q2UY09), COSA1_MOUSE (Q2UY11), CRPTI_RHIMP (P81162), CSTI_BOMMO (P81902), ELAC_NOTEU (O62845), ELAC_TRIVU (Q29143), EPPI_HUMAN (O95925), EPPI_MACMU (Q9BDL1), EPPI_MOUSE (Q9DA01), EPPI_RAT(D4A2Z2), HTIB_MANSE (P26227), IATR_CAPHI (P62756), IATR_HORSE (P04365), IATR_SHEEP (P62757), IBPC_BOVIN (P00976), IBPI_TACTR (P16044), IBPS_BOVIN (P00975), IBP_CARCR (P00993), IMAP_DROFU (P11424), IRCPI_IXORI (Q9GP15), ISC1_BOMMO (P10831), ISC2_BOMMO (P10832), ISC3_BOMMO (P07481), ISIK_HELPO (P00994), ISPI2_GALME (P81906), IVBI3_HOPST (B5L5R6), IVBI4_NOTSC (B5L5R4), IVBI4_PSEPO (B5L5R0), IVBI5_PSEPO (B5L5R1), IVBI_AUSSU (B5L5M7), IVBS5_OXYSC (B5L5Q3), KCP1_PINMA (P86959), KCP1_PINMG (H2A0M2), KCP2_PINMG (H2A0N1), KCP3_PINMA (P86964), KCP3_PINMG (H2A0N5), KCP4_PINMG (H2A0N9), KCP5_PINMG (H2A0P0), KCP_HALAI (P86733), KUN1_TABYA (C1IBY4), KUN2_RHIHE (I6VXS1), KUN2_TABYA (C8YJ94), KUN3_TABYA (C8YJ95), KUN4_TABYA (C8YJ96), KUN5_TABYA (C8YJ97), KUNIG_RHIMP (Q8WPI3), KUNIH_RHIMP (Q8WPI2), KUNI_AMBHE (Q5VJG2), KUN_HAELO (B6ZIW0), MAMB1_DENAN (A0A1Z0YU59), MAMB2_DENVI (C0HLA5), MAMB3_DENPO (C0HLA6), MAMB4_DENVI (C0HLA7), MAMB5_DENJA (C0HLA8), MAMB6_DENVI (C0HLA9), MAMB7_DENPO (P00983), MAMB9_DENVI (C0HLB0), MCPI_MELCP (P82968), PCPI_SABMA (P84875), PPN1_CAEEL (O76840), PPN_DROME (Q868Z9), PPN_HUMAN (O95428), PPN_MOUSE (Q9EPX2), SBPI_SARBU (P26228), SPIT1_HUMAN (O43278), SPIT1_MOUSE (Q9R097), SPIT2_HUMAN (O43291), SPIT2_MOUSE (Q9WU03), SPIT3_HUMAN (P49223), SPIT4_MOUSE (Q9D263), TD1A_HADIN (A0A1D0BND9), TFPI1_HUMAN (P10646), TFPI1_MACMU (Q28864), TFPI1_MOUSE (O54819), TFPI1_RABIT (P19761), TFPI1_RAT (Q02445), TFPI2_BOVIN (Q7YRQ8), TFPI2_HUMAN (P48307), TFPI2_MOUSE (O35536), TKDP1_BOVIN (Q28201), TKDP1_SHEEP (Q29428), UPTI_PIG(Q29100), VKBH2_BUNCA (Q8AY45), VKT11_CYRSC (B2ZBB6), VKT11_HOFGE (P0C8W3), VKT12_DENAN (P0DMJ6), VKT12_MESMA (P0DJ47), VKT16_DRYCN (F8J2F4), VKT17_CYRHA (P0DJ66), VKT18_DRYCN (F8J2F6), VKT19_ANOSM (Q589G4), VKT1A_ANEVI (P0DN06), VKT1A_CYRSC (P68425), VKT1L_BUNMU (B4ESA2), VKT1_ANESU (Q9TWG0), VKT1_ANTAF (P81547), VKT1_ANTEL (P86862), VKT1_ARAVE (Q8T3S7), VKT1_AUSSU (B5KL38), VKT1_BITGA (Q6T6T5), VKT1_CRYNI (B5KF95), VKT1_DABRR (Q2ES50), VKT1_DEMVE (A6MFL1), VKT1_HOPST (B5KF94), VKT1_NOTSC (Q6ITB3), VKT1_OXYMI (Q6ITB5), VKT1_OXYSC (Q6ITB7), VKT1_PALCA (P0DQQ9), VKT1_PHIOL (A7X3V7), VKT1_PSERS (E7FL11), VKT1_PSETT (Q90WA1), VKT1_STIHL (P31713), VKT1_TELDH (A7X3V4), VKT1_TRILK (W4VSH9), VKT1_TROCA (Q6ITB0), VKT1_VIPAA (P00991), VKT1_WALAE (C1IC50), VKT27_CYRSC (P0DJ82), VKT28_DRYCN (F8J2F3), VKT2B_RADCR (B2G331), VKT2C_RADCR (C0HJF4), VKT2D_RADCR (C0HJF3), VKT2E_RADCR (P0DMJ5), VKT2F_RADCR (C0HJU6), VKT2G_RADCR (C0HJU7), VKT2H_RADCR (P0DL86), VKT2I_RADCR (A0A6B7FBD3), VKT2J_RADCR (A0A6B7FA07), VKT2K_RADCR (A0A6B7FEJ3), VKT2L_BUNMU (B4ESA3), VKT2M_RADCR (P0DV03), VKT2N_RADCR (P0DV04), VKT2O_RADCR (P0DV05), VKT2P_RADCR (P0DV06), VKT2_ANESU (Q9TWF9), VKT2_ANTAF (P81548), VKT2_AUSSU (B5KL39), VKT2_BITGA (Q6T6S5), VKT2_CRYNI (B5KF96), VKT2_DABSI (P00990), VKT2_DEMVE (A6MFL2), VKT2_HEMHA (P00985), VKT2_HOPST (B5L5R7), VKT2_NAJNI (P00986), VKT2_NOTSC (Q6ITB2), VKT2_OXYMI (Q6ITB4), VKT2_OXYSC (Q6ITB6), VKT2_PALCA (P0DQR0), VKT2_PIMHY (Q8T0W4), VKT2_PSEAU (Q6ITC0), VKT2_PSEPO (B5G6G6), VKT2_PSERS (E7FL12), VKT2_PSETT (Q90WA0), VKT2_STIHL (P81129), VKT2_TROCA (B5KL33), VKT2_WALAE (C1IC52), VKT31_MESMA (P0DJ50), VKT39_CYRSC (P0DMJ1), VKT3A_ACTEQ (P0DMW6), VKT3B_ACTEQ (P0DMW7), VKT3C_ACTEQ (P0DMJ2), VKT3L_BUNMU (B4ESA4), VKT3_ANESU (Q9TWF8), VKT3_ANTAF (P0DMX0), VKT3_AUSSU (B5KL40), VKT3_BITGA (Q6T269), VKT3_CRYNI (B5KL34), VKT3_DABRR (Q2ES48), VKT3_DEMVE (A6MFL3), VKT3_NOTSC (B5KL32), VKT3_OXYMI (B5KL27), VKT3_OXYSC (B5KL29), VKT3_PALCA (P0DQR1), VKT3_PSEAU (Q6ITB9), VKT3_PSEPO (B5KL31), VKT3_PSERS (E7FL13), VKT3_PSETT (Q90W99), VKT3_STIHA (B1B5I8), VKT3_VIPAA (P00992), VKT3_WALAE (C1IC51), VKT4_ANEVI (P0DN07), VKT4_AUSSU (B5KL41), VKT4_CRYNI (B5KL35), VKT4_CYRSC (P0DJ76), VKT4_DABRR (Q2ES47), VKT4_DEMVE (A6MFL4), VKT4_OXYMI (B5KL28), VKT4_OXYSC (B5KL30), VKT4_PSEAU (Q6ITB8), VKT4_PSETT (Q90W98), VKT4_WALAE (C1IC53), VKT52_ANESU (P10280), VKT53_ANEVI (P0DN08), VKT5_ANEVI (P0DN09), VKT5_BUNFL (D5J9Q8), VKT5_CRYNI (B5KL36), VKT5_DABRR (Q2ES46), VKT5_DEMVE (A6MGX9), VKT5_OXYMI (B5L5Q6), VKT5_PSEAU (B5L5Q8), VKT5_PSETT (Q90W97), VKT6_ANEVI (P0DN10), VKT6_CRYNI (B5KL37), VKT6_PSETT (Q90W96), VKT7_ANEVI (P0DN11), VKT7_DEMVE (A6MGY1), VKT7_PSETT (B5L5Q1), VKT87_DRYCN (F8J2F5), VKT8_ANEVI (P0DN12), VKT9_ANEVI (P0DN13), VKT9_BUNFA (P25660), VKTA_ANEVI (P0DN14), VKTA_BUNCA (Q8AY43), VKTB1_DABSI (A8Y7P1), VKTB2_DABSI (A8Y7P2), VKTB3_DABSI (A8Y7P3), VKTB4_DABSI (A8Y7P4), VKTB5_DABSI (A8Y7P5), VKTB6_DABSI (A8Y7P6), VKTB7_DABSI (A8Y7P0), VKTB_ANEVI (P0DN15), VKTB_BUNCA (Q8AY42), VKTC1_DABSI (A8Y7N4), VKTC2_DABSI (A8Y7N5), VKTC3_DABSI (A8Y7N6), VKTC4_DABSI (A8Y7N7), VKTC5_DABSI (A8Y7N8), VKTC6_DABSI (A8Y7N9), VKTCI_NAJNA (P19859), VKTCI_OPHHA (P82966), VKTCT_OPHHA (B6RLX2), VKTC_ANEVI (P0DN16), VKTC_BUNCA (Q8AY41), VKTD_ANEVI (P0DN17), VKTE_ANEVI (P0DN18), VKTE_DENPO (P00984), VKTF_ANEVI (P0DN19), VKTG_ANEVI (P0DN20), VKTH1_BUNFA (B2KTG2), VKTH1_BUNMU (P00987), VKTH1_DENPO (P00979), VKTH1_PSEAU (Q6ITC1), VKTH2_BUNFA (B2KTG3), VKTH2_BUNMU (P00989), VKTH3_BUNCA (Q75S50), VKTH3_BUNMU (Q9W728), VKTH4_BUNCA (Q75S49), VKTH4_BUNMU (Q1RPT0), VKTH5_BUNMU (Q1RPS9), VKTH6_BUNMU (Q1RPS8), VKTH7_BUNCA (Q8AY44), VKTH7_BUNMU (Q0PL65), VKTHA_DENAN (P00980), VKTHB_BUNCA (Q8AY46), VKTHB_BUNFL (Q7T2Q6), VKTHC_DENAN (P81658), VKTHD_DENAN (P00982), VKTHE_DENAN (Q7LZE3), VKTHK_DENPO (P00981), VKTI1_ANTFU (P0DMJ3), VKTI3_ANTFU (P0DMJ4), VKTK1_DABRR (H6VC05), VKTK2_DABRR (H6VC06), VKTRE_DENAN (Q7LZS8), VKTTI_NAJNA (P20229), VKT_AUSLA (B2BS84), VKT_BOMIG (G3LH89), VKT_BOMTE (D8KY58), VKT_BUNFA (B2KTG1), VKT_ERIMA (P24541), VKT_MACLN (I2G9B4), VKT_NAJAT (Q5ZPJ7), VKT_OXYSC (B7S4N9), VKT_PSEPC (C0HLB2), VKT_PSEPO (Q6ITB1), VKT_SISCA (A5X2X1), VKT_VIPNI (E5AJX3), VKT_VIPRE (P0DKL8), WFC6A_MOUSE (Q3UW55), WFC6B_MOUSE (F6ULY1), WFDC8_HUMAN (Q8IUA0), WFDC8_MOUSE (Q4KUS1), WFKN1_HUMAN (Q96NZ8), WFKN1_MOUSE (Q8R0S6), WFKN1_RAT (P0C5J5), WFKN2_BOVIN (Q08E66), WFKN2_HUMAN (Q8TEU8), WFKN2_MOUSE (Q7TQN3), WFKN_DANRE (Q6NUX0), YN81_CAEEL (Q03610)» more
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UniProtKB/Swiss-Prot False negative sequences |
68 sequences
A4_TETFL(O73683), AXO_DROME (M9PE65), BLI5_CAEEL (O62247), BLI5_HAECO (D3GGZ8), HA11_HYAAI (A0A1Q1NL17), IRSPI_IXORI (W6HZ31), IXOSP_IXOSC (Q964Q0), KUN1_RHIHE (D9IFL3), KUNI_ORNKA (Q8WPG5), KUNI_ORNMO (P56409), KUNP1_ARGMO (Q09JW4), KUNP2_ARGMO (Q09JW3), SPIT4_HUMAN (Q6UDR6), TAP_ORNMO (P17726), VKT13_CYRSC (P0DJ79), VKT1A_CONCL (D2Y488), VKT1B_CONCL (D2Y489), VKT1C_CONCL (D2Y490), VKT1D_CONCL (D2Y491), VKT21_LYCMC (P0DJ46), VKT22_CYRSC (P0DJ80), VKT22_LYCMC (P0DJ45), VKT23_LYCMC (P0DJ48), VKT24_CYRSC (P0DJ81), VKT24_MESMA (P0DJ49), VKT2A_RADCR (P16344), VKT2_CYRHA (D2Y2F3), VKT2_CYRSC (P0DJ75), VKT2_DABRR (Q2ES49), VKT31_CYRHA (P0DJ64), VKT33_CYRSC (B2ZBB8), VKT34_CYRHA (P0DJ67), VKT35_CYRHA (P0DJ71), VKT40_CYRSC (P0DJ84), VKT45_CYRHA (P0DJ68), VKT45_CYRSC (P0DJ85), VKT4_CYRHA (D2Y2F5), VKT52_CYRHA (P0DJ69), VKT53_CYRHA (P0DJ70), VKT68_CYRHA (P0DJ72), VKT6_CYRSC (P0DJ78), VKT74_CYRHA (P0DJ73), VKT76_CYRHA (P0DJ74), VKT7_CYRHA (P0DJ65), VKTA1_CYRHA (D2Y2C2), VKTA_MICTN (G9I929), VKTB1_CONBU (P0CY85), VKTC1_CYRHA (D2Y2F4), VKTE1_CYRHA (D2Y2F6), VKTF1_CYRHA (D2Y2F7), VKTG1_CYRHA (D2Y2F8), VKTG6_CYRSC (B2ZBB9), VKTG9_CYRSC (B2ZBC0), VKTH1_CYRHA (D2Y2F9), VKTI1_CYRHA (D2Y2G0), VKTJ1_CYRHA (D2Y2G1), VKTK1_CYRHA (D2Y2G2), VKTL1_CYRHA (D2Y2Q1), VKTM1_CYRHA (D2Y2Q2), VKTN1_CYRHA (D2Y2Q5), VKTO1_CYRHA (D2Y2Q6), VKTP1_CYRHA (D2Y2Q7), VKTQ1_CYRHA (D2Y2Q8), VKTR1_CYRHA (D2Y2Q9), VKTS1_CONST (P0C1X2), VKT_VESBI (C0LNR2), WFDC6_HUMAN (Q9BQY6), YL15_CAEEL (Q11101)» more |
UniProtKB/Swiss-Prot 'Partial' sequences |
22 sequences
BMTI2_RHIMP (P83603), BMTI3_RHIMP (P83604), BMTI4_RHIMP (P83605), BMTID_RHIMP (P83607), HTIA_MANSE (P26226), TIQ2_RHISA (P84554), TIQ7_RHISA (P84555), TIS5_RHISA (P84556), VKT10_DABSI (P85041), VKT25_CYRHA (P0CH75), VKT2L_RADCR (P0DV02), VKT33_ACTEQ (P0DMW8), VKT34_ACTEQ (P0DMW9), VKTC8_DABSI (P85039), VKTC9_DABSI (P85040), VKTG1_MICPY (P0CAR0), VKTH1_BUNCA (P84471), VKTH2_BUNCA (P84473), VKTH8_BUNCA (P84470), VKT_MICAT (P0DM47), VKT_OXYMI (P0DJ63), VT2K_RADCR (P0DV07)» more |
UniProtKB/Swiss-Prot False positive sequences |
6 sequences
AB41G_ORYSJ (Q8GU83), LRIT2_HUMAN (A6NDA9), SSPO_HUMAN (A2VEC9), TGB3_BNYVS (Q65676), TNFA_TUPTA (Q539C2), WAKLN_ARATH (Q0WNY5)» more |
PDB [Detailed view] |
159 PDB
1AAP; 1ADZ; 1B0C; 1BF0; 1BHC; 1BIK; 1BPI; 1BPT; 1BRB; 1BRC; 1BTH; 1BTI; 1BUN; 1BZ5; 1BZX; 1CA0; 1CBW; 1CO7; 1D0D; 1DEM; 1DEN; 1DTK; 1DTX; 1EAW; 1EJM; 1F5R; 1F7Z; 1FAK; 1FY8; 1G6X; 1IRH; 1JC6; 1K6U; 1KNT; 1KTH; 1KUN; 1LD5; 1MTN; 1NAG; 1OA5; 1OA6; 1P2I; 1P2J; 1P2K; 1P2M; 1P2N; 1P2O; 1P2Q; 1PIT; 1QLQ; 1SHP; 1T7C; 1T8L; 1T8M; 1T8N; 1T8O; 1TAW; 1TFX; 1TPA; 1UUA; 1UUB; 1YC0; 1YKT; 1ZJD; 1ZR0; 2DDI; 2DDJ; 2FI4; 2FTL; 2FTM; 2HEX; 2IJO; 2JOT; 2KAI; 2KNT; 2M99; 2ODY; 2PTC; 2R9P; 2RA3; 2TGP; 2TPI; 3BTD; 3BTE; 3BTF; 3BTG; 3BTH; 3BTK; 3BTM; 3BTQ; 3BTT; 3BTW; 3BYB; 3D65; 3FP6; 3FP7; 3FP8; 3GYM; 3L33; 3LDI; 3LDJ; 3LDM; 3M7Q; 3OFW; 3OTJ; 3P92; 3P95; 3T62; 3TGI; 3TGJ; 3TGK; 3TPI; 3U1J; 3UIR; 3UOU; 4BD9; 4BNR; 4BQD; 4DG4; 4DTG; 4ISL; 4ISN; 4ISO; 4PTI; 4TPI; 4U30; 4U32; 4WWY; 4WXV; 4Y0Y; 4Y0Z; 4Y10; 4Y11; 5C67; 5EZD; 5H7V; 5JBT; 5M4V; 5NMV; 5PTI; 5YV7; 5YVU; 5YW1; 5ZJ3; 6A5I; 6BX8; 6F1F; 6GFI; 6KZF; 6PTI; 7PH1; 7QIQ; 7QIR; 7QIS; 7QIT; 7V1N; 8OTF; 8PTI; 9PTI » more |