PROSITE entry PS00282
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Direct ScanProsite submission
General information about the entry
Entry name [info] | KAZAL_1 |
Accession [info] | PS00282 |
Entry type [info] | PATTERN |
Date [info] |
01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC00254 |
Name and characterization of the entry
Description [info] | Kazal serine protease inhibitors family signature. |
Pattern [info] |
C-x(4)-{C}-x(2)-C-x-{A}-x(4)-Y-x(3)-C-x(2,3)-C. |
Numerical results [info]
Total number of hits | 245 in 216 different sequences |
Number of true positive hits | 243 in 214 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 2 in 2 different sequences |
Number of false negative sequences | 65 |
Number of 'partial' sequences | 0 |
Precision (true positives / (true positives + false positives)) | 99.18 % |
Recall (true positives / (true positives + false negatives)) | 78.90 % |
Comments [info]
Taxonomic range [info] | Eukaryotes |
Maximum number of repetitions [info] | 7 |
Site [info] | disulfide at position 1 |
Site [info] | disulfide at position 5 |
Site [info] | disulfide at position 11 |
Site [info] | disulfide at position 13 |
Version [info] | 1 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
214 sequences
AGA_ANOGA (Q7Q3J5), DPGN_DIPMA (O96790), IAC1_BOVIN (P01000), IACA_PIG(P00999), IACS_PIG(P26461), IBD3_HIRME (P09865), ICHY_CAIMO (P83039), IKP1_PHYSA (P83578), IKP2_PHYSA (P83579), IMSP6_RUDPH (P86987), IOV7_CHICK (P10184), IOVO_ACRVU (P68469), IOVO_AEPAR (P52241), IOVO_AFRCO (P52258), IOVO_AIXGA (P68144), IOVO_AIXSP (P68145), IOVO_ALECH (P68146), IOVO_ALERU (P68147), IOVO_ALOAE (P68148), IOVO_ANACA (P68149), IOVO_ANAPL (P68150), IOVO_ANHNO (P05565), IOVO_ANSAN (P68389), IOVO_ANSCA (P68394), IOVO_ANSIN (P68437), IOVO_ANSSE (P05567), IOVO_ANTVI (P68381), IOVO_ANTVP (P68382), IOVO_AQUAU (P68376), IOVO_ARBTO (P05601), IOVO_ARGAR (P05608), IOVO_AYTAM (P68391), IOVO_BALPA (P52239), IOVO_BAMTH (P52259), IOVO_BONUM (P05585), IOVO_BRACA (P68393), IOVO_BUGCA (P68383), IOVO_CALCC (P68387), IOVO_CALGM (P68388), IOVO_CALSC (P05589), IOVO_CALSP (P05588), IOVO_CARPF (P52265), IOVO_CARRE (P05616), IOVO_CASBE (P62336), IOVO_CASCA (P62337), IOVO_CATWA (P67957), IOVO_CENUR (P67945), IOVO_CERNO (P05575), IOVO_CHACH (P67887), IOVO_CHATO (P67888), IOVO_CHICK (P01005), IOVO_CHLPI (P68151), IOVO_CHRAM (P68128), IOVO_CHRPC (P68127), IOVO_CHRRI (P68386), IOVO_CIRAE (P05579), IOVO_COLMD (P52244), IOVO_COLVI (P05591), IOVO_CORAL (P52243), IOVO_COSCO (P05571), IOVO_COTDE (P05600), IOVO_COTJA (P01003), IOVO_CROAU (P67951), IOVO_CROCS (P52245), IOVO_CROMA (P67952), IOVO_CYACY (P68152), IOVO_CYGAT (P68129), IOVO_CYGOL (P68130), IOVO_CYRMO (P05592), IOVO_DACNO (P05617), IOVO_DENAC (P67890), IOVO_DENAR (P67889), IOVO_DENAU (P67891), IOVO_DENBI (P67892), IOVO_DENEY (P05569), IOVO_DENVD (P05570), IOVO_DRONO (P05560), IOVO_EUDEL (P05562), IOVO_FRAFR (P05597), IOVO_FRAPO (P05598), IOVO_FULAT (P68378), IOVO_GALAS (P52266), IOVO_GALCH (P68379), IOVO_GALVA (P52267), IOVO_GEOCA (P05615), IOVO_GRUJA (P68380), IOVO_GUIGU (P52246), IOVO_GUTPU (P52260), IOVO_GYPCO (P68374), IOVO_HAEME (P52242), IOVO_HALAL (P52268), IOVO_HALIN (P05577), IOVO_LAGLU (P67961), IOVO_LARMA (P68385), IOVO_LEIOC (P05581), IOVO_LEUAL (P67940), IOVO_LOPBU (P52261), IOVO_LOPCU (P68154), IOVO_LOPDI (P67893), IOVO_LOPED (P67953), IOVO_LOPIG (P67894), IOVO_LOPIM (P67950), IOVO_LOPLE (P52262), IOVO_LOPNY (P67954), IOVO_LOPSP (P68153), IOVO_LOPSW (P67955), IOVO_MEGFR (P05580), IOVO_MELGA (P68390), IOVO_MELOE (P68436), IOVO_NECMO (P68377), IOVO_NEOJU (P68155), IOVO_NETRU (P68392), IOVO_NOTCI (P05561), IOVO_NOTPE (P52248), IOVO_NUMME (P68468), IOVO_NYCNY (P05566), IOVO_OPIHO (P52249), IOVO_OREPI (P05587), IOVO_ORTVE (P05582), IOVO_OXYJA (P68131), IOVO_OXYVI (P68132), IOVO_PAVCR (P05609), IOVO_PAVMU (P52263), IOVO_PELCO (P05595), IOVO_PENJC (P67895), IOVO_PENSU (P67896), IOVO_PERPE (P05599), IOVO_PHACO (P68470), IOVO_PHASU (P05564), IOVO_PHAVE (P68471), IOVO_PIPPP (P05584), IOVO_PODST (P52264), IOVO_POLBI (P05607), IOVO_POLNP (P52250), IOVO_POLRA (P68375), IOVO_PTEAF (P05594), IOVO_PTEER (P05596), IOVO_PUCMA (P67956), IOVO_PYGAD (P67941), IOVO_RADRA (P68157), IOVO_RHEAM (P67942), IOVO_RHEPE (P67943), IOVO_RHYFU (P52251), IOVO_ROLRO (P52252), IOVO_SARME (P68156), IOVO_SCYNO (P52253), IOVO_SPHHU (P05563), IOVO_STRCA (P05557), IOVO_SYREL (P67958), IOVO_SYRHU (P67959), IOVO_SYRMI (P52269), IOVO_SYRRE (P05605), IOVO_SYRSO (P67960), IOVO_TINMA (P52254), IOVO_TRABL (P67946), IOVO_TRACA (P67947), IOVO_TRASA (P67948), IOVO_TRATE (P67949), IOVO_TURME (P52256), IOVO_TURSY (P05611), IOVO_TYMCU (P67944), IOVO_VANSP (P68384), IOVO_VULGR (P20846), IPSG_CANLF (P01002), IPSG_FELCA (P08480), IPSG_MARMT (P81482), IPSG_MELME (P16226), IPSG_MUSLU (P81481), IPSG_PANLE (P08481), IPSG_PANUN (P81262), IPSG_VULVU (P08479), ISK10_MOUSE (Q8CAC8), ISK11_MOUSE (Q09TK7), ISK12_MOUSE (Q9D256), ISK13_MOUSE (Q3UTS8), ISK13_RAT (D3ZVP0), ISK14_HUMAN (Q6IE38), ISK14_RAT (Q6IE46), ISK1L_CHICK (P85000), ISK1L_RAT (P09656), ISK1_ANGAN (P11706), ISK1_BOVIN (P00996), ISK1_CANLF (P04542), ISK1_HORSE (P81634), ISK1_HUMAN (P00995), ISK1_MONDO (P81635), ISK1_MOUSE (P09036), ISK1_PIG(P00998), ISK1_RAT(P09655), ISK1_SHEEP (P00997), ISK1_STRCA (Q9PSM2), ISK2_HUMAN (P20155), ISK2_MACFA (P34953), ISK2_MOUSE (Q8BMY7), ISK2_RAT(Q6IE49), ISK4_HUMAN (O60575), ISK4_MOUSE (O35679), ISK4_PIG(P37109), ISK5_HUMAN (Q9NQ38), ISK6_BOVIN (P01001), ISK6_HUMAN (Q6UWN8), ISK6_MOUSE (Q8BT20), ISK6_RAT(Q6IE47), ISK7_HUMAN (P58062), ISK7_MOUSE (Q6IE32), ISK7_RAT(Q6IE51), ISK9_HUMAN (Q5DT21), KTIL_BOTSC (C0HL51), LDTI_HIRME (P80424), RECK_CHICK (A0A1D5PUP4), RECK_DANRE (A0A0R4IKU3), RECK_HUMAN (O95980), RECK_MOUSE (Q9Z0J1), THBI_RHOPR (Q06684)» more
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UniProtKB/Swiss-Prot False negative sequences |
65 sequences
CALT_CAVPO (P22074), COW_DROME (Q9VCR3), EPI10_PHYIN (Q6PQG3), EPI10_PHYIT (D0NJ41), ESM1_DROME (O97176), ESM1_DROSI (B4QW11), FSTA_DANRE (Q9YHV4), FSTL1_HUMAN (Q12841), FSTL1_MOUSE (Q62356), FSTL1_PONAB (Q5R9Y1), FSTL1_RAT (Q62632), FSTL3_BOVIN (Q1LZB9), FSTL3_HUMAN (O95633), FSTL3_MOUSE (Q9EQC7), FSTL3_RAT (Q99PW7), FSTL4_HUMAN (Q6MZW2), FSTL4_MOUSE (Q5STE3), FSTL5_HUMAN (Q8N475), FSTL5_MOUSE (Q8BFR2), FST_BOVIN (P50291), FST_BUBBU (A5YT95), FST_CHICK (Q90844), FST_HORSE (O62650), FST_HUMAN (P19883), FST_MOUSE (P47931), FST_PIG (P10669), FST_RAT (P21674), FST_SHEEP (P31514), FST_XENLA (P31515), HTR1B_DANRE (A9JRB3), HTRA1_BOVIN (F1N152), HTRA1_RAT (Q9QZK5), HTRA1_XENLA (A6YFB5), HTRA1_XENTR (A4IHA1), HTRA3_HUMAN (P83110), HTRA3_MOUSE (Q9D236), HTRA3_RAT (D3ZA76), HTRA4_BOVIN (E1BJW1), HTRA4_HUMAN (P83105), IELA_ANESU (P16895), IGFBP_CUPSA (G4V4G1), IPK2_CENMR (P84755), MCPI_MELCP (P82968), PEG_DROME (Q9VDG1), SO74D_DROME (Q9VVH9), SPIKL_MOUSE (Q8CEK3), TU11_LOPAL (P0DKM9), TU91_GEMLI (P0DKT5), TU91_IOTCI (P0DKM8), TU91_IOTOL (P0DKM7), TU92_GEMSO (P0DKT2), TU92_IOTCI (P0DKT4), TU92_POLAB (P0DKT1), TU93_GEMSP (P0DKT3), VASO1_TABYA (C1IBZ2), VASO2_TABYA (C8YJB3), VASO3_TABYA (C8YJB4), VASOT_HYBBI (P84843), WFKN1_HUMAN (Q96NZ8), WFKN1_MOUSE (Q8R0S6), WFKN1_RAT (P0C5J5), WFKN2_BOVIN (Q08E66), WFKN2_HUMAN (Q8TEU8), WFKN2_MOUSE (Q7TQN3), WFKN_DANRE (Q6NUX0)» more |
UniProtKB/Swiss-Prot False positive sequences |
2 sequences
MADD_CAEEL (O02626), TUL1_YEAST (P36096) |
PDB [Detailed view] |
72 PDB
1AN1; 1BUS; 1CGI; 1CGJ; 1CHO; 1CSO; 1CT0; 1CT2; 1CT4; 1DS2; 1DS3; 1HJA; 1HPT; 1IY5; 1IY6; 1KMA; 1LDT; 1M8B; 1M8C; 1OMT; 1OMU; 1OVO; 1PCE; 1PPF; 1R0R; 1SGD; 1SGE; 1SGN; 1SGP; 1SGQ; 1SGR; 1SGY; 1TBQ; 1TBR; 1TGS; 1TUR; 1TUS; 1UVF; 1UVG; 1Y1C; 1YU6; 1Z7K; 2BUS; 2GKR; 2GKT; 2GKV; 2JXD; 2KMO; 2KMP; 2KMQ; 2KMR; 2LEO; 2N52; 2NU0; 2NU1; 2NU2; 2NU3; 2NU4; 2OVO; 2SGD; 2SGE; 2SGF; 2SGP; 2SGQ; 3OVO; 3SGB; 3SGQ; 4OVO; 6KBR; 7QE8; 7QE9; 8TZP » more |