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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00283


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PURL: https://purl.expasy.org/prosite/signature/PS00283

Direct ScanProsite submission
General information about the entry

Entry name [info] SOYBEAN_KUNITZ
Accession [info] PS00283
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00255

Name and characterization of the entry

Description [info] Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature.
Pattern [info]
[LIVM]-x-D-{EK}-[EDNTY]-[DG]-[RKHDENQ]-x-[LIVM]-x-{E}-{Q}-x(2)-Y-x-
[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 81 in 81 different sequences
Number of true positive hits 64 in 64 different sequences
Number of 'unknown' hits 0
Number of false positive hits 17 in 17 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 16
Precision (true positives / (true positives + false positives)) 79.01 %
Recall (true positives / (true positives + false negatives)) 86.49 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
64 sequences

ALB1_PSOTE  (P15465), API10_SOLTU (Q03197), API11_SOLTU (P16348), 
API1_SOLTU  (Q41480), API2_SOLTU  (Q43646), API4_SOLTU  (Q43645), 
API5_SOLTU  (P58519), API7_SOLTU  (Q41448), API8_SOLTU  (P17979), 
API9_SOLTU  (P58521), ASP_THECC   (P32765), CPI10_SOLTU (O24383), 
CPI1_SOLTU  (P20347), CPI2_SOLTU  (P24744), CPI7_SOLTU  (O24385), 
CPI8_SOLTU  (O24384), CPI9_SOLTU  (Q00652), GWIN3_POPSP (P16335), 
IAAS_HORVU  (P07596), IAAS_ORYSJ  (P29421), IAAS_WHEAT  (P16347), 
ICW3_PSOTE  (P10822), ID5A_ADEPA  (P09941), ID5A_NELJU  (P32733), 
IDE3_ERYCA  (P09943), IDE3_ERYCO  (P68170), IDE3_ERYLA  (P68171), 
IDE3_ERYVA  (P81366), IECI_ERYVA  (P34952), IELK1_BAURF (P84881), 
IFXA_BAUUN  (P83594), IT1A_PSOTE  (P10821), IT1B_ERYVA  (P81365), 
IT1B_PSOTE  (P32877), IT2_PSOTE   (P25700), ITRA_ALBJU  (P24925), 
ITRA_SOYBN  (P01070), ITRB_SOYBN  (P01071), ITRY_ACACO  (P24924), 
ITRY_ENTCO  (P86451), ITRY_LEULE  (P83036), KTI1_INGVE  (C0HKQ3), 
KTI1_SELCO  (C0HM47), KTI1_SELUD  (C0HM46), KTI1_SOYBN  (P25272), 
KTI2_SOYBN  (P25273), KTI4_ARATH  (Q8RXD5), KTI5_ARATH  (Q9LMU2), 
KTI6_ARATH  (Q0WNE5), KTI7_ARATH  (Q9M8Y9), LSPI_CARPA  (P80691), 
MIRA_SYNDU  (P13087), PIP21_PEA   (Q41015), PIP22_PEA   (O82711), 
RRP5_ARATH  (F4J8K6), SPI1_SOLTU  (P58514), SPI2_SOLTU  (P58515), 
SPI5_SOLTU  (Q41484), SPI6_SOLTU  (Q41433), SPI8_SOLTU  (P24743), 
SPOR1_IPOBA (P14715), SPOR2_IPOBA (P14716), SPORA_IPOBA (P10917), 
SPORB_IPOBA (P10965)
» more

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

BBCI_BAUBA  (P83051), BBKI_BAUBA  (P83052), DRTI_DELRE  (P83667), 
ICI2_CANLI  (P81726), IPRA_SAGSA  (P31608), IPRB_SAGSA  (P07479), 
ITC_ALOMA   (P35812), ITRY1_BAURF (P84882), ITRY_BAUVA  (P83595), 
SPI7_SOLTU  (P30941)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
16 sequences

AFPJ_SOLTU  (P84794), AFP_CULCO   (P85102), API3_SOLTU  (P58518), 
API6_SOLTU  (P58520), CEKI_PAUEC  (P84795), CPI3_SOLTU  (O24388), 
CPI4_SOLTU  (P58602), CPI5_SOLTU  (O24387), CPI6_SOLTU  (O24386), 
ISOTI_SPIOL (P86549), ITRA_ALBKA  (P85498), ITRY_ARCEL  (P84890), 
ITRY_CASLE  (C0HK48), SPI3_SOLTU  (P58516), SPI4_SOLTU  (P58517), 
TURM_CURLO  (P85278)
» more

UniProtKB/Swiss-Prot
False positive sequences
17 sequences

COLB_DICDI  (Q8T2A1), CY550_PARMW (Q7U8S5), CY550_SYNS3 (Q0I7X4), 
CY550_SYNS9 (Q3AZH8), CY550_SYNSC (Q3AHP7), DFFB_BOVIN  (Q58CZ0), 
MPH1_PICST  (A3GH78), NIR_CERS5   (Q53239), PRX7_PENRW  (B6H061), 
RBS1_PETHY  (P04714), RBS2_PETHY  (P04715), RBS2_SOLTU  (P26574), 
RPOB_MOOTA  (Q2RFN9), SL9C1_MOUSE (Q6UJY2), THADA_CANLF (A8C750), 
TRY5_CANAL  (Q5A4K7), UAP1L_XENTR (Q28CH3)
» more

PDB
[Detailed view]
37 PDB

pdb_00001ava; pdb_00001avu; pdb_00001avw; pdb_00001avx; pdb_00001ba7; pdb_00001eyl; pdb_00001fmz; pdb_00001fn0; pdb_00001tie; pdb_00001wba; pdb_00001wbc; pdb_00001xg6; pdb_00002bea; pdb_00002beb; pdb_00002esu; pdb_00002et2; pdb_00002iwt; pdb_00002qn4; pdb_00002qyi; pdb_00002wbc; pdb_00003bx1; pdb_00003i29; pdb_00003i2a; pdb_00003i2x; pdb_00003qyd; pdb_00003s8j; pdb_00003s8k; pdb_00003veq; pdb_00004h9w; pdb_00004ha2; pdb_00004j2k; pdb_00004j2y; pdb_00004tlp; pdb_00004wbc; pdb_00005dzu; pdb_00006ntt; pdb_00006o1f
» more