PROSITE entry PS00284
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PURL: https://purl.expasy.org/prosite/signature/PS00284
Direct ScanProsite submission
General information about the entry
| Entry name [info] | SERPIN |
| Accession [info] | PS00284 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00256 |
Name and characterization of the entry
| Description [info] | Serpins signature. |
| Pattern [info] |
[LIVMFY]-{G}-[LIVMFYAC]-[DNQ]-[RKHQS]-[PST]-F-[LIVMFY]-[LIVMFYC]-x-
[LIVMFAH].
|
Numerical results [info]
| Total number of hits | 368 in 368 different sequences |
| Number of true positive hits | 251 in 251 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 117 in 117 different sequences |
| Number of false negative sequences | 40 |
| Number of 'partial' sequences | 12 |
| Precision (true positives / (true positives + false positives)) | 68.21 % |
| Recall (true positives / (true positives + false negatives)) | 86.25 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
251 sequences
A1AF_CAVPO (P22324), A1AF_RABIT (P23035), A1AS_CAVPO (P22325), A1AT1_HORSE (P38028), A1AT1_MOUSE (P07758), A1AT2_HORSE (P38029), A1AT2_MOUSE (P22599), A1AT3_MOUSE (Q00896), A1AT4_HORSE (P38031), A1AT4_MOUSE (Q00897), A1AT5_MOUSE (Q00898), A1AT6_MOUSE (Q9DCQ7), A1ATR_HUMAN (P20848), A1AT_BOMMO (P22922), A1AT_BOVIN (P34955), A1AT_CALCN (O54763), A1AT_CHLAE (O00394), A1AT_CYPCA (P32759), A1AT_HUMAN (P01009), A1AT_MUSCR (P26595), A1AT_MUSSA (Q63969), A1AT_NOTEU (P38027), A1AT_PAPAN (P01010), A1AT_PIG(P50447), A1AT_PONAB (Q5RCW5), A1AT_RAT(P17475), A1AT_SHEEP (P12725), A2AP_BOVIN (P28800), A2AP_HUMAN (P08697), A2AP_MOUSE (Q61247), A76A_DROME (Q9VVW1), AACT_HUMAN (P01011), AACT_PONAB (Q5R536), ACH1_BOMMO (Q03383), ACH2_BOMMO (P80034), ALLT_ICTTR (O54762), ALMM_TAMSI (O54757), ALMS_ICTTR (O54761), ALMS_TAMSI (O54758), ALSI_TAMSI (O54760), ALST_TAMSI (O54759), ANGT_BOVIN (P01017), ANGT_CALJA (Q9TSZ0), ANGT_GORGO (Q9GLP6), ANGT_HUMAN (P01019), ANGT_PANTR (Q9GLN8), ANGT_SHEEP (P20757), ANT3_HUMAN (P01008), ANT3_MOUSE (P32261), ANT3_PONAB (Q5R5A3), ANT3_SHEEP (P32262), BSZ7_HORVU (Q43492), CBG_BOVIN (E1BF81), CBG_HUMAN (P08185), CBG_MESAU (Q60543), CBG_MOUSE (Q06770), CBG_PIG (Q9GK37), CBG_PONAB (Q5R9E3), CBG_RABIT (P23775), CBG_RAT (P31211), CBG_SAISC (P50451), CBG_SHEEP (P49920), CBG_URSAR (B2D1U1), EP45_XENLA (Q00387), F12AI_BOVIN (P50448), GDN_HUMAN (P07093), GDN_MOUSE (Q07235), GDN_RAT (P07092), HEP2_HUMAN (P05546), HEP2_MOUSE (P49182), HEP2_RABIT (P47776), HEP2_RAT(Q64268), HP55_TAMSI (Q09055), IC1_HUMAN (P05155), IC1_MOUSE (P97290), IC1_RABIT (Q9TRG2), IC1_RAT (Q6P734), ILEUA_MOUSE (Q9D154), ILEUA_RAT (Q4G075), ILEUB_MOUSE (Q8VHP7), ILEUC_MOUSE (Q5SV42), ILEU_BOVIN (Q1JPB0), ILEU_HORSE (P05619), ILEU_HUMAN (P30740), ILEU_PIG(P80229), ILEU_XENLA (Q52L45), ILEU_XENTR (Q5I0S8), IPIS1_IXOPE (A0A090BX51), IPSP_BOVIN (Q9N2I2), IPSP_HUMAN (P05154), IRIS_IXORI (Q9GP13), IRS1_IXORI (Q06B75), IRS2_IXORI (Q06B74), IRS3_IXORI (A0A0K8RCY5), IRS4_IXORI (A0A0K8RJV9), IRS5_IXORI (A0A0K8RJ89), IRS8_IXORI (Q06B72), KAIN_HUMAN (P29622), KAIN_PONAB (Q5RCR2), LICI1_TACTR (Q27085), LICI2_TACTR (Q27086), LICI3_TACTR (Q94823), NEUS_CHICK (Q90935), NEUS_HUMAN (Q99574), NEUS_MOUSE (O35684), NEUS_RAT(Q9JLD2), OVALX_CHICK (P01013), OVALY_CHICK (P01014), OVAL_CHICK (P01012), OVAL_COTCO (Q6V115), OVAL_COTJA (P19104), OVAL_DRONO (E2RVI8), OVAL_MELGA (O73860), PAI1_BOVIN (P13909), PAI1_HUMAN (P05121), PAI1_MOUSE (P22777), PAI1_NEOVI (P50449), PAI1_PIG(P79335), PAI1_RAT(P20961), PAI2_HUMAN (P05120), PAI2_MOUSE (P12388), PAI2_RAT(P29524), PEDF_BOVIN (Q95121), PEDF_HUMAN (P36955), PEDF_MOUSE (P97298), SERA_MANSE (P14754), SERP3_BOVIN (A6QQ92), SERP3_DANRE (B0UYL8), SERP3_HUMAN (A8MV23), SERPH_BOVIN (Q2KJH6), SERPH_CHICK (P13731), SERPH_HUMAN (P50454), SERPH_MOUSE (P19324), SERPH_PONAB (Q5RBS3), SERPH_RAT (P29457), SP27A_DROME (Q9V3N1), SP2_ANOGA (Q7QIJ8), SP88E_DROME (Q9VFC2), SPA12_MOUSE (Q7TMF5), SPA31_BOVIN (Q9TTE1), SPA32_BOVIN (A2I7M9), SPA33_BOVIN (Q3ZEJ6), SPA34_BOVIN (A2I7N0), SPA35_BOVIN (A2I7N1), SPA36_BOVIN (A2I7N2), SPA37_BOVIN (A2I7N3), SPA38_BOVIN (A6QPQ2), SPA3C_MOUSE (P29621), SPA3F_MOUSE (Q80X76), SPA3G_MOUSE (Q5I2A0), SPA3K_CAVPO (P22323), SPA3K_MOUSE (P07759), SPA3K_RAT (P05545), SPA3L_RAT (P05544), SPA3M_MOUSE (Q03734), SPA3M_RAT (Q63556), SPA3N_MOUSE (Q91WP6), SPA3N_RAT (P09006), SPA9_HUMAN (Q86WD7), SPB10_BOVIN (A5PJK0), SPB10_CALJA (B0CMB0), SPB10_HUMAN (P48595), SPB10_MOUSE (Q8K1K6), SPB10_OTOGA (B4USX2), SPB10_PAPAN (A9RA96), SPB10_PLEMO (B1MTC3), SPB10_RAT (Q8K3K4), SPB10_RHIFE (B2KI30), SPB10_SORAR (B3RFC3), SPB11_HUMAN (Q96P15), SPB12_HUMAN (Q96P63), SPB12_MOUSE (Q9D7P9), SPB13_HUMAN (Q9UIV8), SPB13_MOUSE (Q8CDC0), SPB3_HUMAN (P29508), SPB4_HUMAN (P48594), SPB5_HUMAN (P36952), SPB5_MOUSE (P70124), SPB5_PLEMO (B1MTB7), SPB5_RAT(P70564), SPB5_XENLA (Q6GLQ1), SPB5_XENTR (Q5M8J5), SPB6_BOVIN (O02739), SPB6_HUMAN (P35237), SPB6_MACFA (Q4R3G2), SPB6_MOUSE (Q60854), SPB6_PONAB (Q5R899), SPB7_HUMAN (O75635), SPB7_MOUSE (Q9D695), SPB8_BOVIN (Q5BIR5), SPB8_HUMAN (P50452), SPB8_MOUSE (O08800), SPB9_HUMAN (P50453), SPI1_CWPXB (P42927), SPI1_MONPV (A0A7H0DNG4), SPI1_MYXVL (P12393), SPI1_RABPU (P42928), SPI1_VACCC (P20531), SPI1_VACCW (P15058), SPI1_VAR67 (P0DOT3), SPI1_VARV (P0DOT4), SPI21_RAT (P09005), SPI24_APOSY (Q60396), SPI2B_VACCC (P20842), SPI2_CWPXB (P07385), SPI2_HUMAN (O75830), SPI2_MONPV (A0A7H0DNF9), SPI2_MOUSE (Q9JK88), SPI2_MYXVL (P68565), SPI2_MYXVU (P68566), SPI2_RABPU (P42926), SPI2_VACCW (P15059), SPI2_VAR67 (P0DSW3), SPI2_VARV (P0DSW4), SPI_CYACP (Q6J201), SPZ10_ARATH (Q9SIR9), SPZ12_ORYSJ (Q5NBM0), SPZ1A_WHEAT (Q41593), SPZ1B_WHEAT (P93693), SPZ1C_WHEAT (Q9ST58), SPZ1_ARATH (Q9SH52), SPZ1_ORYSJ (Q94DW6), SPZ2A_WHEAT (Q9ST57), SPZ2B_WHEAT (P93692), SPZ2_ARATH (Q9ZQR6), SPZ3_ARATH (O48706), SPZ4_ARATH (Q9M1T7), SPZ4_HORVU (P06293), SPZ5_ARATH (O04582), SPZ9_ORYSJ (Q2R8P2), SPZXA_ORYSJ (Q75H81), SPZXB_ORYSJ (Q10GX0), SPZX_ARATH (Q9S7T8), SPZX_HORVU (Q40066), THBG_BOVIN (Q9TT36), THBG_HUMAN (P05543), THBG_PANTR (P61640), THBG_PIG(Q9TT35), THBG_RAT(P35577), THBG_SHEEP (P50450), UFAP2_PIG (P46202), UFAP_PIG(P16708), UTMP_BOVIN (P46201), UTMP_SHEEP (P21814), V044_FOWPN (Q9J5F9), V204_FOWPN (Q9J531), Y049_PYRAE (Q8ZZW3), Y1782_THEKO (Q5JJ64), Y2246_METAC (Q8TNN7), Y2678_METMA (Q8PTN8), Y3388_METAC (Q8TKL5)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
40 sequences
A1AT_DIDVI (Q03044), A1AT_MERUN (Q64118), A1AT_MESAU (P97277), ANGT_MOUSE (P11859), ANGT_RAT(P01015), ANT3_BOVIN (P41361), HMSD_HUMAN (A8MTL9), IPSP_MOUSE (P70458), PG040_VACCA (Q85339), PG040_VACCC (P20532), PG040_VACCW (P18384), PG040_VAR67 (P33831), SP28D_DROME (Q9VLU4), SP42D_DROME (Q7YTY6), SPA11_HUMAN (Q86U17), SPA11_MOUSE (Q8CIE0), SPA12_HUMAN (Q8IW75), SPA12_RAT (Q8R4Z1), SPA9_MOUSE (Q9D7D2), SPB10_CHICK (O73790), SPB11_MOUSE (Q9CQV3), SPI1_SWPVK (Q08519), SPI3_LONON (Q5MGH0), SPZ10_ORYSJ (Q7XMK1), SPZ11_ORYSJ (Q7XMK0), SPZ2A_ORYSJ (Q53KS8), SPZ2B_ORYSJ (Q53KS9), SPZ5_ORYSJ (Q53MD3), SPZ6A_ORYSJ (Q53Q31), SPZ6B_ORYSJ (Q53Q32), SPZ6C_ORYSJ (Q53MD1), SPZ8_ORYSJ (Q53P09), THBG_MOUSE (P61939), V010_FOWPN (Q9J5J1), V040_FOWPN (Q9J5G3), V251_FOWPN (P14369), Y2613_METAC (Q8TMP0), YR700_MIMIV (Q7T6X8), ZPI_HUMAN (Q9UK55), ZPI_RAT (Q62975)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
12 sequences
A1AT3_HORSE (P38030), A1AT_CHILA (P38026), A2AP_STRCA (P83168), ANGT1_BOTJA (Q10581), ANGT2_BOTJA (Q10582), ANGT_CHICK (P67885), ANGT_COTJA (P67886), ANGT_HORSE (P01016), ANGT_THETS (Q10757), ANT3_CHICK (Q03352), ANT3_MESAU (P81050), SPI_HALRO (Q10997)» more |
| UniProtKB/Swiss-Prot False positive sequences |
117 sequences
ARLY_BUCAI (P57159), AROB_BUCAI (P57604), BALAT_DROME (Q961J5), CADH2_DANRE (Q90275), CFT1_CANAL (Q5AFT3), CH60_CUPMC (Q1LQS4), CH60_CUPPJ (Q46XW6), CH60_MANSM (Q65VE4), CH60_PLUGE (O66194), CH60_PSEA6 (Q15PD3), CH60_SHEB5 (A3D8W9), CH60_SHEB8 (A6WJ17), CH60_SHEDO (Q12S61), CH60_SHEFN (Q07WX7), CH60_SHEON (Q8CX48), CH60_SHEPC (A4Y398), CH60_SHESA (A0L170), CH60_SHESM (Q0HEQ4), CH60_SHESR (Q0HZ97), CH60_SHESW (A1RNN6), CHA4_YEAST (P43634), CIDEC_HUMAN (Q96AQ7), CTR3_YEAST (Q06686), DCL4_ORYSJ (A7LFZ6), DISP1_MOUSE (Q3TDN0), DLG2_HUMAN (Q15700), EFTU_LEPBY (P50066), EIK1_PLAF7 (Q8IL26), ELCC_PHANO (Q0UI03), ENGB_EHRCJ (Q3YS22), ERA_AGRFC (Q8UGK1), ERA_BRUME (Q8YG75), ERA_BRUSU (Q8G1P9), FER7_MYCMD (A1A654), FPG_PARUW (Q6MCT3), HIR3_YEAST (P47171), HTS1_COCCA (Q01886), ICAC_STAA8 (Q9RQP6), ICAC_STAAM (Q931E4), ICAC_STAAN (Q7A348), ICAC_STAAR (Q6GDD5), ICAC_STAAS (Q6G605), ICAC_STAAW (Q79ZV2), IP5P3_ARATH (Q8H0Z6), KS6A3_HUMAN (P51812), KS6A3_MOUSE (P18654), KS6A6_DANRE (Q6PFQ0), KS6A6_HUMAN (Q9UK32), KS6A6_MOUSE (Q7TPS0), LSPA_WOLSU (Q7M9M1), MEK1_CAEEL (Q21307), MLCE_PENCI (Q8J0F3), MSH3_BOTFB (A6RPB6), MSH3_SCLS1 (A7EC69), MURC_WOLTR (Q5GTG5), NBDA_PSEAE (Q9HYT3), NHAA1_CAMJ8 (A8FNW6), NHAA1_CAMJD (A7H5Z9), NHAA1_CAMJE (Q0P7X4), NHAA1_CAMJJ (A1W1Q6), NHAA1_CAMJR (Q5HSD9), NLRP9_BOVIN (Q288C4), NU2M_PARTE (P15577), NU4M_MYXGL (Q9G2W9), NU6M_CHLRE (P10329), PFL3_SCHPO (Q874R4), PHNW_LYSSC (B1HPR6), PLXC1_HUMAN (O60486), PLXC1_MOUSE (Q9QZC2), POMT2_DANRE (F1Q8R9), POMT2_HUMAN (Q9UKY4), POMT2_MOUSE (Q8BGQ4), RELE4_METJA (Q58573), RLMKL_IDILO (Q5QX63), RLMKL_PSEA6 (Q15UB5), RNFE_VIBPA (Q87MW9), RNFE_VIBVU (Q8D885), RNFE_VIBVY (Q7MM86), S35F3_MOUSE (Q1LZI2), SID1_CAEEL (Q9GZC8), SPNS3_MOUSE (Q9D232), SRB8_PICST (A3GF47), STSY_RAUMA (P68174), STSY_RAUSE (P68175), SYA_BACAH (A0RJ00), SYA_BACAN (Q81LK0), SYA_BACC1 (P61697), SYA_BACCN (A7GT67), SYA_BACCR (Q817Z0), SYA_BACCZ (Q634F6), SYA_BACHK (Q6HDD7), SYA_BACLD (Q65GS5), SYA_BACMK (A9VI09), SYE1_CAMC5 (A7GXI1), SYI_ANTLO (Q27707), T214A_MARPO (P12221), TERT_ARATH (Q9SPU7), TOLB_CAMJE (Q9PJ14), TOLB_CAMJR (Q5HX54), TOLB_HELPH (Q1CSE0), TOLB_HELPJ (Q9ZK86), TOLB_HELPY (O25751), TPN50_TREPA (P38369), UL79_SHV21 (Q01003), UNC5D_HUMAN (Q6UXZ4), UNC5D_MOUSE (Q8K1S2), UNC5D_RAT (F1LW30), UVRC_WOLTR (Q5GSR4), VL3_HPV5B (P26541), VPR_LACPL (F9USN6), Y3085_AZOC5 (Q04855), Y3264_ARATH (P0C897), YHJN_BACSU (O07568), YIDC_STRAW (P59811), YIDC_STRCO (O54569), YQOA_CAEEL (Q09299), ZDHC5_DICDI (Q554E7)» more |
| PDB [Detailed view] |
187 PDB
pdb_00001a7c; pdb_00001ant; pdb_00001as4; pdb_00001ath; pdb_00001att; pdb_00001atu; pdb_00001azx; pdb_00001b3k; pdb_00001br8; pdb_00001by7; pdb_00001c5g; pdb_00001c8o; pdb_00001d5s; pdb_00001db2; pdb_00001dvm; pdb_00001dvn; pdb_00001dzg; pdb_00001dzh; pdb_00001e03; pdb_00001e04; pdb_00001e05; pdb_00001ezx; pdb_00001f0c; pdb_00001hle; pdb_00001hp7; pdb_00001imv; pdb_00001jjo; pdb_00001jmj; pdb_00001jmo; pdb_00001jrr; pdb_00001jti; pdb_00001jvq; pdb_00001k9o; pdb_00001kct; pdb_00001lj5; pdb_00001lk6; pdb_00001lq8; pdb_00001m93; pdb_00001nq9; pdb_00001oc0; pdb_00001oo8; pdb_00001oph; pdb_00001ova; pdb_00001oyh; pdb_00001psi; pdb_00001qlp; pdb_00001qmn; pdb_00001r1l; pdb_00001sek; pdb_00001sr5; pdb_00001t1f; pdb_00001tb6; pdb_00001uhg; pdb_00001wz9; pdb_00001xqg; pdb_00001xqj; pdb_00001xu8; pdb_00001yxa; pdb_00002ach; pdb_00002ant; pdb_00002arq; pdb_00002arr; pdb_00002b4x; pdb_00002b5t; pdb_00002beh; pdb_00002ceo; pdb_00002d26; pdb_00002gd4; pdb_00002hi9; pdb_00002hij; pdb_00002oay; pdb_00002ol2; pdb_00002qug; pdb_00002r9y; pdb_00002riv; pdb_00002riw; pdb_00002v95; pdb_00002vdx; pdb_00002vdy; pdb_00002wxw; pdb_00002x0b; pdb_00002xn3; pdb_00002xn5; pdb_00002xn6; pdb_00002xn7; pdb_00002znh; pdb_00002zv6; pdb_00003b9f; pdb_00003caa; pdb_00003cvm; pdb_00003cwl; pdb_00003cwm; pdb_00003drm; pdb_00003dru; pdb_00003dy0; pdb_00003eox; pdb_00003evj; pdb_00003f02; pdb_00003f5n; pdb_00003fgq; pdb_00003kcg; pdb_00003le2; pdb_00003lw2; pdb_00003nda; pdb_00003ndd; pdb_00003ndf; pdb_00003ne4; pdb_00003pb1; pdb_00003pzf; pdb_00003q02; pdb_00003q03; pdb_00003r4l; pdb_00003t1p; pdb_00003ut3; pdb_00004aqh; pdb_00004bb2; pdb_00004c41; pdb_00004c49; pdb_00004caa; pdb_00004dy0; pdb_00004dy7; pdb_00004eb1; pdb_00004g8o; pdb_00004g8r; pdb_00004ga7; pdb_00004ic0; pdb_00004pyw; pdb_00004ro9; pdb_00004roa; pdb_00004rob; pdb_00004rsq; pdb_00004x30; pdb_00004yia; pdb_00004zk0; pdb_00004zk3; pdb_00005brr; pdb_00005du3; pdb_00005duq; pdb_00005io1; pdb_00005m3x; pdb_00005m3y; pdb_00005nbu; pdb_00005nbv; pdb_00005zlz; pdb_00006bj5; pdb_00006f02; pdb_00006gwn; pdb_00006gwp; pdb_00006gwq; pdb_00006hge; pdb_00006hx4; pdb_00006i3f; pdb_00006i3i; pdb_00006i4v; pdb_00006i7u; pdb_00006i8s; pdb_00006iay; pdb_00006kga; pdb_00006los; pdb_00006rod; pdb_00006zrv; pdb_00007ael; pdb_00007ahp; pdb_00007akv; pdb_00007api; pdb_00007aqf; pdb_00007aqg; pdb_00007b2t; pdb_00007npk; pdb_00007npl; pdb_00007pmu; pdb_00007qtz; pdb_00007zas; pdb_00007zbf; pdb_00008api; pdb_00008p4j; pdb_00008p4u; pdb_00008pi2; pdb_00008qz5; pdb_00008r13; pdb_00008r21; pdb_00008w18; pdb_00008zcr; pdb_00009api; pdb_00009c2t; pdb_00009d7k; pdb_00009pai » more |