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Entry: PS00288

General information about the entry

Entry name [info] TIMP
Accession [info] PS00288
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-JUL-1999 DATA UPDATE;
16-OCT-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC00260

Name and characterization of the entry

Description [info] Tissue inhibitors of metalloproteinases signature.
Pattern [info] 
C-x-C-x-P-x-H-P-Q-x(2)-[FIV]-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_09 which contains 561'176 sequence entries.


Total number of hits 33 in 33 different sequences
Number of true positive hits 33 in 33 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 89.19 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 33 sequences 

TIMP1_BOVIN (P20414    ), TIMP1_HORSE (O02722    ), TIMP1_HUMAN (P01033    ), 

TIMP1_MOUSE (P12032    ), TIMP1_PAPCY (P49061    ), TIMP1_PIG   (P35624    ), 
TIMP1_PONAB (Q5RC60    ), TIMP1_RABIT (P20614    ), TIMP1_RAT   (P30120    ), 
TIMP1_SHEEP (P50122    ), TIMP2_BOVIN (P16368    ), TIMP2_CANLF (Q9TTY1    ), 
TIMP2_CAVPO (Q9WUC6    ), TIMP2_CHICK (O42146    ), TIMP2_CRILO (Q60453    ), 
TIMP2_HUMAN (P16035    ), TIMP2_MOUSE (P25785    ), TIMP2_RABIT (Q9TRZ7    ), 
TIMP2_RAT   (P30121    ), TIMP3_BOVIN (P79121    ), TIMP3_CHICK (P26652    ), 
TIMP3_HORSE (Q9TUL9    ), TIMP3_HUMAN (P35625    ), TIMP3_MACFA (P61269    ), 
TIMP3_MACMU (Q5PXZ9    ), TIMP3_MOUSE (P39876    ), TIMP3_RAT   (P48032    ), 
TIMP3_SCYTO (Q9W6B4    ), TIMP3_XENLA (O73746    ), TIMP4_BOVIN (O97563    ), 
TIMP4_HUMAN (Q99727    ), TIMP4_MOUSE (Q9JHB3    ), TIMP4_RAT   (P81556    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

TIMP1_CANLF (P81546    ), TIMP1_MACMU (Q95KL9    ), TIMPL_CAEEL (Q21265    ), 

TIMP_DROME  (Q9VH14    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

TIMP3_RABIT (O97590    ), TIMP4_RABIT (O97591    )


				
	

	

		PDB
[Detailed view]		
		
			16 PDB
			


			1BQQ; 1BR9; 1BUV; 1D2B; 1GXD; 1OO9; 1UEA; 2E2D; 2J0T; 2TMP; 3CKI; 3MA2; 
			
				3V96; 4ILW; 6MAV; 6N9D
			
			

			» more

				
	





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