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PROSITE entry PS00289


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00289
Entry name [info] PTX_1
Accession [info] PS00289
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00261

Name and characterization of the entry

Description [info] Pentraxin domain signature.
Pattern [info] 
H-x-C-x-[ST]-W-x-[ST].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 34 in 34 different sequences
Number of true positive hits 32 in 32 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 21
Number of 'partial' sequences 10
Precision (true positives / (true positives + false positives)) 94.12 %
Recall (true positives / (true positives + false negatives)) 60.38 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 32 sequences 

CRP1_LIMPO  (P06205), CRP3_LIMPO  (P06207), CRP4_LIMPO  (P06206), 

CRP_CAVPO   (P49254), CRP_HUMAN   (P02741), CRP_MESAU   (P49262), 
CRP_MOUSE   (P14847), CRP_PIG (O19062), CRP_RABIT   (P02742), 
CRP_RAT (P48199), CRP_XENLA   (Q07203), FP_NOTMI(P15697), 
MPTX_BOVIN  (Q3T166), NPTX1_HUMAN (Q15818), NPTX1_MOUSE (Q62443), 
NPTX1_RAT   (P47971), NPTX2_CAVPO (P47970), NPTX2_HUMAN (P47972), 
NPTX2_MOUSE (O70340), NPTX2_RAT   (P97738), NPTXR_MOUSE (Q99J85), 
PTX3_BOVIN  (Q0VCG9), PTX3_HUMAN  (P26022), PTX3_MOUSE  (P48759), 
PXN1_XENLA  (P49263), SAMP_BOVIN  (Q3T004), SAMP_CAVPO  (P49255), 
SAMP_HUMAN  (P02743), SAMP_MESAU  (P07629), SAMP_MOUSE  (P12246), 
SAMP_PIG(O19063), SAMP_RAT(P23680)
» more

UniProtKB/Swiss-Prot
False negative sequences		 21 sequences 

AGRD1_BOVIN (A6QLU6), AGRD1_HUMAN (Q6QNK2), AGRD1_MOUSE (Q80T32), 

AGRD2_HUMAN (Q7Z7M1), AGRG4_HUMAN (Q8IZF6), AGRG4_MOUSE (B7ZCC9), 
AGRG6_DANRE (C6KFA3), AGRG6_HUMAN (Q86SQ4), AGRG6_MOUSE (Q6F3F9), 
CRP_DANRE   (Q0IIP8), JELT_LEPLA  (Q9PTT2), MPTX_HUMAN  (A8MV57), 
MPTX_MOUSE  (Q8R1M8), MPTX_RAT(Q6TA48), NPTXR_HUMAN (O95502), 
NPTXR_RAT   (O35764), PTX4_HUMAN  (Q96A99), PTX4_MOUSE  (Q6RUU0), 
SVEP1_HUMAN (Q4LDE5), SVEP1_MOUSE (A2AVA0), SVEP1_RAT   (P0C6B8)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 10 sequences 

CRP1_GADMO  (P86688), CRP2_GADMO  (P86689), CRP_MUSCA   (P19094), 

CRP_PLEPL   (P12245), LIMU_LIMPO  (P02744), SAMP_ANALU  (P86694), 
SAMP_HIPHI  (P86695), SAMP_MUSCA  (P19095), SAMP_PLEPL  (P20677), 
SAMP_SALSA  (P86693)
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

CCNJL_HUMAN (Q8IV13), CRK23_ARATH (O65482)


				
	

	

		PDB
[Detailed view]		
		
			32 PDB
			


			1B09; 1GNH; 1GYK; 1LGN; 1LJ7; 1SAC; 2A3W; 2A3X; 2A3Y; 2W08; 3D5O; 3KQR; 
			
				3L2Y; 3PVN; 3PVO; 4AVS; 4AVT; 4AVV; 4AYU; 6YPE; 7PK9; 7PKB; 7PKD; 7PKE; 
				7PKF; 7PKG; 7PKH; 7TBA; 7ZL1; 8PVQ; 8WV4; 8WV5
			
			

			» more