PROSITE entry PS00311

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General information about the entry

Entry name [info]	LAMP_2
Accession [info]	PS00311
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-JUN-1994 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00280

Name and characterization of the entry

Description [info]	LAMP glycoproteins transmembrane and cytoplasmic domain signature.
Pattern [info]	C-x(2)-D-x(3,4)-[LIVM](2)-P-[LIVM]-x-[LIVM]-G-x(2)-[LIVM]-x-G-[LIVM](2)- x-[LIVM](4)-A-[FY]-x-[LIVM]-x(2)-[KR]-[RH]-x(1,2)-[STAG](2)-Y-[EQ].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.

Total number of hits	12 in 12 different sequences
Number of true positive hits	12 in 12 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	1
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	92.31 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

12 sequences

CD68_HUMAN  (P34810), CD68_MOUSE  (P31996), LAMP1_BOVIN (Q05204),

LAMP1_CHICK (P05300), LAMP1_CRIGR (P49129), LAMP1_HUMAN (P11279), 
LAMP1_MOUSE (P11438), LAMP1_RAT   (P14562), LAMP2_CRIGR (P49130), 
LAMP2_HUMAN (P13473), LAMP2_MOUSE (P17047), LAMP2_RAT   (P17046)

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UniProtKB/Swiss-Prot
False negative sequences

1 sequence

LAMP2_CHICK (Q90617)

PDB
[Detailed view]

2 PDB

8FY5; 8FYF