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PROSITE entry PS00311


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00311
Entry name [info] LAMP_2
Accession [info] PS00311
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-JUN-1994 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00280

Name and characterization of the entry

Description [info] LAMP glycoproteins transmembrane and cytoplasmic domain signature.
Pattern [info] 
C-x(2)-D-x(3,4)-[LIVM](2)-P-[LIVM]-x-[LIVM]-G-x(2)-[LIVM]-x-G-[LIVM](2)-
x-[LIVM](4)-A-[FY]-x-[LIVM]-x(2)-[KR]-[RH]-x(1,2)-[STAG](2)-Y-[EQ].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 12 in 12 different sequences
Number of true positive hits 12 in 12 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 92.31 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 12 sequences 

CD68_HUMAN  (P34810), CD68_MOUSE  (P31996), LAMP1_BOVIN (Q05204), 

LAMP1_CHICK (P05300), LAMP1_CRIGR (P49129), LAMP1_HUMAN (P11279), 
LAMP1_MOUSE (P11438), LAMP1_RAT   (P14562), LAMP2_CRIGR (P49130), 
LAMP2_HUMAN (P13473), LAMP2_MOUSE (P17047), LAMP2_RAT   (P17046)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

LAMP2_CHICK (Q90617)


				
	

	

		PDB
[Detailed view]		
		
			2 PDB
			


			8FY5; 8FYF