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PROSITE entry PS00311


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PURL: https://purl.expasy.org/prosite/signature/PS00311

Direct ScanProsite submission
General information about the entry

Entry name [info] LAMP_2
Accession [info] PS00311
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-JUN-1994 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00280

Name and characterization of the entry

Description [info] LAMP glycoproteins transmembrane and cytoplasmic domain signature.
Pattern [info]
C-x(2)-D-x(3,4)-[LIVM](2)-P-[LIVM]-x-[LIVM]-G-x(2)-[LIVM]-x-G-[LIVM](2)-
x-[LIVM](4)-A-[FY]-x-[LIVM]-x(2)-[KR]-[RH]-x(1,2)-[STAG](2)-Y-[EQ].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 12 in 12 different sequences
Number of true positive hits 12 in 12 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 92.31 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
12 sequences

CD68_HUMAN  (P34810), CD68_MOUSE  (P31996), LAMP1_BOVIN (Q05204), 
ยป more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

LAMP2_CHICK (Q90617)

		
PDB
[Detailed view]
2 PDB

8FY5; 8FYF