Due to maintenance work, this service will be unavailable from
Mon Nov 11 17:30 until
Tue Nov 12 09:00
CET.
Apologies for the inconvenience.
PROSITE entry PS00318
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| Entry name [info] | HMG_COA_REDUCTASE_2 |
| Accession [info] | PS00318 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00064 |
Name and characterization of the entry
| Description [info] | Hydroxymethylglutaryl-coenzyme A reductases signature 2. |
| Pattern [info] |
[LIVM]-G-x-[LIVM]-G-G-[AG]-T. |
Numerical results [info]
| Total number of hits | 93 in 93 different sequences |
| Number of true positive hits | 67 in 67 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 26 in 26 different sequences |
| Number of false negative sequences | 2 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 72.04 % |
| Recall (true positives / (true positives + false negatives)) | 97.10 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
67 sequences
HMDH1_ARATH (P14891), HMDH1_ASPFU (Q4WHZ1), HMDH1_DICDI (P34135), HMDH1_GIBZE (I1RXX1), HMDH1_GOSHI (O64966), HMDH1_HEVBR (P29057), HMDH1_ORYSI (A2X8W3), HMDH1_ORYSJ (Q0DY59), HMDH1_SOLTU (P48020), HMDH1_YEAST (P12683), HMDH2_ARATH (P43256), HMDH2_ASPFU (Q4WSY2), HMDH2_CAPAN (Q9XEL8), HMDH2_DICDI (P34136), HMDH2_GOSHI (O64967), HMDH2_HEVBR (P29058), HMDH2_SOLLC (P48022), HMDH2_SOLTU (Q41437), HMDH2_YEAST (P12684), HMDH3_HEVBR (Q00583), HMDH3_ORYSJ (Q9XHL5), HMDH3_SOLTU (Q41438), HMDH_AERPE (Q9YAS4), HMDH_AGRIP (O76819), HMDH_ARCFU (O28538), HMDH_ASPTE (Q9Y7D2), HMDH_ASPTN (Q0C8L9), HMDH_BLAGE (P54960), HMDH_BOVIN (A7Z064), HMDH_CAMAC (P48021), HMDH_CANAL (A0A1D8PD39), HMDH_CATRO (Q03163), HMDH_CRIGR (P00347), HMDH_CYBJA (O74164), HMDH_DROME (P14773), HMDH_GANLU (B2KX91), HMDH_GIBF5 (S0DQM8), HMDH_GIBFU (P0CT44), HMDH_HALS3 (B0R6J9), HMDH_HALVD (Q59468), HMDH_HUMAN (P04035), HMDH_MAIZE (O24594), HMDH_MESAU (P09610), HMDH_METJA (Q58116), HMDH_MOUSE (Q01237), HMDH_NICSY (Q01559), HMDH_PHYB8 (Q12649), HMDH_PIG(Q1W675), HMDH_PONAB (Q5R6N3), HMDH_PYRAB (Q9V1R3), HMDH_PYRHO (O59469), HMDH_RABIT (Q29512), HMDH_RAT(P51639), HMDH_SACS2 (O08424), HMDH_SCHMA (P16237), HMDH_SCHPO (Q10283), HMDH_STRPU (P16393), HMDH_XENLA (P20715), HMGR1_CANSA (A0A7J6H013), HMGR1_PANGI (A0A0A1C3I2), HMGR2_CANSA (A0A803NI27), HMR2A_PANGI (A0A0A1C930), HMR2B_PANGI (U5JCC6), MLCD_PENCI (Q8J0F4), MOKG_MONPI (Q3S2U3), MVAA_PSEMV (P13702), PBCC_EMENI (C8VN86)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
2 sequences
HMDH_BORBU (O51628), HMDH_METTH (O26662) |
| UniProtKB/Swiss-Prot False positive sequences |
26 sequences
AMIC_STRPN (P0A4M7), AMIC_STRR6 (P0A4M8), ARO1_SCLS1 (A7F7H0), ARO1_SCLSC (Q5XNP0), C3390_DROME (Q7KT91), CDX4_HUMAN (O14627), CND1_MOUSE (Q8K2Z4), DHOM_METGL (P37143), DHOM_PSEAE (P29365), DHON_METGL (P37144), GBA2_HUMAN (Q9HCG7), GBA2_MOUSE (Q69ZF3), GBA2_RAT(Q5M868), HIMH_ASPJA (A0A2Z5TIQ0), INIB_MYCTO (P9WJ96), INIB_MYCTU (P9WJ97), MSRA_LACSA (Q9SEC2), MURC_ERYLH (Q2NCY9), NU4C_SYNPW (A5GP41), SECY_METJA (Q60175), SIGJ_DICDI (Q6TMJ3), SYYM_ARATH (Q9M876), SYY_MESFL (Q6F0M8), SYY_STRAW (Q829F2), THIM_DESDA (B8J4C1), Y3023_ACIAD (P70736)» more |
| PDB [Detailed view] |
38 PDB
1DQ8; 1DQ9; 1DQA; 1HW8; 1HW9; 1HWI; 1HWJ; 1HWK; 1HWL; 1QAX; 1QAY; 1R31; 1R7I; 1T02; 2Q1L; 2Q6B; 2Q6C; 2R4F; 3BGL; 3CCT; 3CCW; 3CCZ; 3CD0; 3CD5; 3CD7; 3CDA; 3CDB; 4I4B; 4I56; 4I64; 4I6A; 4I6W; 4I6Y; 7ULI; 8ECG; 8GDN; 8SZ6; 8VLQ » more |