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PROSITE entry PS00319


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General information about the entry

Entry name [info] APP_CUBD
Accession [info] PS00319
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00204

Name and characterization of the entry

Description [info] Amyloid precursor protein (APP) copper-binding (CuBD) domain signature.
Pattern [info]
G-[VT]-[EK]-[FY]-V-C-C-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 18 in 18 different sequences
Number of true positive hits 18 in 18 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
18 sequences

A4_CAEEL(Q10651), A4_CAVPO(Q60495), A4_DORPE(Q06BR2), 
A4_DROME(P14599), A4_HUMAN(P05067), A4_MACFA(P53601), 
A4_MOUSE(P12023), A4_PANTR(Q5IS80), A4_PIG  (P79307), 
A4_RAT  (P08592), A4_SAISC(Q95241), A4_TAKRU(O93279), 
A4_TETFL(O73683), APLP1_HUMAN (P51693), APLP1_MOUSE (Q03157), 
APLP2_HUMAN (Q06481), APLP2_MOUSE (Q06335), APLP2_RAT   (P15943)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
7 sequences

A4_BOVIN(Q28053), A4_CANLF(Q28280), A4_FELCA(P86906), 
A4_MACMU(P29216), A4_RABIT(Q28748), A4_SHEEP(Q28757), 
A4_URSMA(Q29149)
» more

PDB
[Detailed view]
11 PDB

1OWT; 2FJZ; 2FK1; 2FK2; 2FK3; 2FKL; 2FMA; 2M05; 3KTM; 4PWQ; 7MRN