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PROSITE entry PS00320


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General information about the entry

Entry name [info] APP_INTRA
Accession [info] PS00320
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
10-OCT-2018 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00204

Name and characterization of the entry

Description [info] Amyloid precursor protein (APP) intracellular domain signature.
Pattern [info] 
G-Y-E-N-P-T-Y-[KRS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 18 in 18 different sequences
Number of true positive hits 17 in 17 different sequences
Number of 'unknown' hits 1
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 17 sequences 

A4_CAEEL(Q10651), A4_CAVPO(Q60495), A4_DROME(P14599), 

A4_HUMAN(P05067), A4_MACFA(P53601), A4_MOUSE(P12023), 
A4_PANTR(Q5IS80), A4_PIG  (P79307), A4_RAT  (P08592), 
A4_SAISC(Q95241), A4_TAKRU(O93279), A4_TETFL(O73683), 
APLP1_HUMAN (P51693), APLP1_MOUSE (Q03157), APLP2_HUMAN (Q06481), 
APLP2_MOUSE (Q06335), APLP2_RAT   (P15943)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 7 sequences 

A4_BOVIN(Q28053), A4_CANLF(Q28280), A4_FELCA(P86906), 

A4_MACMU(P29216), A4_RABIT(Q28748), A4_SHEEP(Q28757), 
A4_URSMA(Q29149)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

A4_DORPE(Q06BR2)


				
	

	

		PDB
[Detailed view]		
		
			17 PDB
			


			1M7E; 1OQN; 1X11; 2LP1; 2ROZ; 2YSZ; 2YT0; 2YT1; 3DXC; 3DXD; 3DXE; 3SV1; 
			
				6ITU; 6IYC; 8OTF; 8X52; 8X54
			
			

			» more