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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00332


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PURL: https://purl.expasy.org/prosite/signature/PS00332

Direct ScanProsite submission
General information about the entry

Entry name [info] SOD_CU_ZN_2
Accession [info] PS00332
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00082

Name and characterization of the entry

Description [info] Copper/Zinc superoxide dismutase signature 2.
Pattern [info] 
G-[GNHD]-[SGA]-[GR]-x-R-x-[SGAWRV]-C-x(2)-[IV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 168 in 168 different sequences
Number of true positive hits 166 in 166 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 9
Number of 'partial' sequences 18
Precision (true positives / (true positives + false positives)) 98.81 %
Recall (true positives / (true positives + false negatives)) 94.86 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] disulfide at position 9
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 166 sequences 

CCS_HUMAN   (O14618), CCS_MOUSE   (Q9WU84), CCS_PIG (Q6PWT7), 

CCS_RAT (Q9JK72), SOD1A_XENLA (P13926), SOD1B_XENLA (P15107), 
SODA_TALMA  (Q19VG9), SODA_TALMQ  (B6QEB3), SODC1_AQUAE (O67149), 
SODC1_ARATH (P24704), SODC1_BRAJU (Q42611), SODC1_DEBHA (O42724), 
SODC1_MESCR (P93258), SODC1_ORYSI (A2XGP6), SODC1_ORYSJ (Q0DRV6), 
SODC1_SALT4 (E8XDJ8), SODC1_SALTY (P0CW86), SODC1_SOLLC (P14830), 
SODC2_AQUAE (O66602), SODC2_ARATH (O78310), SODC2_BRAJU (Q42612), 
SODC2_MAIZE (P11428), SODC2_MESCR (O49044), SODC2_OLEEU (Q8L5E0), 
SODC2_ORYSJ (P28757), SODC2_SOLLC (Q43779), SODC3_ARATH (Q9FK60), 
SODC4_MAIZE (P23345), SODC5_DICDI (Q54G70), SODC5_MAIZE (P23346), 
SODC6_DICDI (Q54TW8), SODCP_MEDSA (O65198), SODCP_ORYSJ (P93407), 
SODCP_PEA   (P11964), SODCP_PETHY (P10792), SODCP_PINSY (P24707), 
SODCP_POPTM (P36214), SODCP_SOLCS (O04997), SODCP_SOLLC (P14831), 
SODCP_SPIOL (P07505), SODCP_VITVI (O65199), SODCP_ZANAE (O65175), 
SODC_ACTPL  (P24702), SODC_ANACO  (Q9SQL5), SODC_ASPFL  (Q8X1S6), 
SODC_ASPFU  (Q9Y8D9), SODC_ASPNC  (A2QMY6), SODC_ASPNG  (P85978), 
SODC_ASPOR  (Q877B5), SODC_BOMMO  (P82205), SODC_BOSMU  (Q52RN5), 
SODC_BOTFU  (Q70Q35), SODC_BOVIN  (P00442), SODC_BRAOC  (P09678), 
SODC_BRUAB  (P15453), SODC_BRUME  (P66826), SODC_BRUPA  (P41962), 
SODC_BRUSU  (P66827), SODC_CAEBR  (A8XCP3), SODC_CAEEL  (P34697), 
SODC_CALJA  (Q8HXP8), SODC_CAMDR  (H6BDU4), SODC_CANAX  (O59924), 
SODC_CANGA  (Q6FWL5), SODC_CANLF  (Q8WNN6), SODC_CAPAN  (O22373), 
SODC_CARCR  (P80174), SODC_CARPA  (O65768), SODC_CAUVC  (P20379), 
SODC_CAVPO  (P33431), SODC_CERCA  (P28755), SODC_CEREL  (O46412), 
SODC_CHICK  (P80566), SODC_CHYAM  (Q07182), SODC_CLAP2  (Q96VL0), 
SODC_COLGL  (O94178), SODC_CORMI  (Q8J0N2), SODC_CORTN  (Q8J0N3), 
SODC_CRYGA  (Q9C0N4), SODC_CRYNH  (J9VLJ9), SODC_DANRE  (O73872), 
SODC_DROBS  (P54407), SODC_DROER  (Q9U4X4), SODC_DROMA  (P61853), 
SODC_DROME  (P61851), SODC_DROOR  (Q9U4X5), SODC_DROPS  (Q95086), 
SODC_DROSE  (P61854), SODC_DROSI  (P61852), SODC_DROTE  (Q9U4X2), 
SODC_DROVI  (P10791), SODC_DROWI  (P41973), SODC_DROYA  (Q9U4X3), 
SODC_ECO57  (P0AGD2), SODC_ECOLI  (P0AGD1), SODC_EMENI  (Q9HEY7), 
SODC_EREGS  (Q751L8), SODC_FRATH  (Q59448), SODC_HAEDU  (Q59452), 
SODC_HAEIF  (P25841), SODC_HAEPA  (P25842), SODC_HALRO  (P81926), 
SODC_HORSE  (P00443), SODC_HUMAN  (P00441), SODC_HUMLT  (P83684), 
SODC_HYLLA  (Q8HXQ3), SODC_IPOBA  (Q07796), SODC_KLULA  (Q6CPE2), 
SODC_LEGPH  (Q5ZT17), SODC_LEGPN  (P69049), SODC_MACFA  (Q8HXQ1), 
SODC_MACFU  (Q8HXQ2), SODC_MACMU  (Q8HXQ0), SODC_MOUSE  (P08228), 
SODC_MYCBO  (P0A609), SODC_MYCLE  (Q9CBI6), SODC_MYCPA  (Q9AGW2), 
SODC_MYCTO  (P9WGE8), SODC_MYCTU  (P9WGE9), SODC_NEIMA  (P57005), 
SODC_NEIMB  (Q59623), SODC_NEUCR  (P07509), SODC_NICPL  (P27082), 
SODC_NPVAC  (P24705), SODC_NPVOP  (O12933), SODC_ONCVO  (P24706), 
SODC_PANGI  (O22668), SODC_PANTR  (P60052), SODC_PASMU  (Q59689), 
SODC_PBCV1  (Q90023), SODC_PEA(Q02610), SODC_PHOLE  (P00446), 
SODC_PIG(P04178), SODC_PINSY  (P24669), SODC_PLESN  (Q6T3B0), 
SODC_PODAS  (Q711T9), SODC_PONPY  (Q8HXQ4), SODC_PRIGL  (P11418), 
SODC_RABIT  (P09212), SODC_RAMVA  (A0A1D1VU85), SODC_RAT(P07632), 
SODC_SALTY  (O68901), SODC_SAPAP  (Q8HXP9), SODC_SCHMA  (Q01137), 
SODC_SCHPO  (P28758), SODC_SHEEP  (P09670), SODC_SOLCS  (O04996), 
SODC_SOYBN  (Q7M1R5), SODC_SPIOL  (P22233), SODC_XENTR  (Q0IIW3), 
SODC_XIPGL  (P03946), SODC_YARLI  (Q6C662), SODC_YEAST  (P00445), 
SODC_ZANAE  (O65174), SODC_ZINOF  (C0HK70), SODE_BRUPA  (P41963), 
SODE_CAEEL  (P34461), SODE_DIRIM  (P41974), SODE_DROME  (Q7JR71), 
SODE_HAECO  (P51547), SODE_HUMAN  (P08294), SODE_MOUSE  (O09164), 
SODE_ONCVO  (Q07449), SODE_RABIT  (P41975), SODE_RAT(Q08420), 
SODE_SCHMA  (P16026)
» more

UniProtKB/Swiss-Prot
False negative sequences		 9 sequences 

CCS1_DEBHA  (Q6BK66), CCS_DICDI   (Q54F73), SODC2_DICDI (Q54RN1), 

SODC3_DICDI (Q54RQ1), SODC_ASPJA  (Q12548), SODC_DEIRA  (Q9RU48), 
SODC_HAECO  (Q27666), SODC_PAUKA  (O49073), YOJM_BACSU  (O31851)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 18 sequences 

SODC1_OLEEU (P80740), SODC2_DEBHN (P82902), SODC2_PICAB (P29428), 

SODCP_PICAB (P29427), SODCP_PINPS (P81082), SODC_AGGAC  (Q59081), 
SODC_AQUCT  (P23417), SODC_DROMD  (Q95081), SODC_DROMI  (Q95079), 
SODC_DROOB  (Q95085), SODC_DROPB  (Q95087), SODC_DROPE  (Q95088), 
SODC_DROTO  (Q95095), SODC_HORVU  (P34936), SODC_LAMCR  (P81036), 
SODC_MANHA  (Q51853), SODC_PAROL  (P83129), SODC_STRHE  (P81163)
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

BURS_PERAM  (P84118), STT3A_ORYSJ (Q6F2Z1)


				
	

	

		PDB
[Detailed view]		
		
			214 PDB
			


			pdb_00001azv; pdb_00001b4l; pdb_00001b4t; pdb_00001ba9; pdb_00001bzo; pdb_00001cb4; pdb_00001cbj; pdb_00001cob; pdb_00001do5; pdb_00001dsw; pdb_00001e9o; pdb_00001e9p; 
			
				pdb_00001e9q; pdb_00001eqw; pdb_00001eso; pdb_00001f18; pdb_00001f1a; pdb_00001f1d; pdb_00001f1g; pdb_00001fun; pdb_00001hl4; pdb_00001hl5; pdb_00001ib5; pdb_00001ibb; 
				pdb_00001ibd; pdb_00001ibf; pdb_00001ibh; pdb_00001jcv; pdb_00001jk9; pdb_00001kmg; pdb_00001l3n; pdb_00001mfm; pdb_00001n18; pdb_00001n19; pdb_00001oaj; pdb_00001oal; 
				pdb_00001oez; pdb_00001ozt; pdb_00001ozu; pdb_00001p1v; pdb_00001ptz; pdb_00001pu0; pdb_00001pzs; pdb_00001q0e; pdb_00001rk7; pdb_00001sda; pdb_00001sdy; pdb_00001sos; 
				pdb_00001spd; pdb_00001srd; pdb_00001sxa; pdb_00001sxb; pdb_00001sxc; pdb_00001sxn; pdb_00001sxs; pdb_00001sxz; pdb_00001to4; pdb_00001to5; pdb_00001uxl; pdb_00001uxm; 
				pdb_00001xso; pdb_00001yai; pdb_00001yaz; pdb_00001yso; pdb_00001z9n; pdb_00001z9p; pdb_00002aeo; pdb_00002af2; pdb_00002aps; pdb_00002aqn; pdb_00002aqp; pdb_00002aqq; 
				pdb_00002aqr; pdb_00002aqs; pdb_00002aqt; pdb_00002c9s; pdb_00002c9u; pdb_00002c9v; pdb_00002gbt; pdb_00002jcw; pdb_00002jlp; pdb_00002lu5; pdb_00002nam; pdb_00002nnx; 
				pdb_00002r27; pdb_00002sod; pdb_00002v0a; pdb_00002vr6; pdb_00002vr7; pdb_00002vr8; pdb_00002wko; pdb_00002wyt; pdb_00002wyz; pdb_00002wz0; pdb_00002wz5; pdb_00002wz6; 
				pdb_00002xjk; pdb_00002xjl; pdb_00002z7u; pdb_00002z7w; pdb_00002z7y; pdb_00002z7z; pdb_00002zkw; pdb_00002zkx; pdb_00002zky; pdb_00002zow; pdb_00003cqp; pdb_00003cqq; 
				pdb_00003ecu; pdb_00003ecv; pdb_00003ecw; pdb_00003gqf; pdb_00003gtt; pdb_00003gtv; pdb_00003gzo; pdb_00003gzp; pdb_00003gzq; pdb_00003h2p; pdb_00003h2q; pdb_00003hff; 
				pdb_00003hog; pdb_00003hw7; pdb_00003k91; pdb_00003kbe; pdb_00003kbf; pdb_00003kh3; pdb_00003kh4; pdb_00003km1; pdb_00003km2; pdb_00003l9e; pdb_00003l9y; pdb_00003ltv; 
				pdb_00003mkg; pdb_00003pu7; pdb_00003qqd; pdb_00003re0; pdb_00003s0p; pdb_00003sod; pdb_00003t5w; pdb_00004a7g; pdb_00004a7q; pdb_00004a7s; pdb_00004a7t; pdb_00004a7u; 
				pdb_00004a7v; pdb_00004b3e; pdb_00004bcy; pdb_00004ff9; pdb_00004l05; pdb_00004mcm; pdb_00004mcn; pdb_00005in2; pdb_00005k02; pdb_00005o3y; pdb_00005o40; pdb_00005u9m; 
				pdb_00005yto; pdb_00005ytu; pdb_00005yul; pdb_00006a9o; pdb_00006d52; pdb_00006dtk; pdb_00006ffk; pdb_00006fn8; pdb_00006fol; pdb_00006fon; pdb_00006fp6; pdb_00006spa; 
				pdb_00006sph; pdb_00006spi; pdb_00006spj; pdb_00006spk; pdb_00006vbs; pdb_00006vbt; pdb_00006z3v; pdb_00006z4g; pdb_00006z4h; pdb_00006z4i; pdb_00006z4j; pdb_00006z4k; 
				pdb_00006z4l; pdb_00006z4m; pdb_00006z4o; pdb_00007fb9; pdb_00007nxx; pdb_00007t8e; pdb_00007t8f; pdb_00007t8g; pdb_00007t8h; pdb_00007vzf; pdb_00007wwt; pdb_00007wwy; 
				pdb_00007wx0; pdb_00007wx1; pdb_00007xx3; pdb_00007ypp; pdb_00007ypr; pdb_00008ccx; pdb_00008gsq; pdb_00008ihu; pdb_00008ihv; pdb_00008iq0; pdb_00008iq1; pdb_00008k33; 
				pdb_00008k3a; pdb_00008k3l; pdb_00008q6m; pdb_00008yat; pdb_00008yd3; pdb_00008zd5; pdb_00008zd6; pdb_00009iyk; pdb_00009jbo; pdb_00009jbp
			
			

			» more