PROSITE entry PS00333

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

Entry name [info]	DNA_LIGASE_A2
Accession [info]	PS00333
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00295

Name and characterization of the entry

Description [info]	ATP-dependent DNA ligase signature 2.
Pattern [info]	E-G-[LIVMA]-[LIVM]-[LIVMA]-[KR]-x(5,8)-[YW]-[QNEKTI]-x(2,6)-[KRH]-x(3,5)- K-[LIVMFY]-K.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.

Total number of hits	106 in 106 different sequences
Number of true positive hits	106 in 106 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	54
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	66.25 %

Comments [info]

Taxonomic range [info]	Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	1
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

106 sequences

DNLI1_ARATH (Q42572), DNLI1_CAEEL (Q27474), DNLI1_DICDI (Q869E1),

DNLI1_DROME (Q9W1H4), DNLI1_HALWD (Q18HT7), DNLI1_HUMAN (P18858), 
DNLI1_KORCO (B1L3K8), DNLI1_MOUSE (P37913), DNLI1_RAT   (Q9JHY8), 
DNLI1_SCHPO (P12000), DNLI1_XENLA (P51892), DNLI1_YEAST (P04819), 
DNLI2_KORCO (B1L3V2), DNLI3_DICDI (Q54QM4), DNLI3_HUMAN (P49916), 
DNLI3_MOUSE (P97386), DNLI4_ARATH (Q9LL84), DNLI4_CANAL (P52496), 
DNLI4_CHICK (Q90YB1), DNLI4_COPC7 (A8N936), DNLI4_COPCI (Q7Z7W5), 
DNLI4_CRIGR (G3GTP0), DNLI4_CRYNB (P0CN09), DNLI4_CRYNJ (P0CN08), 
DNLI4_HUMAN (P49917), DNLI4_MOUSE (Q8BTF7), DNLI4_ORYSJ (Q7X7E9), 
DNLI4_PONAB (Q5R6L3), DNLI4_YEAST (Q08387), DNLI_ACIAM  (Q02093), 
DNLI_AERPE  (Q9YD18), DNLI_ANAD2  (B8JBM1), DNLI_ANADE  (Q2IH69), 
DNLI_ANADF  (A7HID3), DNLI_ANASK  (B4UIS1), DNLI_ARCFU  (O29632), 
DNLI_ASFB7  (P35970), DNLI_ASFK5  (P0C992), DNLI_ASFM2  (P26813), 
DNLI_ASFP4  (P0C990), DNLI_ASFWA  (P0C991), DNLI_BEUC1  (C5BW79), 
DNLI_BPT3   (P07717), DNLI_BPT4   (P00970), DNLI_BPT6   (P19088), 
DNLI_BPT7   (P00969), DNLI_DICT6  (B5YD88), DNLI_DICTD  (B8DZX8), 
DNLI_HAEIN  (P44121), DNLI_HYPBU  (A2BJX6), DNLI_IGNH4  (A8AB20), 
DNLI_META3  (A6UVC4), DNLI_METB6  (A7IAA9), DNLI_METHJ  (Q2FTH4), 
DNLI_METJA  (Q57635), DNLI_METKA  (Q8TWN3), DNLI_METM5  (A4FY19), 
DNLI_METM6  (A9AAX4), DNLI_METM7  (A6VFQ9), DNLI_METMJ  (A3CWP1), 
DNLI_METMP  (Q6LYM1), DNLI_METS3  (A5UKX2), DNLI_METS5  (A4YD25), 
DNLI_METTF  (P54875), DNLI_METTH  (Q50566), DNLI_METTP  (A0B7F9), 
DNLI_METVS  (A6UNY0), DNLI_MONPV  (A0A7H0DNE6), DNLI_MYCA1  (A0QJL0), 
DNLI_MYCGI  (A4TDS2), DNLI_MYCPA  (Q73V97), DNLI_MYCS2  (A0QUP1), 
DNLI_MYCSJ  (A3PXE2), DNLI_MYCSK  (A1UDY9), DNLI_MYCSS  (Q1BB26), 
DNLI_MYCVP  (A1T6P2), DNLI_NITMS  (A9A3K1), DNLI_NOCSJ  (A1SKL2), 
DNLI_OPITP  (B1ZZL9), DNLI_PYRAB  (P0CL75), DNLI_PYRAY  (P0CL74), 
DNLI_PYRFU  (P56709), DNLI_PYRHO  (O59288), DNLI_SACS2  (Q980T8), 
DNLI_SACSH  (Q9P9K9), DNLI_SORC5  (A9GU24), DNLI_STAMF  (A3DP49), 
DNLI_SULAC  (Q4JAM1), DNLI_SULIA  (C3MZR1), DNLI_SULIK  (C4KIZ2), 
DNLI_SULIL  (C3MJ14), DNLI_SULIM  (C3MYD2), DNLI_SULIN  (C3NF77), 
DNLI_SULIY  (C3N834), DNLI_SULTO  (Q976G4), DNLI_SULZI  (D2CJS7), 
DNLI_THEAC  (Q9HJ26), DNLI_THEFM  (Q9HH07), DNLI_THEKO  (Q9HHC4), 
DNLI_THEON  (B6YTR4), DNLI_THEVO  (Q979A1), DNLI_VACCA  (O57250), 
DNLI_VACCC  (P20492), DNLI_VACCW  (P16272), DNLI_VAR67  (P0DOO3), 
DNLI_VARV   (P0DOO4)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

54 sequences

DNLI1_METAC (Q8TSR7), DNLI1_METBF (Q46C04), DNLI1_METMA (Q8PVR7),

DNLI1_THEPD (A1RXA6), DNLI2_HALWD (Q18GX5), DNLI2_METAC (Q8TMT1), 
DNLI2_METBF (Q46BA3), DNLI2_METMA (Q8PTK1), DNLI2_THEPD (A1RY72), 
DNLI3_SCHPO (Q9C1W9), DNLI4_SCHPO (O74833), DNLI_AQUAE  (O67398), 
DNLI_CALMQ  (A8MDU6), DNLI_CENSY  (A0RWD6), DNLI_FOWPN  (Q67480), 
DNLI_HALLT  (B9LUZ9), DNLI_HALMA  (Q5V4R0), DNLI_HALS3  (B0R4C9), 
DNLI_HALSA  (Q9HR35), DNLI_HALVD  (D4GYZ4), DNLI_KINRD  (A6WG40), 
DNLI_KORVE  (Q1II25), DNLI_METAR  (Q0W0X1), DNLI_METBU  (Q12X08), 
DNLI_METLZ  (A2SR38), DNLI_METPE  (B8GGB8), DNLI_METST  (Q2NHF9), 
DNLI_MYCBO  (Q7TTR7), DNLI_MYCBP  (A1KN60), DNLI_MYCBT  (C1AGI1), 
DNLI_MYCMM  (B2HHE1), DNLI_MYCTA  (A5U776), DNLI_MYCTO  (P9WNV4), 
DNLI_MYCTU  (P9WNV5), DNLI_MYCUA  (A0PTC0), DNLI_NANEQ  (Q74M64), 
DNLI_NATPD  (Q3IPX0), DNLI_NOCFA  (Q5YNY7), DNLI_NPVLD  (Q9YMV2), 
DNLI_PERMH  (C0QSL7), DNLI_PICTO  (Q6L195), DNLI_PSECP  (B8HCE1), 
DNLI_PYRAE  (O93723), DNLI_PYRAR  (A4WH24), DNLI_PYRCJ  (A3MS62), 
DNLI_PYRIL  (A1RTK4), DNLI_PYRNV  (B1YA52), DNLI_RHOJR  (Q0SG75), 
DNLI_RHOOB  (C1AX87), DNLI_SACEN  (A4F870), DNLI_STRAW  (Q826P6), 
DNLI_STRCO  (Q9FCB1), DNLI_STRGG  (B1W5J2), LIGD_BACSU  (O34398)

» more

PDB
[Detailed view]

51 PDB

1A0I; 1X9N; 2CFM; 2HIV; 2HIX; 3GDE; 3L2P; 3W1B; 3W1G; 3W5O; 6BKF; 6BKG; 6DT1; 6IMJ; 6IMK; 6IML; 6IMN; 6P09; 6P0A; 6P0B; 6P0C; 6P0D; 6P0E; 6Q1V; 7KR3; 7KR4; 7L34; 7L35; 7LSY; 7LT3; 7NFC; 7NFE; 7QNZ; 7QO1; 7RPO; 7RPW; 7RPX; 7SUM; 7SX5; 7SXE; 8BH3; 8BHV; 8BHY; 8BOT; 8EZA; 8EZB; 8VDN; 8VDS; 8VDT; 8VZL; 8VZM
» more