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PROSITE entry PS00347


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PURL: https://purl.expasy.org/prosite/signature/PS00347

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General information about the entry

Entry name [info] ZF_PARP_1
Accession [info] PS00347
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00360

Name and characterization of the entry

Description [info] Zinc finger poly(ADP-ribose) polymerase (PARP)-type signature.
Pattern [info] 
C-[KR]-x-C-x(3)-I-x-[KAL]-x(3)-[RG]-x(16,18)-W-[FYH]-H-x(2)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 21 in 13 different sequences
Number of true positive hits 21 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 6
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 77.78 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Site [info] zinc(?) at position 1
Site [info] zinc(?) at position 4
Site [info] zinc(?) at position 14
Site [info] zinc(?) at position 16
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 13 sequences 

DNLI3_HUMAN (P49916), DNLI3_MOUSE (P97386), PARP1_BOVIN (P18493), 

PARP1_CAEEL (Q9N4H4), PARP1_CHICK (P26446), PARP1_CRIGR (Q9R152), 
PARP1_DANRE (Q5RHR0), PARP1_HUMAN (P09874), PARP1_MOUSE (P11103), 
PARP1_RAT   (P27008), PARP1_XENLA (P31669), PARP_DROME  (P35875), 
PARP_SARPE  (Q11208)
» more

UniProtKB/Swiss-Prot
False negative sequences		 6 sequences 

PARP1_ARATH (Q9ZP54), PARP1_MAIZE (Q9ZSV1), PARP1_ORYSJ (Q7EYV7), 

YEU7_SCHPO  (O13706), YGI7_SCHPO  (Q9Y7K9), ZDP_ARATH   (Q84JE8)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PARP1_ONCMA (Q08824)


				
	

	

		PDB
[Detailed view]		
		
			20 PDB
			


			1UW0; 2CS2; 2DMJ; 2L30; 2L31; 2N8A; 3OD8; 3ODA; 3ODC; 3ODE; 4AV1; 4DQY; 
			
				4OPX; 4OQA; 4OQB; 7S68; 7S6H; 7S6M; 7S81; 8G0H
			
			

			» more