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PROSITE entry PS00356


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General information about the entry

Entry name [info] HTH_LACI_1
Accession [info] PS00356
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00366

Name and characterization of the entry

Description [info] LacI-type HTH domain signature.
Pattern [info]
[LIVM]-x-[DE]-[LIVM]-A-x(2)-[STAGV]-x-V-[GSTP]-x(2)-[STAG]-[LIVMA]-x(2)-
[LIVMFYAN]-[LIVMC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 185 in 185 different sequences
Number of true positive hits 179 in 179 different sequences
Number of 'unknown' hits 0
Number of false positive hits 6 in 6 different sequences
Number of false negative sequences 11
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 96.76 %
Recall (true positives / (true positives + false negatives)) 94.21 %

Comments [info]

Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
179 sequences

ASCG_ECOLI  (P24242), CCPA_BACSU  (P25144), CCPA_PRIMG  (P46828), 
CCPA_STAAC  (Q5HF38), CCPA_STAAM  (P67655), CCPA_STAAN  (P99175), 
CCPA_STAAR  (Q6GFX2), CCPA_STAAS  (Q6G8J1), CCPA_STAAW  (Q8NW33), 
CCPA_STAEQ  (Q5HNH3), CCPA_STAES  (Q8CNV8), CCPA_STAXY  (Q56194), 
CCPA_STRMU  (O07329), CCPB_BACSU  (P37517), CRA_ECO57   (P0ACP3), 
CRA_ECOL6   (P0ACP2), CRA_ECOLI   (P0ACP1), CRA_SALTI   (P0A2P9), 
CRA_SALTY   (P0A2P8), CRA_SHIFL   (P0ACP4), CSCR_ECOLX  (P62604), 
CSCR_SHIFL  (P62572), CYTR_ECO57  (P0ACN9), CYTR_ECOL6  (P0ACN8), 
CYTR_ECOLI  (P0ACN7), CYTR_SHIFL  (P0ACP0), DEGA_BACSU  (P37947), 
EBGR_ECOLI  (P06846), ENDR_PAEPO  (P27871), EXUR_BACSU  (Q9JMQ1), 
FRUR_VIBCH  (Q9KM69), GALR_ECOLI  (P03024), GALR_HAEIN  (P31766), 
GALR_LACCA  (O84905), GALR_SALTS  (E1WAQ4), GALR_SALTY  (P0CL11), 
GALR_STRTR  (Q9ZB11), GALS_ECOLI  (P25748), GALS_SALTY  (P41030), 
GLK_BURL3   (Q39IQ1), GLK_BURO1   (Q1BYA7), GLK_BURP1   (Q3JPP0), 
GLK_BURPS   (Q63RQ7), GLK_BURTA   (Q2SYA5), GLK_PARXL   (Q143F8), 
GNTR_ECOL6  (P0ACP6), GNTR_ECOLI  (P0ACP5), GNTR_PSEAE  (Q9I1F6), 
IDNR_ECOLI  (P39343), IRRE_DEIDV  (C1CZ84), IRRE_DEIRA  (Q9RXY7), 
KDGR_BACSU  (P50844), LACI_ECOLI  (P03023), LACI_KLEPN  (P06220), 
MALI_ECOLI  (P18811), MALI_VIBFU  (P96158), MALR_CLOBU  (O05103), 
MALR_STAXY  (Q56201), MALR_STRCO  (P72396), MALR_STRPN  (P0A4T1), 
MALR_STRR6  (P0A4T2), MELR_BACSU  (O34829), NFXB_PSEAE  (P32265), 
PEPR_LACDL  (Q48544), PTXS_PSEDL  (A0A167V873), PTXS_PSEPK  (Q88HH7), 
PURR_ACTP2  (A3N0H9), PURR_ACTP7  (B3H1F6), PURR_ACTPJ  (B0BP99), 
PURR_ACTSZ  (A6VNL0), PURR_ALIF1  (Q5E4H9), PURR_ALIFM  (B5FF00), 
PURR_ALISL  (B6EH86), PURR_CROS8  (A7MFD3), PURR_ECO24  (A7ZMC4), 
PURR_ECO27  (B7URZ9), PURR_ECO45  (B7MA12), PURR_ECO55  (B7L5L1), 
PURR_ECO57  (P0ACP8), PURR_ECO5E  (B5Z492), PURR_ECO7I  (B7NTX5), 
PURR_ECO81  (B7MVD4), PURR_ECO8A  (B7M0L5), PURR_ECOBW  (C4ZYC2), 
PURR_ECOHS  (A8A0K5), PURR_ECOK1  (A1ABJ9), PURR_ECOL5  (Q0THG9), 
PURR_ECOL6  (Q8FH72), PURR_ECOLC  (B1IQ96), PURR_ECOLI  (P0ACP7), 
PURR_ECOLU  (B7NBB1), PURR_ECOSE  (B6IB98), PURR_ECOSM  (B1LEM6), 
PURR_ECOUT  (Q1RBD7), PURR_EDWI9  (C5BE45), PURR_ERWT9  (B2VEM5), 
PURR_ESCF3  (B7LQA9), PURR_GLAP5  (B8F4D0), PURR_HAEDU  (Q7VL44), 
PURR_HAEI8  (Q4QL70), PURR_HAEIE  (A5UCM9), PURR_HAEIG  (A5UIZ0), 
PURR_HAEIN  (P46456), PURR_HISS1  (Q0I4B4), PURR_HISS2  (B0UUN7), 
PURR_KLEP3  (B5XWL8), PURR_KLEP7  (A6TA06), PURR_MANSM  (Q65TP0), 
PURR_PASMU  (Q9CN88), PURR_PECAS  (Q6D5W3), PURR_PECCP  (C6DK36), 
PURR_PHOLL  (Q7N3V8), PURR_PHOPR  (Q6LQB9), PURR_PROMH  (B4EWM9), 
PURR_SALA4  (B5F6L7), PURR_SALAR  (A9MEJ1), PURR_SALCH  (Q57PK6), 
PURR_SALDC  (B5FIH3), PURR_SALEP  (B5QV29), PURR_SALG2  (B5RAM9), 
PURR_SALHS  (B4TH70), PURR_SALNS  (B4T567), PURR_SALPA  (Q5PH15), 
PURR_SALPB  (A9N0Y2), PURR_SALPC  (C0Q5V2), PURR_SALPK  (B5BKD9), 
PURR_SALSV  (B4TUY8), PURR_SALTI  (Q8Z6P1), PURR_SALTY  (O68446), 
PURR_SERP5  (A8GDV6), PURR_SHIB3  (B2U2G3), PURR_SHIBS  (Q321B7), 
PURR_SHIDS  (Q32FB3), PURR_SHIF8  (Q0T4B4), PURR_SHIFL  (P0ACP9), 
PURR_SHISS  (Q3Z213), PURR_VIBA3  (B7VMG4), PURR_VIBC1  (A7N1L2), 
PURR_VIBC3  (A5F7H0), PURR_VIBCH  (Q9KRC1), PURR_VIBCM  (C3LN44), 
PURR_VIBPA  (Q87QW9), PURR_VIBVU  (Q8DAQ5), PURR_VIBVY  (Q7MJ57), 
PURR_YERE8  (A1JP52), PURR_YERP3  (A7FHK2), PURR_YERPA  (Q1C774), 
PURR_YERPB  (B2K5I4), PURR_YERPE  (Q7CIS2), PURR_YERPG  (A9QZB3), 
PURR_YERPN  (Q1CIL0), PURR_YERPP  (A4TIQ4), PURR_YERPS  (Q66A32), 
PURR_YERPY  (B1JJ59), RBSR_BACSU  (P36944), RBSR_ECO57  (P0ACQ2), 
RBSR_ECOL6  (P0ACQ1), RBSR_ECOLI  (P0ACQ0), RBSR_HAEIN  (P44329), 
RBSR_HALH5  (Q9K6K2), RBSR_PASMU  (Q9CPA2), RBSR_SHIFL  (P0ACQ3), 
RBTR_KLEAE  (P07760), REG1_STRLI  (P72469), REGA_CLOAB  (P58258), 
REGA_CLOSA  (Q45831), SACR_LACLL  (Q04939), SCRR_KLEPN  (P37076), 
SCRR_PEDPE  (P43472), SCRR_SALTM  (P37077), SCRR_STAXY  (P74892), 
SCRR_STRMU  (Q54430), SCRR_VIBAL  (P24508), TRER_ECOLI  (P36673), 
TRER_SALTY  (P36674), YAML_STRLM  (P23823), YCJW_ECOLI  (P77615), 
YKVZ_BACSU  (O31690), YVDE_BACSU  (O06987)
» more

UniProtKB/Swiss-Prot
False negative sequences
11 sequences

AGLR_RHIME  (Q9Z3R4), CELR_THEFU  (O87590), GANR_BACSU  (O07008), 
IPSA_CORGL  (Q8NMF0), LACR_LACHE  (Q7WTB0), NTDR_BACSU  (O07567), 
PECTR_LACP7 (A9KNI6), PTXS_PSEAE  (G3XD97), RAFR_ECOLX  (P21867), 
RBSR_LACLA  (Q9CF41), Y4158_STRCO (Q05954)
» more

UniProtKB/Swiss-Prot
False positive sequences
6 sequences

LOGH_MYCMM  (B2HS63), MDH_BACTN   (Q8A0W0), RPOB_CHRFK  (A0M3Y9), 
S29A3_BOVIN (A1A4N1), Y1018_STRA3 (P67251), Y983_STRA5  (P67252)
» more

PDB
[Detailed view]
61 PDB

1BDH; 1BDI; 1CJG; 1EFA; 1JFS; 1JFT; 1JH9; 1JWL; 1JYE; 1JYF; 1L1M; 1LBG; 1LBH; 1LBI; 1LCC; 1LCD; 1LQC; 1OSL; 1PNR; 1PRU; 1PRV; 1QP0; 1QP4; 1QP7; 1QPZ; 1QQA; 1QQB; 1RZR; 1UXC; 1UXD; 1VPW; 1WET; 1ZAY; 1ZVV; 2BJC; 2HSG; 2JCG; 2KEI; 2KEJ; 2KEK; 2LCV; 2PE5; 2PUA; 2PUB; 2PUC; 2PUD; 2PUE; 2PUF; 2PUG; 3DBI; 3DTE; 3DTI; 3DTK; 3EDC; 3OQM; 3OQN; 3OQO; 4RZS; 4RZT; 7E5W; 7X7H
» more