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PROSITE entry PS00399


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General information about the entry

Entry name [info] SUCCINYL_COA_LIG_2
Accession [info] PS00399
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00335

Name and characterization of the entry

Description [info] ATP-citrate lyase / succinyl-CoA ligases family active site.
Pattern [info] 
G-x(2)-A-x(4,7)-[RQT]-[LIVMF]-G-H-[AS]-[GH].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 66 in 66 different sequences
Number of true positive hits 64 in 64 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 96.97 %
Recall (true positives / (true positives + false negatives)) 86.49 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] phosphorylation at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 64 sequences 

ACL1_NEUCR  (Q8X097), ACL1_SORMK  (O93988), ACLB1_ARATH (Q9C522), 

ACLB1_ORYSJ (Q93VT8), ACLB2_ARATH (Q9FGX1), ACLY_BOVIN  (Q32PF2), 
ACLY_CAEEL  (P53585), ACLY_DICDI  (Q54YA0), ACLY_HUMAN  (P53396), 
ACLY_MOUSE  (Q91V92), ACLY_RAT(P16638), ACLY_SHEEP  (Q2TCH3), 
MTKB_METEA  (P53595), SAUD_BILW3  (E5Y8P7), SUCA1_ARATH (P68209), 
SUCA1_SOLLC (Q8GTQ9), SUCA1_TRIVA (P53399), SUCA2_ARATH (Q8LAD2), 
SUCA2_SOLLC (Q6DQL1), SUCA2_TRIVA (P53400), SUCA3_TRIVA (P53401), 
SUCA_BLAHN  (B3FHT4), SUCA_BOVIN  (Q58DR8), SUCA_CAEEL  (P53596), 
SUCA_COLLI  (Q9YGD2), SUCA_DICDI  (P36967), SUCA_DROME  (Q94522), 
SUCA_HUMAN  (P53597), SUCA_MOUSE  (Q9WUM5), SUCA_NEUCR  (Q9P727), 
SUCA_ORYSJ  (Q6ZL94), SUCA_PIG(O19069), SUCA_RAT(P13086), 
SUCA_SCHPO  (O13750), SUCA_YEAST  (P53598), SUCD1_ARCFU (O28733), 
SUCD2_ARCFU (O28098), SUCD_AQUAE  (O67547), SUCD_BACSU  (P80865), 
SUCD_COXBU  (P53591), SUCD_ECO57  (P0AGF1), SUCD_ECOL6  (P0AGF0), 
SUCD_ECOLI  (P0AGE9), SUCD_HAEIN  (P45102), SUCD_METJA  (Q58643), 
SUCD_METTH  (O26663), SUCD_MYCBO  (Q7U0Z0), SUCD_MYCTO  (P9WGC6), 
SUCD_MYCTU  (P9WGC7), SUCD_PSEAE  (Q51567), SUCD_RICBR  (Q1RH56), 
SUCD_RICCN  (Q92I22), SUCD_RICFE  (Q4ULQ8), SUCD_RICPR  (O08371), 
SUCD_RICTY  (Q9AKE1), SUCD_STAAC  (Q5HGI6), SUCD_STAAM  (P66866), 
SUCD_STAAN  (P99070), SUCD_STAAR  (Q6GHI9), SUCD_STAAS  (Q6G9W7), 
SUCD_STAAW  (Q8NX01), SUCD_STAEQ  (Q5HPU4), SUCD_STAES  (Q8CPH4), 
SUCD_THETH  (P09143)
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

ACL1_SCHPO  (Q9P7W3), ACL2_SCHPO  (O13907), ACLA1_ARATH (Q9SGY2), 

ACLA1_ORYSJ (Q53JY8), ACLA2_ARATH (O22718), ACLA2_ORYSJ (Q2QZ86), 
ACLA3_ARATH (O80526), ACLA3_ORYSJ (Q2QNG7), SQWL_ACHSX  (A0A3A6N9V6), 
SUCB_SOLLC  (Q84LB6)
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

ATG26_CRYNB (P0CN91), ATG26_CRYNJ (P0CN90)


				
	

	

		PDB
[Detailed view]		
		
			63 PDB
			


			1CQI; 1CQJ; 1EUC; 1EUD; 1JKJ; 1JLL; 1OI7; 1SCU; 2FP4; 2FPG; 2FPI; 2FPP; 
			
				2NU6; 2NU7; 2NU8; 2NU9; 2NUA; 2SCU; 2YV1; 3MWD; 3MWE; 3PFF; 3UFX; 4XX0; 
				5CAE; 5TDE; 5TDF; 5TDM; 5TDZ; 5TE1; 5TEQ; 5TES; 5TET; 6G4Q; 6HXH; 6O0H; 
				6POE; 6POF; 6QFB; 6UI9; 6UIA; 6UUW; 6UUZ; 6UV5; 6WCV; 6XRU; 7JFP; 7JJ0; 
				7JKR; 7JMK; 7LIW; 7LJ9; 7LLA; 7MSR; 7MSS; 7MST; 7RIG; 7RKZ; 7RMP; 8G1E; 
				8G1F; 8G5C; 8G5D
			
			

			» more