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PROSITE entry PS00408


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General information about the entry

Entry name [info] CONNEXINS_2
Accession [info] PS00408
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00341

Name and characterization of the entry

Description [info] Connexins signature 2.
Pattern [info] 
C-x(3,4)-P-C-x(2,3)-[LIVMTA]-[DENT]-C-[FYN]-[LIVMQ]-[SA]-[KRH]-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 107 in 107 different sequences
Number of true positive hits 107 in 107 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.27 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 4
Site [info] disulfide at position 8
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 107 sequences 

CX32_DANRE  (Q7T047), CX32_MICUN  (P51915), CX33_MICUN  (P51916), 

CXA10_HUMAN (Q969M2), CXA10_MOUSE (Q9WUS4), CXA1_BOVIN  (P18246), 
CXA1_CANLF  (Q6S9C0), CXA1_CHICK  (P14154), CXA1_CHLAE  (Q6TYA9), 
CXA1_DANRE  (O57474), CXA1_ERIEU  (Q6TYA8), CXA1_HUMAN  (P17302), 
CXA1_MACFA  (Q4R4S7), CXA1_MOUSE  (P23242), CXA1_PIG(Q29101), 
CXA1_RABIT  (Q6TYA7), CXA1_RAT(P08050), CXA1_URSAM  (A6XKM2), 
CXA1_XENLA  (P16863), CXA2_XENLA  (P16864), CXA3_BOVIN  (P41987), 
CXA3_CHICK  (P29415), CXA3_HUMAN  (Q9Y6H8), CXA3_MOUSE  (Q64448), 
CXA3_RAT(P29414), CXA3_SHEEP  (Q9TU17), CXA4_BOVIN  (A4IFL1), 
CXA4_HUMAN  (P35212), CXA4_MOUSE  (P28235), CXA4_RAT(Q03190), 
CXA4_XENLA  (P51914), CXA4_XENTR  (Q0V990), CXA5_BOVIN  (Q0VCR2), 
CXA5_CANLF  (P33725), CXA5_CHICK  (P18860), CXA5_HUMAN  (P36382), 
CXA5_MOUSE  (Q01231), CXA5_RAT(P28234), CXA6_MOUSE  (Q6S5G4), 
CXA6_RAT(P28233), CXA8_CHICK  (P36381), CXA8_HUMAN  (P48165), 
CXA8_MOUSE  (P28236), CXA8_RAT(Q8K4Q9), CXA8_SHEEP  (P55917), 
CXA9_HUMAN  (P57773), CXB1_BOVIN  (O18968), CXB1_HORSE  (Q6WGK6), 
CXB1_HUMAN  (P08034), CXB1_MACFA  (Q60HF7), CXB1_MOUSE  (P28230), 
CXB1_RAT(P08033), CXB1_XENLA  (P08983), CXB2_BOVIN  (A2VE67), 
CXB2_GORGO  (Q8MHW5), CXB2_HUMAN  (P29033), CXB2_HYLLA  (Q7JGL3), 
CXB2_MACMU  (Q8MIT8), CXB2_MOUSE  (Q00977), CXB2_PONPY  (Q8MIT9), 
CXB2_RAT(P21994), CXB2_SHEEP  (P46691), CXB3_BOVIN  (Q58D78), 
CXB3_HUMAN  (O75712), CXB3_MOUSE  (P28231), CXB3_RAT(P25305), 
CXB4_HUMAN  (Q9NTQ9), CXB4_MOUSE  (Q02738), CXB4_RAT(P36380), 
CXB5_HUMAN  (O95377), CXB5_MOUSE  (Q02739), CXB5_RAT(P28232), 
CXB6_BOVIN  (Q5E9Z5), CXB6_CHICK  (O93533), CXB6_HUMAN  (O95452), 
CXB6_MOUSE  (P70689), CXB7_HUMAN  (Q6PEY0), CXD2_BOVIN  (Q866T7), 
CXD2_HUMAN  (Q9UKL4), CXD2_LEUER  (P69998), CXD2_LEUOC  (P69999), 
CXD2_MOUSE  (O54851), CXD2_RAT(O70610), CXD3_HUMAN  (Q8N144), 
CXD3_MOUSE  (Q91YD1), CXD4_HUMAN  (Q96KN9), CXD4_MACFA  (Q9N0B3), 
CXD4_MOUSE  (Q8BSD4), CXG1_BOVIN  (Q2HJ66), CXG1_CANLF  (P28228), 
CXG1_CHICK  (P18861), CXG1_CRIGR  (Q6R4A8), CXG1_DANRE  (Q92052), 
CXG1_HUMAN  (P36383), CXG1_MESAU  (Q6PYT3), CXG1_MOUSE  (P28229), 
CXG1_PIG(A4GVD1), CXG1_RAT(A4GG66), CXG1_XENLA  (Q7ZXS7), 
CXG1_XENTR  (Q6NZH5), CXG2_BOVIN  (Q29RK8), CXG2_HUMAN  (Q5T442), 
CXG2_MOUSE  (Q8BQU6), CXG2_RAT(Q80XF7), CXG3_BOVIN  (A3KN25), 
CXG3_HUMAN  (Q8NFK1), CXG3_MOUSE  (Q921C1)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

CXE1_DANRE  (U3JA75), CXE1_HUMAN  (A6NN92), CXE1_MOUSE  (Q9CX92)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			1 sequence
			


			
CXA4_PIG(Q29559)


				
	

	

		PDB
[Detailed view]		
		
			61 PDB
			


			2ZW3; 3IZ1; 3IZ2; 5ER7; 5ERA; 6L3T; 6L3U; 6L3V; 6MHQ; 6MHY; 6UVR; 6UVS; 
			
				6UVT; 7F92; 7F93; 7F94; 7JJP; 7JKC; 7JLW; 7JM9; 7JMC; 7JMD; 7JN0; 7JN1; 
				7QEO; 7QEQ; 7QER; 7QES; 7QET; 7QEU; 7QEV; 7QEW; 7QEY; 7XKI; 7XKK; 7XKT; 
				7XL8; 7XNH; 7XNV; 7XQ9; 7XQB; 7XQD; 7XQF; 7XQG; 7XQH; 7XQI; 7XQJ; 7Z1T; 
				7Z22; 7Z23; 7ZXM; 7ZXN; 7ZXO; 7ZXP; 7ZXQ; 7ZXT; 8GN7; 8GN8; 8GNB; 8HKP; 
				8IYG
			
			

			» more