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PROSITE entry PS00421


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General information about the entry

Entry name [info] TM4_1
Accession [info] PS00421
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00371

Name and characterization of the entry

Description [info] Transmembrane 4 family signature.
Pattern [info]
[GC]-x(3)-[LIVMFS]-x(2)-[GSA]-[LIVMFTC]-[LIVMFA]-G-[CLYI]-x-[GA]-[STAPL]-
x(2)-[EGAR]-x(2)-[CWNLF]-[LIVMGA]-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 101 in 101 different sequences
Number of true positive hits 100 in 100 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 46
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.01 %
Recall (true positives / (true positives + false negatives)) 68.49 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
100 sequences

CD151_CHLAE (P61170), CD151_HUMAN (P48509), CD151_MACMU (P61171), 
CD151_MOUSE (O35566), CD151_RAT   (Q9QZA6), CD37_BOVIN  (Q2KHY8), 
CD37_HUMAN  (P11049), CD37_MOUSE  (Q61470), CD37_RAT(P31053), 
CD53_BOVIN  (Q58DM3), CD53_HUMAN  (P19397), CD53_MOUSE  (Q61451), 
CD53_RAT(P24485), CD63_BOVIN  (Q9XSK2), CD63_FELCA  (Q76B49), 
CD63_HUMAN  (P08962), CD63_MOUSE  (P41731), CD63_RABIT  (Q28709), 
CD63_RAT(P28648), CD81_BOVIN  (Q3ZCD0), CD81_CHLAE  (O97703), 
CD81_HUMAN  (P60033), CD81_MOUSE  (P35762), CD81_PANTR  (P60034), 
CD81_RAT(Q62745), CD81_SAGOE  (Q9N0J9), CD82_HUMAN  (P27701), 
CD82_MOUSE  (P40237), CD82_RAT(O70352), CD9_BOVIN   (P30932), 
CD9_CHLAE   (P30409), CD9_FELCA   (P40239), CD9_HUMAN   (P21926), 
CD9_MOUSE   (P40240), CD9_PIG (Q8WMQ3), CD9_RAT (P40241), 
IM23_SCHHA  (Q26499), IM23_SCHJA  (P27591), IM23_SCHMA  (P19331), 
IM25_SCHJA  (P91799), TET7_ARATH  (Q9SUD4), TET8_ARATH  (Q8S8Q6), 
TSN10_HUMAN (Q9H1Z9), TSN12_BOVIN (Q29RH7), TSN12_CHICK (Q5ZIF5), 
TSN12_HUMAN (O95859), TSN12_MOUSE (Q8BKT6), TSN12_PONAB (Q5R8B5), 
TSN12_RAT   (Q569A2), TSN14_HUMAN (Q8NG11), TSN14_MOUSE (Q8QZY6), 
TSN17_BOVIN (Q58DN3), TSN17_HUMAN (Q96FV3), TSN17_MOUSE (Q9D7W4), 
TSN17_RAT   (Q4V8E0), TSN18_BOVIN (Q58CY8), TSN18_CHICK (A0A8V0ZLT4), 
TSN18_DANRE (A0A8M2B5N2), TSN18_HUMAN (Q96SJ8), TSN18_MOUSE (Q80WR1), 
TSN1_BOVIN  (Q3T0S3), TSN1_HUMAN  (O60635), TSN1_MACFA  (Q4R7W6), 
TSN1_MOUSE  (Q99J59), TSN1_PONAB  (Q5RC27), TSN1_RAT(Q6AYR9), 
TSN2_HUMAN  (O60636), TSN2_MOUSE  (Q922J6), TSN2_RAT(Q9JJW1), 
TSN3_BOVIN  (Q3SZR9), TSN3_HUMAN  (O60637), TSN3_MOUSE  (Q9QY33), 
TSN3_PONAB  (Q5RE11), TSN4_HUMAN  (O14817), TSN4_MOUSE  (Q9DCK3), 
TSN4_PONAB  (Q5RAP3), TSN5_BOVIN  (Q17QJ5), TSN5_HUMAN  (P62079), 
TSN5_MOUSE  (P62080), TSN5_RAT(Q68VK5), TSN6_BOVIN  (Q32KU6), 
TSN6_HUMAN  (O43657), TSN6_PONAB  (Q5RAS5), TSN7_HUMAN  (P41732), 
TSN7_MOUSE  (Q62283), TSN7_PANTR  (Q7YQL0), TSN7_PONPY  (Q7YQK9), 
TSN8_BOVIN  (Q2KIS9), TSN8_HUMAN  (P19075), TSN8_MOUSE  (Q8R3G9), 
TSN8_PONAB  (Q5R9S6), TSN9_DANRE  (Q6GMK6), TSN9_HUMAN  (O75954), 
TSN9_MOUSE  (Q8BJU2), TSN9_PIG(Q06AA5), TSN9_SALSA  (B5X3I6), 
TSN9_SHEEP  (B3VSC2), TSN9_XENLA  (Q6DCQ3), TSN9_XENTR  (B0BM39), 
TSP17_CAEEL (Q11098)
» more

UniProtKB/Swiss-Prot
False negative sequences
46 sequences

CD151_BOVIN (Q3ZBH3), TET10_ARATH (F4I214), TET11_ARATH (Q9LPR6), 
TET12_ARATH (Q9FN51), TET13_ARATH (Q9SI56), TET14_ARATH (Q58G33), 
TET15_ARATH (Q1PDI1), TET16_ARATH (Q5BQ04), TET17_ARATH (Q58G35), 
TET18_ARATH (Q93XY5), TET19_ARATH (Q940P5), TET20_ARATH (Q9SVU4), 
TET2_ARATH  (Q9ZUN5), TET3_ARATH  (Q9M1E7), TET4_ARATH  (Q9LSS4), 
TET5_ARATH  (Q84WF6), TET6_ARATH  (Q9C7C1), TET9_ARATH  (Q9M0B7), 
TRN2_ARATH  (Q9FIQ5), TS31A_XENLA (Q5XHG6), TS31B_XENLA (Q7ZWW7), 
TSN10_MOUSE (Q8VCF5), TSN11_BOVIN (Q0VC33), TSN11_HUMAN (A1L157), 
TSN11_MOUSE (Q9D1D1), TSN11_RAT   (Q568Y5), TSN13_BOVIN (Q3ZBV0), 
TSN13_HUMAN (O95857), TSN13_MOUSE (Q9D8C2), TSN13_RAT   (Q5FVL6), 
TSN15_BOVIN (Q1JQA4), TSN15_HUMAN (O95858), TSN15_MOUSE (F7BWT7), 
TSN16_HUMAN (Q9UKR8), TSN31_BOVIN (Q32KP1), TSN31_DANRE (Q7ZUB3), 
TSN31_HUMAN (Q12999), TSN31_MOUSE (Q9CQ88), TSN31_PIG   (Q29257), 
TSN31_PONAB (Q5RAP8), TSN31_RAT   (Q5U1V9), TSN36_DANRE (Q6NWG0), 
TSN6_MOUSE  (O70401), TSP12_CAEEL (Q22495), TSP14_CAEEL (H2L006), 
TSP1_CAEEL  (P34285)
» more

UniProtKB/Swiss-Prot
False positive sequences
1 sequence

NRTP_PICP2  (B1XLL7)

		
PDB
[Detailed view]
3 PDB

5TCX; 6K4J; 7JIC