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PROSITE entry PS00441


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00441
Entry name [info] CHALCONE_SYNTH
Accession [info] PS00441
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00403
Associated ProRule [info] PRU10023

Name and characterization of the entry

Description [info] Chalcone and stilbene synthases active site.
Pattern [info] 
R-[LIVMFYS]-x-[LIVM]-x-[QHG]-x-G-C-[FYNA]-[GAPV]-G-[GAC]-[STAVK]-x-
[LIVMF]-[RAL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 162 in 162 different sequences
Number of true positive hits 162 in 162 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 25
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.63 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 162 sequences 

2PS_GERHY   (P48391), ACS2_RUTGR  (Q9FSC0), ACS3_RUTGR  (Q9FSC2), 

ACS4_RUTGR  (Q9FSC1), BBS_PHASS   (P53416), BCSA_BACSU  (P54157), 
CHS1_CAMSI  (P48386), CHS1_CASGL  (Q9ZRR8), CHS1_CICAR  (Q9SML4), 
CHS1_CITSI  (Q9XJ58), CHS1_DAUCA  (Q9ZS41), CHS1_GERHY  (P48390), 
CHS1_HORVU  (P26018), CHS1_IPOBA  (Q9MB33), CHS1_MAIZE  (P24824), 
CHS1_MEDSA  (P30073), CHS1_ORYSI  (A2ZEX7), CHS1_ORYSJ  (Q2R3A1), 
CHS1_PEA(Q01286), CHS1_RUTGR  (Q9FSB9), CHS1_SECCE  (P53414), 
CHS1_SINAL  (P13416), CHS1_SOLLC  (P23418), CHS1_SORBI  (Q9XGX2), 
CHS1_SOYBN  (P24826), CHS1_TRISU  (P51083), CHS2_CAMSI  (P48387), 
CHS2_CITSI  (Q9XJ57), CHS2_DAUCA  (Q9ZS40), CHS2_HORVU  (Q96562), 
CHS2_IPOBA  (Q9MB41), CHS2_MAIZE  (P24825), CHS2_MEDSA  (P30074), 
CHS2_ORYSJ  (Q8H4L3), CHS2_PEA(Q01287), CHS2_RUTGR  (Q9FSB8), 
CHS2_SECCE  (P53415), CHS2_SOLLC  (P23419), CHS2_SOLTU  (Q43188), 
CHS2_SORBI  (Q9SBL7), CHS2_SOYBN  (P17957), CHS2_TRISU  (P51084), 
CHS3_BROFI  (O23729), CHS3_CAMSI  (P48388), CHS3_GERHY  (P48392), 
CHS3_IPOBA  (Q9MB40), CHS3_MEDSA  (P51077), CHS3_PEA(O23883), 
CHS3_RUTGR  (Q9FSB7), CHS3_SINAL  (P13417), CHS3_SORBI  (Q9SBL6), 
CHS3_SOYBN  (P19168), CHS3_TRISU  (P51085), CHS4_BROFI  (O23730), 
CHS4_IPOBA  (Q9MB39), CHS4_MEDSA  (P30075), CHS4_PEA(O23882), 
CHS4_SORBI  (Q9SBL5), CHS4_TRISU  (P51086), CHS5_MEDSA  (P51078), 
CHS5_PEA(O23884), CHS5_SORBI  (Q9SBL4), CHS5_SOYBN  (P48406), 
CHS5_TRISU  (P51087), CHS6_IPOBA  (Q9MB38), CHS6_MEDSA  (P51079), 
CHS6_PEA(Q01288), CHS6_SORBI  (Q9SBL3), CHS6_SOYBN  (P30080), 
CHS6_TRISU  (P51088), CHS7_IPOBA  (Q9MB37), CHS7_MEDSA  (P51080), 
CHS7_PICMA  (Q9M5M0), CHS7_SORBI  (Q9XGX1), CHS7_SOYBN  (P30081), 
CHS8_BROFI  (O23731), CHS8_IPOBA  (Q9MB36), CHS8_MEDSA  (P30076), 
CHS9_DAUCA  (Q9SB26), CHS9_MEDSA  (P30077), CHSA_IPOCO  (P48393), 
CHSA_IPONI  (P48395), CHSA_IPOPL  (P48400), CHSA_IPOPU  (P48397), 
CHSA_IPOTF  (P48401), CHSA_IPOTR  (P48403), CHSA_PEA(P51081), 
CHSA_PETHY  (P08894), CHSA_SOLTU  (Q41436), CHSB_IPOCO  (P48394), 
CHSB_IPONI  (P48396), CHSB_IPOPU  (P48398), CHSB_IPOTF  (P48402), 
CHSB_IPOTR  (P48404), CHSB_PEA(P51082), CHSB_PETHY  (P22924), 
CHSB_SOLTU  (Q43163), CHSC_IPOPU  (P48399), CHSD_IPONI  (O22045), 
CHSD_PETHY  (P22925), CHSE_IPONI  (O22046), CHSE_IPOPU  (O22047), 
CHSF_PETHY  (P22926), CHSG_PETHY  (P22927), CHSH1_HUMLU (Q9FEY5), 
CHSH2_HUMLU (A0AMG7), CHSH3_HUMLU (A0AMG8), CHSH4_HUMLU (A0AMG9), 
CHSJ_PETHY  (P22928), CHSY_ANTMA  (P06515), CHSY_ARAAL  (Q9SEP4), 
CHSY_ARATH  (P13114), CHSY_BETPN  (P51075), CHSY_CALCH  (P48385), 
CHSY_CARAN  (Q9SEP2), CHSY_CATRO  (Q9ZRS4), CHSY_CHRAE  (O04220), 
CHSY_DIACA  (P48389), CHSY_DIAMO  (Q9LKP7), CHSY_EQUAR  (Q9MBB1), 
CHSY_HYDMC  (O82144), CHSY_HYPAN  (Q9FUB7), CHSY_MATIN  (P17818), 
CHSY_ONOVI  (O22586), CHSY_PERAE  (Q9ZU06), CHSY_PERFR  (O04111), 
CHSY_PETCR  (P16107), CHSY_PHAVU  (P49440), CHSY_PINST  (O65872), 
CHSY_PINSY  (P30079), CHSY_PUEML  (P23569), CHSY_RAPSA  (O22652), 
CHSY_VIGUN  (P51089), CHSY_VITVI  (P51090), CHS_CANSA   (Q8RVK9), 
CHS_RHODA   (A0A2Z5QL08), DPS1_PINST  (P48407), DPS2_PINST  (P48408), 
DPSS_PINSY  (Q02323), OLIS_CANSA  (B1Q2B6), ORS_RHODA   (A0A2Z5QKZ7), 
PKS1_RUBID  (Q9AU11), PKS2_RUBID  (Q9AU10), PKS3_RUBID  (Q9AU09), 
PKS4_RUBID  (B0LDU5), PKS5_RUBID  (B0LDU6), PKSF3_CANSA (F1LKH5), 
PKSG1_CANSA (F1LKH6), PKSG2_CANSA (F1LKH7), PKSG4_CANSA (F1LKH8), 
PKSG5_CANSA (F1LKH9), THS1_ARAHY  (P20178), THS1_VITVI  (P28343), 
THS2_ARAHY  (P20077), THS2_VITVI  (P51070), THS3_ARAHY  (P51069), 
THS3_VITVI  (P51071), THS4_VITVI  (A5AEM3), THS5_VITVI  (A5C9M2), 
THS7_VITVI  (A2ICC6), VPS_HUMLU   (O80400), VPS_PSINU   (Q9SLX9)
» more

UniProtKB/Swiss-Prot
False negative sequences		 25 sequences 

BAS_RHEPA   (Q94FV7), CURS1_CURLO (C0SVZ6), CURS2_CURLO (C6L7V8), 

CURS3_CURLO (C6L7V9), CUS_ORYSJ   (Q8LIL0), DCS_CURLO   (C0SVZ5), 
DPGA_AMYBA  (Q939X3), DPGA_AMYOR  (G4V4T4), DPGA_STRTO  (Q8KLK5), 
OKS_ALOAR   (Q3L7F5), PCS_ALOAR   (Q58VP7), PHLD_PSEF5  (Q4K418), 
PHLD_PSEFL  (Q51725), PKS10_MYCTO (P9WPF4), PKS10_MYCTU (P9WPF5), 
PKS1_DICDI  (Q55E72), PKS3_ALOAR  (C4MBZ5), PKS4_ALOAR  (C4NF90), 
PKS5_ALOAR  (C4NF91), PKSA_ARATH  (O23674), PKSB_ARATH  (Q8LDM2), 
RPPA_STRC0  (B0FYK7), RPPA_STRCO  (Q9FCA7), RPPA_STRGR  (Q54240), 
STLB_DICDI  (Q54FI3)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

CHSY_FRAAN  (P51076), CHSY_MALDO  (P30078)


				
	

	

		PDB
[Detailed view]		
		
			31 PDB
			


			1BI5; 1BQ6; 1CGK; 1CGZ; 1D6H; 1D6I; 1EE0; 1I86; 1I88; 1I89; 1I8B; 1JWX; 
			
				1QLV; 1U0U; 1U0V; 1U0W; 1XES; 1XET; 4YJY; 6DX9; 6DXA; 6DXB; 6DXD; 6GW3; 
				7BUR; 7BUS; 7W6G; 8B32; 8B35; 8B3C; 8JRD
			
			

			» more