PROSITE entry PS00444

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General information about the entry

Entry name [info]	POLYPRENYL_SYNTHASE_2
Accession [info]	PS00444
Entry type [info]	PATTERN
Date [info]	01-MAY-1991 CREATED; 01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00407

Name and characterization of the entry

Description [info]	Polyprenyl synthases signature 2.
Pattern [info]	[LIVMFY]-G-x(2)-[FYL]-Q-[LIVM]-x-D-D-[LIVMFY]-x-[DNG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.

Total number of hits	172 in 172 different sequences
Number of true positive hits	172 in 172 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	12
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	93.48 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

172 sequences

ABVS_ASPBC  (A0A1L9UKS1), ASTC_TALWO  (A0A3Q9FFM1), ATMG_ASPFL  (Q672V6),

AUAS_ASPUT  (P9WEP0), BSC8_ALTBR  (C9K2Q3), BTCA_COLOR  (N4V6D4), 
BTCA_NEOBT  (A0A2Z6FZ31), CGDS_COLGL  (P9WEV7), COQ1_NEUCR  (Q7S565), 
COQ1_YARLI  (Q6CBH3), COQ1_YEAST  (P18900), CRTE_CERS4  (P54976), 
CRTE_CYAPA  (P48368), CRTE_PANAN  (P21684), CRTE_PICP2  (B1XJV9), 
CRTE_PSEVU  (P22873), CRTE_RHOCB  (P17060), DPASD_APISA (P9WEX3), 
DPCHD_COLHI (H1VQB1), DPFGD_GIBZE (I1RL14), DPMAD_METAN (P9WEX9), 
DPMPD_MACPH (P9WEW8), DPS1_DICDI  (Q54VJ9), DPS1_HUMAN  (Q5T2R2), 
DPS1_MOUSE  (Q33DR2), DPS1_SCHPO  (O43091), ERG20_ASPFU (Q4WEB8), 
ERG20_CANAL (A0A1D8PH78), ERG20_GANLU (B4YA15), ERG20_GIBZE (V6RG22), 
ERG20_SCHPO (O14230), ERG20_YEAST (P08524), ERIE_HERER  (A0A1V0QSA8), 
EVVS_EMEVA  (A0A0P0ZD79), FC1_PHOAM   (A2PZA5), FOFS_FUSOX  (P9WER6), 
FPPS1_ARATH (Q09152), FPPS1_ARTSI (Q7XYS9), FPPS1_LUPAL (P49351), 
FPPS1_PARAR (O24241), FPPS2_ARATH (Q43315), FPPS2_ARTSI (Q7XYT0), 
FPPS2_LUPAL (P49352), FPPS2_PARAR (O24242), FPPS_ARTAN  (P49350), 
FPPS_BOVIN  (Q8WMY2), FPPS_CHICK  (P08836), FPPS_GIBFU  (Q92235), 
FPPS_HELAN  (O64905), FPPS_HUMAN  (P14324), FPPS_KLULA  (P49349), 
FPPS_MAIZE  (P49353), FPPS_MOUSE  (Q920E5), FPPS_MURHI  (A0A343W970), 
FPPS_MYCBO  (P0A5H9), FPPS_MYCTO  (P9WKH0), FPPS_MYCTU  (P9WKH1), 
FPPS_NEUCR  (Q92250), FPPS_NEZVI  (A0A386JVA3), FPPS_RAT(P05369), 
FPS_DICDI   (Q9NH03), FPS_PANGI   (Q4JHN6), FUP1_FUSPR  (A0A1L7VFX3), 
GA5_GIBF5   (S0E627), GFPPS_MYCTU (O53507), GFPS_NATPD  (Q3IPL1), 
GGDPS_MELLI (A0A858E6N7), GGDPS_MELLP (A0A858E7G0), GGPP1_ARATH (P34802), 
GGPP2_ARATH (O04046), GGPP3_ARATH (Q9LUD9), GGPP4_ARATH (Q9SLG2), 
GGPP6_ARATH (O22043), GGPP7_ARATH (Q9ZU77), GGPP8_ARATH (Q9LRR0), 
GGPP9_ARATH (Q9LUE1), GGPPA_ARATH (Q9LJY2), GGPPB_ARATH (Q9LIA0), 
GGPPC_ARATH (Q9LHR4), GGPPS_BOVIN (P56966), GGPPS_CAPAN (P80042), 
GGPPS_CATRO (Q42698), GGPPS_DICDI (Q54BK1), GGPPS_EREGS (Q758K0), 
GGPPS_GIBFU (Q92236), GGPPS_HEVBR (Q94ID7), GGPPS_HUMAN (O95749), 
GGPPS_MOUSE (Q9WTN0), GGPPS_MUCCL (Q9P885), GGPPS_NEUCR (P24322), 
GGPPS_RAT   (Q6F596), GGPPS_SCHPO (O59703), GGPPS_SINAL (Q43133), 
GGPPS_YEAST (Q12051), GGPP_METMA  (Q8PW34), GGPS_SACS2  (P95999), 
GGPS_SULAC  (P39464), GGS1_HYPPI  (A0A2I6PJ05), GGS1_PHOAM  (B2DBE8), 
GGS2_ZYMTI  (F9WWF1), GGS3_ZYMTI  (F9XLC1), GGS4_PHOAM  (B2DBE9), 
GGS_NEOBT   (Q6F5E6), GSS1_ZYMTI  (F9WZD2), HEPS2_BACSU (P31114), 
HEPS2_GEOSE (P55785), HEXB_MICLU  (O66129), HEXPP_SACS2 (Q97W92), 
IDSA_METJA  (Q58270), IDSA_METTH  (O26156), IDSA_METTM  (Q53479), 
IDTG_CLAPA  (J7FIX8), ISPA_AQUAE  (O66952), ISPA_BACSU  (P54383), 
ISPA_BRADU  (Q45220), ISPA_BUCAI  (P57537), ISPA_BUCAP  (Q8K9A0), 
ISPA_ECOLI  (P22939), ISPA_GEOSE  (Q08291), ISPA_HAEIN  (P45204), 
ISPA_MICLU  (O66126), ISPA_SINFN  (P55539), ISPB_ECOLI  (P0AD57), 
ISPB_HAEIN  (P44916), ISPB_SHIFL  (P0AD58), JANG_PENJA  (A0A0E3D8M9), 
LTMG_EPIFF  (Q56RZ3), LTMG_EPIFI  (Q56RZ7), NFSS_NEOFI  (A1DN30), 
NPPPS_MYCTU (O06428), OBLA_ASPCI  (A0A0U5G0B1), OBLA_ASPCL  (A1C8C3), 
OBLA_COCH5  (M2V8C1), OBLA_EMEVA  (A0A1V1FVQ6), OLCC_PENCN  (P9WEQ2), 
PAPS_PHOAM  (P9WEV6), PAXG_PENPX  (Q9C446), PBCB_EMENI  (A0A1U8QLG8), 
PCCS_PENCH  (A0A348DU52), PCHDS_PENRW (B6HFX8), PENG_PENCR  (A0A0E3D8P4), 
PLE4_CLIPA  (A0A2L0VXR5), PLE4_RHOPP  (A0A6S6QJ62), PRDS_PENRF  (W6QAE7), 
PREA_CYACA  (Q9TLS1), PREA_CYAPA  (P31171), PREA_NEOYE  (Q1XDL8), 
PREA_PORPU  (P51268), PREA_SYNY3  (P72580), PTMG_PENSI  (A0A140JWS2), 
PVCPS_TALVE (A0A348FUE1), PVPS_TALVE  (A0A2Z6AQX6), QNN1_EMEVA  (A0A1Y1C7Q5), 
SDNC_SORAA  (A0A1B4XBK0), SDSA_RHOCA  (O24743), SPS1_ARATH  (Q8S948), 
SPS1_ORYSJ  (Q653T6), SPS2_ARATH  (Q76FS5), SPS2_ORYSJ  (Q75HZ9), 
SPS3_ARATH  (Q5HZ00), SPS3_ORYSJ  (Q0INZ4), SUBD_METRA  (E9F5E9), 
TPCA_COCH5  (M2U578), TPRT_ASFB7  (Q65164), TPRT_ASFK5  (P0C9E2), 
TPRT_ASFM2  (Q8V9T7), TPRT_ASFP4  (P0C9E0), TPRT_ASFWA  (P0C9E1), 
TPS_MATON   (A0A7D0AGU9), TVTS_TALVE  (P9WER5), VRTD_PENAE  (D7PHZ5), 
Y8823_DICDI (Q54XP1)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

12 sequences

COMQ_BACIU  (P0DV08), COMQ_BACNB  (D4G0R4), COMQ_BACSC  (P0DV09),

COMQ_BACSU  (P33690), DLP1_HUMAN  (Q86YH6), DLP1_MOUSE  (Q33DR3), 
DLP1_RAT(Q5U2R1), DLP1_SCHPO  (O13851), GGPPS_GEOAI (A0A0A7GEY4), 
GGPPS_MYCTU (O50410), GPPS_IPSPI  (Q58GE8), GPPS_MYCTU  (O05572)

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PDB
[Detailed view]

150 PDB

1FPS; 1RQI; 1RQJ; 1UBV; 1UBW; 1UBX; 1UBY; 1YQ7; 1YV5; 1ZW5; 2AZJ; 2AZK; 2DH4; 2E8T; 2E8U; 2E8V; 2E8W; 2E8X; 2E90; 2E91; 2E92; 2E93; 2E94; 2E95; 2F7M; 2F89; 2F8C; 2F8Z; 2F92; 2F94; 2F9K; 2J1O; 2J1P; 2OPM; 2OPN; 2Q80; 2QIS; 2RAH; 2VF6; 2Z4V; 2Z4W; 2Z4X; 2Z4Y; 2Z4Z; 2Z50; 2Z52; 2Z78; 2Z7H; 2Z7I; 2ZEU; 2ZEV; 3APZ; 3AQ0; 3AQB; 3AQC; 3B7L; 3CP6; 3N1V; 3N1W; 3N3L; 3N45; 3N46; 3N49; 3N5H; 3N5J; 3N6K; 3RYE; 3S4J; 4DEM; 4GA3; 4H5C; 4H5D; 4H5E; 4JVJ; 4KFA; 4KK2; 4KPD; 4KPJ; 4KQ5; 4KQS; 4KQU; 4L2X; 4LFV; 4LPG; 4LPH; 4N1Z; 4N9U; 4NFI; 4NFJ; 4NFK; 4NG6; 4P0V; 4P0W; 4P0X; 4PVX; 4PVY; 4Q23; 4QPF; 4QXS; 4RXA; 4XQR; 4XQS; 4XQT; 5AYP; 5CG5; 5CG6; 5DGM; 5DGN; 5DGS; 5DIQ; 5DJP; 5DJR; 5DJV; 5E8H; 5E8K; 5E8L; 5ERN; 5ERO; 5JA0; 5JUZ; 5JV0; 5JV1; 5JV2; 5KSX; 5YGI; 5ZE6; 5ZLF; 6C56; 6C57; 6N7Y; 6N7Z; 6N82; 6N83; 6OAG; 6OAH; 6R4V; 6SXL; 6SXN; 6V0K; 7JTH; 7S09; 7S0A; 7S0H; 7S0L; 7S0M; 8EAX; 8F8F; 8F8K; 8F8L; 8HDL
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