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PROSITE entry PS00447


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PURL: https://purl.expasy.org/prosite/signature/PS00447

Direct ScanProsite submission
General information about the entry

Entry name [info] DNA_POLYMERASE_A
Accession [info] PS00447
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00412

Name and characterization of the entry

Description [info] DNA polymerase family A signature.
Pattern [info] 
R-x(2)-[GSAV]-K-x(3)-[LIVMFY]-[AGQ]-x(2)-Y-x(2)-[GS]-x(3)-[LIVMA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 58 in 58 different sequences
Number of true positive hits 56 in 56 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 96.55 %
Recall (true positives / (true positives + false negatives)) 84.85 %

Comments [info]

Taxonomic range [info] Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 56 sequences 

DPM1_ARATH  (Q9LM93), DPO1F_THETH (P30313), DPO1T_THET8 (P52028), 

DPO1_AQUAE  (O67779), DPO1_BACCA  (Q04957), DPO1_BACSU  (O34996), 
DPO1_BORBU  (O51498), DPO1_CALBD  (Q59156), DPO1_CHLAA  (O08307), 
DPO1_DEIRA  (P52027), DPO1_ECOLI  (P00582), DPO1_GEOSE  (P52026), 
DPO1_HAEIN  (P43741), DPO1_HELPJ  (Q9ZJE9), DPO1_HELPY  (P56105), 
DPO1_LACLA  (Q9CDS1), DPO1_LACLM  (O32801), DPO1_MYCBO  (P0A551), 
DPO1_MYCLE  (P46835), DPO1_MYCTO  (P9WNU4), DPO1_MYCTU  (P9WNU5), 
DPO1_PSEAE  (Q9HT80), DPO1_RHILE  (Q9S1G2), DPO1_RICBR  (Q1RH76), 
DPO1_RICCN  (Q92GB7), DPO1_RICFE  (Q9RAA9), DPO1_RICHE  (Q9RLB6), 
DPO1_RICPR  (O05949), DPO1_RICTY  (Q9RLA0), DPO1_SALTY  (Q9F173), 
DPO1_STRPN  (P59199), DPO1_STRR6  (P59200), DPO1_THEAQ  (P19821), 
DPO1_THECA  (P80194), DPO1_THEFI  (O52225), DPO1_TREPA  (P74933), 
DPOG1_CHICK (Q92076), DPOG1_DROME (Q27607), DPOG1_HUMAN (P54098), 
DPOG1_MOUSE (P54099), DPOG1_RAT   (Q9QYV8), DPOG1_XENLA (Q91684), 
DPOG_NEUCR  (Q9Y767), DPOG_YEAST  (P15801), DPOLA_BPPM6 (P0DTK4), 
DPOLQ_CAEEL (A0FLQ6), DPOLQ_HUMAN (O75417), DPOLQ_MOUSE (Q8CGS6), 
DPOL_BPE32  (B0FIL5), DPOL_BPMD2  (O64235), DPOL_BPML5  (Q05254), 
DPOL_BPSP1  (P30314), DPOL_BPSP2  (P06225), DPOL_BPT3   (P20311), 
DPOL_BPT5   (P19822), DPOL_BPT7   (P00581)
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

DPO1_SYNY3  (Q55971), DPOG_PICPA  (Q01941), DPOG_SCHPO  (Q12704), 

DPOLN_HUMAN (Q7Z5Q5), DPOLN_MOUSE (Q7TQ07), DPOLQ_DROME (O18475), 
POLIA_ARATH (F4I6M1), POLIA_ORYSJ (Q6Z4T5), POLIB_ARATH (Q84ND9), 
POLIB_ORYSJ (Q6Z4T3)
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

AGGC_ECOLX  (P46005), FA83B_MOUSE (Q0VBM2)


				
	

	

		PDB
[Detailed view]		
		
			190 PDB
			


			pdb_00001bgx; pdb_00001d8y; pdb_00001d9d; pdb_00001d9f; pdb_00001dpi; pdb_00001jxe; pdb_00001kfd; pdb_00001kfs; pdb_00001kln; pdb_00001krp; pdb_00001ksp; pdb_00001ktq; 
			
				pdb_00001l3s; pdb_00001l3t; pdb_00001l3u; pdb_00001l3v; pdb_00001l5u; pdb_00001lv5; pdb_00001njx; pdb_00001njy; pdb_00001njz; pdb_00001nk0; pdb_00001nk4; pdb_00001nk5; 
				pdb_00001nk6; pdb_00001nk7; pdb_00001nk8; pdb_00001nk9; pdb_00001nkb; pdb_00001nkc; pdb_00001nke; pdb_00001qsl; pdb_00001qss; pdb_00001qsy; pdb_00001qtm; pdb_00001skr; 
				pdb_00001sks; pdb_00001skw; pdb_00001sl0; pdb_00001sl1; pdb_00001sl2; pdb_00001t7p; pdb_00001t8e; pdb_00001taq; pdb_00001tau; pdb_00001tk0; pdb_00001tk5; pdb_00001tk8; 
				pdb_00001tkd; pdb_00001u45; pdb_00001u47; pdb_00001u48; pdb_00001u49; pdb_00001u4b; pdb_00001ua1; pdb_00001x9m; pdb_00001x9s; pdb_00001x9w; pdb_00001xc9; pdb_00001xwl; 
				pdb_00001zyq; pdb_00002ajq; pdb_00002bdp; pdb_00002hhx; pdb_00002kfn; pdb_00002kfz; pdb_00002ktq; pdb_00002kzm; pdb_00002kzz; pdb_00003bdp; pdb_00003eyz; pdb_00003ez5; 
				pdb_00003ikm; pdb_00003ktq; pdb_00003lwl; pdb_00003lwm; pdb_00003m8r; pdb_00003m8s; pdb_00003ojs; pdb_00003oju; pdb_00003po4; pdb_00003po5; pdb_00003py8; pdb_00003rr7; 
				pdb_00003rr8; pdb_00003rrg; pdb_00003rrh; pdb_00003rtv; pdb_00003sv3; pdb_00003sv4; pdb_00003syz; pdb_00003sz2; pdb_00003t3f; pdb_00004bdp; pdb_00004bwj; pdb_00004bwm; 
				pdb_00004c8k; pdb_00004c8l; pdb_00004c8m; pdb_00004c8n; pdb_00004c8o; pdb_00004cch; pdb_00004df4; pdb_00004df8; pdb_00004dfj; pdb_00004dfk; pdb_00004dfm; pdb_00004dfp; 
				pdb_00004dle; pdb_00004dlg; pdb_00004elt; pdb_00004elu; pdb_00004elv; pdb_00004ktq; pdb_00004n56; pdb_00004n5s; pdb_00004x0p; pdb_00004x0q; pdb_00004xiu; pdb_00004ztu; 
				pdb_00004ztz; pdb_00005c51; pdb_00005c52; pdb_00005c53; pdb_00005e41; pdb_00005ikn; pdb_00005ktq; pdb_00005nkl; pdb_00005o7t; pdb_00005oxj; pdb_00005szt; pdb_00005w6k; 
				pdb_00005w6q; pdb_00005ytc; pdb_00005ytd; pdb_00005yte; pdb_00005ytf; pdb_00005ytg; pdb_00005yth; pdb_00005z3n; pdb_00006fbc; pdb_00006fbd; pdb_00006fbe; pdb_00006fbf; 
				pdb_00006fbg; pdb_00006fbh; pdb_00006fbi; pdb_00006n7w; pdb_00006n9u; pdb_00006n9v; pdb_00006n9w; pdb_00006n9x; pdb_00006p7e; pdb_00006q4u; pdb_00006q4v; pdb_00006xbu; 
				pdb_00007owf; pdb_00007zus; pdb_00007zx0; pdb_00007zx1; pdb_00008d33; pdb_00008d37; pdb_00008d3r; pdb_00008d42; pdb_00008e23; pdb_00008e24; pdb_00008g5i; pdb_00008g5j; 
				pdb_00008g5k; pdb_00008g5l; pdb_00008g5m; pdb_00008g5n; pdb_00008g5o; pdb_00008g5p; pdb_00008gd7; pdb_00008oo6; pdb_00008ooy; pdb_00008t7e; pdb_00008udk; pdb_00008udl; 
				pdb_00008v54; pdb_00008v55; pdb_00008v5d; pdb_00008v5r; pdb_00008xjr; pdb_00008xk9; pdb_00009au8; pdb_00009au9; pdb_00009fm3; pdb_00009fmf
			
			

			» more