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PROSITE entry PS00447


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00447
Entry name [info] DNA_POLYMERASE_A
Accession [info] PS00447
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00412

Name and characterization of the entry

Description [info] DNA polymerase family A signature.
Pattern [info] 
R-x(2)-[GSAV]-K-x(3)-[LIVMFY]-[AGQ]-x(2)-Y-x(2)-[GS]-x(3)-[LIVMA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 58 in 58 different sequences
Number of true positive hits 56 in 56 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 96.55 %
Recall (true positives / (true positives + false negatives)) 84.85 %

Comments [info]

Taxonomic range [info] Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 56 sequences 

DPM1_ARATH  (Q9LM93), DPO1F_THETH (P30313), DPO1T_THET8 (P52028), 

DPO1_AQUAE  (O67779), DPO1_BACCA  (Q04957), DPO1_BACSU  (O34996), 
DPO1_BORBU  (O51498), DPO1_CALBD  (Q59156), DPO1_CHLAA  (O08307), 
DPO1_DEIRA  (P52027), DPO1_ECOLI  (P00582), DPO1_GEOSE  (P52026), 
DPO1_HAEIN  (P43741), DPO1_HELPJ  (Q9ZJE9), DPO1_HELPY  (P56105), 
DPO1_LACLA  (Q9CDS1), DPO1_LACLM  (O32801), DPO1_MYCBO  (P0A551), 
DPO1_MYCLE  (P46835), DPO1_MYCTO  (P9WNU4), DPO1_MYCTU  (P9WNU5), 
DPO1_PSEAE  (Q9HT80), DPO1_RHILE  (Q9S1G2), DPO1_RICBR  (Q1RH76), 
DPO1_RICCN  (Q92GB7), DPO1_RICFE  (Q9RAA9), DPO1_RICHE  (Q9RLB6), 
DPO1_RICPR  (O05949), DPO1_RICTY  (Q9RLA0), DPO1_SALTY  (Q9F173), 
DPO1_STRPN  (P59199), DPO1_STRR6  (P59200), DPO1_THEAQ  (P19821), 
DPO1_THECA  (P80194), DPO1_THEFI  (O52225), DPO1_TREPA  (P74933), 
DPOG1_CHICK (Q92076), DPOG1_DROME (Q27607), DPOG1_HUMAN (P54098), 
DPOG1_MOUSE (P54099), DPOG1_RAT   (Q9QYV8), DPOG1_XENLA (Q91684), 
DPOG_NEUCR  (Q9Y767), DPOG_YEAST  (P15801), DPOLA_BPPM6 (P0DTK4), 
DPOLQ_CAEEL (A0FLQ6), DPOLQ_HUMAN (O75417), DPOLQ_MOUSE (Q8CGS6), 
DPOL_BPE32  (B0FIL5), DPOL_BPMD2  (O64235), DPOL_BPML5  (Q05254), 
DPOL_BPSP1  (P30314), DPOL_BPSP2  (P06225), DPOL_BPT3   (P20311), 
DPOL_BPT5   (P19822), DPOL_BPT7   (P00581)
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

DPO1_SYNY3  (Q55971), DPOG_PICPA  (Q01941), DPOG_SCHPO  (Q12704), 

DPOLN_HUMAN (Q7Z5Q5), DPOLN_MOUSE (Q7TQ07), DPOLQ_DROME (O18475), 
POLIA_ARATH (F4I6M1), POLIA_ORYSJ (Q6Z4T5), POLIB_ARATH (Q84ND9), 
POLIB_ORYSJ (Q6Z4T3)
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

AGGC_ECOLX  (P46005), FA83B_MOUSE (Q0VBM2)


				
	

	

		PDB
[Detailed view]		
		
			188 PDB
			


			1BGX; 1D8Y; 1D9D; 1D9F; 1DPI; 1JXE; 1KFD; 1KFS; 1KLN; 1KRP; 1KSP; 1KTQ; 
			
				1L3S; 1L3T; 1L3U; 1L3V; 1L5U; 1LV5; 1NJX; 1NJY; 1NJZ; 1NK0; 1NK4; 1NK5; 
				1NK6; 1NK7; 1NK8; 1NK9; 1NKB; 1NKC; 1NKE; 1QSL; 1QSS; 1QSY; 1QTM; 1SKR; 
				1SKS; 1SKW; 1SL0; 1SL1; 1SL2; 1T7P; 1T8E; 1TAQ; 1TAU; 1TK0; 1TK5; 1TK8; 
				1TKD; 1U45; 1U47; 1U48; 1U49; 1U4B; 1UA1; 1X9M; 1X9S; 1X9W; 1XC9; 1XWL; 
				1ZYQ; 2AJQ; 2BDP; 2HHX; 2KFN; 2KFZ; 2KTQ; 2KZM; 2KZZ; 3BDP; 3EYZ; 3EZ5; 
				3IKM; 3KTQ; 3LWL; 3LWM; 3M8R; 3M8S; 3OJS; 3OJU; 3PO4; 3PO5; 3PY8; 3RR7; 
				3RR8; 3RRG; 3RRH; 3RTV; 3SV3; 3SV4; 3SYZ; 3SZ2; 3T3F; 4BDP; 4BWJ; 4BWM; 
				4C8K; 4C8L; 4C8M; 4C8N; 4C8O; 4CCH; 4DF4; 4DF8; 4DFJ; 4DFK; 4DFM; 4DFP; 
				4DLE; 4DLG; 4ELT; 4ELU; 4ELV; 4KTQ; 4N56; 4N5S; 4X0P; 4X0Q; 4XIU; 4ZTU; 
				4ZTZ; 5C51; 5C52; 5C53; 5E41; 5IKN; 5KTQ; 5NKL; 5O7T; 5OXJ; 5SZT; 5W6K; 
				5W6Q; 5YTC; 5YTD; 5YTE; 5YTF; 5YTG; 5YTH; 5Z3N; 6FBC; 6FBD; 6FBE; 6FBF; 
				6FBG; 6FBH; 6FBI; 6N7W; 6N9U; 6N9V; 6N9W; 6N9X; 6P7E; 6Q4U; 6Q4V; 6XBU; 
				7OWF; 7ZUS; 7ZX0; 7ZX1; 8D33; 8D37; 8D3R; 8D42; 8E23; 8E24; 8G5I; 8G5J; 
				8G5K; 8G5L; 8G5M; 8G5N; 8G5O; 8G5P; 8GD7; 8OO6; 8OOY; 8T7E; 8UDK; 8UDL; 
				8V54; 8V55; 8V5D; 8V5R; 8XJR; 8XK9; 9FM3; 9FMF
			
			

			» more