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PROSITE entry PS00447


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General information about the entry

Entry name [info] DNA_POLYMERASE_A
Accession [info] PS00447
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-NOV-1995 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00412

Name and characterization of the entry

Description [info] DNA polymerase family A signature.
Pattern [info] 
R-x(2)-[GSAV]-K-x(3)-[LIVMFY]-[AGQ]-x(2)-Y-x(2)-[GS]-x(3)-[LIVMA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 58 in 58 different sequences
Number of true positive hits 56 in 56 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 96.55 %
Recall (true positives / (true positives + false negatives)) 84.85 %

Comments [info]

Taxonomic range [info] Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 56 sequences 

DPM1_ARATH  (Q9LM93    ), DPO1F_THETH (P30313    ), DPO1T_THET8 (P52028    ), 

DPO1_AQUAE  (O67779    ), DPO1_BACCA  (Q04957    ), DPO1_BACSU  (O34996    ), 
DPO1_BORBU  (O51498    ), DPO1_CALBD  (Q59156    ), DPO1_CHLAA  (O08307    ), 
DPO1_DEIRA  (P52027    ), DPO1_ECOLI  (P00582    ), DPO1_GEOSE  (P52026    ), 
DPO1_HAEIN  (P43741    ), DPO1_HELPJ  (Q9ZJE9    ), DPO1_HELPY  (P56105    ), 
DPO1_LACLA  (Q9CDS1    ), DPO1_LACLM  (O32801    ), DPO1_MYCBO  (P0A551    ), 
DPO1_MYCLE  (P46835    ), DPO1_MYCTO  (P9WNU4    ), DPO1_MYCTU  (P9WNU5    ), 
DPO1_PSEAE  (Q9HT80    ), DPO1_RHILE  (Q9S1G2    ), DPO1_RICBR  (Q1RH76    ), 
DPO1_RICCN  (Q92GB7    ), DPO1_RICFE  (Q9RAA9    ), DPO1_RICHE  (Q9RLB6    ), 
DPO1_RICPR  (O05949    ), DPO1_RICTY  (Q9RLA0    ), DPO1_SALTY  (Q9F173    ), 
DPO1_STRPN  (P59199    ), DPO1_STRR6  (P59200    ), DPO1_THEAQ  (P19821    ), 
DPO1_THECA  (P80194    ), DPO1_THEFI  (O52225    ), DPO1_TREPA  (P74933    ), 
DPOG1_CHICK (Q92076    ), DPOG1_DROME (Q27607    ), DPOG1_HUMAN (P54098    ), 
DPOG1_MOUSE (P54099    ), DPOG1_RAT   (Q9QYV8    ), DPOG1_XENLA (Q91684    ), 
DPOG_NEUCR  (Q9Y767    ), DPOG_YEAST  (P15801    ), DPOLA_BPPM6 (P0DTK4    ), 
DPOLQ_CAEEL (A0FLQ6    ), DPOLQ_HUMAN (O75417    ), DPOLQ_MOUSE (Q8CGS6    ), 
DPOL_BPE32  (B0FIL5    ), DPOL_BPMD2  (O64235    ), DPOL_BPML5  (Q05254    ), 
DPOL_BPSP1  (P30314    ), DPOL_BPSP2  (P06225    ), DPOL_BPT3   (P20311    ), 
DPOL_BPT5   (P19822    ), DPOL_BPT7   (P00581    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

DPO1_SYNY3  (Q55971    ), DPOG_PICPA  (Q01941    ), DPOG_SCHPO  (Q12704    ), 

DPOLN_HUMAN (Q7Z5Q5    ), DPOLN_MOUSE (Q7TQ07    ), DPOLQ_DROME (O18475    ), 
POLIA_ARATH (F4I6M1    ), POLIA_ORYSJ (Q6Z4T5    ), POLIB_ARATH (Q84ND9    ), 
POLIB_ORYSJ (Q6Z4T3    )
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

AGGC_ECOLX  (P46005    ), FA83B_MOUSE (Q0VBM2    )


				
	

	

		PDB
[Detailed view]		
		
			161 PDB
			


			1BGX; 1D8Y; 1D9D; 1D9F; 1DPI; 1JXE; 1KFD; 1KFS; 1KLN; 1KRP; 1KSP; 1KTQ; 
			
				1L3S; 1L3T; 1L3U; 1L3V; 1L5U; 1LV5; 1NJX; 1NJY; 1NJZ; 1NK0; 1NK4; 1NK5; 
				1NK6; 1NK7; 1NK8; 1NK9; 1NKB; 1NKC; 1NKE; 1QSL; 1QSS; 1QSY; 1QTM; 1SKR; 
				1SKS; 1SKW; 1SL0; 1SL1; 1SL2; 1T7P; 1T8E; 1TAQ; 1TAU; 1TK0; 1TK5; 1TK8; 
				1TKD; 1U45; 1U47; 1U48; 1U49; 1U4B; 1UA1; 1X9M; 1X9S; 1X9W; 1XC9; 1XWL; 
				1ZYQ; 2AJQ; 2BDP; 2HHX; 2KFN; 2KFZ; 2KTQ; 2KZM; 2KZZ; 3BDP; 3EYZ; 3EZ5; 
				3IKM; 3KTQ; 3LWL; 3LWM; 3M8R; 3M8S; 3OJS; 3OJU; 3PO4; 3PO5; 3PY8; 3RR7; 
				3RR8; 3RRG; 3RRH; 3RTV; 3SV3; 3SV4; 3SYZ; 3SZ2; 3T3F; 4BDP; 4BWJ; 4BWM; 
				4C8K; 4C8L; 4C8M; 4C8N; 4C8O; 4CCH; 4DF4; 4DF8; 4DFJ; 4DFK; 4DFM; 4DFP; 
				4DLE; 4DLG; 4ELT; 4ELU; 4ELV; 4KTQ; 4N56; 4N5S; 4X0P; 4X0Q; 4XIU; 4ZTU; 
				4ZTZ; 5C51; 5C52; 5C53; 5E41; 5IKN; 5KTQ; 5NKL; 5O7T; 5OXJ; 5SZT; 5W6K; 
				5W6Q; 5YTC; 5YTD; 5YTE; 5YTF; 5YTG; 5YTH; 5Z3N; 6FBC; 6FBD; 6FBE; 6FBF; 
				6FBG; 6FBH; 6FBI; 6N7W; 6N9U; 6N9V; 6N9W; 6N9X; 6P7E; 6Q4U; 6Q4V; 7OWF; 
				7ZUS; 7ZX0; 7ZX1; 8E23; 8E24
			
			

			» more