PROSITE entry PS00452
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00452 |
| Entry name [info] | GUANYLATE_CYCLASE_1 |
| Accession [info] | PS00452 |
| Entry type [info] | PATTERN |
| Date [info] |
01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00425 |
Name and characterization of the entry
| Description [info] | Guanylate cyclase signature. |
| Pattern [info] |
[GD]-[VI]-[LIVM]-x(0,1)-[GS]-x(5)-[FY]-x-[LIVM]-[FYWL]-[GS]-[DNTHKWE]- [DNTAS]-[IV]-[DNTAY]-x(5)-[DEC]. |
Numerical results [info]
| Total number of hits | 145 in 115 different sequences |
| Number of true positive hits | 145 in 115 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 42 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 77.54 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 2 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
115 sequences
AC78C_DROME (Q9VP76), ADCY1_BOVIN (P19754), ADCY1_HUMAN (Q08828), ADCY1_MOUSE (O88444), ADCY2_DROME (Q9VW60), ADCY2_HUMAN (Q08462), ADCY2_MOUSE (Q80TL1), ADCY2_RAT (P26769), ADCY3_HUMAN (O60266), ADCY3_MOUSE (Q8VHH7), ADCY3_RAT (P21932), ADCY4_HUMAN (Q8NFM4), ADCY4_MOUSE (Q91WF3), ADCY4_RAT (P26770), ADCY5_CANLF (P30803), ADCY5_HUMAN (O95622), ADCY5_MOUSE (P84309), ADCY5_RABIT (P40144), ADCY5_RAT (Q04400), ADCY6_CANLF (P30804), ADCY6_HUMAN (O43306), ADCY6_MOUSE (Q01341), ADCY6_RAT (Q03343), ADCY7_BOVIN (Q29450), ADCY7_HUMAN (P51828), ADCY7_MOUSE (P51829), ADCY8_HUMAN (P40145), ADCY8_MOUSE (P97490), ADCY8_RAT (P40146), ADCY9_CHICK (Q9DGG6), ADCY9_HUMAN (O60503), ADCY9_MOUSE (P51830), ADCY9_XENLA (P98999), ANPRA_HUMAN (P16066), ANPRA_MOUSE (P18293), ANPRA_RAT (P18910), ANPRB_ANGJA (P55202), ANPRB_BOVIN (P46197), ANPRB_HUMAN (P20594), ANPRB_MOUSE (Q6VVW5), ANPRB_RAT (P16067), CYA1_DROME (P32870), CYA1_MYCBO (P0A4Y1), CYA1_MYCTO (P9WQ34), CYA1_MYCTU (P9WQ35), CYAA_DICDI (Q03100), CYAG_DICDI (Q03101), GC76C_DROME (Q7JQ32), GCY12_CAEEL (Q19187), GCY13_CAEEL (Q19768), GCY14_CAEEL (Q23310), GCY15_CAEEL (P91550), GCY17_CAEEL (X5M8U1), GCY18_CAEEL (G5EFQ0), GCY19_CAEBR (A8XQC7), GCY19_CAEEL (O16544), GCY1_CAEEL (Q09435), GCY20_CAEEL (O62179), GCY21_CAEEL (O16715), GCY22_CAEEL (Q9XTY1), GCY23_CAEEL (G5EEE9), GCY28_CAEEL (Q86GV3), GCY2_CAEEL (Q10029), GCY31_CAEEL (Q86C56), GCY32_CAEEL (Q6DNF7), GCY33_CAEEL (P90895), GCY34_CAEEL (P92006), GCY35_CAEEL (O02298), GCY36_CAEEL (Q6DNF4), GCY37_CAEEL (Q6DNF3), GCY3E_DROME (Q07553), GCY3_CAEEL (Q10028), GCY4_CAEBR (A8WPG9), GCY4_CAEEL (Q23681), GCY5_CAEEL (Q23682), GCY6_CAEEL (N1NVB7), GCY7_CAEEL (H2L002), GCY8E_DROME (Q8INF0), GCY9_CAEEL (E7EAU8), GCYA1_BOVIN (P19687), GCYA1_CANLF (Q4ZHS0), GCYA1_HUMAN (Q02108), GCYA1_MOUSE (Q9ERL9), GCYA1_RAT (P19686), GCYA2_HUMAN (P33402), GCYA2_RAT (Q9WVI4), GCYB1_BOVIN (P16068), GCYB1_CANLF (Q4ZHR9), GCYB1_HUMAN (Q02153), GCYB1_MOUSE (O54865), GCYB1_RAT (P20595), GCYB2_HUMAN (O75343), GCYB2_RAT (P22717), GCYDA_DROME (Q9VEU6), GCYDB_DROME (Q9VEU5), GCYH_DROME (Q07093), GCY_STRPU (P16065), GUC2C_CAVPO (P70106), GUC2C_HUMAN (P25092), GUC2C_MOUSE (Q3UWA6), GUC2C_PIG (P55204), GUC2C_RAT (P23897), GUC2D_BOVIN (P55203), GUC2D_CANLF (O19179), GUC2D_HUMAN (Q02846), GUC2D_MOUSE (A0A0U1RPR8), GUC2D_RAT (P51839), GUC2E_MOUSE (P52785), GUC2E_RAT (P51840), GUC2F_BOVIN (O02740), GUC2F_HUMAN (P51841), GUC2F_MOUSE (Q5SDA5), GUC2F_RAT (P51842), GUC2G_MOUSE (Q6TL19), GUC2G_RAT (P55205)» more
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| UniProtKB/Swiss-Prot False negative sequences |
42 sequences
ACXE_DROME (Q9VK50), ADCYA_HUMAN (Q96PN6), ADCYA_MOUSE (Q8C0T9), ADCYA_RABIT (Q866F4), ADCYA_RAT (Q9Z286), CYAA_NEUCR (Q01631), CYAD_DICDI (Q55F68), DAF11_CAEEL (Q8I4N4), GCA_DICDI (Q553Y7), GCY10_CAEEL (B1Q257), GCY11_CAEEL (Q18331), GCY25_CAEEL (A0A078BQP2), GCY27_CAEEL (Q9XU42), GCY29_CAEEL (O62026), GCY8_CAEEL (Q9GYQ4), GCYA_PLAF7 (Q8IHY1), GCYB_PLABA (A0A509APX1), GCYB_PLAF7 (Q8IDA0), GCY_TOXGG (S7VVK4), LIPJ_MYCTU (O07732), PAL1F_EUGGR (P84738), PALFB_EUGGR (P84737), PALST_EUGGR (P84739), PBL1F_EUGGR (P84742), PBLFB_EUGGR (P84741), PBLST_EUGGR (P84743), PCYAA_EUGGR (Q8S9F2), PCYAA_EUGLO (Q76L34), PCYAB_EUGGR (Q8S9F1), PCYAB_EUGLO (Q76L33), PYCC1_ECOLX (P0DV24), PYCC2_ECOLX (P0DV26), PYCC_BURCE (A0A0J5ZXG5), PYCC_GULMO (P0DV42), PYCC_PSEAI (P0DV40), PYCC_RHOS2 (A0A1V0HUX5), PYCC_STAAU (P0DV38), PYCC_TREPO (A0A1T4LJ54), PYCC_XANPE (P0DV28), YR818_MIMIV (Q5UQG7), YR826_MIMIV (Q7T6X2), YR831_MIMIV (Q7T6Y2)» more |
| PDB [Detailed view] |
47 PDB
1AB8; 1AZS; 1CJK; 1CJT; 1CJU; 1CJV; 1CS4; 1CUL; 1TL7; 1U0H; 1YK9; 2GVD; 2GVZ; 2WZ1; 3C14; 3C15; 3C16; 3G82; 3MAA; 3UVJ; 4NI2; 4P2F; 4P2M; 4P2X; 6JT0; 6JT1; 6JT2; 7D9R; 7D9S; 7D9T; 7D9U; 7YZ9; 7YZI; 7YZK; 8FX4; 8HBE; 8HBF; 8HBH; 8SL3; 8SL4; 9BCL; 9BCN; 9BCO; 9BCP; 9BCQ; 9BCS; 9BCV » more |