PROSITE logo

PROSITE entry PS00460


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] GLUTATHIONE_PEROXID_1
Accession [info] PS00460
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-JAN-2008 DATA UPDATE;
03-MAY-2023 INFO UPDATE.
PROSITE Doc. [info] PDOC00396

Name and characterization of the entry

Description [info] Glutathione peroxidases active site.
Pattern [info] 
[GNDRC]-[RKHNQFYCS]-x-[LIVMFCS]-[LIVMF](2)-x-N-[VT]-x-[STCA]-x-[CU]-
[GA]-x-[TA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2023_02 which contains 569'516 sequence entries.


Total number of hits 97 in 97 different sequences
Number of true positive hits 97 in 97 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 15
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.61 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 97 sequences 

BSAA_BACSU  (P52035    ), BSAA_HALH5  (Q9Z9N7    ), BTUE_ECOLI  (P06610    ), 

GPO_LACLA   (Q9CFV1    ), GPO_LACLM   (O32770    ), GPWA_PSEWI  (O08368    ), 
GPX1_ARATH  (P52032    ), GPX1_BOVIN  (P00435    ), GPX1_CAEEL  (O02621    ), 
GPX1_CALJA  (Q0EF99    ), GPX1_CHLRE  (P83564    ), GPX1_HELAN  (O23970    ), 
GPX1_HUMAN  (P07203    ), GPX1_HYLLA  (Q4AEI2    ), GPX1_MACFU  (Q865R2    ), 
GPX1_MOUSE  (P11352    ), GPX1_PANTR  (Q0EFA0    ), GPX1_PEA    (O24296    ), 
GPX1_PIG    (Q8MJ14    ), GPX1_PONPY  (Q4AEI3    ), GPX1_RABIT  (P11909    ), 
GPX1_RAT    (P04041    ), GPX1_SAPAP  (Q4AEI1    ), GPX1_SCHMA  (Q00277    ), 
GPX1_SCHPO  (O59858    ), GPX1_SYNY3  (P74250    ), GPX1_YEAST  (P36014    ), 
GPX2_ARATH  (O04922    ), GPX2_CAEEL  (O62327    ), GPX2_CALJA  (Q0EF98    ), 
GPX2_HUMAN  (P18283    ), GPX2_HYLLA  (Q4AEH9    ), GPX2_MACFU  (Q4AEH8    ), 
GPX2_MOUSE  (Q9JHC0    ), GPX2_PONPY  (Q4AEI0    ), GPX2_RAT    (P83645    ), 
GPX2_SAPAP  (Q4AEH7    ), GPX2_SYNY3  (P73824    ), GPX2_YEAST  (P38143    ), 
GPX3_ARATH  (O22850    ), GPX3_BOVIN  (P37141    ), GPX3_CAEEL  (Q95003    ), 
GPX3_CANAL  (Q59WD3    ), GPX3_HUMAN  (P22352    ), GPX3_HYLLA  (Q4AEH5    ), 
GPX3_MACFU  (Q4AEH4    ), GPX3_MOUSE  (P46412    ), GPX3_PONPY  (Q5RFG3    ), 
GPX3_RAT    (P23764    ), GPX3_SAPAP  (Q4AEH3    ), GPX3_YEAST  (P40581    ), 
GPX4_ARATH  (Q8L910    ), GPX4_BOVIN  (Q9N2J2    ), GPX4_CALJA  (Q32QL6    ), 
GPX4_CITSI  (Q06652    ), GPX4_GOSHI  (O49069    ), GPX4_HELAN  (O23968    ), 
GPX4_HUMAN  (P36969    ), GPX4_HYLLA  (Q4AEH1    ), GPX4_MACFU  (Q4AEH0    ), 
GPX4_MESCR  (Q9LEF0    ), GPX4_MOUSE  (O70325    ), GPX4_NICSY  (P30708    ), 
GPX4_PIG    (P36968    ), GPX4_PONPY  (Q4AEH2    ), GPX4_RAT    (P36970    ), 
GPX4_SAPAP  (Q4AEG9    ), GPX4_SOLLC  (O24031    ), GPX4_SPIOL  (O23814    ), 
GPX4_TOBAC  (Q9FXS3    ), GPX5_ARATH  (Q9LYB4    ), GPX5_CANLF  (O46607    ), 
GPX5_CHLRE  (O22448    ), GPX5_HUMAN  (O75715    ), GPX5_MACFA  (P28714    ), 
GPX5_MOUSE  (P21765    ), GPX5_PIG    (O18994    ), GPX5_RAT    (P30710    ), 
GPX6_ARATH  (O48646    ), GPX6_HUMAN  (P59796    ), GPX6_MOUSE  (Q91WR8    ), 
GPX6_RAT    (Q64625    ), GPX7_ARATH  (Q9SZ54    ), GPX7_BOVIN  (A6QLY2    ), 
GPX7_HUMAN  (Q96SL4    ), GPX7_MOUSE  (Q99LJ6    ), GPX8_ARATH  (Q8LBU2    ), 
GPXA_NEIMA  (P0A0T4    ), GPXA_NEIMB  (P0A0T5    ), GPXA_NEIMC  (P0C2T0    ), 
GPXA_NEIMF  (A1KV41    ), GPXC_BRUMA  (P67877    ), GPXC_BRUPA  (P67878    ), 
GPXC_DIRIM  (P52033    ), GPXC_WUCBA  (P35666    ), GPX_MCV1    (Q98234    ), 
GPX_PROCL   (G9JJU2    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 15 sequences 

BSAA_STAAC  (Q5HGC7    ), BSAA_STAAM  (P64290    ), BSAA_STAAN  (P99097    ), 

BSAA_STAAR  (Q6GHD0    ), BSAA_STAAS  (Q6G9Q8    ), BSAA_STAAW  (P64291    ), 
BSAA_STAEQ  (Q5HKZ3    ), BSAA_STAES  (Q8CSR9    ), GPX8A_XENLA (Q6IRC8    ), 
GPX8B_XENLA (Q5U583    ), GPX8_BOVIN  (Q2NL01    ), GPX8_DANRE  (Q7ZV14    ), 
GPX8_HUMAN  (Q8TED1    ), GPX8_MOUSE  (Q9D7B7    ), GPX8_TETNG  (Q4RSM6    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

GPX4_PINPS  (P81087    )


				
	

	

		PDB
[Detailed view]		
		
			20 PDB
			


			1GP1; 2HE3; 2I3Y; 2OBI; 2P31; 2V1M; 3CMI; 5H5Q; 5H5R; 5H5S; 5L71; 6ELW; 
			
				6HKQ; 6HN3; 7FC2; 7L8K; 7L8L; 7L8M; 7L8Q; 7L8R
			
			

			» more