PROSITE entry PS00460
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General information about the entry
| Entry name [info] | GLUTATHIONE_PEROXID_1 |
| Accession [info] | PS00460 |
| Entry type [info] | PATTERN |
| Date [info] |
01-MAY-1991 CREATED;
01-JAN-2008 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00396 |
Name and characterization of the entry
| Description [info] | Glutathione peroxidases active site. |
| Pattern [info] |
[GNDRC]-[RKHNQFYCS]-x-[LIVMFCS]-[LIVMF](2)-x-N-[VT]-x-[STCA]-x-[CU]- [GA]-x-[TA]. |
Numerical results [info]
| Total number of hits | 97 in 97 different sequences |
| Number of true positive hits | 97 in 97 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 15 |
| Number of 'partial' sequences | 1 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 86.61 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 12 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
97 sequences
BSAA_BACSU (P52035), BSAA_HALH5 (Q9Z9N7), BTUE_ECOLI (P06610), GPO_LACLA (Q9CFV1), GPO_LACLM (O32770), GPWA_PSEWI (O08368), GPX1_ARATH (P52032), GPX1_BOVIN (P00435), GPX1_CAEEL (O02621), GPX1_CALJA (Q0EF99), GPX1_CHLRE (P83564), GPX1_HELAN (O23970), GPX1_HUMAN (P07203), GPX1_HYLLA (Q4AEI2), GPX1_MACFU (Q865R2), GPX1_MOUSE (P11352), GPX1_PANTR (Q0EFA0), GPX1_PEA(O24296), GPX1_PIG(Q8MJ14), GPX1_PONPY (Q4AEI3), GPX1_RABIT (P11909), GPX1_RAT(P04041), GPX1_SAPAP (Q4AEI1), GPX1_SCHMA (Q00277), GPX1_SCHPO (O59858), GPX1_SYNY3 (P74250), GPX1_YEAST (P36014), GPX2_ARATH (O04922), GPX2_CAEEL (O62327), GPX2_CALJA (Q0EF98), GPX2_HUMAN (P18283), GPX2_HYLLA (Q4AEH9), GPX2_MACFU (Q4AEH8), GPX2_MOUSE (Q9JHC0), GPX2_PONPY (Q4AEI0), GPX2_RAT(P83645), GPX2_SAPAP (Q4AEH7), GPX2_SYNY3 (P73824), GPX2_YEAST (P38143), GPX3_ARATH (O22850), GPX3_BOVIN (P37141), GPX3_CAEEL (Q95003), GPX3_CANAL (Q59WD3), GPX3_HUMAN (P22352), GPX3_HYLLA (Q4AEH5), GPX3_MACFU (Q4AEH4), GPX3_MOUSE (P46412), GPX3_PONPY (Q5RFG3), GPX3_RAT(P23764), GPX3_SAPAP (Q4AEH3), GPX3_YEAST (P40581), GPX4_ARATH (Q8L910), GPX4_BOVIN (Q9N2J2), GPX4_CALJA (Q32QL6), GPX4_CITSI (Q06652), GPX4_GOSHI (O49069), GPX4_HELAN (O23968), GPX4_HUMAN (P36969), GPX4_HYLLA (Q4AEH1), GPX4_MACFU (Q4AEH0), GPX4_MESCR (Q9LEF0), GPX4_MOUSE (O70325), GPX4_NICSY (P30708), GPX4_PIG(P36968), GPX4_PONPY (Q4AEH2), GPX4_RAT(P36970), GPX4_SAPAP (Q4AEG9), GPX4_SOLLC (O24031), GPX4_SPIOL (O23814), GPX4_TOBAC (Q9FXS3), GPX5_ARATH (Q9LYB4), GPX5_CANLF (O46607), GPX5_CHLRE (O22448), GPX5_HUMAN (O75715), GPX5_MACFA (P28714), GPX5_MOUSE (P21765), GPX5_PIG(O18994), GPX5_RAT(P30710), GPX6_ARATH (O48646), GPX6_HUMAN (P59796), GPX6_MOUSE (Q91WR8), GPX6_RAT(Q64625), GPX7_ARATH (Q9SZ54), GPX7_BOVIN (A6QLY2), GPX7_HUMAN (Q96SL4), GPX7_MOUSE (Q99LJ6), GPX8_ARATH (Q8LBU2), GPXA_NEIMA (P0A0T4), GPXA_NEIMB (P0A0T5), GPXA_NEIMC (P0C2T0), GPXA_NEIMF (A1KV41), GPXC_BRUMA (P67877), GPXC_BRUPA (P67878), GPXC_DIRIM (P52033), GPXC_WUCBA (P35666), GPX_MCV1(Q98234), GPX_PROCL (G9JJU2)» more
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| UniProtKB/Swiss-Prot False negative sequences |
15 sequences
BSAA_STAAC (Q5HGC7), BSAA_STAAM (P64290), BSAA_STAAN (P99097), BSAA_STAAR (Q6GHD0), BSAA_STAAS (Q6G9Q8), BSAA_STAAW (P64291), BSAA_STAEQ (Q5HKZ3), BSAA_STAES (Q8CSR9), GPX8A_XENLA (Q6IRC8), GPX8B_XENLA (Q5U583), GPX8_BOVIN (Q2NL01), GPX8_DANRE (Q7ZV14), GPX8_HUMAN (Q8TED1), GPX8_MOUSE (Q9D7B7), GPX8_TETNG (Q4RSM6)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
GPX4_PINPS (P81087) |
| PDB [Detailed view] |
26 PDB
1GP1; 2HE3; 2I3Y; 2OBI; 2P31; 2V1M; 3CMI; 5H5Q; 5H5R; 5H5S; 5L71; 6ELW; 6HKQ; 6HN3; 7FC2; 7L8K; 7L8L; 7L8M; 7L8Q; 7L8R; 7U4I; 7U4J; 7U4K; 7U4L; 7U4M; 7U4N » more |