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PROSITE entry PS00470


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General information about the entry

Entry name [info] IDH_IMDH
Accession [info] PS00470
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00389

Name and characterization of the entry

Description [info] Isocitrate and isopropylmalate dehydrogenases signature.
Pattern [info]
[NSK]-[LIMYTV]-[FYDNH]-[GEA]-[DNGSTY]-[IMVYL]-x-[STGDN]-[DN]-x(1,2)-
[SGAP]-x(3,4)-[GE]-[STG]-[LIVMPA]-[GA]-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 408 in 408 different sequences
Number of true positive hits 407 in 407 different sequences
Number of 'unknown' hits 1
Number of false positive hits 0
Number of false negative sequences 9
Number of 'partial' sequences 6
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.84 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
407 sequences

AKSF_METJA  (Q58991), AMT6_ALTAL  (C9K7B7), DLPA_LEGPH  (Q48806), 
DMLA_ECOLI  (P76251), GLOI_GLAL2  (S3DB74), HICDH_PYRHO (O59394), 
HTYC_ASPRU  (K0E689), ICDHC_ARATH (Q9SRZ6), ICDHP_ARATH (Q8LPJ5), 
ICDHX_ARATH (Q9SLK0), IDH1_AJECA  (O13302), IDH1_CANTR  (O13285), 
IDH1_COLMA  (P41560), IDH1_KLULA  (O94229), IDH1_MYCBO  (P65098), 
IDH1_MYCTO  (P9WKL0), IDH1_MYCTU  (P9WKL1), IDH1_PSYS3  (A0A5A4WIX0), 
IDH1_SCHPO  (O13696), IDH1_YEAST  (P28834), IDH2_CANTR  (O13294), 
IDH2_KLULA  (O94230), IDH2_SCHPO  (Q9USP8), IDH2_YEAST  (P28241), 
IDH3A_BOVIN (P41563), IDH3A_CAEEL (Q93714), IDH3A_DROME (Q9VWH4), 
IDH3A_HUMAN (P50213), IDH3A_MACFA (Q28480), IDH3A_MOUSE (Q9D6R2), 
IDH3A_PONAB (Q5R678), IDH3A_RAT   (Q99NA5), IDH3B_BOVIN (O77784), 
IDH3B_CAEEL (Q93353), IDH3B_HUMAN (O43837), IDH3B_MACFA (Q28479), 
IDH3B_PONAB (Q5RBT4), IDH3B_RAT   (Q68FX0), IDH3G_BOVIN (Q58CP0), 
IDH3G_HUMAN (P51553), IDH3G_MACFA (P41564), IDH5_ARATH  (Q945K7), 
IDH6_ARATH  (Q8LG77), IDHA_DICDI  (Q55BI2), IDHB_DICDI  (Q54B68), 
IDHC_BOVIN  (Q9XSG3), IDHC_DICDI  (Q75JR3), IDHC_HUMAN  (O75874), 
IDHC_MICME  (Q9Z2K9), IDHC_MICOH  (Q9Z2K8), IDHC_MOUSE  (O88844), 
IDHC_PONAB  (Q5R9C5), IDHC_RAT(P41562), IDHC_SHEEP  (Q6XUZ5), 
IDHC_SOLTU  (P50217), IDHC_SOYBN  (Q06197), IDHC_TOBAC  (P50218), 
IDHC_YEAST  (P41939), IDHG1_MOUSE (P70404), IDHG1_RAT   (P41565), 
IDHH_YEAST  (P53982), IDHP_ASPNG  (P79089), IDHP_BOVIN  (Q04467), 
IDHP_DICDI  (Q75JR2), IDHP_HUMAN  (P48735), IDHP_MACFA  (Q4R502), 
IDHP_MEDSA  (Q40345), IDHP_MOUSE  (P54071), IDHP_PIG(P33198), 
IDHP_RAT(P56574), IDHP_SCHPO  (O14254), IDHP_YEAST  (P21954), 
IDH_AQUAE   (O67480), IDH_ARCFU   (O29610), IDH_BACSU   (P39126), 
IDH_CALNO   (P96318), IDH_COXBU   (Q9ZH99), IDH_ECOLI   (P08200), 
IDH_HALVD   (D4GU92), IDH_HELPJ   (Q9ZN36), IDH_HELPY   (P56063), 
IDH_NOSS1   (P50214), IDH_PSEAB   (Q02NB5), IDH_RICBR   (Q1RJU4), 
IDH_RICCN   (Q92IR7), IDH_RICFE   (Q4UKR1), IDH_RICPR   (Q9ZDR0), 
IDH_RICTY   (Q68XA5), IDH_SPHYA   (P50215), IDH_STAAC   (Q5HF79), 
IDH_STAAM   (P65099), IDH_STAAN   (P99167), IDH_STAAR   (Q6GG12), 
IDH_STAAS   (Q6G8N2), IDH_STAAW   (Q8NW61), IDH_STAEQ   (Q5HNL1), 
IDH_STAES   (Q8CNX4), IDH_STRMU   (Q59940), IDH_STRSL   (Q59985), 
IDH_SYNY3   (P80046), IDH_THET8   (P33197), LEU31_ARATH (Q9FMT1), 
LEU31_BORBR (Q7WNM3), LEU31_BRADU (Q89XA0), LEU31_DECAR (Q47HR1), 
LEU32_ARATH (P93832), LEU32_BORBR (Q7WKH4), LEU32_BRADU (Q89X19), 
LEU32_DECAR (Q479H7), LEU33_ARATH (Q9SA14), LEU3A_ASPNG (P87256), 
LEU3B_ASPNG (P87257), LEU3_ACIAD  (Q6FEV6), LEU3_ACIFR  (Q56268), 
LEU3_AGRFC  (P24404), LEU3_ALBFT  (Q21XI1), LEU3_ALIF1  (Q5E857), 
LEU3_ANADE  (Q2IJK7), LEU3_AQUAE  (O66607), LEU3_ARCFU  (O29627), 
LEU3_AROAE  (Q5P1J6), LEU3_ARTPT  (Q00412), LEU3_AZOVI  (P96197), 
LEU3_BACAN  (Q81T67), LEU3_BACC1  (Q73B99), LEU3_BACCA  (P05644), 
LEU3_BACCR  (Q81G11), LEU3_BACCZ  (Q63DX7), LEU3_BACFN  (Q5LAB4), 
LEU3_BACFR  (P54354), LEU3_BACHK  (Q6HLF2), LEU3_BACLD  (Q65GI9), 
LEU3_BACSU  (P05645), LEU3_BACTN  (Q8A6M0), LEU3_BEUC1  (C5C2I9), 
LEU3_BLAAD  (Q8NKB8), LEU3_BLOFL  (Q7VQJ7), LEU3_BLOPB  (Q493R1), 
LEU3_BORA1  (Q2KYL5), LEU3_BORPA  (Q7W929), LEU3_BORPE  (Q7VY73), 
LEU3_BRANA  (P29102), LEU3_BRUA2  (Q2YL58), LEU3_BRUAB  (Q579B1), 
LEU3_BRUME  (Q8YCX4), LEU3_BRUSU  (Q8FVF3), LEU3_BUCAI  (P56933), 
LEU3_BUCAP  (O85064), LEU3_BUCBP  (P59515), LEU3_BUCCC  (Q5WPZ9), 
LEU3_BUCDN  (O85071), LEU3_BUCML  (Q9EVG3), LEU3_BUCPS  (P59027), 
LEU3_BUCRP  (P48572), LEU3_BUCTS  (O31292), LEU3_BUCUA  (Q9EVG6), 
LEU3_BUCUD  (Q9EVE1), LEU3_BUCUE  (Q9EVH5), LEU3_BUCUH  (Q9EVH8), 
LEU3_BUCUL  (Q9AQC8), LEU3_BUCUM  (Q9EVG9), LEU3_BUCUN  (Q9EVI7), 
LEU3_BUCUO  (Q9EVI1), LEU3_BUCUS  (Q9EVI4), LEU3_BURL3  (Q393X4), 
LEU3_BURM1  (Q845W3), LEU3_BURMA  (Q62AI9), LEU3_BURP1  (Q3JKG9), 
LEU3_BURPS  (Q63JL2), LEU3_BURTA  (Q2T7H6), LEU3_CALS4  (Q8RDK0), 
LEU3_CAMJE  (Q9PLW0), LEU3_CAMJR  (Q5HS77), LEU3_CANAX  (P87186), 
LEU3_CANBO  (Q01987), LEU3_CANGA  (O14429), LEU3_CANMA  (P07139), 
LEU3_CARHZ  (Q3AEQ2), LEU3_CAUVC  (Q9ABN3), LEU3_CERS4  (Q3IZJ3), 
LEU3_CHLCH  (Q3APC4), LEU3_CHLL3  (Q3B595), LEU3_CHLTE  (P59028), 
LEU3_CHRSD  (Q1QUR0), LEU3_CHRVO  (Q7NUC2), LEU3_CLAM3  (A5CPZ4), 
LEU3_CLASE  (B0RIP4), LEU3_CLOAB  (Q97EE2), LEU3_CLOPA  (P31958), 
LEU3_COLP3  (Q47WG3), LEU3_CORA7  (C3PFX5), LEU3_CORDI  (Q6NHM7), 
LEU3_COREF  (Q8FPV5), LEU3_CORGB  (A4QDP9), LEU3_CORGL  (P94631), 
LEU3_CORJK  (Q4JUQ0), LEU3_CORK4  (C4LJH3), LEU3_CORU7  (B1VG35), 
LEU3_CUPMC  (Q1LKH7), LEU3_CUPPJ  (Q46YW0), LEU3_CYBJA  (P08791), 
LEU3_DEBHA  (Q6B458), LEU3_DEHM1  (Q3Z896), LEU3_DEHMC  (Q3ZXI7), 
LEU3_DEIGD  (Q1IZK2), LEU3_DEIRA  (Q9RTH9), LEU3_DESHY  (Q24XT2), 
LEU3_DESPS  (Q6ANR1), LEU3_DIURU  (Q9HDQ5), LEU3_ECO57  (Q8X9Z9), 
LEU3_ECOL6  (Q8FL76), LEU3_ECOLI  (P30125), LEU3_ECOUT  (Q1RGC4), 
LEU3_EREGS  (O60027), LEU3_FRACC  (Q2J6V8), LEU3_GEOKA  (Q5KWJ4), 
LEU3_GEOMG  (Q39Y29), LEU3_GEOSL  (Q748X2), LEU3_GLOVI  (Q7NFH4), 
LEU3_GLUOX  (Q5FUG5), LEU3_HAEI8  (Q4QLS3), LEU3_HAEIN  (P43860), 
LEU3_HAHCH  (Q2SJD6), LEU3_HALH5  (Q9K8E9), LEU3_HAPCH  (Q12545), 
LEU3_HELHP  (Q7VH33), LEU3_HEYCO  (P12010), LEU3_HYDCU  (Q31HI0), 
LEU3_JANSC  (Q28W67), LEU3_KLULA  (P23390), LEU3_KLUMA  (P41766), 
LEU3_KODOH  (P41926), LEU3_LACLA  (Q02143), LEU3_LEIXX  (Q6AEP6), 
LEU3_LEPIC  (Q72RH7), LEU3_LEPIN  (P24015), LEU3_LISIN  (Q92A27), 
LEU3_LISMF  (Q71Y34), LEU3_LISMO  (Q8Y5R8), LEU3_MANSM  (Q65V05), 
LEU3_MAUEX  (Q96WT9), LEU3_MAUHU  (Q6PY58), LEU3_METCA  (Q606F4), 
LEU3_METJA  (Q58130), LEU3_METTH  (O27441), LEU3_MOOTA  (Q2RGA0), 
LEU3_MYCA1  (A0QJC2), LEU3_MYCBO  (P94929), LEU3_MYCBP  (A1KMY9), 
LEU3_MYCBT  (C1AGB0), LEU3_MYCGI  (A4TE12), LEU3_MYCLB  (B8ZS15), 
LEU3_MYCLE  (O33117), LEU3_MYCMM  (B2HIH1), LEU3_MYCPA  (Q73VI1), 
LEU3_MYCSJ  (A3PXQ2), LEU3_MYCSK  (A1UE98), LEU3_MYCSS  (Q1BAR4), 
LEU3_MYCTA  (A5U706), LEU3_MYCTO  (P9WKK8), LEU3_MYCTU  (P9WKK9), 
LEU3_MYCUA  (A0PPY6), LEU3_MYCVP  (A1T6Z4), LEU3_NEIG1  (Q5F8T6), 
LEU3_NEILA  (P50180), LEU3_NEIMA  (Q9JU79), LEU3_NEIMB  (Q9JZI9), 
LEU3_NEUCR  (P34738), LEU3_NITEU  (Q82WI6), LEU3_NITMU  (Q2Y7Q8), 
LEU3_NITOC  (Q3JCC4), LEU3_NITV2  (Q726X1), LEU3_NITWN  (Q3SNU3), 
LEU3_NOCFA  (Q5YRX2), LEU3_NOSS1  (Q8YXA2), LEU3_NOVAD  (Q2G4X5), 
LEU3_OCEIH  (Q8EN68), LEU3_OLEA2  (Q30WD0), LEU3_PARM1  (Q2VZV2), 
LEU3_PARMW  (Q7U840), LEU3_PARS2  (A8L554), LEU3_PASMU  (Q9CJN6), 
LEU3_PECAS  (Q6D0G7), LEU3_PELUB  (Q4FP17), LEU3_PHACH  (O59930), 
LEU3_PHOLL  (Q7N128), LEU3_PHOPR  (Q6LV25), LEU3_PICAN  (P34733), 
LEU3_PICST  (O94114), LEU3_PRIM3  (P41019), LEU3_PROM9  (Q31B91), 
LEU3_PROMA  (Q7VC80), LEU3_PROMM  (Q7V842), LEU3_PROMP  (Q7V1R9), 
LEU3_PROMT  (Q46LE2), LEU3_PSE14  (Q48K97), LEU3_PSEAE  (Q51375), 
LEU3_PSEF5  (Q4KF05), LEU3_PSEPF  (Q3KF21), LEU3_PSEPK  (Q88LE5), 
LEU3_PSESM  (Q884C0), LEU3_PSET1  (Q3IJS3), LEU3_PSEU2  (Q4ZUZ4), 
LEU3_PSYA2  (Q4FRV0), LEU3_PSYCK  (Q1QAF5), LEU3_RALN1  (Q8XXX5), 
LEU3_RHIEC  (Q2K2V0), LEU3_RHIJ3  (Q1MA50), LEU3_RHILO  (Q98E57), 
LEU3_RHIME  (Q92KY8), LEU3_RHOBA  (Q7UIE1), LEU3_RHOE4  (C0ZXM4), 
LEU3_RHOJR  (Q0S2H1), LEU3_RHOOB  (C1B2M3), LEU3_RHOP2  (Q2J3B4), 
LEU3_RHOPA  (Q6ND82), LEU3_RHOPB  (Q21CS1), LEU3_RHORT  (Q2RV53), 
LEU3_RUEPO  (Q5LWZ5), LEU3_SACD2  (Q21IY5), LEU3_SACEN  (A4FMQ2), 
LEU3_SACS2  (Q9UXB2), LEU3_SALCH  (Q57TE7), LEU3_SALPA  (Q5PDG2), 
LEU3_SALRD  (Q2S0M8), LEU3_SALTI  (Q8Z9I1), LEU3_SALTY  (P37412), 
LEU3_SCHPO  (P18869), LEU3_SHEON  (Q8E9N3), LEU3_SHIBS  (Q326G2), 
LEU3_SHIDS  (Q32K21), LEU3_SHIFL  (Q83SP1), LEU3_SHISS  (Q3Z5T7), 
LEU3_SHOC1  (Q5WEN4), LEU3_SODGM  (Q2NVW4), LEU3_SOLTU  (P29696), 
LEU3_SORMA  (Q6TWC4), LEU3_STAA3  (Q2FF66), LEU3_STAA8  (Q2FWK2), 
LEU3_STAAB  (Q2YUF1), LEU3_STAAC  (Q5HEE3), LEU3_STAAM  (P65100), 
LEU3_STAAN  (P65101), LEU3_STAAR  (Q6GF15), LEU3_STAAS  (Q6G7Q0), 
LEU3_STAAW  (Q8NVJ0), LEU3_STAEQ  (Q5HMF8), LEU3_STAES  (Q8CNL2), 
LEU3_STAHJ  (Q4L7U1), LEU3_STAS1  (Q49Z13), LEU3_STRAW  (Q82JN6), 
LEU3_STRCO  (O86504), LEU3_STRGG  (B1VZ57), LEU3_STRMU  (Q8DTG3), 
LEU3_STRR6  (Q8DPJ4), LEU3_STRT1  (Q5LZF3), LEU3_STRT2  (Q5M405), 
LEU3_SULDN  (Q30RK2), LEU3_SULTO  (P50455), LEU3_SYNC1  (Q3A3B2), 
LEU3_SYNE7  (Q31N34), LEU3_SYNJA  (Q2JTN8), LEU3_SYNJB  (Q2JL30), 
LEU3_SYNP6  (Q5MZ40), LEU3_SYNS9  (Q3AYS1), LEU3_SYNSC  (Q3AIH4), 
LEU3_SYNY3  (P73960), LEU3_THEAQ  (P24098), LEU3_THEFY  (Q47SB4), 
LEU3_THEMA  (Q9WZ26), LEU3_THET2  (P61494), LEU3_THET8  (Q5SIY4), 
LEU3_THETH  (P61495), LEU3_THEVB  (P59029), LEU3_THIDA  (Q3SHL3), 
LEU3_TRIV2  (Q3M8T9), LEU3_VIBCH  (Q9KP82), LEU3_VIBPA  (Q87SS8), 
LEU3_VIBVU  (Q8DEE0), LEU3_VIBVY  (Q7MP78), LEU3_WICAN  (Q9HDQ1), 
LEU3_WOLSU  (Q7M886), LEU3_XANAC  (Q8PH05), LEU3_XANC8  (Q4UYG2), 
LEU3_XANCP  (Q8P5L1), LEU3_XANE5  (Q3BPJ8), LEU3_XANOM  (Q2P762), 
LEU3_XANOR  (Q5H4C7), LEU3_XYLFA  (Q9PAX3), LEU3_XYLFT  (Q87BQ1), 
LEU3_YARLI  (P18120), LEU3_YEAST  (P04173), LEU3_YERPE  (Q8ZIG9), 
LEU3_YERPS  (Q66EM2), LEU3_ZYGBA  (Q9P3Y0), LEU3_ZYGRC  (Q96WI0), 
LEU3_ZYMMO  (Q5NPQ9), LEU3_ZYMTR  (Q9Y897), LYS12_SCHPO (O14104), 
LYS12_YEAST (P40495), TTUC1_AGRVI (Q44471), TTUC2_AGRVI (P70787), 
TTUC3_AGRVI (O34296), TTUC4_AGRVI (P70792), TTUC5_AGRVI (O34295), 
TTUC_BACSU  (P42958), TTUC_PSEPU  (Q51945)
» more

UniProtKB/Swiss-Prot
False negative sequences
9 sequences

IDH1_ARATH  (Q8LFC0), IDH2_ARATH  (P93032), IDH3_ARATH  (O81796), 
IDHG2_MOUSE (Q8BPC6), IDHG2_RAT   (Q4QQT5), LEU3_BIFLD  (B3DTF8), 
LEU3_BIFLO  (Q8G500), LEU3_BIFLS  (B7GUI8), LEU3_SYMTH  (Q67JY2)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
6 sequences

IDH3A_CANLF (P54836), IDH3A_MESAU (P86225), IDH3B_PIG   (P56472), 
IDH3G_PIG   (P41566), IDHC_NAEFO  (P83726), IDHC_PIG(P20304)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

IDH3A_PIG   (P56471)

		
PDB
[Detailed view]
189 PDB

1A05; 1AI2; 1AI3; 1BL5; 1CM7; 1CNZ; 1CW1; 1CW4; 1CW7; 1DPZ; 1DR0; 1DR8; 1G2U; 1GC8; 1GC9; 1GRO; 1GRP; 1HEX; 1HJ6; 1HQS; 1IDC; 1IDD; 1IDE; 1IDF; 1IDM; 1IKA; 1IPD; 1ISO; 1LWD; 1OSI; 1OSJ; 1P8F; 1PB1; 1PB3; 1SJS; 1T09; 1T0L; 1V53; 1V5B; 1VLC; 1W0D; 1WAL; 1WPW; 1XAA; 1XAB; 1XAC; 1XAD; 2AYQ; 2D1C; 2G4O; 2IV0; 2QFV; 2QFW; 2QFX; 2QFY; 2Y3Z; 2Y40; 2Y41; 2Y42; 2ZTW; 3BLV; 3BLW; 3BLX; 3FLK; 3FMX; 3ICD; 3INM; 3LCB; 3MAP; 3MAR; 3MAS; 3R8W; 3TY3; 3TY4; 3UDO; 3UDU; 3VKZ; 3VL2; 3VL3; 3VL4; 3VL6; 3VL7; 3VMJ; 3VML; 3WZV; 3WZW; 3WZX; 3WZY; 4AJ3; 4AJA; 4AJB; 4AJC; 4AJR; 4AJS; 4BNP; 4F7I; 4HCX; 4I3K; 4I3L; 4ICD; 4IWH; 4JA8; 4KZO; 4L03; 4L04; 4L06; 4P69; 4UMX; 4UMY; 4WUO; 4XRX; 4XS3; 4XXV; 5DE1; 5GRE; 5GRF; 5GRH; 5GRI; 5GRL; 5H3E; 5H3F; 5I95; 5I96; 5ICD; 5J32; 5J33; 5J34; 5K10; 5K11; 5L57; 5L58; 5LGE; 5M2E; 5SUN; 5SVF; 5SVN; 5SVO; 5TQH; 5YFM; 5YFN; 5YVT; 5YZH; 5YZI; 6ADG; 6ADI; 6B0Z; 6BKX; 6BKY; 6BKZ; 6BL0; 6BL1; 6BL2; 6ICD; 6IO0; 6KDE; 6KDF; 6KDY; 6KE3; 6L57; 6L59; 6O2Y; 6O2Z; 6PAY; 6Q6F; 6U4J; 6VEI; 6VFZ; 6VG0; 6XXY; 7CE3; 7ICD; 7PJM; 7PJN; 8BAY; 8GRB; 8GRD; 8GRG; 8GRH; 8GRU; 8GS5; 8HB9; 8ICD; 8VH9; 8VHA; 8VHB; 8VHC; 8VHD; 8VHE; 9ICD
» more