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PROSITE entry PS00471


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PURL: https://purl.expasy.org/prosite/signature/PS00471

Direct ScanProsite submission
General information about the entry

Entry name [info] SMALL_CYTOKINES_CXC
Accession [info] PS00471
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00434

Name and characterization of the entry

Description [info] Small cytokines (intercrine/chemokine) C-x-C subfamily signature.
Pattern [info]
C-x-C-[LIVMS]-x(4,6)-[LIVMFY]-x(2)-[RKSEQNA]-x-[LIVM]-x(2)-[LIVMA]-x(5)-
[STAG]-x(2)-C-x(3)-[EQ]-[LIVM](2)-x(9,10)-C-[LV]-[DN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 65 in 65 different sequences
Number of true positive hits 65 in 65 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 16
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 80.25 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 16
Site [info] disulfide at position 21
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
65 sequences

AMC2_PIG(P22952), AMC_RABIT   (P82535), CX116_DANRE (B0R191), 
» more

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

CX111_DANRE (A0A0R4INB9), CXL14_HUMAN (O95715), CXL14_MOUSE (Q9WUQ5), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

GRO1_RABIT  (P30782), PLF4_RABIT  (P83470)

		
PDB
[Detailed view]
67 PDB

1F9P; 1F9Q; 1F9R; 1F9S; 1IKL; 1IKM; 1IL8; 1ILP; 1ILQ; 1LV9; 1MGS; 1MI2;
» more