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Entry: PS00472

General information about the entry

Entry name [info] SMALL_CYTOKINES_CC
Accession [info] PS00472
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-APR-2006 DATA UPDATE;
18-SEP-2019 INFO UPDATE.
PROSITE Doc. [info] PDOC00434

Name and characterization of the entry

Description [info] Small cytokines (intercrine/chemokine) C-C subfamily signature.
Pattern [info]
C-C-[LIFYTRQ]-x(5,8)-[LIR]-x(4)-[LIVMFA]-x(2)-[FYWECI]-x(5,8)-C-x(3,4)-
[SAG]-[LIVM](2)-[FL]-x(7,9)-C-[STAV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2019_08 which contains 560'823 sequence entries.


Total number of hits 90 in 90 different sequences
Number of true positive hits 90 in 90 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.54 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 2
Site [info] disulfide at position 11
Site [info] disulfide at position 17
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
90 sequences

CC4L_HUMAN  (Q8NHW4    ), CCL11_BOVIN (Q9TTS6    ), CCL11_CAVPO (P80325    ), 
CCL11_HORSE (Q9TTQ4    ), CCL11_HUMAN (P51671    ), CCL11_MACMU (Q8MIT7    ), 
CCL11_MOUSE (P48298    ), CCL11_RAT   (P97545    ), CCL12_MOUSE (Q62401    ), 
CCL13_CANLF (Q68Y88    ), CCL13_HUMAN (Q99616    ), CCL14_HUMAN (Q16627    ), 
CCL15_HUMAN (Q16663    ), CCL16_HUMAN (O15467    ), CCL17_CANLF (Q95N01    ), 
CCL17_FELCA (Q8I021    ), CCL17_HUMAN (Q92583    ), CCL17_MACMU (Q8HYP9    ), 
CCL18_HUMAN (P55774    ), CCL18_MACMU (Q8HYP8    ), CCL19_HUMAN (Q99731    ), 
CCL19_MOUSE (O70460    ), CCL1_HUMAN  (P22362    ), CCL1_MOUSE  (P10146    ), 
CCL20_BOVIN (Q8SQB1    ), CCL20_HUMAN (P78556    ), CCL20_MOUSE (O89093    ), 
CCL22_HUMAN (O00626    ), CCL22_MOUSE (O88430    ), CCL23_HUMAN (P55773    ), 
CCL23_MACMU (Q8HYP4    ), CCL24_MOUSE (Q9JKC0    ), CCL25_CANLF (Q68A93    ), 
CCL26_CANLF (Q64H35    ), CCL26_HUMAN (Q9Y258    ), CCL28_CANLF (Q68A91    ), 
CCL28_HUMAN (Q9NRJ3    ), CCL2_BOVIN  (P28291    ), CCL2_CANLF  (P52203    ), 
CCL2_CAVPO  (Q08782    ), CCL2_HORSE  (Q9TTQ3    ), CCL2_HUMAN  (P13500    ), 
CCL2_MACFA  (P61274    ), CCL2_MACMU  (P61275    ), CCL2_MOUSE  (P10148    ), 
CCL2_PIG    (P42831    ), CCL2_PONAB  (Q5RA36    ), CCL2_RABIT  (P28292    ), 
CCL2_RAT    (P14844    ), CCL3_BOVIN  (Q8SQA6    ), CCL3_CANLF  (Q68A92    ), 
CCL3_HUMAN  (P10147    ), CCL3_MACMU  (Q8HYQ3    ), CCL3_MOUSE  (P10855    ), 
CCL3_PANTR  (Q5I1Z0    ), CCL3_RAT    (P50229    ), CCL4_BOVIN  (Q17QA1    ), 
CCL4_CANLF  (Q68AZ0    ), CCL4_CHICK  (Q90826    ), CCL4_HUMAN  (P13236    ), 
CCL4_MACMU  (Q8HYQ2    ), CCL4_MOUSE  (P14097    ), CCL4_PIG    (Q711P4    ), 
CCL4_RABIT  (P46632    ), CCL4_RAT    (P50230    ), CCL5_BOVIN  (O97919    ), 
CCL5_CANLF  (Q8HYS0    ), CCL5_CAVPO  (P97272    ), CCL5_FELCA  (Q8SQ40    ), 
CCL5_HORSE  (Q8MKD0    ), CCL5_HUMAN  (P13501    ), CCL5_MACMU  (Q8HYQ1    ), 
CCL5_MOUSE  (P30882    ), CCL5_RAT    (P50231    ), CCL5_SIGHI  (Q91ZL1    ), 
CCL6_MOUSE  (P27784    ), CCL6_RAT    (Q68FP3    ), CCL7_HUMAN  (P80098    ), 
CCL7_MOUSE  (Q03366    ), CCL7_RAT    (Q9QXY8    ), CCL8_BOVIN  (Q09141    ), 
CCL8_CANLF  (Q68AY9    ), CCL8_HUMAN  (P80075    ), CCL8_MOUSE  (Q9Z121    ), 
CCL8_PIG    (P49873    ), CCL9_MOUSE  (P51670    ), CL3L1_HUMAN (P16619    ), 
MCPB_BOVIN  (P80343    ), REG1_BOVIN  (P82943    ), VMI2_HHV8P  (Q98157    )
» more

UniProtKB/Swiss-Prot
False negative sequences
14 sequences

CC21A_MOUSE (P84444    ), CC21B_MOUSE (P86792    ), CC21C_MOUSE (P86793    ), 
CCL20_RAT   (P97884    ), CCL21_HUMAN (O00585    ), CCL21_MACMU (Q8HYP5    ), 
CCL24_CANLF (Q68Y86    ), CCL24_HUMAN (O00175    ), CCL25_HUMAN (O15444    ), 
CCL25_MOUSE (O35903    ), CCL25_PIG   (Q4PR21    ), CCL27_HUMAN (Q9Y4X3    ), 
CCL27_MOUSE (Q9Z1X0    ), CCL28_MOUSE (Q9JIL2    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

CCL5_PIG    (Q29288    )

		
PDB
[Detailed view]
82 PDB

1B3A; 1B50; 1B53; 1BO0; 1CM9; 1DOK; 1DOL; 1DOM; 1DON; 1EL0; 1EOT; 1ESR; 1G2S; 1G2T; 1G91; 1HA6; 1HFG; 1HFN; 1HHV; 1HRJ; 1HUM; 1HUN; 1M8A; 1ML0; 1NCV; 1NR2; 1NR4; 1RTN; 1RTO; 1U4L; 1U4M; 1U4P; 1U4R; 1VMP; 2BDN; 2EOT; 2FFK; 2FHT; 2FIN; 2FJ2; 2HCC; 2HCI; 2JYO; 2L9H; 2MP1; 2MPM; 2NZ1; 2Q8R; 2Q8T; 2RA4; 2VXW; 2X69; 2X6G; 2X6L; 3FPU; 3IFD; 3KBX; 3TN2; 4DN4; 4MHE; 4OIJ; 4OIK; 4R8I; 4RA8; 4RWS; 4ZK9; 4ZKC; 4ZLT; 5CMD; 5COR; 5COY; 5D65; 5DNF; 5L2U; 5LTL; 5UIW; 5UR7; 5WK3; 5YAM; 6C6D; 6CWS; 6FGP
» more

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