PROSITE logo

PROSITE entry PS00472


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] SMALL_CYTOKINES_CC
Accession [info] PS00472
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00434

Name and characterization of the entry

Description [info] Small cytokines (intercrine/chemokine) C-C subfamily signature.
Pattern [info]
C-C-[LIFYTRQ]-x(5,8)-[LIR]-x(4)-[LIVMFA]-x(2)-[FYWECI]-x(5,8)-C-x(3,4)-
[SAG]-[LIVM](2)-[FL]-x(7,9)-C-[STAV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 92 in 92 different sequences
Number of true positive hits 92 in 92 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 86.79 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 2
Site [info] disulfide at position 11
Site [info] disulfide at position 17
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
92 sequences

CC4L_HUMAN  (Q8NHW4), CCL11_BOVIN (Q9TTS6), CCL11_CAVPO (P80325), 
CCL11_HORSE (Q9TTQ4), CCL11_HUMAN (P51671), CCL11_MACMU (Q8MIT7), 
CCL11_MOUSE (P48298), CCL11_RAT   (P97545), CCL12_MOUSE (Q62401), 
CCL13_CANLF (Q68Y88), CCL13_HUMAN (Q99616), CCL14_HUMAN (Q16627), 
CCL15_HUMAN (Q16663), CCL16_HUMAN (O15467), CCL17_CANLF (Q95N01), 
CCL17_FELCA (Q8I021), CCL17_HUMAN (Q92583), CCL17_MACMU (Q8HYP9), 
CCL17_MOUSE (Q9WUZ6), CCL17_RAT   (Q9ERE0), CCL18_HUMAN (P55774), 
CCL18_MACMU (Q8HYP8), CCL19_HUMAN (Q99731), CCL19_MOUSE (O70460), 
CCL1_HUMAN  (P22362), CCL1_MOUSE  (P10146), CCL20_BOVIN (Q8SQB1), 
CCL20_HUMAN (P78556), CCL20_MOUSE (O89093), CCL22_HUMAN (O00626), 
CCL22_MOUSE (O88430), CCL23_HUMAN (P55773), CCL23_MACMU (Q8HYP4), 
CCL24_MOUSE (Q9JKC0), CCL25_CANLF (Q68A93), CCL26_CANLF (Q64H35), 
CCL26_HUMAN (Q9Y258), CCL28_CANLF (Q68A91), CCL28_HUMAN (Q9NRJ3), 
CCL2_BOVIN  (P28291), CCL2_CANLF  (P52203), CCL2_CAVPO  (Q08782), 
CCL2_HORSE  (Q9TTQ3), CCL2_HUMAN  (P13500), CCL2_MACFA  (P61274), 
CCL2_MACMU  (P61275), CCL2_MOUSE  (P10148), CCL2_PIG(P42831), 
CCL2_PONAB  (Q5RA36), CCL2_RABIT  (P28292), CCL2_RAT(P14844), 
CCL3_BOVIN  (Q8SQA6), CCL3_CANLF  (Q68A92), CCL3_HUMAN  (P10147), 
CCL3_MACMU  (Q8HYQ3), CCL3_MOUSE  (P10855), CCL3_PANTR  (Q5I1Z0), 
CCL3_RAT(P50229), CCL4_BOVIN  (Q17QA1), CCL4_CANLF  (Q68AZ0), 
CCL4_CHICK  (Q90826), CCL4_HUMAN  (P13236), CCL4_MACMU  (Q8HYQ2), 
CCL4_MOUSE  (P14097), CCL4_PIG(Q711P4), CCL4_RABIT  (P46632), 
CCL4_RAT(P50230), CCL5_BOVIN  (O97919), CCL5_CANLF  (Q8HYS0), 
CCL5_CAVPO  (P97272), CCL5_FELCA  (Q8SQ40), CCL5_HORSE  (Q8MKD0), 
CCL5_HUMAN  (P13501), CCL5_MACMU  (Q8HYQ1), CCL5_MOUSE  (P30882), 
CCL5_RAT(P50231), CCL5_SIGHI  (Q91ZL1), CCL6_MOUSE  (P27784), 
CCL6_RAT(Q68FP3), CCL7_HUMAN  (P80098), CCL7_MOUSE  (Q03366), 
CCL7_RAT(Q9QXY8), CCL8_BOVIN  (Q09141), CCL8_CANLF  (Q68AY9), 
CCL8_HUMAN  (P80075), CCL8_MOUSE  (Q9Z121), CCL8_PIG(P49873), 
CCL9_MOUSE  (P51670), CL3L1_HUMAN (P16619), MCPB_BOVIN  (P80343), 
REG1_BOVIN  (P82943), VMI2_HHV8P  (Q98157)
» more

UniProtKB/Swiss-Prot
False negative sequences
14 sequences

CC21A_MOUSE (P84444), CC21B_MOUSE (P86792), CC21C_MOUSE (P86793), 
CCL20_RAT   (P97884), CCL21_HUMAN (O00585), CCL21_MACMU (Q8HYP5), 
CCL24_CANLF (Q68Y86), CCL24_HUMAN (O00175), CCL25_HUMAN (O15444), 
CCL25_MOUSE (O35903), CCL25_PIG   (Q4PR21), CCL27_HUMAN (Q9Y4X3), 
CCL27_MOUSE (Q9Z1X0), CCL28_MOUSE (Q9JIL2)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

CCL5_PIG(Q29288)

		
PDB
[Detailed view]
113 PDB

1B3A; 1B50; 1B53; 1BO0; 1CM9; 1DOK; 1DOL; 1DOM; 1DON; 1EL0; 1EOT; 1ESR; 1G2S; 1G2T; 1G91; 1HA6; 1HFG; 1HFN; 1HHV; 1HRJ; 1HUM; 1HUN; 1M8A; 1ML0; 1NCV; 1NR2; 1NR4; 1RTN; 1RTO; 1U4L; 1U4M; 1U4P; 1U4R; 1VMP; 2BDN; 2EOT; 2FFK; 2FHT; 2FIN; 2FJ2; 2HCC; 2HCI; 2JYO; 2L9H; 2MP1; 2MPM; 2NZ1; 2Q8R; 2Q8T; 2RA4; 2VXW; 2X69; 2X6G; 2X6L; 3FPU; 3H44; 3IFD; 3KBX; 3TN2; 4DN4; 4MHE; 4OIJ; 4OIK; 4R8I; 4RA8; 4RAL; 4RWS; 4ZK9; 4ZKB; 4ZKC; 4ZLT; 5CMD; 5COR; 5COY; 5D65; 5DNF; 5L2U; 5LTL; 5UIW; 5UR7; 5WK3; 5YAM; 6AEZ; 6C6D; 6CWS; 6FGP; 6STK; 6WWZ; 7F1Q; 7F1R; 7F1T; 7O7F; 7S4N; 7S58; 7S59; 7S5A; 7SCS; 7SCT; 7SCU; 7SCV; 7SO0; 7STA; 7T1E; 7VL9; 7VLA; 7XA3; 8FJ0; 8FJ2; 8FK6; 8FK8; 8FK9; 8SKK; 8U1U
» more