PROSITE entry PS00477
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS00477 |
| Entry name [info] | ALPHA_2_MACROGLOBULIN |
| Accession [info] | PS00477 |
| Entry type [info] | PATTERN |
| Date [info] |
01-MAY-1991 CREATED;
01-MAY-1991 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00440 |
Name and characterization of the entry
| Description [info] | Alpha-2-macroglobulin family thiolester region signature. |
| Pattern [info] |
[PG]-x-[GS]-C-[GA]-E-[EQ]-x-[LIVM]. |
Numerical results [info]
| Total number of hits | 51 in 51 different sequences |
| Number of true positive hits | 45 in 45 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 6 in 6 different sequences |
| Number of false negative sequences | 5 |
| Number of 'partial' sequences | 5 |
| Precision (true positives / (true positives + false positives)) | 88.24 % |
| Recall (true positives / (true positives + false negatives)) | 90.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Site [info] | thiolester at position 4 |
| Site [info] | thiolester at position 7 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
45 sequences
A1I3_RAT(P14046), A1M_RAT (Q63041), A2MG_BOVIN (Q7SIH1), A2MG_HUMAN (P01023), A2MG_MOUSE (Q6GQT1), A2MG_PONAB (Q5R4N8), A2MG_RAT(P06238), A2ML1_HUMAN (A8K2U0), A2M_HOMAM (P20737), A2M_OCTVU (P30800), A2M_PACLE (P20738), CD109_HUMAN (Q6YHK3), CD109_MOUSE (Q8R422), CO3_BOVIN (Q2UVX4), CO3_CAVPO (P12387), CO3_EPTBU (P98094), CO3_HUMAN (P01024), CO3_LETCA (Q00685), CO3_MOUSE (P01027), CO3_NAJNA (Q01833), CO3_ONCMY (P98093), CO3_PIG (P01025), CO3_RABIT (P12247), CO3_RAT (P01026), CO4A_HUMAN (P0C0L4), CO4B_HUMAN (P0C0L5), CO4B_MOUSE (P01029), CO4_BOVIN (P01030), CO4_RAT (P08649), CPMD8_HUMAN (Q8IZJ3), MUG1_MOUSE (P28665), MUG1_RAT(Q03626), MUG2_MOUSE (P28666), MUG2_RAT(Q6IE52), OVOS_ANAPL (P20739), OVOS_MOUSE (Q3UU35), PZP_HUMAN (P20742), PZP_MOUSE (Q61838), TEPR1_ANOGA (C9XI66), TEPS1_ANOGA (Q9GYW4), TEPS3_ANOGA (C9XI63), VCO31_AUSSU (Q0ZZJ6), VCO3_CROAD (J3S836), VCO3_NAJKA (Q91132), VCO3_OPHHA (I2C090)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
5 sequences
CO5_HUMAN (P01031), CO5_MOUSE (P06684), OVOS1_HUMAN (Q6IE37), OVOS_CHICK (P20740), VCO32_AUSSU (A0RZC6)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
5 sequences
CO3_XENLA (P23667), CO4_CAVPO (P19069), CO5_BOVIN (P12082), CO5_PIG (P01032), CO5_RAT (P08650)» more |
| UniProtKB/Swiss-Prot False positive sequences |
6 sequences
GALT5_HUMAN (Q7Z7M9), GALT5_MOUSE (Q8C102), GALT5_RAT (O88422), ISPE_CHLAB (Q5L568), ISPE_CHLCV (Q821X0), OACYL_MOUSE (Q8BML2)» more |
| PDB [Detailed view] |
62 PDB
1HZF; 2A73; 2I07; 2ICF; 2PN5; 2WII; 2WIN; 2XWB; 2XWJ; 3G6J; 3L5N; 3PRX; 3PVM; 4D94; 4LNV; 5FO7; 5FO8; 5FO9; 5FOA; 5FOB; 5JPM; 5JPN; 5JTW; 5O32; 5O35; 6EHG; 6RMT; 6RMU; 6RUR; 6RUV; 6TAV; 6YO6; 6YSQ; 7AKK; 7BAG; 7NOZ; 7O7L; 7O7M; 7O7N; 7O7O; 7O7P; 7O7Q; 7O7R; 7O7S; 7Q1Y; 7Q5Z; 7Q60; 7Q61; 7Q62; 7QIV; 7TV9; 7VON; 7VOO; 7ZGK; 8AYH; 8CEM; 8ENU; 8EOK; 8OQ3; 8OVB; 8UH2; 8UIN » more |