Entry: PS00478

General information about the entry

Entry name [info] LIM_DOMAIN_1
Accession [info] PS00478
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED; 01-DEC-2004 DATA UPDATE; 12-SEP-2018 INFO UPDATE.
PROSITE Doc. [info] PDOC00382

Name and characterization of the entry

Description [info] LIM zinc-binding domain signature.
Pattern [info] 
C-x(2)-C-x(15,21)-[FYWHPCR]-H-x(2)-[CH]-x(2)-C-x(2)-C-x(3)-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2018_08 which contains 558'125 sequence entries.


Total number of hits 777 in 391 different sequences
Number of true positive hits 776 in 390 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 7
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.87 %
Recall (true positives / (true positives + false negatives)) 99.11 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Site [info] zinc at position 1
Site [info] zinc at position 3
Site [info] zinc at position 6
Site [info] zinc at position 8
Site [info] zinc at position 10
Site [info] zinc at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 390 sequences 

ABLM1_HUMAN (O14639    ), ABLM1_MOUSE (Q8K4G5    ), ABLM2_HUMAN (Q6H8Q1    ), 

ABLM2_MOUSE (Q8BL65    ), ABLM2_RAT   (Q6KC51    ), ABLM3_HUMAN (O94929    ), 
ABLM3_MOUSE (Q69ZX8    ), AJUBA_BOVIN (E1BKA3    ), AJUBA_DROME (Q9VY77    ), 
AJUBA_HUMAN (Q96IF1    ), AJUBA_MOUSE (Q91XC0    ), AJUBA_RAT   (Q5U2Z2    ), 
APTE_DROME  (P29673    ), AWH_DROME   (Q8IRC7    ), CRIP1_BOVIN (Q56K04    ), 
CRIP1_HUMAN (P50238    ), CRIP1_MOUSE (P63254    ), CRIP1_RAT   (P63255    ), 
CRIP2_BOVIN (Q0VFX8    ), CRIP2_HUMAN (P52943    ), CRIP2_MOUSE (Q9DCT8    ), 
CRIP2_PONAB (Q5R7Y1    ), CRIP2_RAT   (P36201    ), CRIP3_HUMAN (Q6Q6R5    ), 
CRIP3_MOUSE (Q6Q6R3    ), CSRP1_BOVIN (Q3MHY1    ), CSRP1_CHICK (P67966    ), 
CSRP1_COTJA (P67967    ), CSRP1_HUMAN (P21291    ), CSRP1_MOUSE (P97315    ), 
CSRP1_PONAB (Q5RCT4    ), CSRP1_RAT   (P47875    ), CSRP2_BOVIN (Q32LE9    ), 
CSRP2_CHICK (P50460    ), CSRP2_COTJA (Q05158    ), CSRP2_HUMAN (Q16527    ), 
CSRP2_MOUSE (P97314    ), CSRP2_RAT   (Q62908    ), CSRP3_BOVIN (Q4U0T9    ), 
CSRP3_HUMAN (P50461    ), CSRP3_MOUSE (P50462    ), CSRP3_RAT   (P50463    ), 
DA1_ARATH   (P0C7Q8    ), DAR1_ARATH  (Q8W4F0    ), DAR2_ARATH  (Q0WSN2    ), 
DAR4_ARATH  (Q9FKN7    ), DAR5_ARATH  (Q84WJ0    ), DAR6_ARATH  (Q9FJX8    ), 
DAR7_ARATH  (Q9FJX9    ), ESN_DROME   (Q9U1I1    ), ESN_DROPS   (Q292U5    ), 
FBLI1_BOVIN (Q1JQB5    ), FBLI1_HUMAN (Q8WUP2    ), FBLI1_MOUSE (Q71FD7    ), 
FBLI1_PONAB (Q5REN1    ), FHL1_HUMAN  (Q13642    ), FHL1_MOUSE  (P97447    ), 
FHL1_RAT    (Q9WUH4    ), FHL2_BOVIN  (Q2KI95    ), FHL2_HUMAN  (Q14192    ), 
FHL2_MOUSE  (O70433    ), FHL2_RAT    (O35115    ), FHL3_BOVIN  (Q3ZBI6    ), 
FHL3_HUMAN  (Q13643    ), FHL3_MOUSE  (Q9R059    ), FHL5_BOVIN  (Q2YDK0    ), 
FHL5_HUMAN  (Q5TD97    ), FHL5_MACFA  (Q4R7A4    ), FHL5_MOUSE  (Q9WTX7    ), 
FHL5_RAT    (Q6AXT1    ), HIL_DROME   (Q0E908    ), HM14_CAEEL  (P20271    ), 
ISL1_CHICK  (P50211    ), ISL1_DANRE  (P53405    ), ISL1_HUMAN  (P61371    ), 
ISL1_MESAU  (P61373    ), ISL1_MOUSE  (P61372    ), ISL1_RAT    (P61374    ), 
ISL2A_DANRE (P53406    ), ISL2A_ONCTS (P53408    ), ISL2B_DANRE (P53407    ), 
ISL2B_ONCTS (P50212    ), ISL2_CHICK  (P53410    ), ISL2_HUMAN  (Q96A47    ), 
ISL2_MOUSE  (Q9CXV0    ), ISL2_RAT    (P50480    ), ISL3_ONCTS  (P53409    ), 
LASP1_BOVIN (Q3B7M5    ), LASP1_DROME (Q8I7C3    ), LASP1_HUMAN (Q14847    ), 
LASP1_MOUSE (Q61792    ), LASP1_PONAB (Q5R5W0    ), LASP1_RABIT (O77506    ), 
LASP1_RAT   (Q99MZ8    ), LDB3_HUMAN  (O75112    ), LDB3_MOUSE  (Q9JKS4    ), 
LHX1_CHICK  (P53411    ), LHX1_DANRE  (Q90476    ), LHX1_HUMAN  (P48742    ), 
LHX1_MESAU  (P63008    ), LHX1_MOUSE  (P63006    ), LHX1_PANTR  (Q5IS44    ), 
LHX1_RAT    (P63007    ), LHX1_SAIBB  (Q5IS89    ), LHX1_XENLA  (P29674    ), 
LHX2_HUMAN  (P50458    ), LHX2_MOUSE  (Q9Z0S2    ), LHX2_RAT    (P36198    ), 
LHX3_CHICK  (P53412    ), LHX3_DANRE  (Q90421    ), LHX3_HUMAN  (Q9UBR4    ), 
LHX3_MOUSE  (P50481    ), LHX3_PIG    (O97581    ), LHX3_XENLA  (P36200    ), 
LHX4_HUMAN  (Q969G2    ), LHX4_MOUSE  (P53776    ), LHX5_DANRE  (P52889    ), 
LHX5_HUMAN  (Q9H2C1    ), LHX5_MOUSE  (P61375    ), LHX5_RAT    (P61376    ), 
LHX5_XENLA  (P37137    ), LHX6_HUMAN  (Q9UPM6    ), LHX6_MOUSE  (Q9R1R0    ), 
LHX8_HUMAN  (Q68G74    ), LHX8_MOUSE  (O35652    ), LHX9_ASTFA  (A2I8Z7    ), 
LHX9_BOVIN  (A0JNI8    ), LHX9_CHICK  (Q90881    ), LHX9_DANRE  (Q1LWV4    ), 
LHX9_HUMAN  (Q9NQ69    ), LHX9_MOUSE  (Q9WUH2    ), LHX9_RAT    (Q80W90    ), 
LHX9_RUGRU  (A2PZF9    ), LHX9_XENLA  (Q68EY3    ), LIMA1_HUMAN (Q9UHB6    ), 
LIMA1_MOUSE (Q9ERG0    ), LIMA1_PIG   (B0KYV5    ), LIMA_DICDI  (Q54QR1    ), 
LIMB_DICDI  (Q54NW4    ), LIMC1_HUMAN (Q9UPQ0    ), LIMC1_MOUSE (Q3UH68    ), 
LIMC1_XENLA (Q3KQW7    ), LIMCH_DICDI (Q55GV9    ), LIMC_DICDI  (Q9BIW5    ), 
LIMD1_BOVIN (G5E5X0    ), LIMD1_HUMAN (Q9UGP4    ), LIMD1_MOUSE (Q9QXD8    ), 
LIMD1_RAT   (B5DEH0    ), LIMD1_XENLA (Q06BR1    ), LIMD1_XENTR (B7ZUL2    ), 
LIMD2_BOVIN (Q1LZA7    ), LIMD2_HUMAN (Q9BT23    ), LIMD2_MOUSE (Q8BGB5    ), 
LIMD2_RAT   (Q4KM31    ), LIMD_DICDI  (Q9BIW4    ), LIME_DICDI  (O60952    ), 
LIMF_DICDI  (Q86I44    ), LIMG_DICDI  (Q55DS4    ), LIMK1_CHICK (Q8QFP8    ), 
LIMK1_DROME (Q8IR79    ), LIMK1_HUMAN (P53667    ), LIMK1_MOUSE (P53668    ), 
LIMK1_RAT   (P53669    ), LIMK1_XENLA (O42565    ), LIMK2_BOVIN (Q32L23    ), 
LIMK2_CHICK (P53666    ), LIMK2_HUMAN (P53671    ), LIMK2_MOUSE (O54785    ), 
LIMK2_RAT   (P53670    ), LIMKA_DICDI (Q54L00    ), LIMKB_DICDI (P0CD62    ), 
LIMS1_HUMAN (P48059    ), LIMS1_MOUSE (Q99JW4    ), LIMS2_BOVIN (Q2KJ33    ), 
LIMS2_HUMAN (Q7Z4I7    ), LIMS2_MOUSE (Q91XD2    ), LIMS3_HUMAN (P0CW19    ), 
LIMS4_HUMAN (P0CW20    ), LIN11_CAEEL (P20154    ), LMCD1_BOVIN (Q17QE2    ), 
LMCD1_HUMAN (Q9NZU5    ), LMCD1_MOUSE (Q8VEE1    ), LMCD1_PIG   (Q5PXT2    ), 
LMO3_BOVIN  (Q2KIA3    ), LMO3_DANRE  (Q503U0    ), LMO3_HUMAN  (Q8TAP4    ), 
LMO3_MOUSE  (Q8BZL8    ), LMO3_PONAB  (Q5RBW7    ), LMO3_RAT    (Q99MB5    ), 
LMO3_XENLA  (Q9YH16    ), LMO41_XENTR (Q5FVB2    ), LMO42_XENTR (Q6DJ06    ), 
LMO4A_XENLA (Q8AW92    ), LMO4B_XENLA (Q801P0    ), LMO4_BOVIN  (Q3SWZ8    ), 
LMO4_HUMAN  (P61968    ), LMO4_MOUSE  (P61969    ), LMO7_HUMAN  (Q8WWI1    ), 
LMX1A_HUMAN (Q8TE12    ), LMX1A_MESAU (Q04650    ), LMX1A_MOUSE (Q9JKU8    ), 
LMX1B_CHICK (P53413    ), LMX1B_HUMAN (O60663    ), LMX1B_MESAU (Q60564    ), 
LMX1B_MOUSE (O88609    ), LMX1B_XENLA (Q8UVR3    ), LNEBL_MOUSE (Q9DC07    ), 
LPP_CHICK   (Q5F464    ), LPP_HUMAN   (Q93052    ), LPP_MOUSE   (Q8BFW7    ), 
LPP_RAT     (Q5XI07    ), LPXN_HUMAN  (O60711    ), LPXN_MOUSE  (Q99N69    ), 
LPXN_RABIT  (Q9N261    ), LRG1_YEAST  (P35688    ), MCA2B_DANRE (F1RA39    ), 
MCA3A_DANRE (F1QH17    ), MCA3B_DANRE (F1QWK4    ), MEC3_CAEBR  (P34764    ), 
MEC3_CAEEL  (P09088    ), MEC3_CAERE  (P34765    ), MICA1_BOVIN (F1MH07    ), 
MICA1_DANRE (E7F9T0    ), MICA1_HUMAN (Q8TDZ2    ), MICA1_MOUSE (Q8VDP3    ), 
MICA1_RAT   (D3ZBP4    ), MICA2_BOVIN (F1MF74    ), MICA2_HUMAN (O94851    ), 
MICA2_MOUSE (Q8BML1    ), MICA2_RAT   (D4A1F2    ), MICA2_XENTR (F6QZ15    ), 
MICA3_BOVIN (G3MWR8    ), MICA3_HUMAN (Q7RTP6    ), MICA3_MOUSE (Q8CJ19    ), 
MILK1_BOVIN (E1BBG2    ), MILK1_HUMAN (Q8N3F8    ), MILK1_MOUSE (Q8BGT6    ), 
MILK1_RAT   (D3ZQL6    ), MILK2_HUMAN (Q8IY33    ), MILK2_MOUSE (Q3TN34    ), 
MILK2_RAT   (D3ZEN0    ), MLP1_DROME  (P53777    ), MLP2_DROME  (Q24400    ), 
NRAP_HUMAN  (Q86VF7    ), NRAP_MOUSE  (Q80XB4    ), PAXB_DICDI  (Q8MML5    ), 
PAXI_CHICK  (P49024    ), PAXI_HUMAN  (P49023    ), PAXI_MOUSE  (Q8VI36    ), 
PAXI_PONAB  (Q5R7I1    ), PAXI_RAT    (Q66H76    ), PDLI1_BOVIN (Q5E9E1    ), 
PDLI1_HUMAN (O00151    ), PDLI1_MOUSE (O70400    ), PDLI1_RAT   (P52944    ), 
PDLI2_BOVIN (Q3T0C8    ), PDLI2_HUMAN (Q96JY6    ), PDLI2_MACFA (Q9GKU1    ), 
PDLI2_MOUSE (Q8R1G6    ), PDLI2_RAT   (Q6AYD6    ), PDLI3_BOVIN (Q3SYZ8    ), 
PDLI3_CHICK (Q9PU47    ), PDLI3_HUMAN (Q53GG5    ), PDLI3_MOUSE (O70209    ), 
PDLI3_PIG   (Q6QGC0    ), PDLI3_RAT   (Q66HS7    ), PDLI3_XENLA (Q6GLJ6    ), 
PDLI4_BOVIN (Q3T005    ), PDLI4_CHICK (Q9PW72    ), PDLI4_HUMAN (P50479    ), 
PDLI4_MOUSE (P70271    ), PDLI4_RAT   (P36202    ), PDLI5_HUMAN (Q96HC4    ), 
PDLI5_MOUSE (Q8CI51    ), PDLI5_RAT   (Q62920    ), PDLI7_BOVIN (Q3SX40    ), 
PDLI7_CHICK (Q679P3    ), PDLI7_DANRE (Q6P7E4    ), PDLI7_HUMAN (Q9NR12    ), 
PDLI7_MOUSE (Q3TJD7    ), PDLI7_RAT   (Q9Z1Z9    ), PDLI7_XENLA (Q6INU3    ), 
PIN2_CAEEL  (Q19157    ), PLI2A_ARATH (O80839    ), PLI2B_ARATH (Q1ECF5    ), 
PLI2B_ORYSJ (Q7F9R9    ), PLI2C_ARATH (Q500W4    ), PRC3A_XENLA (A8WH69    ), 
PRC3B_XENLA (A0A1L8F1M4), PRI1A_XENLA (Q90Z06    ), PRI1B_XENLA (Q90WV2    ), 
PRIC1_AEDAE (Q174I2    ), PRIC1_ANOGA (Q7QJT4    ), PRIC1_DROME (A1Z6W3    ), 
PRIC1_DROPS (Q292U2    ), PRIC1_HUMAN (Q96MT3    ), PRIC1_MOUSE (Q3U5C7    ), 
PRIC1_RAT   (Q71QF9    ), PRIC1_XENTR (Q28FG2    ), PRIC2_HUMAN (Q7Z3G6    ), 
PRIC2_MOUSE (Q80Y24    ), PRIC3_HUMAN (O43900    ), PRIC3_MOUSE (Q80VL3    ), 
PRIC4_HUMAN (Q2TBC4    ), PXL1_CAEEL  (Q09476    ), PXL1_YEAST  (P36166    ), 
RBTN1_BOVIN (Q0P5B3    ), RBTN1_DANRE (Q8JFQ2    ), RBTN1_HUMAN (P25800    ), 
RBTN1_MOUSE (Q924W9    ), RBTN1_XENLA (Q3B8H4    ), RBTN2_BOVIN (Q1LZ94    ), 
RBTN2_DANRE (Q9PTJ3    ), RBTN2_HUMAN (P25791    ), RBTN2_MOUSE (P25801    ), 
RBTN2_XENLA (Q90XH3    ), RBTN2_XENTR (Q5M8V8    ), RGA1_SCHPO  (O43052    ), 
RGA1_YEAST  (P39083    ), RGA2_YEAST  (Q06407    ), RGA3_SCHPO  (O14014    ), 
RGA4_SCHPO  (O74360    ), SCEL_HUMAN  (O95171    ), SCEL_MOUSE  (Q9EQG3    ), 
SF3_HELAN   (P29675    ), TES_AOTNA   (Q07DW1    ), TES_ATEAB   (Q00PK1    ), 
TES_ATEGE   (Q09YL5    ), TES_BOVIN   (Q2YDE9    ), TES_CALJA   (Q2QLG8    ), 
TES_CANLF   (A0M8U6    ), TES_CHICK   (Q90YH9    ), TES_CHLAE   (Q2IBA3    ), 
TES_COLGU   (Q07DZ4    ), TES_DASNO   (Q07E51    ), TES_EULMM   (Q2IBH0    ), 
TES_FELCA   (A0M8S5    ), TES_HORSE   (Q2QLB2    ), TES_HUMAN   (Q9UGI8    ), 
TES_LOXAF   (Q108U9    ), TES_MICMU   (Q2QL92    ), TES_MONDO   (Q2QLA1    ), 
TES_MOUSE   (P47226    ), TES_MUNMU   (Q09YK3    ), TES_MUNRE   (Q07DX3    ), 
TES_MUSPF   (Q07E27    ), TES_NEONE   (Q07E40    ), TES_NOMLE   (Q07DY3    ), 
TES_OTOGA   (Q2QLH9    ), TES_PANTR   (Q2QLF4    ), TES_PAPAN   (A0M8R4    ), 
TES_PIG     (Q2QLE3    ), TES_PLEMO   (Q2QLC3    ), TES_PONAB   (Q5RC52    ), 
TES_RABIT   (Q09YN8    ), TES_RAT     (Q2LAP6    ), TES_RHIFE   (Q2IBC3    ), 
TES_SAIBB   (Q09YI0    ), TES_SHEEP   (Q09YJ2    ), TES_XENLA   (Q7ZXE9    ), 
TES_XENTR   (Q6DIR5    ), TGFI1_BOVIN (Q3MHZ4    ), TGFI1_HUMAN (O43294    ), 
TGFI1_MOUSE (Q62219    ), TGFI1_RAT   (Q99PD6    ), TGFI1_XENLA (Q2TCH4    ), 
TRIP6_BOVIN (Q3SX26    ), TRIP6_HUMAN (Q15654    ), TRIP6_MOUSE (Q9Z1Y4    ), 
TTX3_CAEEL  (G5EE86    ), UNC97_CAEEL (P50464    ), WLI2A_ARATH (O04193    ), 
WLI2B_ARATH (Q9M047    ), WLIM1_ARATH (Q94JX5    ), WTIP_DANRE  (A8DZE6    ), 
WTIP_HUMAN  (A6NIX2    ), WTIP_MOUSE  (Q7TQJ8    ), WTIP_XENLA  (A9LS46    ), 
XIRP2_MOUSE (Q4U4S6    ), Y6787_DICDI (Q55BI0    ), YOCC_SCHPO  (O74398    ), 
ZASP_DROME  (A1ZA47    ), ZN185_HUMAN (O15231    ), ZN185_MOUSE (Q62394    ), 
ZYX_CAEEL   (Q9U3F4    ), ZYX_CHICK   (Q04584    ), ZYX_HUMAN   (Q15942    ), 
ZYX_MOUSE   (Q62523    ), ZYX_XENLA   (A5H447    ), ZYX_XENTR   (Q0VA45    )
» more

UniProtKB/Swiss-Prot
False negative sequences		 7 sequences 

ADCE_DICDI  (Q55GN8    ), HEL2_SCHPO  (Q76PD2    ), HEL2_YEAST  (Q05580    ), 

LASP1_CAEEL (P34416    ), LHX3_HALRO  (Q25132    ), MICAL_DROME (Q86BA1    ), 
Y2098_DICDI (Q55A66    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

LASP1_PIG   (P80171    )


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
YEMC_SCHPO  (O14033    )


				
	

	

		PDB
[Detailed view]		
		
			62 PDB
			


			1A7I; 1B8T; 1CTL; 1CXX; 1G47; 1IBI; 1IML; 1J2O; 1M3V; 1NYP; 1QLI; 1RUT; 
			
				1U5S; 1V6G; 1WIG; 1WYH; 1X3H; 1X4K; 1X4L; 1X61; 1X62; 1X63; 1X64; 1X68; 
				1X6A; 2CO8; 2COR; 2CU8; 2CUP; 2CUQ; 2CUR; 2D8X; 2D8Y; 2D8Z; 2DFY; 2DJ7; 
				2DLO; 2EGQ; 2EHE; 2JTN; 2KBX; 2L4Z; 2L6Y; 2L6Z; 2LXD; 2LZU; 2MBV; 2MIU; 
				2O10; 2O13; 2RGT; 2XJY; 2XJZ; 2XQN; 2YPA; 3F6Q; 3IXE; 3MMK; 4HI8; 4HI9; 
				4JCJ; 4KFZ
			
			

			» more

				
	





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