PROSITE logo

PROSITE entry PS00478


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] LIM_DOMAIN_1
Accession [info] PS00478
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00382

Name and characterization of the entry

Description [info] LIM zinc-binding domain signature.
Pattern [info] 
C-x(2)-C-x(15,21)-[FYWHPCR]-H-x(2)-[CH]-x(2)-C-x(2)-C-x(3)-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 792 in 400 different sequences
Number of true positive hits 790 in 398 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 7
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.75 %
Recall (true positives / (true positives + false negatives)) 99.12 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Site [info] zinc at position 1
Site [info] zinc at position 3
Site [info] zinc at position 6
Site [info] zinc at position 8
Site [info] zinc at position 10
Site [info] zinc at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 398 sequences 

ABLM1_HUMAN (O14639), ABLM1_MOUSE (Q8K4G5), ABLM2_HUMAN (Q6H8Q1), 

ABLM2_MOUSE (Q8BL65), ABLM2_RAT   (Q6KC51), ABLM3_HUMAN (O94929), 
ABLM3_MOUSE (Q69ZX8), AJUBA_BOVIN (E1BKA3), AJUBA_DROME (Q9VY77), 
AJUBA_HUMAN (Q96IF1), AJUBA_MOUSE (Q91XC0), AJUBA_RAT   (Q5U2Z2), 
APTE_DROME  (P29673), AWH_DROME   (Q8IRC7), CRIP1_BOVIN (Q56K04), 
CRIP1_HUMAN (P50238), CRIP1_MOUSE (P63254), CRIP1_RAT   (P63255), 
CRIP2_BOVIN (Q0VFX8), CRIP2_HUMAN (P52943), CRIP2_MOUSE (Q9DCT8), 
CRIP2_PONAB (Q5R7Y1), CRIP2_RAT   (P36201), CRIP3_HUMAN (Q6Q6R5), 
CRIP3_MOUSE (Q6Q6R3), CSRP1_BOVIN (Q3MHY1), CSRP1_CHICK (P67966), 
CSRP1_COTJA (P67967), CSRP1_HUMAN (P21291), CSRP1_MOUSE (P97315), 
CSRP1_PONAB (Q5RCT4), CSRP1_RAT   (P47875), CSRP2_BOVIN (Q32LE9), 
CSRP2_CHICK (P50460), CSRP2_COTJA (Q05158), CSRP2_HUMAN (Q16527), 
CSRP2_MOUSE (P97314), CSRP2_RAT   (Q62908), CSRP3_BOVIN (Q4U0T9), 
CSRP3_HUMAN (P50461), CSRP3_MOUSE (P50462), CSRP3_RAT   (P50463), 
DA1_ARATH   (P0C7Q8), DAR1_ARATH  (Q8W4F0), DAR2_ARATH  (Q0WSN2), 
DAR4_ARATH  (Q9FKN7), DAR5_ARATH  (Q84WJ0), DAR6_ARATH  (Q9FJX8), 
DAR7_ARATH  (Q9FJX9), ESN_DROME   (Q9U1I1), ESN_DROPS   (Q292U5), 
FBLI1_BOVIN (Q1JQB5), FBLI1_HUMAN (Q8WUP2), FBLI1_MOUSE (Q71FD7), 
FBLI1_PONAB (Q5REN1), FHL1_HUMAN  (Q13642), FHL1_MOUSE  (P97447), 
FHL1_RAT(Q9WUH4), FHL2_BOVIN  (Q2KI95), FHL2_HUMAN  (Q14192), 
FHL2_MOUSE  (O70433), FHL2_RAT(O35115), FHL3_BOVIN  (Q3ZBI6), 
FHL3_HUMAN  (Q13643), FHL3_MOUSE  (Q9R059), FHL5_BOVIN  (Q2YDK0), 
FHL5_HUMAN  (Q5TD97), FHL5_MACFA  (Q4R7A4), FHL5_MOUSE  (Q9WTX7), 
FHL5_RAT(Q6AXT1), HDR3_ORYSJ  (Q10NJ6), HIL_DROME   (Q0E908), 
HM14_CAEEL  (P20271), ISL1_CHICK  (P50211), ISL1_DANRE  (P53405), 
ISL1_HUMAN  (P61371), ISL1_MESAU  (P61373), ISL1_MOUSE  (P61372), 
ISL1_RAT(P61374), ISL2A_DANRE (P53406), ISL2A_ONCTS (P53408), 
ISL2B_DANRE (P53407), ISL2B_ONCTS (P50212), ISL2_CHICK  (P53410), 
ISL2_HUMAN  (Q96A47), ISL2_MOUSE  (Q9CXV0), ISL2_RAT(P50480), 
ISL3_ONCTS  (P53409), KY_CAEEL(G5EF51), LASP1_BOVIN (Q3B7M5), 
LASP1_DROME (Q8I7C3), LASP1_HUMAN (Q14847), LASP1_MOUSE (Q61792), 
LASP1_PONAB (Q5R5W0), LASP1_RABIT (O77506), LASP1_RAT   (Q99MZ8), 
LDB3_HUMAN  (O75112), LDB3_MOUSE  (Q9JKS4), LHX1_CHICK  (P53411), 
LHX1_DANRE  (Q90476), LHX1_HUMAN  (P48742), LHX1_MESAU  (P63008), 
LHX1_MOUSE  (P63006), LHX1_PANTR  (Q5IS44), LHX1_RAT(P63007), 
LHX1_SAIBB  (Q5IS89), LHX1_XENLA  (P29674), LHX2_HUMAN  (P50458), 
LHX2_MOUSE  (Q9Z0S2), LHX2_RAT(P36198), LHX3_CHICK  (P53412), 
LHX3_DANRE  (Q90421), LHX3_HUMAN  (Q9UBR4), LHX3_MOUSE  (P50481), 
LHX3_PIG(O97581), LHX3_XENLA  (P36200), LHX4_HUMAN  (Q969G2), 
LHX4_MOUSE  (P53776), LHX5_DANRE  (P52889), LHX5_HUMAN  (Q9H2C1), 
LHX5_MOUSE  (P61375), LHX5_RAT(P61376), LHX5_XENLA  (P37137), 
LHX6_HUMAN  (Q9UPM6), LHX6_MOUSE  (Q9R1R0), LHX8_HUMAN  (Q68G74), 
LHX8_MOUSE  (O35652), LHX9_BOVIN  (A0JNI8), LHX9_CHICK  (Q90881), 
LHX9_DANRE  (Q1LWV4), LHX9_GLARU  (A2PZF9), LHX9_HUMAN  (Q9NQ69), 
LHX9_MOUSE  (Q9WUH2), LHX9_PSAFA  (A2I8Z7), LHX9_RAT(Q80W90), 
LHX9_XENLA  (Q68EY3), LIM4_CAEEL  (G5EEA1), LIM6_CAEEL  (Q21192), 
LIM7_CAEEL  (G5EC36), LIMA1_HUMAN (Q9UHB6), LIMA1_MOUSE (Q9ERG0), 
LIMA1_PIG   (B0KYV5), LIMA1_RAT   (F1LR10), LIMA_DICDI  (Q54QR1), 
LIMB_DICDI  (Q54NW4), LIMC1_HUMAN (Q9UPQ0), LIMC1_MOUSE (Q3UH68), 
LIMC1_XENLA (Q3KQW7), LIMCH_DICDI (Q55GV9), LIMC_DICDI  (Q9BIW5), 
LIMD1_BOVIN (G5E5X0), LIMD1_HUMAN (Q9UGP4), LIMD1_MOUSE (Q9QXD8), 
LIMD1_RAT   (B5DEH0), LIMD1_XENLA (Q06BR1), LIMD1_XENTR (B7ZUL2), 
LIMD2_BOVIN (Q1LZA7), LIMD2_HUMAN (Q9BT23), LIMD2_MOUSE (Q8BGB5), 
LIMD2_RAT   (Q4KM31), LIMD_DICDI  (Q9BIW4), LIME_DICDI  (O60952), 
LIMF_DICDI  (Q86I44), LIMG_DICDI  (Q55DS4), LIMK1_CHICK (Q8QFP8), 
LIMK1_DROME (Q8IR79), LIMK1_HUMAN (P53667), LIMK1_MOUSE (P53668), 
LIMK1_RAT   (P53669), LIMK1_XENLA (O42565), LIMK2_BOVIN (Q32L23), 
LIMK2_CHICK (P53666), LIMK2_HUMAN (P53671), LIMK2_MOUSE (O54785), 
LIMK2_RAT   (P53670), LIMKA_DICDI (Q54L00), LIMKB_DICDI (P0CD62), 
LIMS1_HUMAN (P48059), LIMS1_MOUSE (Q99JW4), LIMS2_BOVIN (Q2KJ33), 
LIMS2_HUMAN (Q7Z4I7), LIMS2_MOUSE (Q91XD2), LIMS3_HUMAN (P0CW19), 
LIMS4_HUMAN (P0CW20), LIN11_CAEEL (P20154), LMCD1_BOVIN (Q17QE2), 
LMCD1_HUMAN (Q9NZU5), LMCD1_MOUSE (Q8VEE1), LMCD1_PIG   (Q5PXT2), 
LMO3_BOVIN  (Q2KIA3), LMO3_DANRE  (Q503U0), LMO3_HUMAN  (Q8TAP4), 
LMO3_MOUSE  (Q8BZL8), LMO3_PONAB  (Q5RBW7), LMO3_RAT(Q99MB5), 
LMO3_XENLA  (Q9YH16), LMO41_XENTR (Q5FVB2), LMO42_XENTR (Q6DJ06), 
LMO4A_XENLA (Q8AW92), LMO4B_XENLA (Q801P0), LMO4_BOVIN  (Q3SWZ8), 
LMO4_HUMAN  (P61968), LMO4_MOUSE  (P61969), LMO7_HUMAN  (Q8WWI1), 
LMX1A_HUMAN (Q8TE12), LMX1A_MESAU (Q04650), LMX1A_MOUSE (Q9JKU8), 
LMX1B_CHICK (P53413), LMX1B_HUMAN (O60663), LMX1B_MESAU (Q60564), 
LMX1B_MOUSE (O88609), LMX1B_XENLA (Q8UVR3), LNEBL_MOUSE (Q9DC07), 
LPP_CHICK   (Q5F464), LPP_HUMAN   (Q93052), LPP_MOUSE   (Q8BFW7), 
LPP_RAT (Q5XI07), LPXN_HUMAN  (O60711), LPXN_MOUSE  (Q99N69), 
LPXN_RABIT  (Q9N261), LRG1_YEAST  (P35688), MCA2B_DANRE (F1RA39), 
MCA3A_DANRE (F1QH17), MCA3B_DANRE (F1QWK4), MEC3_CAEBR  (P34764), 
MEC3_CAEEL  (P09088), MEC3_CAERE  (P34765), MICA1_BOVIN (F1MH07), 
MICA1_DANRE (E7F9T0), MICA1_HUMAN (Q8TDZ2), MICA1_MOUSE (Q8VDP3), 
MICA1_RAT   (D3ZBP4), MICA2_BOVIN (F1MF74), MICA2_HUMAN (O94851), 
MICA2_MOUSE (Q8BML1), MICA2_RAT   (D4A1F2), MICA2_XENTR (F6QZ15), 
MICA3_BOVIN (G3MWR8), MICA3_HUMAN (Q7RTP6), MICA3_MOUSE (Q8CJ19), 
MILK1_BOVIN (E1BBG2), MILK1_HUMAN (Q8N3F8), MILK1_MOUSE (Q8BGT6), 
MILK1_RAT   (D3ZQL6), MILK2_HUMAN (Q8IY33), MILK2_MOUSE (Q3TN34), 
MILK2_RAT   (D3ZEN0), MLP1_DROME  (P53777), MLP2_DROME  (Q24400), 
NRAP_HUMAN  (Q86VF7), NRAP_MOUSE  (Q80XB4), PAXB_DICDI  (Q8MML5), 
PAXI_CHICK  (P49024), PAXI_HUMAN  (P49023), PAXI_MOUSE  (Q8VI36), 
PAXI_PONAB  (Q5R7I1), PAXI_RAT(Q66H76), PDLI1_BOVIN (Q5E9E1), 
PDLI1_HUMAN (O00151), PDLI1_MOUSE (O70400), PDLI1_RAT   (P52944), 
PDLI2_BOVIN (Q3T0C8), PDLI2_HUMAN (Q96JY6), PDLI2_MACFA (Q9GKU1), 
PDLI2_MOUSE (Q8R1G6), PDLI2_RAT   (Q6AYD6), PDLI3_BOVIN (Q3SYZ8), 
PDLI3_CHICK (Q9PU47), PDLI3_HUMAN (Q53GG5), PDLI3_MOUSE (O70209), 
PDLI3_PIG   (Q6QGC0), PDLI3_RAT   (Q66HS7), PDLI3_XENLA (Q6GLJ6), 
PDLI4_BOVIN (Q3T005), PDLI4_CHICK (Q9PW72), PDLI4_HUMAN (P50479), 
PDLI4_MOUSE (P70271), PDLI4_RAT   (P36202), PDLI5_HUMAN (Q96HC4), 
PDLI5_MOUSE (Q8CI51), PDLI5_RAT   (Q62920), PDLI7_BOVIN (Q3SX40), 
PDLI7_CHICK (Q679P3), PDLI7_DANRE (Q6P7E4), PDLI7_HUMAN (Q9NR12), 
PDLI7_MOUSE (Q3TJD7), PDLI7_RAT   (Q9Z1Z9), PDLI7_XENLA (Q6INU3), 
PIN2_CAEEL  (Q19157), PLI2A_ARATH (O80839), PLI2B_ARATH (Q1ECF5), 
PLI2B_ORYSJ (Q7F9R9), PLI2C_ARATH (Q500W4), PRC3A_XENLA (A8WH69), 
PRC3B_XENLA (A0A1L8F1M4), PRI1A_XENLA (Q90Z06), PRI1B_XENLA (Q90WV2), 
PRIC1_AEDAE (Q174I2), PRIC1_ANOGA (Q7QJT4), PRIC1_DROME (A1Z6W3), 
PRIC1_DROPS (Q292U2), PRIC1_HUMAN (Q96MT3), PRIC1_MOUSE (Q3U5C7), 
PRIC1_RAT   (Q71QF9), PRIC1_XENTR (Q28FG2), PRIC2_HUMAN (Q7Z3G6), 
PRIC2_MOUSE (Q80Y24), PRIC3_HUMAN (O43900), PRIC3_MOUSE (Q80VL3), 
PRIC4_HUMAN (Q2TBC4), PXL1_CAEEL  (Q09476), PXL1_YEAST  (P36166), 
PZF1_CAEEL  (G5EGQ2), RBTN1_BOVIN (Q0P5B3), RBTN1_DANRE (Q8JFQ2), 
RBTN1_HUMAN (P25800), RBTN1_MOUSE (Q924W9), RBTN1_XENLA (Q3B8H4), 
RBTN2_BOVIN (Q1LZ94), RBTN2_DANRE (Q9PTJ3), RBTN2_HUMAN (P25791), 
RBTN2_MOUSE (P25801), RBTN2_XENLA (Q90XH3), RBTN2_XENTR (Q5M8V8), 
RGA1_SCHPO  (O43052), RGA1_YEAST  (P39083), RGA2_YEAST  (Q06407), 
RGA3_SCHPO  (O14014), RGA4_SCHPO  (O74360), SCEL_HUMAN  (O95171), 
SCEL_MOUSE  (Q9EQG3), SF3_HELAN   (P29675), TES_AOTNA   (Q07DW1), 
TES_ATEAB   (Q00PK1), TES_ATEGE   (Q09YL5), TES_BOVIN   (Q2YDE9), 
TES_CALJA   (Q2QLG8), TES_CANLF   (A0M8U6), TES_CHICK   (Q90YH9), 
TES_CHLAE   (Q2IBA3), TES_COLGU   (Q07DZ4), TES_DASNO   (Q07E51), 
TES_EULMM   (Q2IBH0), TES_FELCA   (A0M8S5), TES_HORSE   (Q2QLB2), 
TES_HUMAN   (Q9UGI8), TES_LOXAF   (Q108U9), TES_MICMU   (Q2QL92), 
TES_MONDO   (Q2QLA1), TES_MOUSE   (P47226), TES_MUNMU   (Q09YK3), 
TES_MUNRE   (Q07DX3), TES_MUSPF   (Q07E27), TES_NEONE   (Q07E40), 
TES_NOMLE   (Q07DY3), TES_OTOGA   (Q2QLH9), TES_PANTR   (Q2QLF4), 
TES_PAPAN   (A0M8R4), TES_PIG (Q2QLE3), TES_PLEMO   (Q2QLC3), 
TES_PONAB   (Q5RC52), TES_RABIT   (Q09YN8), TES_RAT (Q2LAP6), 
TES_RHIFE   (Q2IBC3), TES_SAIBB   (Q09YI0), TES_SHEEP   (Q09YJ2), 
TES_XENLA   (Q7ZXE9), TES_XENTR   (Q6DIR5), TGFI1_BOVIN (Q3MHZ4), 
TGFI1_HUMAN (O43294), TGFI1_MOUSE (Q62219), TGFI1_RAT   (Q99PD6), 
TGFI1_XENLA (Q2TCH4), TRIP6_BOVIN (Q3SX26), TRIP6_HUMAN (Q15654), 
TRIP6_MOUSE (Q9Z1Y4), TTX3_CAEEL  (G5EE86), UNC95_CAEEL (Q9NEZ5), 
UNC97_CAEEL (P50464), WLI2A_ARATH (O04193), WLI2B_ARATH (Q9M047), 
WLIM1_ARATH (Q94JX5), WTIP_DANRE  (A8DZE6), WTIP_HUMAN  (A6NIX2), 
WTIP_MOUSE  (Q7TQJ8), WTIP_XENLA  (A9LS46), XIRP2_MOUSE (Q4U4S6), 
Y6787_DICDI (Q55BI0), YOCC_SCHPO  (O74398), ZASP_DROME  (A1ZA47), 
ZN185_HUMAN (O15231), ZN185_MOUSE (Q62394), ZYX_CAEEL   (Q9U3F4), 
ZYX_CHICK   (Q04584), ZYX_HUMAN   (Q15942), ZYX_MOUSE   (Q62523), 
ZYX_XENLA   (A5H447), ZYX_XENTR   (Q0VA45)
» more

UniProtKB/Swiss-Prot
False negative sequences		 7 sequences 

ADCE_DICDI  (Q55GN8), HEL2_SCHPO  (Q76PD2), HEL2_YEAST  (Q05580), 

LASP1_CAEEL (P34416), LHX3_HALRO  (Q25132), MICAL_DROME (Q86BA1), 
Y2098_DICDI (Q55A66)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

LASP1_PIG   (P80171)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
SIR7_DROME  (Q9VAQ1), YEMC_SCHPO  (O14033)


				
	

	

		PDB
[Detailed view]		
		
			70 PDB
			


			1A7I; 1B8T; 1CTL; 1CXX; 1G47; 1IBI; 1IML; 1J2O; 1M3V; 1NYP; 1QLI; 1RUT; 
			
				1U5S; 1V6G; 1WIG; 1WYH; 1X3H; 1X4K; 1X4L; 1X61; 1X62; 1X63; 1X64; 1X68; 
				1X6A; 2CO8; 2COR; 2CU8; 2CUP; 2CUQ; 2CUR; 2D8X; 2D8Y; 2D8Z; 2DFY; 2DJ7; 
				2DLO; 2EGQ; 2EHE; 2JTN; 2KBX; 2L4Z; 2L6Y; 2L6Z; 2LXD; 2LZU; 2MBV; 2MIU; 
				2O10; 2O13; 2RGT; 2XJY; 2XJZ; 2XQN; 2YPA; 3F6Q; 3IXE; 3MMK; 4HI8; 4HI9; 
				4JCJ; 4KFZ; 6CME; 6U4M; 6U4N; 7D2T; 7D2U; 7LT9; 7QB0; 8Y6K
			
			

			» more