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PROSITE entry PS00484


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00484
Entry name [info] THYROGLOBULIN_1_1
Accession [info] PS00484
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-JUL-1999 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00377

Name and characterization of the entry

Description [info] Thyroglobulin type-1 repeat signature.
Pattern [info] 
[FYWHPVAS]-x(3)-C-x(3,4)-[SG]-x-[FYW]-x(3)-Q-x(5,12)-[FYW]-C-[VA]-
x(3,4)-[SG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 123 in 75 different sequences
Number of true positive hits 123 in 75 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.40 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 75 sequences 

COW_DROME   (Q9VCR3), EPCAM_BOVIN (Q3T0L5), EPCAM_CHICK (Q5F381), 

EPCAM_HUMAN (P16422), EPCAM_MACMU (Q1WER1), EPCAM_MOUSE (Q99JW5), 
EPCAM_PIG   (Q75QW1), EPCAM_RAT   (O55159), EQSTC_ACTEQ (P81439), 
HG2A_HUMAN  (P04233), HG2A_MOUSE  (P04441), HG2A_RAT(P10247), 
IBP1_BOVIN  (P24591), IBP1_HUMAN  (P08833), IBP1_ICTTR  (Q6Q484), 
IBP1_MOUSE  (P47876), IBP1_PIG(Q75ZP3), IBP1_RAT(P21743), 
IBP2A_DANRE (Q9PTH3), IBP2_BOVIN  (P13384), IBP2_CHICK  (P49705), 
IBP2_HUMAN  (P18065), IBP2_MOUSE  (P47877), IBP2_PIG(P24853), 
IBP2_RAT(P12843), IBP2_SHEEP  (Q29400), IBP2_XENLA  (Q5XHC5), 
IBP2_XENTR  (A4IIA2), IBP3_BOVIN  (P20959), IBP3_HUMAN  (P17936), 
IBP3_MOUSE  (P47878), IBP3_PIG(P16611), IBP3_RAT(P15473), 
IBP4_BOVIN  (Q05716), IBP4_HUMAN  (P22692), IBP4_MOUSE  (P47879), 
IBP4_PIG(P24854), IBP4_RAT(P21744), IBP4_SHEEP  (Q28893), 
IBP5_BOVIN  (Q05717), IBP5_HUMAN  (P24593), IBP5_MOUSE  (Q07079), 
IBP5_PIG(Q28985), IBP5_RAT(P24594), IBP5_XENLA  (Q90WV8), 
IBP6_BOVIN  (Q05718), IBP6_HUMAN  (P24592), IBP6_MOUSE  (P47880), 
IBP6_RAT(P35572), NID1_HUMAN  (P14543), NID1_MOUSE  (P10493), 
NID2_HUMAN  (Q14112), NID2_MOUSE  (O88322), NID2_RAT(B5DFC9), 
SAX_AQUCT   (P31226), SMOC1_HUMAN (Q9H4F8), SMOC1_MOUSE (Q8BLY1), 
SMOC2_HUMAN (Q9H3U7), SMOC2_MOUSE (Q8CD91), TACD2_HUMAN (P09758), 
TACD2_MOUSE (Q8BGV3), TACD2_RAT   (Q6P9Z6), THYG_BOVIN  (P01267), 
THYG_HUMAN  (P01266), THYG_MOUSE  (O08710), THYG_PIG(F1RRV3), 
THYG_RAT(P06882), TICN1_HUMAN (Q08629), TICN1_MOUSE (Q62288), 
TICN2_HUMAN (Q92563), TICN2_MOUSE (Q9ER58), TICN3_HUMAN (Q9BQ16), 
TICN3_MOUSE (Q8BKV0), TICN3_PONAB (Q5RD69), TK1A_HADIN  (A0A1D0C023)
» more

UniProtKB/Swiss-Prot
False negative sequences		 2 sequences 

IBP2B_DANRE (B3F211), PN16_PHONI  (P84032)


				
	

	

		PDB
[Detailed view]		
		
			28 PDB
			


			1ICF; 1L3H; 1RMJ; 1ZT3; 1ZT5; 2DSQ; 2DSR; 2H7T; 4MZV; 6I07; 6O0D; 6O0E; 
			
				6O0F; 6SCJ; 7B75; 7E5M; 7E5N; 7PEE; 7QTQ; 7UFG; 7WRQ; 8D6P; 8D6Q; 8D6S; 
				8D6T; 8D6U; 8VRW; 8VSP
			
			

			» more