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PROSITE entry PS00485


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General information about the entry

Entry name [info] A_DEAMINASE
Accession [info] PS00485
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00419
Associated ProRule [info] PRU10104

Name and characterization of the entry

Description [info] Adenosine and AMP deaminase signature.
Pattern [info]
[SA]-[LIVM]-[NGS]-[STA]-D-D-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 110 in 110 different sequences
Number of true positive hits 89 in 89 different sequences
Number of 'unknown' hits 0
Number of false positive hits 21 in 21 different sequences
Number of false negative sequences 97
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 80.91 %
Recall (true positives / (true positives + false negatives)) 47.85 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 5
Site [info] active_site(?) at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
89 sequences

ADA_BOVIN   (P56658), ADA_CHICK   (Q5ZKP6), ADA_DANRE   (Q6DG22), 
ADA_HUMAN   (P00813), ADA_MOUSE   (P03958), ADA_PLABA   (A0A509ALD0), 
ADA_PLACD   (K6UCV4), ADA_PLAF7   (Q8IJA9), ADA_PLAGA   (A0A0K1SC59), 
ADA_PLAKN   (A0A1Y3DYH2), ADA_PLAVS   (A5KE01), ADA_RAT (Q920P6), 
ADA_XENLA   (Q6GP70), ADA_XENTR   (Q63ZU0), ADDL_STRCO  (Q9L0L6), 
ADDL_STRVG  (P53984), ADD_ECO24   (A7ZM83), ADD_ECO27   (B7URW2), 
ADD_ECO45   (B7M9X6), ADD_ECO55   (B7L5H5), ADD_ECO57   (Q8X661), 
ADD_ECO5E   (B5Z457), ADD_ECO7I   (B7NU11), ADD_ECO81   (B7MVA0), 
ADD_ECO8A   (B7M0H9), ADD_ECOBW   (C4ZY85), ADD_ECODH   (B1XF88), 
ADD_ECOHS   (A8A0G5), ADD_ECOK1   (A1ABG8), ADD_ECOL5   (Q0THK5), 
ADD_ECOL6   (Q8FH99), ADD_ECOLC   (B1IQD2), ADD_ECOLI   (P22333), 
ADD_ECOLU   (B7NB76), ADD_ECOSE   (B6IB57), ADD_ECOSM   (B1LER3), 
ADD_ECOUT   (Q1RBH5), ADD_KLEP3   (B5XWQ7), ADD_KLEP7   (A6T9W8), 
ADD_PHOLL   (Q7N4H5), ADD_PROMH   (B4EVZ1), ADD_SALA4   (B5F6I4), 
ADD_SALDC   (B5FIE1), ADD_SALEP   (B5QUG0), ADD_SALG2   (B5RAJ6), 
ADD_SALHS   (B4THP5), ADD_SALNS   (B4T5A0), ADD_SALPC   (C0Q502), 
ADD_SALSV   (B4TVC7), ADD_SALTI   (Q8Z6R2), ADD_SALTY   (Q8ZPL9), 
ADD_SERP5   (A8GE12), ADD_SHEPC   (A4YCD7), ADD_SHESA   (A0L2R5), 
ADD_SHESM   (Q0HD92), ADD_SHESR   (Q0HPH4), ADD_SHESW   (A1RDZ6), 
ADD_SHIDS   (Q32FF0), ADD_SHIF8   (Q0T4F4), ADD_SHIFL   (Q83RC0), 
ADD_SHISS   (Q3Z1X8), ADD_YERE8   (A1JML4), ADD_YERP3   (A7FHX5), 
ADD_YERPB   (B2K4L5), ADD_YERPS   (Q66AF0), ADD_YERPY   (B1JKL9), 
ADE_ASPFU   (Q4X1Q4), ADE_ASPOR   (Q2TZN9), ADE_CANAL   (Q59ZB1), 
ADE_CANGA   (Q6FP78), ADE_EMENI   (Q8X1T6), ADE_GIBZE   (Q4IMJ1), 
ADE_KLULA   (Q6CM42), ADE_YEAST   (P53909), AMPD1_HUMAN (P23109), 
AMPD1_MOUSE (Q3V1D3), AMPD1_RAT   (P10759), AMPD2_HUMAN (Q01433), 
AMPD2_MOUSE (Q9DBT5), AMPD2_RAT   (Q02356), AMPD3_HUMAN (Q01432), 
AMPD3_MOUSE (O08739), AMPD3_RAT   (O09178), AMPD_ARATH  (O80452), 
AMPD_DICDI  (Q54DD0), AMPD_ORYSJ  (Q84NP7), AMPD_SCHPO  (P50998), 
AMPD_YEAST  (P15274), CADD_LEPIC  (Q72V44)
» more

UniProtKB/Swiss-Prot
False negative sequences
97 sequences

ADA2_DANRE  (P58781), ADA2_DICDI  (Q553U5), ADA2_HUMAN  (Q9NZK5), 
ADA2_PIG(P58780), ADA2_PONAB  (Q5RC46), ADA2_XENLA  (Q2VQV9), 
ADALA_XENLA (Q4V831), ADAL_ARATH  (Q8LPL7), ADAL_BOVIN  (Q0VC13), 
ADAL_CAEEL  (Q8IG39), ADAL_DANRE  (Q4V9P6), ADAL_DROME  (Q9VHH7), 
ADAL_DROPS  (Q295P6), ADAL_HUMAN  (Q6DHV7), ADAL_MOUSE  (Q80SY6), 
ADD1_STRCO  (Q9AK25), ADD2_STRCO  (Q9X7T2), ADDL_OPITP  (B1ZYW1), 
ADDL_TREPA  (O83085), ADDL_TREPS  (B2S1Z3), ADD_ALIF1   (Q5E8Q8), 
ADD_ALIFM   (B5FFC4), ADD_CLOAB   (Q97EV1), ADD_CLOB1   (A7FSN7), 
ADD_CLOB6   (C3L357), ADD_CLOBH   (A5I0I2), ADD_CLOBJ   (C1FVJ1), 
ADD_CLOBK   (B1IHX4), ADD_CLOBL   (A7GC28), ADD_CLOBM   (B1KY93), 
ADD_CLOK1   (B9DZX5), ADD_CLOK5   (A5N6F5), ADD_CLOP1   (Q0TME7), 
ADD_CLOPE   (Q8XHH8), ADD_CLOPS   (Q0SQ45), ADD_EDWI9   (C5BDE0), 
ADD_ENT38   (A4W9X4), ADD_ENTFA   (Q839J4), ADD_ERWT9   (B2VK11), 
ADD_HAEDU   (Q7VNV1), ADD_LACCB   (B3W9T6), ADD_LACLA   (Q9CIR9), 
ADD_LACP3   (Q036B8), ADD_MYCA1   (A0QKJ4), ADD_MYCA9   (B1MFZ9), 
ADD_MYCBO   (P63908), ADD_MYCBP   (A1KP00), ADD_MYCGI   (A4TEW1), 
ADD_MYCLB   (B8ZUW8), ADD_MYCLE   (Q9CCL9), ADD_MYCMM   (B2HDU8), 
ADD_MYCPA   (Q73UD0), ADD_MYCSJ   (A3PVY4), ADD_MYCSK   (A1UCA4), 
ADD_MYCSS   (Q1BCN9), ADD_MYCTA   (A5U7Y8), ADD_MYCTU   (P63907), 
ADD_MYCUA   (A0PNJ1), ADD_MYCVP   (A1T5H1), ADD_PECAS   (Q6D4X4), 
ADD_PECCP   (C6DH28), ADD_PSET1   (Q3IF68), ADD_SHEAM   (A1S1P1), 
ADD_SHEB2   (B8EDT7), ADD_SHEB5   (A3CYL9), ADD_SHEB8   (A6WUH7), 
ADD_SHEB9   (A9KWZ3), ADD_SHEDO   (Q12I24), ADD_SHEFN   (Q08A11), 
ADD_SHEHH   (B0TT81), ADD_SHELP   (A3QJD9), ADD_SHEON   (Q8E8D4), 
ADD_SHEPA   (A8H819), ADD_SHEPW   (B8CV32), ADD_SHEWM   (B1KHA6), 
ADD_SHIB3   (B2U2C1), ADD_SHIBS   (Q320Y0), ADD_STRA1   (Q3K2D4), 
ADD_STRA3   (P63909), ADD_STRA5   (P63910), ADD_STRE4   (C0M691), 
ADD_STREM   (B4U295), ADD_STRMU   (Q8DTN8), ADD_STRS7   (C0MHB1), 
ADD_STRT2   (Q5M4W6), ADD_STRTD   (Q03L81), ADD_VIBA3   (B7VQ44), 
ADD_VIBC3   (A5F4Q2), ADD_VIBCH   (Q9KNI7), ADD_VIBCM   (C3LSH8), 
ADD_VIBPA   (Q87TF3), ADD_VIBVU   (Q8D6Q8), ADD_VIBVY   (Q7MDL6), 
AGSA_APLCA  (P15287), MQNX_ACIC1  (A0LRH8), MQNX_STRAW  (Q82K09), 
MQNX_STRCO  (O86737)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
3 sequences

ADA2_CHICK  (P84520), AMPD1_CHICK (P81073), AMPD1_RABIT (P81072)

		
UniProtKB/Swiss-Prot
False positive sequences
21 sequences

AGRV1_HUMAN (Q8WXG9), CH60_SYNWW  (Q0AVV1), CYCH_BRADU  (P45399), 
GIP3_YEAST  (Q03016), GPL_GLOFF   (Q8MUG0), IPYR1_CHLRE (Q93Y52), 
ISPD_VIBCH  (Q9KUJ2), PURO_NATPD  (Q3ITS6), RTC5_AJECN  (A6RBC0), 
SOMA_SIGGU  (Q9IBE5), SYH_LISIN   (Q92BJ3), SYH_LISMF   (Q71ZF0), 
SYH_LISMO   (Q8Y708), TLN2_HUMAN  (Q9Y4G6), UB10A_XENLA (Q2NL57), 
UB10B_XENLA (Q7ZXR7), UBP10_XENTR (Q6DIJ4), URED_ALKEH  (Q0ACA1), 
YVRB_BACSU  (O34451), ZUPT_XANAC  (Q8PKQ5), ZUPT_XANCP  (Q8P8Z6)
» more

PDB
[Detailed view]
38 PDB

1A4L; 1A4M; 1ADD; 1KRM; 1NDV; 1NDW; 1NDY; 1NDZ; 1O5R; 1QXL; 1UIO; 1UIP; 1UML; 1V79; 1V7A; 1VFL; 1W1I; 1WXY; 1WXZ; 2A3L; 2ADA; 2BGN; 2E1W; 2PGF; 2PGR; 2QVN; 2Z7G; 3EWC; 3EWD; 3IAR; 3KM8; 3MVI; 3MVT; 6II7; 6N9M; 7RTG; 8HU6; 8HUB
» more