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PROSITE entry PS00487


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General information about the entry

Entry name [info] IMP_DH_GMP_RED
Accession [info] PS00487
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00391

Name and characterization of the entry

Description [info] IMP dehydrogenase / GMP reductase signature.
Pattern [info]
[LIVMT]-[RK]-[LIVM]-G-[LIVM]-G-x-G-[SRK]-[LIVMAT]-C-x-T.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_03 which contains 571'609 sequence entries.


Total number of hits 280 in 280 different sequences
Number of true positive hits 280 in 280 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.29 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] IMP_binding(?) at position 11
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
280 sequences

GMPR1_HUMAN (P36959), GMPR1_MOUSE (Q9DCZ1), GMPR1_RAT   (Q9Z244), 
GMPR2_BOVIN (Q32L93), GMPR2_HUMAN (Q9P2T1), GMPR2_MOUSE (Q99L27), 
GMPR_ASCSU  (P27442), GMPR_CAEEL  (O16294), GMPR_LEIDO  (E9BDA8), 
GMPR_LEIMA  (Q4QEB3), GMPR_ONCVO  (Q9NJD8), GMPR_PHYIN  (P59075), 
GUAC_ACIET  (B9ME75), GUAC_ACISJ  (A1WB23), GUAC_AERHH  (A0KN65), 
GUAC_AERS4  (A4SJY8), GUAC_ALBFT  (Q21U05), GUAC_ALIF1  (Q5DZN1), 
GUAC_ALIFM  (B5EUG3), GUAC_ALISL  (B6ERC3), GUAC_BACAH  (A0RLN5), 
GUAC_BACAN  (Q81JJ9), GUAC_BACC1  (Q72WY4), GUAC_BACCR  (Q814I1), 
GUAC_BACCZ  (Q630E8), GUAC_BACHK  (Q6HAI0), GUAC_BACLD  (Q65LF6), 
GUAC_BACSU  (O05269), GUAC_BACVZ  (A7Z8C3), GUAC_BUCA5  (B8D903), 
GUAC_BUCAI  (P57300), GUAC_BUCAP  (Q8K9U0), GUAC_BUCAT  (B8D7A8), 
GUAC_BUCBP  (P59443), GUAC_CITK8  (A8ALJ2), GUAC_CLOAB  (Q97DK4), 
GUAC_DELAS  (A9BNR6), GUAC_ECO24  (A7ZHJ5), GUAC_ECO27  (B7UIF3), 
GUAC_ECO45  (B7MAM6), GUAC_ECO55  (B7LFX2), GUAC_ECO57  (Q8X984), 
GUAC_ECO5E  (B5YZD9), GUAC_ECO7I  (B7NI65), GUAC_ECO81  (B7MNW1), 
GUAC_ECO8A  (B7M145), GUAC_ECOBW  (C4ZRJ8), GUAC_ECODH  (B1XC80), 
GUAC_ECOHS  (A7ZW55), GUAC_ECOK1  (A1A7E7), GUAC_ECOL5  (Q0TLN6), 
GUAC_ECOL6  (P60561), GUAC_ECOLC  (B1IQN5), GUAC_ECOLI  (P60560), 
GUAC_ECOLU  (B7N7X5), GUAC_ECOSE  (B6HZ81), GUAC_ECOSM  (B1LG40), 
GUAC_ECOUT  (Q1RG92), GUAC_EDWI9  (C5B9H0), GUAC_ENT38  (A4W6K6), 
GUAC_ENTFA  (Q831S1), GUAC_ESCF3  (B7LWQ6), GUAC_EXIS2  (B1YH73), 
GUAC_EXISA  (C4L088), GUAC_HELPG  (B5Z7L6), GUAC_HELPH  (Q1CT17), 
GUAC_HELPJ  (Q9ZKZ2), GUAC_HELPS  (B2USX4), GUAC_HELPY  (O25525), 
GUAC_KLEP3  (B5Y1T3), GUAC_KLEP7  (A6T4P6), GUAC_LACAC  (Q5FHY3), 
GUAC_LACCB  (B3WCK9), GUAC_LACDA  (Q1GBV3), GUAC_LACDB  (Q04CB0), 
GUAC_LACGA  (Q045S8), GUAC_LACJO  (P60565), GUAC_LACLA  (Q9CGF1), 
GUAC_LACLM  (A2RL29), GUAC_LACLS  (Q02Z38), GUAC_LACP3  (Q03AR1), 
GUAC_LACPL  (Q88SV5), GUAC_LATSS  (Q38YF0), GUAC_LEPCP  (B1XWM8), 
GUAC_LEVBA  (Q03TT0), GUAC_LIGS1  (Q1WT04), GUAC_LYSSC  (B1HNS5), 
GUAC_MESFL  (Q6F1U6), GUAC_OCEIH  (Q8ERJ2), GUAC_OENOB  (Q04GD9), 
GUAC_PARC0  (A1TNF7), GUAC_PEDPA  (Q03GJ0), GUAC_PHOPR  (Q6LGK4), 
GUAC_POLNA  (A1VMA8), GUAC_POLSJ  (Q12CT8), GUAC_SALA4  (B5F7X8), 
GUAC_SALAR  (A9MQA3), GUAC_SALCH  (Q57TB5), GUAC_SALDC  (B5FI86), 
GUAC_SALEP  (B5R2N9), GUAC_SALG2  (B5RH79), GUAC_SALHS  (B4TJA0), 
GUAC_SALNS  (B4SU63), GUAC_SALPA  (Q5PDH8), GUAC_SALPB  (A9MZN3), 
GUAC_SALPC  (C0Q5K1), GUAC_SALPK  (B5BLD7), GUAC_SALSV  (B4TXJ0), 
GUAC_SALTI  (Q8Z9F9), GUAC_SALTY  (Q8ZRT5), GUAC_SERP5  (A8G9U1), 
GUAC_SHEHH  (B0TQE1), GUAC_SHEPA  (A8HAF6), GUAC_SHIB3  (B2U2A9), 
GUAC_SHIBS  (Q326D1), GUAC_SHIDS  (Q32JY8), GUAC_SHIF8  (Q0T894), 
GUAC_SHIFL  (Q83SM9), GUAC_SHISS  (Q3Z5Q5), GUAC_SHOC1  (Q5WD10), 
GUAC_STAA1  (A7X1Z1), GUAC_STAA2  (A6U1F7), GUAC_STAA3  (Q2FH96), 
GUAC_STAA8  (Q2FYU4), GUAC_STAA9  (A5ISL9), GUAC_STAAB  (Q2YXS9), 
GUAC_STAAC  (Q5HG83), GUAC_STAAE  (A6QGN9), GUAC_STAAM  (P60562), 
GUAC_STAAN  (P60563), GUAC_STAAR  (Q6GH69), GUAC_STAAS  (Q6G9M1), 
GUAC_STAAW  (P60564), GUAC_STACT  (B9DP67), GUAC_STAEQ  (Q5HPK5), 
GUAC_STAES  (Q8CPC9), GUAC_STAHJ  (Q4L646), GUAC_STAS1  (Q49XD2), 
GUAC_STRA1  (Q3K110), GUAC_STRA3  (Q8E578), GUAC_STRA5  (Q8DZL4), 
GUAC_STRE4  (C0MAM1), GUAC_STRGC  (A8AXD6), GUAC_STRP1  (Q99ZQ1), 
GUAC_STRP2  (Q04K71), GUAC_STRP3  (P0DB90), GUAC_STRP4  (B5E4Y3), 
GUAC_STRP6  (Q5XC75), GUAC_STRP7  (C1C7M7), GUAC_STRP8  (Q8P129), 
GUAC_STRPB  (Q1JBS5), GUAC_STRPC  (Q1JLQ8), GUAC_STRPD  (Q1JGV8), 
GUAC_STRPF  (Q1J6M7), GUAC_STRPG  (A2REI5), GUAC_STRPI  (B1IC44), 
GUAC_STRPJ  (B8ZJR9), GUAC_STRPM  (Q48TL6), GUAC_STRPN  (Q97QG5), 
GUAC_STRPQ  (P0DB91), GUAC_STRPS  (B2IPN4), GUAC_STRPZ  (B5XLI1), 
GUAC_STRR6  (Q8DPJ7), GUAC_STRS2  (A4W0T4), GUAC_STRS7  (C0MF02), 
GUAC_STRSY  (A4VUJ2), GUAC_STRU0  (B9DS39), GUAC_STRZJ  (C1CEK5), 
GUAC_STRZP  (C1CKY8), GUAC_STRZT  (C1CR55), GUAC_TOLAT  (C4LAB3), 
GUAC_VARPS  (C5CT60), GUAC_VEREI  (A1WIJ3), GUAC_VIBA3  (B7VS90), 
GUAC_VIBC1  (A7N204), GUAC_VIBC3  (A5EYL9), GUAC_VIBCH  (Q9KMW9), 
GUAC_VIBCM  (C3LUL9), GUAC_VIBPA  (Q87H06), GUAC_VIBVU  (Q8D632), 
GUAC_VIBVY  (Q7MD57), GUAC_YERE8  (A1JJK8), GUAC_YERP3  (A7FM52), 
GUAC_YERPA  (Q1C3T0), GUAC_YERPB  (B2K4G3), GUAC_YERPE  (Q8ZBI2), 
GUAC_YERPG  (A9R1J4), GUAC_YERPN  (Q1CLY8), GUAC_YERPP  (A4TPS6), 
GUAC_YERPS  (Q66EJ0), GUAC_YERPY  (B1JK64), IMDH1_ARATH (P47996), 
IMDH1_BOVIN (A0JNA3), IMDH1_DANRE (Q6GMG5), IMDH1_HUMAN (P20839), 
IMDH1_MOUSE (P50096), IMDH1_RAT   (D3ZLZ7), IMDH1_XENTR (F6S675), 
IMDH1_YEAST (P39567), IMDH2_ARATH (Q9SA34), IMDH2_BOVIN (Q3SWY3), 
IMDH2_CRIGR (P12269), IMDH2_DANRE (B0UXP9), IMDH2_HUMAN (P12268), 
IMDH2_MOUSE (P24547), IMDH2_RAT   (E9PU28), IMDH2_XENTR (F7CYY5), 
IMDH2_YEAST (P38697), IMDH3_DANRE (Q5RGV1), IMDH3_YEAST (P50095), 
IMDH4_YEAST (P50094), IMDH_ACICA  (P31002), IMDH_AQUAE  (O67820), 
IMDH_ASPFU  (Q4WHZ9), IMDH_BACSU  (P21879), IMDH_BIFLO  (Q8G3N6), 
IMDH_BORBU  (P49058), IMDH_CAEEL  (Q9GZH3), IMDH_CANAL  (Q59Q46), 
IMDH_CANAX  (O00086), IMDH_CHLP8  (O50316), IMDH_CHLTE  (Q8KCW4), 
IMDH_CRYNJ  (Q5KP44), IMDH_CRYPV  (Q8T6T2), IMDH_DICDI  (Q54QQ0), 
IMDH_DROME  (Q07152), IMDH_ECO57  (P0ADG8), IMDH_ECOLI  (P0ADG7), 
IMDH_HAEIN  (P44334), IMDH_HALH5  (Q9KGN8), IMDH_HALSA  (Q9HQU4), 
IMDH_HELPJ  (Q9ZL14), IMDH_HELPY  (P56088), IMDH_KORCO  (B1L5U5), 
IMDH_LEIDO  (P21620), IMDH_LEPIN  (Q8F4Q4), IMDH_METJA  (Q59011), 
IMDH_MYCBO  (P65168), IMDH_MYCLE  (Q49729), IMDH_MYCTO  (P9WKI6), 
IMDH_MYCTU  (P9WKI7), IMDH_NEUCR  (Q7SFX7), IMDH_NITMS  (A9A5Y7), 
IMDH_PASMU  (Q9L6B7), IMDH_PNECA  (Q12658), IMDH_PYRAB  (Q9UY49), 
IMDH_PYRFU  (P42851), IMDH_PYRHO  (O58045), IMDH_RHITR  (Q9KH33), 
IMDH_RHOBA  (Q7UJL3), IMDH_SCHPO  (O14344), IMDH_SHIFL  (P0ADG9), 
IMDH_STAA3  (Q2FJM6), IMDH_STAA8  (Q2G0Y7), IMDH_STAAB  (Q2YVL6), 
IMDH_STAAC  (Q5HIQ7), IMDH_STAAM  (P65169), IMDH_STAAN  (P99106), 
IMDH_STAAR  (Q6GJQ7), IMDH_STAAS  (Q6GC82), IMDH_STAAW  (Q8NY70), 
IMDH_STAEQ  (Q5HRX2), IMDH_STAES  (Q8CMQ7), IMDH_STAHJ  (Q4L385), 
IMDH_STAS1  (Q49UU8), IMDH_STRP1  (P0C0H7), IMDH_STRP3  (P0DB88), 
IMDH_STRP6  (Q5X9A3), IMDH_STRP8  (P68839), IMDH_STRPQ  (P0DB89), 
IMDH_STRPY  (P0C0H6), IMDH_THEAC  (Q9HLK8), IMDH_TOXGO  (Q4VRV8), 
IMDH_TRIFO  (P50097), IMDH_TRYBB  (P50098), IMDH_VIGUN  (Q84XA3), 
IMDH_YERPE  (Q0WD32), MPAF2_PENBR (A0A0B5L585), MPAF_PENBR  (F1DBB2), 
MPAF_PENRF  (W6QIT2)
» more

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

GUAC_CHRVO  (Q7NTY1), GUAC_MYCMS  (Q6MUI1)

		
PDB
[Detailed view]
81 PDB

1AK5; 1B3O; 1EEP; 1JCN; 1JR1; 1LRT; 1ME7; 1ME8; 1ME9; 1MEH; 1MEI; 1MEW; 1NF7; 1NFB; 1PVN; 1YPF; 1ZFJ; 2A1Y; 2A7R; 2BLE; 2BWG; 2BZN; 2C6Q; 2CU0; 3FFS; 4IXH; 4QJ1; 4RV8; 4ZQM; 4ZQN; 4ZQO; 4ZQP; 4ZQR; 5UPU; 5UPV; 6I0M; 6I0O; 6RFU; 6U8E; 6U8N; 6U8R; 6U8S; 6U9O; 6UA2; 6UA4; 6UA5; 6UAJ; 6UC2; 6UDO; 6UDP; 6UDQ; 7OJ1; 7OJ2; 7QBJ; 7QDX; 7QEM; 7RER; 7RES; 7RFE; 7RFF; 7RFG; 7RFH; 7RFI; 7RGD; 7RGI; 7RGL; 7RGM; 7RGQ; 7XLO; 8C51; 8C53; 8CGY; 8FOZ; 8FUZ; 8G8F; 8G9B; 8U7M; 8U7Q; 8U7V; 8U8O; 8U8Y
» more