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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00490


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PURL: https://purl.expasy.org/prosite/signature/PS00490

Direct ScanProsite submission
General information about the entry

Entry name [info] MOLYBDOPTERIN_PROK_2
Accession [info] PS00490
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00392

Name and characterization of the entry

Description [info] Prokaryotic molybdopterin oxidoreductases signature 2.
Pattern [info] 
[STA]-x-[STAC](2)-x(2)-[STA]-D-[LIVMY](2)-L-P-x-[STAC](2)-x(2)-E.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 40 in 40 different sequences
Number of true positive hits 39 in 39 different sequences
Number of 'unknown' hits 1
Number of false positive hits 0
Number of false negative sequences 173
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 18.40 %

Comments [info]

Taxonomic range [info] Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 39 sequences 

BISC_CERSP  (P54934), BISC_ECOLI  (P20099), DMSA_ECOLI  (P18775), 

DMSA_HAEIN  (P45004), DSTOR_CERSP (Q57366), DSTOR_RHOCA (Q52675), 
FDHA1_METMP (Q6LXQ1), FDHA2_METMP (F1SVN3), FDHA_METFO  (P06131), 
FDHA_METJA  (P61159), FDHA_MOOTH  (P77908), FDHF_ECOLI  (P07658), 
NARG_BACSU  (P42175), NARG_BRASZ  (P85097), NARG_ECOLI  (P09152), 
NARG_MYCTO  (P9WJQ2), NARG_MYCTU  (P9WJQ3), NARZ_ECOLI  (P19319), 
NASC_BACSU  (P42434), PHSA_SALTY  (P37600), PSRA_WOLSU  (P31075), 
TORA_ECO57  (P58360), TORA_ECOL6  (Q8CW73), TORA_ECOLI  (P33225), 
TORA_PASMU  (Q9CK41), TORA_SALTI  (Q8Z2M4), TORA_SALTY  (Q8ZKZ7), 
TORA_SHEMA  (O87948), TORA_SHEON  (Q8EHI9), TORA_VIBCH  (Q9KRF0), 
TORA_VIBPA  (Q87QI7), TORA_VIBVU  (Q8D8S3), TORA_VIBVY  (Q7MLQ2), 
TORZ_ECO57  (P58362), TORZ_ECOL6  (Q8CVZ3), TORZ_ECOLI  (P46923), 
TORZ_HAEIN  (P44798), Y006_METJA  (Q60314), YOAE_BACSU  (C0SP82)
» more

UniProtKB/Swiss-Prot
False negative sequences		 173 sequences 

AHY_SYNAC   (Q71EW5), ARRA_CHRAT  (Q5Y818), ARRA_SHESA  (Q7WTU0), 

CLRA_IDEDE  (P60068), DDHA_RHOSU  (Q8GPG4), FDHA_MEGGA  (Q934F5), 
FDHL_BACSU  (Q795Y4), FDHL_STAA3  (Q2FEI5), FDHL_STAA8  (Q2FVV9), 
FDHL_STAAB  (Q2YYT1), FDHL_STAAC  (Q5HDP9), FDHL_STAAM  (Q931G2), 
FDHL_STAAN  (Q99RW4), FDHL_STAAR  (Q6GEC4), FDHL_STAAS  (Q6G711), 
FDHL_STAAW  (Q7A057), FDHL_STAHJ  (Q4L8G8), FDHL_STAS1  (Q49ZN0), 
FDNG_ECOLI  (P24183), FDOG_ECOLI  (P32176), FDXG_HAEIN  (P46448), 
NAPA1_PHOPR (Q6LTV9), NAPA2_PHOPR (Q6LQJ3), NAPA_ACTP2  (A3N277), 
NAPA_ACTP7  (B3H2D1), NAPA_ACTPJ  (B0BR28), NAPA_ACTSZ  (A6VQY7), 
NAPA_AERHH  (A0KIM1), NAPA_AERS4  (A4SPG7), NAPA_AGGAC  (Q8VL02), 
NAPA_AGRFC  (Q8U7P1), NAPA_ALIF1  (Q5E3J6), NAPA_ALIFM  (B5FGW1), 
NAPA_BORBR  (Q7WIQ1), NAPA_BORPA  (Q7W733), NAPA_BORPD  (A9I7M5), 
NAPA_BRADU  (Q89EN5), NAPA_BRASB  (A5ED21), NAPA_BRASO  (A4Z0A1), 
NAPA_CAMC1  (A7ZCK4), NAPA_CAMC5  (A7GZP5), NAPA_CAMFF  (A0RQ36), 
NAPA_CAMHC  (A7I3Y7), NAPA_CAMJ8  (A8FLJ3), NAPA_CAMJE  (Q9PPD9), 
NAPA_CAMJJ  (A1VZC8), NAPA_CAMJR  (Q5HV12), NAPA_CAMLR  (B9KCQ2), 
NAPA_CERS4  (Q53176), NAPA_CITK8  (A8AE11), NAPA_COLP3  (Q487G4), 
NAPA_CUPNH  (P39185), NAPA_CUPPJ  (Q46RX3), NAPA_CUPTR  (B3R8B4), 
NAPA_DECAR  (Q47A87), NAPA_DESDA  (P81186), NAPA_DINSH  (A8LLY9), 
NAPA_ECO24  (A7ZP28), NAPA_ECO27  (B7UFL9), NAPA_ECO45  (B7MFB8), 
NAPA_ECO55  (B7LAM9), NAPA_ECO57  (Q8XE47), NAPA_ECO5E  (B5YWZ7), 
NAPA_ECO7I  (B7NN18), NAPA_ECO81  (B7MXN6), NAPA_ECO8A  (B7M5P6), 
NAPA_ECOBW  (C4ZU48), NAPA_ECODH  (B1X8A2), NAPA_ECOHS  (A8A268), 
NAPA_ECOK1  (A1AD59), NAPA_ECOL5  (Q0TFN6), NAPA_ECOL6  (Q8CVW4), 
NAPA_ECOLC  (B1IY66), NAPA_ECOLI  (P33937), NAPA_ECOLU  (B7N5G7), 
NAPA_ECOSE  (B6I1A4), NAPA_ECOSM  (B1LKV2), NAPA_ECOUT  (Q1R9L3), 
NAPA_ECTM1  (A4XWM0), NAPA_EDWI9  (C5B7B9), NAPA_ESCF3  (B7LJU7), 
NAPA_GLAP5  (B8F7K2), NAPA_HAEDU  (Q7VPJ7), NAPA_HAEI8  (Q4QNJ6), 
NAPA_HAEIE  (A5UAE1), NAPA_HAHCH  (Q2SGV7), NAPA_HELHP  (Q7VJT5), 
NAPA_HISS1  (Q0I5G9), NAPA_HISS2  (B0URQ3), NAPA_LARHH  (C1D9G3), 
NAPA_LEPCP  (B1Y6A6), NAPA_MANSM  (Q65Q72), NAPA_METS4  (B0UCB6), 
NAPA_NAUPA  (B9L8L4), NAPA_NITSB  (A6Q604), NAPA_PARM1  (Q2W3T1), 
NAPA_PARME  (Q93HX3), NAPA_PARPN  (Q56350), NAPA_PARXL  (Q13I15), 
NAPA_PASMU  (Q9CKL8), NAPA_PECAS  (Q6D5Z2), NAPA_PECCP  (C6DK59), 
NAPA_PSEA8  (B7UX15), NAPA_PSEAB  (Q02IZ4), NAPA_PSEAE  (Q9I4G3), 
NAPA_PSEP7  (A6V924), NAPA_PSYIN  (A1SWQ0), NAPA_RALPJ  (B2UBL7), 
NAPA_RHIME  (Q92Z36), NAPA_RHOPB  (Q21AR4), NAPA_SACD2  (Q21PN1), 
NAPA_SALA4  (B5EYU5), NAPA_SALAR  (A9MJZ6), NAPA_SALCH  (Q57M92), 
NAPA_SALDC  (B5FNQ2), NAPA_SALEP  (B5R233), NAPA_SALG2  (B5RC85), 
NAPA_SALHS  (B4TAT3), NAPA_SALNS  (B4SYT3), NAPA_SALPA  (Q5PI61), 
NAPA_SALPB  (A9N5G2), NAPA_SALPC  (C0Q0P2), NAPA_SALPK  (B5BDZ4), 
NAPA_SALSV  (B4TPE6), NAPA_SALTI  (Q8Z570), NAPA_SALTY  (Q8ZNH6), 
NAPA_SERP5  (A8GHJ4), NAPA_SHEDO  (Q12P44), NAPA_SHEHH  (B0TSW5), 
NAPA_SHEON  (Q8EIJ1), NAPA_SHIB3  (B2TV30), NAPA_SHIBS  (Q31Z29), 
NAPA_SHIDS  (Q32I06), NAPA_SHIF8  (Q0T2R8), NAPA_SHIFL  (Q83QV0), 
NAPA_SHISS  (Q3Z001), NAPA_STUS1  (A4VJ11), NAPA_STUST  (Q3HS05), 
NAPA_SYMTH  (Q67QZ1), NAPA_VIBA3  (B7VRL0), NAPA_VIBC1  (A7N7J3), 
NAPA_VIBC3  (A5EZX9), NAPA_VIBCH  (Q9KLR4), NAPA_VIBCM  (C3LVU3), 
NAPA_VIBPA  (Q87GW6), NAPA_VIBVU  (Q8D623), NAPA_VIBVY  (Q7MD44), 
NAPA_WOLSU  (Q7M962), NAPA_YERE8  (A1JL26), NAPA_YERP3  (A7FG75), 
NAPA_YERPA  (Q1C5S8), NAPA_YERPB  (B2K970), NAPA_YERPE  (Q8ZCF3), 
NAPA_YERPG  (A9QZL3), NAPA_YERPN  (Q1CK03), NAPA_YERPP  (A4TMK8), 
NAPA_YERPS  (Q668I0), NAPA_YERPY  (B1JSJ0), NARB_SHEFN  (O33732), 
NARB_SYNE7  (P39458), NARB_SYNY3  (P73448), NASA_HALMT  (I3R634), 
NASA_KLEOX  (Q06457), PCRA_DECAR  (Q47CW6), QRCB_NITV2  (Q72E84), 
SERA_THASE  (Q9S1H0), SRDA_MESS1  (A0A0A8X0K1), TTRA_ARCFU  (O30078), 
TTRA_SALTY  (Q9Z4S6), YJGC_BACSU  (O34720), YNFE_ECOLI  (P77374), 
YNFF_ECOLI  (P77783), YYAE_BACSU  (P37519)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

NUOG_SHEON  (Q8EI34)


				
	

	

		PDB
[Detailed view]		
		
			31 PDB
			


			pdb_00001aa6; pdb_00001dmr; pdb_00001dms; pdb_00001e18; pdb_00001e5v; pdb_00001e60; pdb_00001e61; pdb_00001eu1; pdb_00001fdi; pdb_00001fdo; pdb_00001h5n; pdb_00001q16; 
			
				pdb_00001r27; pdb_00001siw; pdb_00001tmo; pdb_00001y4z; pdb_00001y5i; pdb_00001y5l; pdb_00001y5n; pdb_00002dmr; pdb_00002iv2; pdb_00003dmr; pdb_00003egw; pdb_00003ir5; 
				pdb_00003ir6; pdb_00003ir7; pdb_00004dmr; pdb_00007l5i; pdb_00007l5s; pdb_00007z0t; pdb_00009h4t
			
			

			» more