PROSITE entry PS00497
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PURL: https://purl.expasy.org/prosite/signature/PS00497
Direct ScanProsite submission
General information about the entry
| Entry name [info] | TYROSINASE_1 |
| Accession [info] | PS00497 |
| Entry type [info] | PATTERN |
| Date [info] |
01-MAY-1991 CREATED;
01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00398 |
Name and characterization of the entry
| Description [info] | Tyrosinase CuA-binding region signature. |
| Pattern [info] |
H-x(4,5)-F-[LIVMFTP]-x-[FW]-H-R-x(2)-[LVMT]-x(3)-E. |
Numerical results [info]
| Total number of hits | 97 in 77 different sequences |
| Number of true positive hits | 97 in 77 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 14 |
| Number of 'partial' sequences | 31 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 87.39 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 7 |
| Site [info] | copper at position 1 |
| Site [info] | copper at position 7 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
77 sequences
GRIF_STRGG (B1VTI5), HC2C_MEGCR (P81732), HCY1_MEGCR (Q10583), HCY2A_RAPVE (P80960), HCY2E_RAPVE (P83040), HCY2_MEGCR (Q10584), HCYA_ENTDO (P12659), HCYB_HELPO (P12031), HCYC_SEPOF (P56824), HCYE_SEPOF (P56825), HCYG_ENTDO (O61363), HCYG_HELPO (P56823), HCYG_SEPOF (P56826), HKM6_ASPHA (P0DUQ0), LAHY_LARTR (Q6UIL3), ORSC_EMENI (Q5AUW8), PHOQ2_DIALO (A0A8J9RRY2), PHQ11_DIALO (A0A8J9R8H5), PHQ12_DIALO (A0A142I737), PPO1_AGABI (Q00024), PPO1_IPOBA (Q9ZP19), PPO2_AGABI (O42713), PPO2_IPOBA (Q9MB14), PPO4_AGABI (C7FF05), PPOA_SOLLC (Q08303), PPOB_SOLLC (Q08304), PPOB_SOLTU (Q06355), PPOC_SOLLC (Q08305), PPOD_SOLLC (Q08306), PPOE_SOLLC (Q08307), PPOF_SOLLC (Q08296), PPO_MALDO (P43309), PPO_PRUAR (O81103), PPO_SPIOL (P43310), PPO_VICFA (Q06215), PPO_VITVI (P43311), TYR1_CAEEL (P34269), TYR1_HAHS4 (A0A261GRE4), TYR3_CAEEL (Q19673), TYRO1_PINMG (H2A0L0), TYRO2_PINMG (H2A0L1), TYRO_ASPFU (Q8J130), TYRO_ASPOR (Q00234), TYRO_BOVIN (Q8MIU0), TYRO_CANLF (P54834), TYRO_CHICK (P55024), TYRO_COTJA (Q08410), TYRO_FELCA (P55033), TYRO_GORGO (Q9BDE0), TYRO_HUMAN (P14679), TYRO_MOUSE (P11344), TYRO_NEUCR (P00440), TYRO_ORYLA (P55025), TYRO_PELLE (Q0MVP0), TYRO_PELNI (Q04604), TYRO_PELSI (P55026), TYRO_PHONA (A7BHQ9), TYRO_PINMA (P86952), TYRO_PODAS (Q92396), TYRO_RHIML (P33180), TYRO_STRAT (P07524), TYRO_STRGA (P06845), TYRO_STRGB (P55022), TYRO_STRLN (P55023), TYRP1_AMBME (P55027), TYRP1_BOVIN (Q8WN57), TYRP1_CARAU (P55028), TYRP1_CHICK (O57405), TYRP1_FELCA (Q2VPW6), TYRP1_HUMAN (P17643), TYRP1_MOUSE (P07147), TYRP2_BOVIN (Q95119), TYRP2_CHICK (O93505), TYRP2_HUMAN (P40126), TYRP2_MOUSE (P29812), TYRP2_PIG (Q4R1H1), USTQ_ASPFN (B8NM74)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
14 sequences
AS1_ANTMA (Q9FRX6), HCY_SCYOL (C0HLU7), HCY_SCYSE (C0HLU8), PHCY1_HOMAM (Q6KF82), PHCY2_HOMAM (Q6KF81), PPO1_SPOLT (Q3ZPT5), PPO2_DROME (Q9V521), PPO3_DROER (Q8I1F6), PPO3_DROME (Q9W1V6), PRP1_BOMMO (Q27451), PRP1_MANSE (O44249), PRP2_BOMMO (Q27452), PRP2_MANSE (Q25519), TYR2_HAHS4 (A0A261GVB1)» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
31 sequences
HCY1_HOMAM (P82296), HCY1_LIODE (P84461), HCY1_MAJSQ (P82302), HCY1_NECPU (P84846), HCY2_HOMAM (P82297), HCY2_LIODE (P84462), HCY2_MAJSQ (P82303), HCY2_PANJA (P82312), HCY3_HOMAM (P82298), HCY3_MAJSQ (P82304), HCY3_PANJA (P82313), HCY4E_MAJSQ (P82306), HCY4_CARMA (P82309), HCY4_HOMAM (P82299), HCY4_MAJSQ (P82305), HCY5_HOMAM (P82300), HCY5_MAJSQ (P82307), HCY6_HOMAM (P82301), HCY6_MAJSQ (P82308), HCYA_CONCC (P84619), HCYB_CONCC (P84620), HCYIA_PANJA (P82310), HCYIB_PANJA (P82311), LEC_PENST (P84821), PHCY_LIODE (P84460), PHCY_LIOHO (P84768), PHCY_LIOMA (P84769), PHCY_NECPU (P84847), PPO3_SARAR (C0HJM0), PPO_ZINOF (P85026), PRP1_SIMDA (P85046)» more |
| PDB [Detailed view] |
28 PDB
pdb_00001bt1; pdb_00001bt2; pdb_00001bt3; pdb_00001bug; pdb_00001js8; pdb_00001lnl; pdb_00002p3x; pdb_00003l6w; pdb_00003qjo; pdb_00004bed; pdb_00005m6b; pdb_00005m8l; pdb_00005m8m; pdb_00005m8n; pdb_00005m8o; pdb_00005m8p; pdb_00005m8q; pdb_00005m8r; pdb_00005m8s; pdb_00005m8t; pdb_00006els; pdb_00006hqi; pdb_00006hqj; pdb_00008b74; pdb_00009ey5; pdb_00009ey6; pdb_00009ey7; pdb_00009ey8 » more |